# Neutrogena vs Medik8

Page: https://lovi.care/skincare/sa/compare/neutrogena-vs-medik8

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Neutrogena and Medik8 are established skincare brands offering distinct approaches to daily care. The American brand is widely loved for its thoughtfully formulated moisturizers, sunscreens, cleansers, toners, and more, which feature key ingredients like [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), and [dimethicone](https://lovi.care/skincare/sa/ingredients/dimethicone), while the British brand covers [serums](https://lovi.care/skincare/sa/ingredients/serum), moisturizers, eye products, toners, and more, built around hyaluronic acid. Neutrogena suits mature skin and skin with dark spots best, whereas Medik8 products fit dry skin and dry sensitive skin best. The brands ultimately differ in their formulations and heritage, as one dates back to 1930 and utilizes glycerin and dimethicone for barrier function and [water](https://lovi.care/skincare/sa/ingredients/water) loss, while the other was founded in 2009 and focuses on advanced serums.

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

This page compares some of the most popular Neutrogena and Medik8 products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg85fe42dae5).

### Popular Neutrogena vs Medik8 products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [SAR 418.50 at Amazon](https://www.amazon.sa/dp/B0DSJNWVV6?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [SAR 272.46 at Amazon](https://www.amazon.sa/dp/B07Y5P314G?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/sa/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [SAR 320.00 at Amazon](https://www.amazon.sa/dp/B002KKZQ84?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [SAR 321.00 at Amazon](https://www.amazon.sa/dp/B08FHWV9KD?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [SAR 268.00 at Amazon](https://www.amazon.sa/dp/B0C823PSTK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/sa/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [SAR 255.35 at Amazon](https://www.amazon.sa/dp/B0CVBM45QZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [SAR 51.99 at Amazon](https://www.amazon.sa/dp/B082PFY9S7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [SAR 99.99 at Amazon](https://www.amazon.sa/dp/B0DFWH7XPZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/sa/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [SAR 86.93 at Amazon](https://www.amazon.sa/dp/B085S7FZTM?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/sa/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [SAR 178.55 at Amazon](https://www.amazon.sa/dp/B01HOHBS6G?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Retinol Regenerating Cream](https://lovi.care/skincare/sa/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/sa/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [SAR 131.00 at Amazon](https://www.amazon.sa/dp/B0DX2V5F69?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## People Say

Neutrogena

Medik8

- Gentle and safe for sensitive skin Mostly Mentioned Mostly Mentioned “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser”
- Deep hydration and plumping Mostly Mentioned Often Mentioned “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM” “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream” “Quenches dry skin instantly — Neutrogena Hydro Boost Hydrating Hydrogel Mask” “Restores moisture — Medik8 Liquid Peptides”
- Lightweight and non-greasy texture Often Mentioned Often Mentioned “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel” “absorbs instantly — Neutrogena COLLAGEN BANK Moisturizer” “Absorbs into skin without residue. — Neutrogena Hydro Boost Hyaluronic Acid Serum” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Improves skin texture and smoothness Sometimes Noted Often Mentioned “smoother skin — Medik8 Surface Radiance Cleanse” “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- Fades dark spots and brightens Rarely Noted Often Mentioned “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “pigmentation lightened slightly — Medik8 Oxy-R Peptides” “Spots have definitely lightened — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- Makeup base compatibility Sometimes Noted Rarely Noted “Foundation glides right over it — Neutrogena Hydro Boost Water Gel” “Concealer doesn't cake or get stuck in crevices — Neutrogena Hydro Boost Eye Gel-Cream” “Works well under makeup — Neutrogena HYDRO BOOST WATER CREAM” “layers well under sunscreen — Medik8 Total Moisture Daily Facial Cream”
- Price and quantity value Sometimes Noted Often Mentioned “Jar is too small for the price — Neutrogena Hydro Boost Water Gel” “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM” “Tube is tiny for the cost — Neutrogena Hydro Boost Eye Gel-Cream” “Expensive per bottle — Medik8 Liquid Peptides”
- Packaging concerns and design issues Sometimes Noted Sometimes Noted “The dropper is not efficient. — Neutrogena Hydro Boost Hyaluronic Acid Serum” “Hate dipping fingers into a jar — Neutrogena Hydro Boost Water Gel” “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3”
- Pilling, flaking, or residue Sometimes Noted Rarely Noted “too oily for my combination skin — Medik8 C-Tetra Serum” “Can feel sticky if over-applied — Medik8 Liquid Peptides” “Oily texture unpleasant — Medik8 Bakuchiol Peptides” “leaves greasy film — Neutrogena Oil-Free Eye Makeup Remover”

### Neutrogena vs Medik8 routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [SAR 65.11 at Amazon](https://www.amazon.sa/dp/B084Q16G8D?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/dry-skin) — Superior fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [SAR 321.00 at Amazon](https://www.amazon.sa/dp/B08FHWV9KD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/sa/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [SAR 234.73 at Amazon](https://www.amazon.sa/dp/B0FMFZRJTD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/dry-skin) — Average fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/dry-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/dry-skin) — Superior fit — [SAR 150.91 at Amazon](https://www.amazon.sa/dp/B08937VD6Z?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/dry-skin) — Average fit — [SAR 115.51 at Amazon](https://www.amazon.sa/dp/B08L88LZ4V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [SAR 99.99 at Amazon](https://www.amazon.sa/dp/B0DFWH7XPZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/dry-skin) — Warning fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/dry-skin) — Low fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Hydro Boost Hydrating Hydrogel Mask](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hydrating-hydrogel-mask/for/dry-skin) — High fit — [SAR 74.18 at Amazon](https://www.amazon.sa/dp/B076V9PK87?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,617.50 · 95% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B00JKSW24A&Quantity.2=1&ASIN.3=B09D7QJP1M&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B08KYV8H21&Quantity.5=1&ASIN.6=B08FHWV9KD&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B0FMFZRJTD&Quantity.8=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 854.76 · 69% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B08937VD6Z&Quantity.3=1&ASIN.4=B08L88LZ4V&Quantity.4=1&ASIN.5=B0DFWH7XPZ&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B01KTJXVI4&Quantity.8=1&ASIN.9=B076V9PK87&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sa/skin/dry-skin)

### Neutrogena vs Medik8 routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/oily-skin) — Average fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/oily-skin) — Caution fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/oily-skin) — Average fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost+ Niacinamide Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-skin) — High fit — [SAR 80.82 at Amazon](https://www.amazon.sa/dp/B0F9LJWVXY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/oily-skin) — Superior fit — [SAR 115.51 at Amazon](https://www.amazon.sa/dp/B08L88LZ4V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/oily-skin) — Average fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/oily-skin) — Average fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/oily-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Clear Pore Cleanser/Mask](https://lovi.care/skincare/sa/p/neutrogena/clear-pore-cleanser-mask/for/oily-skin) — Average fit — [SAR 103.58 at Amazon](https://www.amazon.sa/dp/B000NSIGE6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,762.13 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B08KYV8H21&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 811.22 · 70% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B0F9LJWVXY&Quantity.3=1&ASIN.4=B08L88LZ4V&Quantity.4=1&ASIN.5=B000NWAOHE&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B000NSIGE6&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/oily-skin)

### Neutrogena vs Medik8 routines for combination skin

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/combination-skin) — High fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/combination-skin) — Low fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/combination-skin) — Average fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/combination-skin) — High fit — [SAR 150.91 at Amazon](https://www.amazon.sa/dp/B08937VD6Z?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [SAR 51.99 at Amazon](https://www.amazon.sa/dp/B082PFY9S7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/combination-skin) — High fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/combination-skin) — Average fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/combination-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Clear Pore Cleanser/Mask](https://lovi.care/skincare/sa/p/neutrogena/clear-pore-cleanser-mask/for/combination-skin) — Average fit — [SAR 103.58 at Amazon](https://www.amazon.sa/dp/B000NSIGE6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,871.14 · 93% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B08KYV8H21&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 817.79 · 74% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B08937VD6Z&Quantity.3=1&ASIN.4=B082PFY9S7&Quantity.4=1&ASIN.5=B000NWAOHE&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B000NSIGE6&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/combination-skin)

## Questions and answers

### Neutrogena or Medik8: which is better?

Medik8 is generally better for dry, combination, sensitive, and acne-prone skin on this page, while Neutrogena offers better value and deep hydration.

### What is the difference between Neutrogena and Medik8?

Medik8 fits dry, combination, and sensitive skin with a Superior Lovi level, while Neutrogena achieves an Average level for those skin types. Reviewers find that Medik8 delivers better skin texture improvement and brightening, whereas Neutrogena offers more deeply hydrating moisturizers and better price value.

### Neutrogena or Medik8 for dry skin?

Medik8 is the better choice for dry skin, as its routine fit is rated as Superior compared to Neutrogena's Average fit. The products on this page for Medik8 include deeply hydrating options like Hydr8 B5 Intense, which helps deliver deep hydration and plumping.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Neutrogena or Medik8: which cleanser is better?

Neutrogena has superior cleanser options for sensitive and acne-prone skin with the Ultra Gentle Daily Cleanser, whereas Medik8 features the Surface Radiance Cleanse as a superior choice for oily acne-prone skin and skin with dark spots. Both brands offer targeted cleansing products, but Neutrogena's cleanser maintains a High fit for dry and dry sensitive skin.

### Which is more affordable, Neutrogena or Medik8?

Neutrogena is more affordable, whereas Medik8 comes with a high price point. Reviewers frequently mention Neutrogena for its price and quantity value, while Medik8 is often noted for being expensive.

### Neutrogena or Medik8: which brand performs better for dark spots and mature skin?

Both Neutrogena and Medik8 provide High fit levels for mature skin and skin with dark spots among the products on this page. Medik8 specifically excels in brightening and fading dark spots as well as improving skin texture.

### How do the fragrance options and key ingredients compare between Neutrogena and Medik8 products?

Neutrogena offers 35 out of 39 products on the page without fragrance, while Medik8 has 11 out of 12 fragrance-free options. The key ingredients across the Neutrogena products on this page include [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin), [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), [dimethicone](https://lovi.care/skincare/sa/ingredients/dimethicone), [avobenzone](https://lovi.care/skincare/sa/ingredients/avobenzone), [vitamin C](https://lovi.care/skincare/sa/ingredients/vitamin-c), [salicylic acid](https://lovi.care/skincare/sa/ingredients/salicylic-acid), [retinol](https://lovi.care/skincare/sa/ingredients/retinol), and [homosalate](https://lovi.care/skincare/sa/ingredients/homosalate), whereas Medik8's key ingredients across its products focus on hyaluronic acid.

### Neutrogena or Medik8: which is better suited for combination skin and dry sensitive skin?

Medik8 is better suited for both combination skin and dry sensitive skin, offering a Superior routine fit for each compared to Neutrogena's Average fit levels. Medik8 provides gentle and non-irritating [serums](https://lovi.care/skincare/sa/ingredients/serum) alongside deep hydration.

### Neutrogena or Medik8 for oily skin?

For oily skin, Medik8 has a High routine fit on the products on this page, whereas Neutrogena has an Average routine fit.

### Neutrogena or Medik8: which moisturizer is better?

Medik8 is better for dry skin and dry sensitive skin, offering a Superior routine fit compared to Neutrogena's Average fit for those skin types. Neutrogena's moisturizers help provide deep hydration and plumping for the products on this page, while Medik8 helps deliver gentle, non-irritating serums and deep moisture.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Neutrogena or Medik8 for sensitive skin?

Medik8 is the better choice for sensitive skin, offering a Superior routine fit compared to Neutrogena's Average fit on the products on this page.

### Neutrogena or Medik8 for acne-prone skin?

For acne-prone skin, Medik8 is the better choice with a Superior routine fit compared to Neutrogena's High fit. Medik8's products on this page help improve skin texture and are generally gentle and non-irritating.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Oxybenzone-free formula · International Journal of Pharmaceutics, 2019
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate, Octisalate, Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits](https://pubmed.ncbi.nlm.nih.gov/39761149/) Acetyl dipeptide-31 amide · Journal of Drugs in Dermatology, 2025
- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Hydration complex · Journal of Drugs in Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024

## The brands

- American skincare: [Neutrogena](https://lovi.care/skincare/sa/brands/neutrogena)
- British skincare: [Medik8](https://lovi.care/skincare/sa/brands/medik8)

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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