# Acetyl hexapeptide-3 and cholesterol

Page: https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-cholesterol

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Work well together

Use them together in the same routine, applying the peptide first and the [cholesterol](https://lovi.care/skincare/sa/ingredients/cholesterol) right after. The cholesterol helps your skin absorb the peptide better and makes your skin barrier feel much stronger and smoother. You do not need to change anything since they work wonderfully side by side.

- [All about acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3)
- [All about cholesterol](https://lovi.care/skincare/sa/ingredients/cholesterol)

### [Acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3) products

- [The Ordinary Multi-Peptide + Copper Peptides 1% Serum](https://lovi.care/skincare/sa/p/the-ordinary/multi-peptide-copper-peptides-1-serum/for/mature-skin) — High fit — [SAR 89.78 at Amazon](https://www.amazon.sa/dp/B0FGQFPWYN?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Multi-Peptide + HA Serum](https://lovi.care/skincare/sa/p/the-ordinary/multi-peptide-ha-serum/for/dry-skin) — Superior fit
- [Medik8 Liquid Peptides](https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [SAR 418.50 at Amazon](https://www.amazon.sa/dp/B0DSJNWVV6?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Mer The Treatment Lotion](https://lovi.care/skincare/sa/p/la-mer/the-treatment-lotion/for/mature-skin) — Superior fit — [SAR 793.03 at Amazon](https://www.amazon.sa/dp/B076ZQ7YVB?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Rhode Peptide Glazing Fluid](https://lovi.care/skincare/sa/p/rhode/peptide-glazing-fluid/for/mature-skin) — High fit — [SAR 213.33 at Amazon](https://www.amazon.sa/dp/B0D5KC6LYS?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [The Ordinary Argireline Solution 10%](https://lovi.care/skincare/sa/p/the-ordinary/argireline-solution-10/for/mature-skin) — Average fit
- [Good Molecules Super Peptide Serum](https://lovi.care/skincare/sa/p/good-molecules/super-peptide-serum/for/mature-skin) — High fit — [SAR 113.86 at Amazon](https://www.amazon.sa/dp/B091MTKS35?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Clinique Smart Clinical Repair Wrinkle Correcting Serum](https://lovi.care/skincare/sa/p/clinique/smart-clinical-repair-wrinkle-correcting-serum/for/mature-skin) — Average fit — [SAR 316.97 at Amazon](https://www.amazon.sa/dp/B09FG8TJDD?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [La Mer The Renewal Oil](https://lovi.care/skincare/sa/p/la-mer/the-renewal-oil/for/mature-skin) — High fit — [SAR 1,470.00 at Amazon](https://www.amazon.sa/dp/B0163GAMI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Estée Lauder Micro Essence Treatment Lotion](https://lovi.care/skincare/sa/p/estee-lauder/micro-essence-treatment-lotion/for/oily-acne-prone-skin) — Superior fit — [SAR 244.35 at Amazon](https://www.amazon.sa/dp/B0DB9GHK4Q?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [The INKEY List Collagen Peptide Serum](https://lovi.care/skincare/sa/p/the-inkey-list/collagen-peptide-serum/for/dry-sensitive-skin) — High fit
- [La Mer The Eye Concentrate](https://lovi.care/skincare/sa/p/la-mer/the-eye-concentrate/for/mature-skin) — High fit — [SAR 931.97 at Amazon](https://www.amazon.sa/dp/B085614WX5?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

### [Cholesterol](https://lovi.care/skincare/sa/ingredients/cholesterol) products

- [CeraVe Hydrating Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/hydrating-facial-cleanser/for/dry-skin) — Superior fit — [SAR 53.59 at Amazon](https://www.amazon.sa/dp/B07C5XPXDC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CeraVe Daily Moisturizing Lotion](https://lovi.care/skincare/sa/p/cerave/daily-moisturizing-lotion/for/dry-skin) — Superior fit — [SAR 41.35 at Amazon](https://www.amazon.sa/dp/B07CG2TD9F?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Illiyoon Ceramide Ato Concentrate Cream](https://lovi.care/skincare/sa/p/illiyoon/ceramide-ato-concentrate-cream/for/dry-skin) — High fit — [SAR 157.00 at Amazon](https://www.amazon.sa/dp/B077RTL1HJ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [SkinCeuticals Triple Lipid Restore 2:4:2](https://lovi.care/skincare/sa/p/skinceuticals/triple-lipid-restore-2-4-2/for/dry-skin) — Superior fit — [SAR 212.74 at Amazon](https://www.amazon.sa/dp/B0H21T43KR?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Cetaphil Ceramide Serum](https://lovi.care/skincare/sa/p/cetaphil/ceramide-serum/for/acne-prone-skin) — Superior fit — [SAR 127.65 at Amazon](https://www.amazon.sa/dp/B0CZD72G5W?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Curél Deep Moisture Spray](https://lovi.care/skincare/sa/p/curel/deep-moisture-spray/for/dry-skin) — High fit
- [CeraVe Comforting Eye Makeup Remover](https://lovi.care/skincare/sa/p/cerave/comforting-eye-makeup-remover/for/dry-sensitive-skin) — High fit
- [Thayers Barrier Bestie Ultra Whip Cream](https://lovi.care/skincare/sa/p/thayers/barrier-bestie-ultra-whip-cream/for/dry-sensitive-skin) — High fit
- [Ceradan Cream](https://lovi.care/skincare/sa/p/ceradan/cream/for/dry-sensitive-skin) — High fit
- [Ceradan Skin Barrier Repair Cream](https://lovi.care/skincare/sa/p/ceradan/skin-barrier-repair-cream/for/dry-sensitive-skin) — High fit
- [Neostrata Resurface Lotion Plus](https://lovi.care/skincare/sa/p/neostrata/resurface-lotion-plus/for/combination-skin) — Average fit
- [Aestura Ato Barrier 365 Lotion](https://lovi.care/skincare/sa/p/aestura/ato-barrier-365-lotion/for/sensitive-skin) — Average fit — [SAR 180.27 at Amazon](https://www.amazon.sa/dp/B07S5K16W7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Can you use acetyl hexapeptide-3 and cholesterol together?

Yes, [acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3) and [cholesterol](https://lovi.care/skincare/sa/ingredients/cholesterol) work well together because the lipid components improve peptide absorption and reinforce skin structure. Lovi rates this combination as High fit.

### Which goes first, acetyl hexapeptide-3 or cholesterol?

Acetyl hexapeptide-3 and cholesterol work well together, as lipids like cholesterol help improve peptide absorption and reinforce skin structure.

### Are acetyl hexapeptide-3 and cholesterol good for sensitive skin?

Acetyl hexapeptide-3 and cholesterol work well together because the lipid components improve peptide absorption and reinforce skin structure. Lovi assigns a High fit rating for dry, mature, and barrier-impaired skin.

## Research on acetyl hexapeptide-3 and cholesterol

- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-3 · American Journal of Clinical Dermatology, 2013
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-3 · Annals of Dermatology, 2019
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-3 · Journal of Cosmetic Dermatology, 2017
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-3 · Journal of Cosmetic and Laser Therapy, 2013

## Other combinations

- Keep them apart: [Adapalene and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/adapalene-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and granactive retinoid](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-granactive-retinoid)
- Keep them apart: [Acetyl hexapeptide-3 and hydroxypinacolone retinoate](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-hydroxypinacolone-retinoate)
- Keep them apart: [Pro-retinol and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/pro-retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Retinal and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/retinal-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and retinoid blend](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-retinoid-blend)
- Depends on the strength: [Retinol and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/retinol-and-acetyl-hexapeptide-3)
- Keep them apart: [Tretinoin and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/tretinoin-and-acetyl-hexapeptide-3)
- Keep them apart: [Vitamin A and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/vitamin-a-and-acetyl-hexapeptide-3)
- Work well together: [Liposome and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/liposome-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and microcapsule](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-microcapsule)
- Depends on the strength: [Vitamin C and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/vitamin-c-and-acetyl-hexapeptide-3)
- Work well together: [Niacinamide and cholesterol](https://lovi.care/skincare/sa/ingredients/niacinamide-and-cholesterol)
- Work well together: [Acetyl hexapeptide-3 and betaine](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-betaine)
- Work well together: [Glycerin and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/glycerin-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and hyaluronic acid](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-hyaluronic-acid)
- Depends on the strength: [Niacinamide and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/niacinamide-and-acetyl-hexapeptide-3)
- Work well together: [Panthenol and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/panthenol-and-acetyl-hexapeptide-3)
- Work well together: [Bakuchiol and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/bakuchiol-and-acetyl-hexapeptide-3)
- Work well together: [Arginine and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/arginine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and GABA](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-gaba)
- Work well together: [Silk amino acids and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/silk-amino-acids-and-acetyl-hexapeptide-3)
- Work well together: [Taurine and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/taurine-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and theanine](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-theanine)
- Keep them apart: [AHA blend glycolic and citric acids and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/aha-blend-glycolic-and-citric-acids-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and citric acid](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-citric-acid)
- Keep them apart: [Glycolic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/glycolic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Lactic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/lactic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and mandelic acid](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-mandelic-acid)
- Work well together: [Coenzyme Q10 and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/coenzyme-q10-and-acetyl-hexapeptide-3)
- Work well together: [Green tea and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/green-tea-and-acetyl-hexapeptide-3)
- Work well together: [Vitamin E and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/vitamin-e-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and beta-sitosterol](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-beta-sitosterol)
- Work well together: [Ceramide-building complex and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/ceramide-building-complex-and-acetyl-hexapeptide-3)
- Work well together: [Acetyl hexapeptide-3 and phytosphingosine](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-phytosphingosine)
- Work well together: [Acetyl hexapeptide-3 and phytosterol](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-phytosterol)
- Work well together: [Acetyl hexapeptide-3 and squalene](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-squalene)
- Work well together: [Acetyl hexapeptide-3 and tri-ceramide complex](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-tri-ceramide-complex)
- Work well together: [Bio-placenta peptides and cholesterol](https://lovi.care/skincare/sa/ingredients/bio-placenta-peptides-and-cholesterol)
- Work well together: [Cholesterol and collagen peptide](https://lovi.care/skincare/sa/ingredients/cholesterol-and-collagen-peptide)
- Work well together: [Cholesterol and copper peptide](https://lovi.care/skincare/sa/ingredients/cholesterol-and-copper-peptide)
- Work well together: [Hexapeptide and cholesterol](https://lovi.care/skincare/sa/ingredients/hexapeptide-and-cholesterol)
- Work well together: [Cholesterol and hexapeptide-9](https://lovi.care/skincare/sa/ingredients/cholesterol-and-hexapeptide-9)
- Work well together: [Cholesterol and palmitoyl pentapeptide-4](https://lovi.care/skincare/sa/ingredients/cholesterol-and-palmitoyl-pentapeptide-4)
- Work well together: [Cholesterol and palmitoyl tripeptide-1](https://lovi.care/skincare/sa/ingredients/cholesterol-and-palmitoyl-tripeptide-1)
- Work well together: [Cholesterol and peptide-rich plasma](https://lovi.care/skincare/sa/ingredients/cholesterol-and-peptide-rich-plasma)
- Work well together: [Cholesterol and triple peptide blend](https://lovi.care/skincare/sa/ingredients/cholesterol-and-triple-peptide-blend)
- Work well together: [Hyaluronic acid and cholesterol](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid-and-cholesterol)
- Keep them apart: [Salicylic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/salicylic-acid-and-acetyl-hexapeptide-3)
- Work well together: [AHA blend glycolic and citric acids and cholesterol](https://lovi.care/skincare/sa/ingredients/aha-blend-glycolic-and-citric-acids-and-cholesterol)
- Work well together: [Cholesterol and citric acid](https://lovi.care/skincare/sa/ingredients/cholesterol-and-citric-acid)
- Work well together: [Glycolic acid and cholesterol](https://lovi.care/skincare/sa/ingredients/glycolic-acid-and-cholesterol)
- Work well together: [Lactic acid and cholesterol](https://lovi.care/skincare/sa/ingredients/lactic-acid-and-cholesterol)
- Work well together: [Mandelic acid and cholesterol](https://lovi.care/skincare/sa/ingredients/mandelic-acid-and-cholesterol)
- Keep them apart: [Acetyl hexapeptide-3 and baking soda](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-baking-soda)
- Keep them apart: [Acetyl hexapeptide-3 and bleach](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-bleach)
- Keep them apart: [Acetyl hexapeptide-3 and potassium hydroxide](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-potassium-hydroxide)
- Keep them apart: [Acetyl hexapeptide-3 and behenyl alcohol](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-behenyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and isopropyl alcohol](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-isopropyl-alcohol)
- Keep them apart: [Acetyl hexapeptide-3 and polyvinyl alcohol](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-polyvinyl-alcohol)
- Keep them apart: [Copper and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/copper-and-acetyl-hexapeptide-3)
- Work well together: [Cholesterol and tri-ceramide complex](https://lovi.care/skincare/sa/ingredients/cholesterol-and-tri-ceramide-complex)
- Keep them apart: [Magnesium and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/magnesium-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and zinc](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-zinc)
- Keep them apart: [Acetyl hexapeptide-3 and zinc sulfate](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-zinc-sulfate)
- Keep them apart: [Benzoyl peroxide and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/benzoyl-peroxide-and-acetyl-hexapeptide-3)
- Keep them apart: [Azelaic acid and acetyl hexapeptide-3](https://lovi.care/skincare/sa/ingredients/azelaic-acid-and-acetyl-hexapeptide-3)
- Keep them apart: [Acetyl hexapeptide-3 and protease](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-protease)
- Keep them apart: [Acetyl hexapeptide-3 and superoxide dismutase](https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-superoxide-dismutase)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi checks every pairing with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this pairing advice: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/ingredients/acetyl-hexapeptide-3-and-cholesterol
- United Kingdom: https://lovi.care/skincare/uk/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Ireland: https://lovi.care/skincare/ie/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Germany: https://lovi.care/skincare/de/ingredients/acetyl-hexapeptide-3-and-cholesterol
- France: https://lovi.care/skincare/fr/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Italy: https://lovi.care/skincare/it/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Netherlands: https://lovi.care/skincare/nl/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Spain: https://lovi.care/skincare/es/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Canada: https://lovi.care/skincare/ca/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Australia: https://lovi.care/skincare/au/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Singapore: https://lovi.care/skincare/sg/ingredients/acetyl-hexapeptide-3-and-cholesterol
- Saudi Arabia: https://lovi.care/skincare/sa/ingredients/acetyl-hexapeptide-3-and-cholesterol (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/ingredients/acetyl-hexapeptide-3-and-cholesterol