# Glycerin and palmitoyl pentapeptide-4

Page: https://lovi.care/skincare/sa/ingredients/glycerin-and-palmitoyl-pentapeptide-4

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Work well together

Use them together by applying the [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin) [serum](https://lovi.care/skincare/sa/ingredients/serum) before the peptide cream, because extra moisture helps the peptides work better. Glycerin hydrates the skin to help the peptide absorb more deeply and work more effectively. The shopper can use a gentler strength or apply the products a few minutes apart if the skin feels sensitive.

[Effects of water activity and low molecular weight humectants on skin permeability and hydration dynamics - a double-blind, randomized and controlled study](https://pubmed.ncbi.nlm.nih.gov/24786192/) [The efficiency of humectants as skin moisturizers in the presence of oil](https://pubmed.ncbi.nlm.nih.gov/11301638/)

- [All about glycerin](https://lovi.care/skincare/sa/ingredients/glycerin)
- [All about palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/palmitoyl-pentapeptide-4)

### [Glycerin](https://lovi.care/skincare/sa/ingredients/glycerin) products

- [CeraVe Moisturising Cream](https://lovi.care/skincare/sa/p/cerave/moisturising-cream/for/dry-sensitive-skin) — Superior fit — [SAR 59.00 at Amazon](https://www.amazon.sa/dp/B07CH9XWHR?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [SAR 53.59 at Amazon](https://www.amazon.sa/dp/B07C5XPXDC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Rhode Glazing Milk](https://lovi.care/skincare/sa/p/rhode/glazing-milk/for/dry-skin) — Superior fit — [SAR 190.00 at Amazon](https://www.amazon.sa/dp/B0H684NGLJ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Double Repair Face Moisturizer](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-double-repair-face-moisturizer/for/oily-acne-prone-skin) — High fit
- [Cetaphil Gentle Skin Cleanser](https://lovi.care/skincare/sa/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [SAR 39.95 at Amazon](https://www.amazon.sa/dp/B09ZFCJ963?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Vanicream Daily Facial Moisturizer](https://lovi.care/skincare/sa/p/vanicream/daily-facial-moisturizer/for/dry-skin) — Superior fit — [SAR 99.63 at Amazon](https://www.amazon.sa/dp/B08BW46XXK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Neutrogena Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Olay Regenerist Micro-Sculpting Cream](https://lovi.care/skincare/sa/p/olay/regenerist-micro-sculpting-cream/for/mature-skin) — Superior fit — [SAR 115.83 at Amazon](https://www.amazon.sa/dp/B07BZWWZDV?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/sa/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [SAR 41.35 at Amazon](https://www.amazon.sa/dp/B07CG2TD9F?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Kiehl's Ultra Facial Cream](https://lovi.care/skincare/sa/p/kiehl-s/ultra-facial-cream/for/dark-spots) — Average fit — [SAR 120.00 at Amazon](https://www.amazon.sa/dp/B00C6SV33M?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CeraVe PM Facial Moisturizing Lotion](https://lovi.care/skincare/sa/p/cerave/pm-facial-moisturizing-lotion/for/acne-prone-skin) — Superior fit

## Questions and answers

### Can you use glycerin and palmitoyl pentapeptide-4 together?

Yes, [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin) and [palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/palmitoyl-pentapeptide-4) work well together to enhance hydration and support your skin barrier. You can experience this combination in the Olay Eye Lifting [Serum](https://lovi.care/skincare/sa/ingredients/serum). Lovi gives this pairing a High fit rating.

### Which goes first, glycerin or palmitoyl pentapeptide-4?

Layer a hydrating serum with glycerin beneath your palmitoyl pentapeptide-4 product to enhance hydration and support peptide delivery. Lovi rates this combination as Superior.

### Are glycerin and palmitoyl pentapeptide-4 good for sensitive skin?

Glycerin and palmitoyl pentapeptide-4 work well together to enhance hydration and support the skin barrier. Lovi rates this combination as High for all skin types, including sensitive skin.

## Research on glycerin and palmitoyl pentapeptide-4

- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Use of a Serum With the Infinite Glow® Device Improves Signs of Facial Aging: A Split-Face Case Report Using VISIA Analysis](https://pubmed.ncbi.nlm.nih.gov/42500768/) Palmitoyl pentapeptide-4 · Cureus, 2026

## Other combinations

- Work well together: [Salicylic acid and glycerin](https://lovi.care/skincare/sa/ingredients/salicylic-acid-and-glycerin)
- Keep them apart: [Adapalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/adapalene-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Granactive retinoid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/granactive-retinoid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Hydroxypinacolone retinoate and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/hydroxypinacolone-retinoate-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Pro-retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/pro-retinol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Retinal and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/retinal-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Retinoid blend and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/retinoid-blend-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Retinol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/retinol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Tretinoin and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/tretinoin-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Vitamin A and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/vitamin-a-and-palmitoyl-pentapeptide-4)
- Work well together: [Liposome and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/liposome-and-palmitoyl-pentapeptide-4)
- Work well together: [Microcapsule and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/microcapsule-and-palmitoyl-pentapeptide-4)
- Depends on the strength: [Vitamin C and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/vitamin-c-and-palmitoyl-pentapeptide-4)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Glycerin and bio-placenta peptides](https://lovi.care/skincare/sa/ingredients/glycerin-and-bio-placenta-peptides)
- Work well together: [Glycerin and collagen peptide](https://lovi.care/skincare/sa/ingredients/glycerin-and-collagen-peptide)
- Work well together: [Glycerin and copper peptide](https://lovi.care/skincare/sa/ingredients/glycerin-and-copper-peptide)
- Work well together: [Glycerin and hexapeptide](https://lovi.care/skincare/sa/ingredients/glycerin-and-hexapeptide)
- Work well together: [Glycerin and hexapeptide-9](https://lovi.care/skincare/sa/ingredients/glycerin-and-hexapeptide-9)
- Work well together: [Betaine and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/betaine-and-palmitoyl-pentapeptide-4)
- Work well together: [Hyaluronic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid-and-palmitoyl-pentapeptide-4)
- Work well together: [Glycerin and palmitoyl tripeptide-1](https://lovi.care/skincare/sa/ingredients/glycerin-and-palmitoyl-tripeptide-1)
- Work well together: [Glycerin and peptide-rich plasma](https://lovi.care/skincare/sa/ingredients/glycerin-and-peptide-rich-plasma)
- Work well together: [Glycerin and triple peptide blend](https://lovi.care/skincare/sa/ingredients/glycerin-and-triple-peptide-blend)
- Work well together: [AHA blend glycolic and citric acids and glycerin](https://lovi.care/skincare/sa/ingredients/aha-blend-glycolic-and-citric-acids-and-glycerin)
- Work well together: [Glycerin and citric acid](https://lovi.care/skincare/sa/ingredients/glycerin-and-citric-acid)
- Work well together: [Glycolic acid and glycerin](https://lovi.care/skincare/sa/ingredients/glycolic-acid-and-glycerin)
- Work well together: [Glycerin and lactic acid](https://lovi.care/skincare/sa/ingredients/glycerin-and-lactic-acid)
- Work well together: [Glycerin and mandelic acid](https://lovi.care/skincare/sa/ingredients/glycerin-and-mandelic-acid)
- Depends on the strength: [Niacinamide and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/niacinamide-and-palmitoyl-pentapeptide-4)
- Work well together: [Panthenol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/panthenol-and-palmitoyl-pentapeptide-4)
- Work well together: [Glycerin and tri-ceramide complex](https://lovi.care/skincare/sa/ingredients/glycerin-and-tri-ceramide-complex)
- Work well together: [Bakuchiol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/bakuchiol-and-palmitoyl-pentapeptide-4)
- Work well together: [Arginine and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/arginine-and-palmitoyl-pentapeptide-4)
- Work well together: [GABA and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/gaba-and-palmitoyl-pentapeptide-4)
- Work well together: [Silk amino acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/silk-amino-acids-and-palmitoyl-pentapeptide-4)
- Work well together: [Taurine and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/taurine-and-palmitoyl-pentapeptide-4)
- Work well together: [Palmitoyl pentapeptide-4 and theanine](https://lovi.care/skincare/sa/ingredients/palmitoyl-pentapeptide-4-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/aha-blend-glycolic-and-citric-acids-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Citric acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/citric-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Glycolic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/glycolic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Lactic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/lactic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Mandelic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/mandelic-acid-and-palmitoyl-pentapeptide-4)
- Work well together: [Coenzyme Q10 and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/coenzyme-q10-and-palmitoyl-pentapeptide-4)
- Work well together: [Green tea and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/green-tea-and-palmitoyl-pentapeptide-4)
- Work well together: [Vitamin E and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/vitamin-e-and-palmitoyl-pentapeptide-4)
- Work well together: [Beta-sitosterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/beta-sitosterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Ceramide-building complex and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/ceramide-building-complex-and-palmitoyl-pentapeptide-4)
- Work well together: [Cholesterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/cholesterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosphingosine and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/phytosphingosine-and-palmitoyl-pentapeptide-4)
- Work well together: [Phytosterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/phytosterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Squalene and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/squalene-and-palmitoyl-pentapeptide-4)
- Work well together: [Tri-ceramide complex and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/tri-ceramide-complex-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Salicylic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/salicylic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Baking soda and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/baking-soda-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Bleach and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/bleach-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Potassium hydroxide and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/potassium-hydroxide-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Behenyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/behenyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Isopropyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/isopropyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Polyvinyl alcohol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/polyvinyl-alcohol-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Copper and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/copper-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Benzoyl peroxide and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/benzoyl-peroxide-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Magnesium and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/magnesium-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Zinc and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/zinc-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Zinc sulfate and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/zinc-sulfate-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Azelaic acid and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/azelaic-acid-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Protease and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/protease-and-palmitoyl-pentapeptide-4)
- Keep them apart: [Superoxide dismutase and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/superoxide-dismutase-and-palmitoyl-pentapeptide-4)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- United Kingdom: https://lovi.care/skincare/uk/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Ireland: https://lovi.care/skincare/ie/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Germany: https://lovi.care/skincare/de/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- France: https://lovi.care/skincare/fr/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Italy: https://lovi.care/skincare/it/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Netherlands: https://lovi.care/skincare/nl/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Spain: https://lovi.care/skincare/es/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Canada: https://lovi.care/skincare/ca/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Australia: https://lovi.care/skincare/au/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Singapore: https://lovi.care/skincare/sg/ingredients/glycerin-and-palmitoyl-pentapeptide-4
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/glycerin-and-palmitoyl-pentapeptide-4 (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/glycerin-and-palmitoyl-pentapeptide-4