# Medik8 vs SK-II

Page: https://lovi.care/skincare/sa/compare/medik8-vs-sk-ii

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Medik8 and SK-II are established skincare brands offering distinct approaches to nourishing the complexion. Medik8 provides [serums](https://lovi.care/skincare/sa/ingredients/serum), moisturizers, eye products, and toners built around [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), suiting dry and dry sensitive skin best while utilizing ingredients that lengthen the toxin wrinkle effect duration. Meanwhile, the Japanese brand relies on nourishing moisturizers, targeted serums, restorative masks, clarifying toners, and gentle formulations powered by pitera to suit dry sensitive skin and combination skin through balancing and soothing properties that improve pore area, roughness, and redness. Both differ in their foundational ingredients and regional heritage, offering specific targeted solutions for acne-prone skin, dark spots, and mature concerns.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

This page compares some of the most popular Medik8 and SK-II products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg3e0e367e2e).

### Popular Medik8 vs SK-II products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [SAR 418.50 at Amazon](https://www.amazon.sa/dp/B0DSJNWVV6?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [SAR 272.46 at Amazon](https://www.amazon.sa/dp/B07Y5P314G?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/sa/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [SAR 320.00 at Amazon](https://www.amazon.sa/dp/B002KKZQ84?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [SAR 321.00 at Amazon](https://www.amazon.sa/dp/B08FHWV9KD?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [SAR 268.00 at Amazon](https://www.amazon.sa/dp/B0C823PSTK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/sa/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [SAR 255.35 at Amazon](https://www.amazon.sa/dp/B0CVBM45QZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Skinpower Advanced Cream](https://lovi.care/skincare/sa/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit — [SAR 1,289.20 at Amazon](https://www.amazon.sa/dp/B0CFW488TZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Ultraura Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Spot Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

## People Say

Medik8

SK-II

- Texture and lightweight feel Often Mentioned Mostly Mentioned “drinks right into the skin — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask” “Smoother skin — SK-II Facial Treatment Clear Lotion” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Brightening and glowing skin Often Mentioned Mostly Mentioned “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “Skin looks brighter — SK-II Genoptics Spot Essence” “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic”
- Deep hydration and moisture Often Mentioned Mostly Mentioned “Restores moisture — Medik8 Liquid Peptides” “Instantly quenched the skin — Medik8 Hydr8 B5 Intense” “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream”
- Gentleness and skin sensitivity Mostly Mentioned Rarely Noted “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Great for sensitive — SK-II Genoptics Spot Essence”
- Plumping and smoothing effect Mostly Mentioned Sometimes Noted “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “Reduces fine lines — Medik8 Liquid Peptides” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “skin feels soft as butter — SK-II Facial Treatment Essence”
- High price point and value Often Mentioned Mostly Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “way too expensive — SK-II Facial Treatment Essence”
- Results timeline and effectiveness Sometimes Noted Often Mentioned “Not as effective as retinol — Medik8 Bakuchiol Peptides” “no difference — Medik8 Oxy-R Peptides” “no difference yet — Medik8 Crystal Retinal Ceramide Eye 3” “did absolutely nothing — SK-II Facial Treatment Essence”
- Tackiness, oiliness, and finish Sometimes Noted Rarely Noted “dried to a tacky finish — SK-II Facial Treatment Mask” “quite thick consistency — SK-II Skinpower Advanced Cream” “Need extra moisturizer — SK-II Genoptics Spot Essence” “too oily for my combination skin — Medik8 C-Tetra Serum”
- Unpleasant scent or fragrance issues Not noted Often Mentioned “smells like dirty feet — SK-II Facial Treatment Essence”

### Medik8 vs SK-II routines for dry skin

#### Medik8-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [SAR 65.11 at Amazon](https://www.amazon.sa/dp/B084Q16G8D?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/dry-skin) — Superior fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Bakuchiol Peptides](https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [SAR 321.00 at Amazon](https://www.amazon.sa/dp/B08FHWV9KD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/sa/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [SAR 234.73 at Amazon](https://www.amazon.sa/dp/B0FMFZRJTD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/dry-skin) — Caution fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,617.50 · 95% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B00JKSW24A&Quantity.2=1&ASIN.3=B09D7QJP1M&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B08KYV8H21&Quantity.5=1&ASIN.6=B08FHWV9KD&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B0FMFZRJTD&Quantity.8=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 2,157.75 · 83% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B000H723LU&Quantity.2=1&ASIN.3=B09D7QJP1M&Quantity.3=1&ASIN.4=B084M1R6RH&Quantity.4=1&ASIN.5=B072C3MCDH&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B078MQP5ZF&Quantity.8=1&AssociateTag=lovisa02-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sa/skin/dry-skin)

### Medik8 vs SK-II routines for oily skin

#### Medik8-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/oily-skin) — High fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/oily-skin) — Average fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/oily-skin) — High fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/oily-skin) — Average fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/oily-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,762.13 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B08KYV8H21&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 1,935.93 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/oily-skin)

### Medik8 vs SK-II routines for combination skin

#### Medik8-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/combination-skin) — High fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Press & Glow](https://lovi.care/skincare/sa/p/medik8/press-and-glow/for/combination-skin) — High fit — [SAR 190.36 at Amazon](https://www.amazon.sa/dp/B08KYV8H21?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/combination-skin) — High fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/combination-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/combination-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/combination-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medik8 routine · SAR 1,871.14 · 93% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B00JKSW24A&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B08KYV8H21&Quantity.6=1&ASIN.7=B0CKCMLNRK&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 2,044.94 · 90% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/combination-skin)

## Questions and answers

### Medik8 or SK-II: which is better?

Both brands perform well, but Medik8 has a Lovi fit level of Superior for dry skin compared to SK-II having a fit level of High. Medik8 helps deliver deep hydration with key ingredients like [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), which studies show benefits skin quality and signs of aging.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Medik8 and SK-II?

Medik8 is better for gentleness and plumping, while SK-II excels in texture and brightening. Both brands offer good hydration, but Medik8 has a Superior fit for dry skin.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or SK-II for dry skin?

Medik8 is a better fit for dry skin, achieving a Superior routine fit compared to the High fit from SK-II. Reviewers mention that the products on this page help deliver deep hydration and moisture.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or SK-II: which moisturizer is better?

Medik8 delivers a Superior routine fit for dry skin compared to SK-II's High fit, making Medik8 the stronger choice for targeted moisture. The products on this page feature hyaluronic acid, which helps provide deep hydration.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, Medik8 or SK-II?

Reviewers note that both Medik8 and SK-II have a high price point, but Medik8 is more frequently associated with high price concerns among the products on this page.

### Which brand performs better for brightening and glowing skin, Medik8 or SK-II?

SK-II performs better for brightening and glowing skin. Reviewers note that SK-II provides superior texture and lightweight feel alongside brightening and glowing results.

### Medik8 or SK-II for oily skin?

Medik8 and SK-II are both a High fit for oily skin. Both brands offer products that help manage oiliness well, though their specific formulations and key ingredients differ.

### Medik8 or SK-II for sensitive skin?

Medik8 is a better fit for sensitive skin, earning a Lovi fit level of Superior compared to SK-II's High. Reviewers frequently note that Medik8 offers greater gentleness and less skin sensitivity.

### Medik8 or SK-II for acne-prone skin?

Medik8 achieves a Superior routine fit for acne-prone skin, while SK-II reaches a High fit level on the products on this page. Reviewers note that Medik8 provides better gentleness and skin sensitivity, whereas SK-II offers better texture and lightweight feel.

### Medik8 or SK-II for dry sensitive skin?

Both brands fit dry sensitive skin well, but Lovi rates Medik8 as Superior and SK-II as High. Hyaluronic acid helps provide deep hydration for dry sensitive skin types.

[Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or SK-II for combination skin?

For combination skin, both Medik8 and SK-II achieve a Superior fit level on this page. Reviewers note that Medik8 provides a plumping and smoothing effect, while SK-II offers a lightweight feel.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Concentrated glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate, Tocopheryl acetate vitamin e · Contemporary Clinical Trials Communications, 2021
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [A polyhydroxy acid skin care regimen provides antiaging effects comparable to an alpha-hydroxyacid regimen](https://pubmed.ncbi.nlm.nih.gov/15002657/) Pha polyhydroxy acid · Cutis, 2004
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Shea butter · Lasers in Medical Science, 2025
- [Preclinical Safety Evaluation of Dual Drug-Loaded Nanolipidic Carriers of Dissolvable Patches: In-Vitro and In-Vivo Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/41186117/) Tetrahydrodiferuloylmethane · Molecular Pharmaceutics, 2025
- [Acai Oil-Based Organogel Containing Hyaluronic Acid for Topical Cosmetic: In Vitro and Ex Vivo Assessment](https://pubmed.ncbi.nlm.nih.gov/39339231/) Euterpe oleracea fruit extract · Pharmaceutics, 2024
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026

## The brands

- British skincare: [Medik8](https://lovi.care/skincare/sa/brands/medik8)
- Japanese skincare: [SK-II](https://lovi.care/skincare/sa/brands/sk-ii)

## More comparisons

- [SKIN1004 vs Medik8](https://lovi.care/skincare/sa/compare/skin1004-vs-medik8)
- [SKIN1004 vs SK-II](https://lovi.care/skincare/sa/compare/skin1004-vs-sk-ii)
- [Anua vs Medik8](https://lovi.care/skincare/sa/compare/anua-vs-medik8)
- [Anua vs SK-II](https://lovi.care/skincare/sa/compare/anua-vs-sk-ii)
- [Medicube vs Medik8](https://lovi.care/skincare/sa/compare/medicube-vs-medik8)
- [Medicube vs SK-II](https://lovi.care/skincare/sa/compare/medicube-vs-sk-ii)
- [The Ordinary vs Medik8](https://lovi.care/skincare/sa/compare/the-ordinary-vs-medik8)
- [The Ordinary vs SK-II](https://lovi.care/skincare/sa/compare/the-ordinary-vs-sk-ii)
- [Beauty of Joseon vs Medik8](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-medik8)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-sk-ii)
- [COSRX vs Medik8](https://lovi.care/skincare/sa/compare/cosrx-vs-medik8)
- [COSRX vs SK-II](https://lovi.care/skincare/sa/compare/cosrx-vs-sk-ii)
- [CeraVe vs Medik8](https://lovi.care/skincare/sa/compare/cerave-vs-medik8)
- [CeraVe vs SK-II](https://lovi.care/skincare/sa/compare/cerave-vs-sk-ii)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-sk-ii)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/sa/compare/dr-althea-vs-medik8)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/sa/compare/dr-althea-vs-sk-ii)
- [Some By Mi vs Medik8](https://lovi.care/skincare/sa/compare/some-by-mi-vs-medik8)
- [Some By Mi vs SK-II](https://lovi.care/skincare/sa/compare/some-by-mi-vs-sk-ii)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-sk-ii
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-sk-ii
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-sk-ii
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-sk-ii
- France: https://lovi.care/skincare/fr/compare/medik8-vs-sk-ii
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-sk-ii
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-sk-ii
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-sk-ii
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-sk-ii
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-sk-ii
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-sk-ii
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-sk-ii (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-sk-ii