# Medik8 vs Lancôme

Page: https://lovi.care/skincare/sa/compare/medik8-vs-lancome

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Medik8 and Lancôme are well-regarded skincare names, with the former being a British brand founded in 2009 and owned by L'Oréal Groupe since 2025, and the latter a French brand established in 1935 and owned by L'Oréal S.A. since 1964. Medik8 is known for [serums](https://lovi.care/skincare/sa/ingredients/serum), moisturizers, eye products, toners, and more, which are built around [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), while Lancôme is beloved for its sophisticated moisturizers, eye products, serums, toners, and more, formulated with [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin), hyaluronic acid, and [adenosine](https://lovi.care/skincare/sa/ingredients/adenosine). The British line suits dry skin and dry sensitive skin best, whereas the French brand suits dry, mature, acne-prone, and uneven skin best due to hydrating, smoothing, and restorative properties. They differ because their key ingredients provide distinct benefits, with the former utilizing hyaluronic acid to lengthen toxin wrinkle effect duration, and the latter relying on glycerin, hyaluronic acid, and adenosine to improve skin hydration and barrier function, lengthen the effect of wrinkle reduction, and reduce wrinkles.

Medik8 is a British skincare brand founded in 2009 and owned by L'Oréal Groupe since 2025.

[loreal.com](https://www.loreal.com/en/press-release/group/l-oreal-groupe-to-acquire-a-majority-stake-in-medik8/) [medik8.com](https://www.medik8.com/pages/founders-story) [tracxn.com](https://tracxn.com/d/companies/medik8/__vqs3N9eL3EfvIq0IoeUPADts7CrlGbzm7kjy9M9QY8o)

Lancôme is a French skincare brand founded in 1935 and owned by L'Oréal S.A. since 1964.

[loreal.com](https://www.loreal.com/en/luxe-division/lancome/) [en.wikipedia.org](https://en.wikipedia.org/wiki/Lanc%C3%B4me) [cosmeticsbusiness.com](https://cosmeticsbusiness.com/loreal-lancome-francoise-lehmann-leaves-succeed-vania-lacascade)

This page compares some of the most popular Medik8 and Lancôme products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg11ab91710a).

### Popular Medik8 vs Lancôme products

#### Medik8

- [Liquid Peptides](https://lovi.care/skincare/sa/p/medik8/liquid-peptides/for/oily-acne-prone-skin) — Average fit — [SAR 418.50 at Amazon](https://www.amazon.sa/dp/B0DSJNWVV6?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [CRYSTAL RETINAL 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-3/for/mature-skin) — High fit — [SAR 272.46 at Amazon](https://www.amazon.sa/dp/B07Y5P314G?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [C-Tetra Serum](https://lovi.care/skincare/sa/p/medik8/c-tetra-serum/for/dry-sensitive-skin) — Average fit — [SAR 320.00 at Amazon](https://www.amazon.sa/dp/B002KKZQ84?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Bakuchiol Peptides](https://lovi.care/skincare/sa/p/medik8/bakuchiol-peptides/for/dry-skin) — Superior fit — [SAR 321.00 at Amazon](https://www.amazon.sa/dp/B08FHWV9KD?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Crystal Retinal Ceramide Eye 3](https://lovi.care/skincare/sa/p/medik8/crystal-retinal-ceramide-eye-3/for/mature-skin) — High fit — [SAR 268.00 at Amazon](https://www.amazon.sa/dp/B0C823PSTK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Oxy-R Peptides](https://lovi.care/skincare/sa/p/medik8/oxy-r-peptides/for/mature-skin) — Superior fit — [SAR 399.70 at Amazon](https://www.amazon.sa/dp/B0CKCMLNRK?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Total Moisture Daily Facial Cream](https://lovi.care/skincare/sa/p/medik8/total-moisture-daily-facial-cream/for/mature-skin) — High fit — [SAR 255.35 at Amazon](https://www.amazon.sa/dp/B0CVBM45QZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Hydr8 B5 Intense](https://lovi.care/skincare/sa/p/medik8/hydr8-b5-intense/for/dry-skin) — Superior fit — [SAR 304.00 at Amazon](https://www.amazon.sa/dp/B00JKSW24A?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### Lancôme

- [RÉNERGIE](https://lovi.care/skincare/sa/p/lancome/renergie/for/sensitive-skin) — Average fit
- [Génifique Ultimate](https://lovi.care/skincare/sa/p/lancome/genifique-ultimate/for/sensitive-skin) — High fit
- [Bi-Facil Double Action Eye Makeup Remover](https://lovi.care/skincare/sa/p/lancome/bi-facil-double-action-eye-makeup-remover/for/dry-skin) — Average fit
- [Tonique Confort](https://lovi.care/skincare/sa/p/lancome/tonique-confort/for/dry-sensitive-skin) — High fit
- [HYDRA ZEN](https://lovi.care/skincare/sa/p/lancome/hydra-zen/for/sensitive-skin) — Average fit
- [Advanced Génifique Youth Activating Concentrate](https://lovi.care/skincare/sa/p/lancome/advanced-genifique-youth-activating-concentrate/for/sensitive-skin) — High fit
- [Hydra Zen Gel Cream](https://lovi.care/skincare/sa/p/lancome/hydra-zen-gel-cream/for/sensitive-skin) — Average fit
- [Crème Radiance](https://lovi.care/skincare/sa/p/lancome/creme-radiance/for/dry-skin) — Warning fit

## People Say

Medik8

Lancôme

- Deep hydration and moisture Mostly Mentioned Mostly Mentioned “Restores moisture — Medik8 Liquid Peptides” “Instantly quenched the skin — Medik8 Hydr8 B5 Intense” “gives my skin an instant dewy glow — Lancôme Tonique Confort” “keeps the skin soft and hydrated — Lancôme HYDRA ZEN”
- Lightweight and elegant texture Often Mentioned Mostly Mentioned “absorbs quickly — Lancôme RÉNERGIE” “absorbs almost instantly — Lancôme Génifique Ultimate” “absorbs instantly — Lancôme Advanced Génifique Eye Cream” “absorbed effortlessly — Medik8 Total Moisture Daily Facial Cream”
- Gentle and non-irritating formulation Mostly Mentioned Sometimes Noted “zero irritation or peeling — Medik8 CRYSTAL RETINAL 3” “only Vitamin C my sensitive skin can tolerate — Medik8 C-Tetra Serum” “Best retinol replacement — Medik8 Bakuchiol Peptides” “Doesn't sting my eyes — Lancôme Bi-Facil Double Action Eye Makeup Remover”
- Brightening and radiant glow Often Mentioned Sometimes Noted “I wake up glowing. It adds back that youthful bloom that I've lost. — Medik8 Sleep Glycolic” “unlocked a serious glow — Medik8 C-Tetra Serum” “immediate glow — Medik8 Super C Ferulic” “Skin looks lit from within — Lancôme Advanced Génifique Youth Activating Concentrate”
- Improves skin texture Often Mentioned Sometimes Noted “smoother skin — Medik8 Surface Radiance Cleanse” “skin feels baby soft — Medik8 CRYSTAL RETINAL 3” “skin feels firmer — Medik8 Oxy-R Peptides” “Skin feels cushiony soft — Lancôme Advanced Génifique Youth Activating Concentrate”
- Skin plumping and smoothing Sometimes Noted Sometimes Noted “My skin was smoother, my skin texture felt more resurfaced. — Medik8 Sleep Glycolic” “Reduces fine lines — Medik8 Liquid Peptides” “Face is so soft, smooth and not puffy. — Lancôme Advanced Génifique Night Cream” “skin is softer to touch — Lancôme Absolue Precious Oil”
- High price point Often Mentioned Mostly Mentioned “Expensive per bottle — Medik8 Liquid Peptides” “very expensive for amount — Medik8 CRYSTAL RETINAL 3” “hefty price tag — Medik8 C-Tetra Serum” “super expensive — Lancôme Absolue Precious Oil”
- Packaging issues and design flaws Sometimes Noted Sometimes Noted “Glass bottle breaks easily — Medik8 Liquid Peptides” “hard to get last bit — Medik8 CRYSTAL RETINAL 3” “dispenser stopped working — Lancôme RÉNERGIE” “struggled to open cap — Lancôme Génifique Ultimate”
- Unpleasant smell or scent issues Rarely Noted Often Mentioned “metallic scent — Medik8 Super C Ferulic” “My only issue with it is the fragrance. — Lancôme Hydra Zen Gel Cream”

## Questions and answers

### Medik8 or Lancôme: which is better?

Medik8 stands out for its gentle, non-irritating [serums](https://lovi.care/skincare/sa/ingredients/serum) and superior brightening results, while Lancôme is noted for its lightweight and elegant textures with pleasant scents. Both brands offer products containing [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid) that help improve deep hydration and moisture.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What is the difference between Medik8 and Lancôme?

Medik8 stands out for its gentle, fragrance-free formulas that help brighten skin and improve texture, whereas Lancôme features lightweight, scented products that provide deep hydration. Both brands use hyaluronic acid, which supports skin aging benefits.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medik8 or Lancôme: which cleanser is better?

Medik8 is better for cleansers on this page, as its Surface Radiance Cleanse has a Superior Lovi fit level for acne-prone skin, oily acne-prone skin, and skin with dark spots. In comparison, Lancôme's Crème Radiance on this page has a Warning fit level across all skin types.

### Which is more affordable, Medik8 or Lancôme?

Both Medik8 and Lancôme are high-end skincare brands, and reviewers note a high price point as a drawback for the products on this page for both lines.

### Which causes fewer breakouts, Medik8 or Lancôme?

Medik8 helps provide gentler formulations for breakout-prone skin, as the products on this page show better ratings for acne-prone skin compared to Lancôme.

### Between Medik8 and Lancôme, which brand has better options for fragrance-free skincare?

Medik8 provides better options for fragrance-free skincare because nearly all the products on this page list no fragrance, whereas most Lancôme products include fragrance.

### How do the founding years and corporate ownerships of Medik8 and Lancôme compare?

Medik8 was founded in 2009 in the United Kingdom and has been owned by L'Oréal Groupe since 2025, whereas Lancôme was founded in 1935 in France and has been owned by L'Oréal S.A. since 1964.

### Which brand offers better results for brightening and radiant glow according to reviews?

Medik8 does better for brightening and radiant glow according to reviews. Topical treatments containing [vitamin C](https://lovi.care/skincare/sa/ingredients/vitamin-c) and other brightening agents help improve radiance.

[Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/) [Journal of the American Academy of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18603326/)

### Medik8 or Lancôme: which moisturizer is better?

Medik8 stands out for moisturizers on this page because its Hydr8 B5 Intense achieves a Superior Lovi fit for dry skin, whereas Lancôme moisturizers are limited to an Average or lower fit for that skin type. Topical hyaluronic acid, a key ingredient featured in the products on this page, helps provide deep hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/) [Drug Delivery, 2017](https://pubmed.ncbi.nlm.nih.gov/28155509/)

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Hyaluronic acid · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol vitamin e, Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation](https://pubmed.ncbi.nlm.nih.gov/18603326/) Ferulic acid · Journal of the American Academy of Dermatology, 2008
- [Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin](https://pubmed.ncbi.nlm.nih.gov/19146606/) Ferulic acid · Journal of Cosmetic Dermatology, 2008
- [Production and characterization of cosmetic nanoemulsions containing Opuntia ficus-indica (L.) mill extract as moisturizing agent](https://pubmed.ncbi.nlm.nih.gov/25648593/) Hydrolyzed opuntia ficus-indica flower extract · Molecules, 2015
- [Topical anti-inflammatory effects of isorhamnetin glycosides isolated from Opuntia ficus-indica](https://pubmed.ncbi.nlm.nih.gov/25821823/) Hydrolyzed opuntia ficus-indica flower extract · BioMed Research International, 2015
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Topical delivery of tetrahydrocurcumin lipid nanoparticles effectively inhibits skin inflammation: in vitro and in vivo study](https://pubmed.ncbi.nlm.nih.gov/29938544/) Tetrahydrodiferuloylmethane · Drug Development and Industrial Pharmacy, 2018
- [Vitamin C-squalene bioconjugate promotes epidermal thickening and collagen production in human skin](https://pubmed.ncbi.nlm.nih.gov/33037252/) Squalane · Scientific Reports, 2020
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis extract · Clinical Pharmacology, 2018
- [Urea: a comprehensive review of the clinical literature](https://pubmed.ncbi.nlm.nih.gov/24314769/) Urea · Dermatology Online Journal, 2013
- [Effects of glyceryl glucoside on AQP3 expression, barrier function and hydration of human skin](https://pubmed.ncbi.nlm.nih.gov/22584263/) Glyceryl glucoside · Skin Pharmacology and Physiology, 2012
- [Antioxidant Opuntia ficus-indica Extract Activates AHR-NRF2 Signaling and Upregulates Filaggrin and Loricrin Expression in Human Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/26061570/) Hydrolyzed opuntia ficus-indica flower extract · Journal of Medicinal Food, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Tocopherol vitamin e, Ferulic acid · Journal of Cosmetic Dermatology, 2020
- [Inhibitory effect of mulberroside A and its derivatives on melanogenesis induced by ultraviolet B irradiation](https://pubmed.ncbi.nlm.nih.gov/21946069/) Hydroxyresveratrol · Food and Chemical Toxicology, 2011
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [Treatment of xerosis with a topical formulation containing glyceryl glucoside, natural moisturizing factors, and ceramide](https://pubmed.ncbi.nlm.nih.gov/22916312/) Moisturizing factors nmf, Glyceryl glucoside · The Journal of Clinical and Aesthetic Dermatology, 2012
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Tetrahexyldecyl ascorbate · Photochemistry and Photobiology, 2021
- [Clinical evidence of the efficacy and safety of a new 3-in-1 anti-aging topical night serum-in-oil containing melatonin, bakuchiol, and ascorbyl tetraisopalmitate: 103 females treated from 28 to 84 days](https://pubmed.ncbi.nlm.nih.gov/30924254/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2019
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Gluconolactone, Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin, Panthenol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [The pivotal role of Bifida Ferment Lysate on reinforcing the skin barrier function and maintaining homeostasis of skin defenses in vitro](https://pubmed.ncbi.nlm.nih.gov/37218728/) Bifida lysate ferment · Journal of Cosmetic Dermatology, 2023
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Antioxidant-based topical formulations influence on the inflammatory response of Japanese skin: A clinical study using non-invasive techniques](https://pubmed.ncbi.nlm.nih.gov/28385617/) Tetrahexyldecyl ascorbate · European Journal of Pharmaceutics and Biopharmaceutics, 2017
- [A dermocosmetic containing bakuchiol, Ginkgo biloba extract and mannitol improves the efficacy of adapalene in patients with acne vulgaris: result from a controlled randomized trial](https://pubmed.ncbi.nlm.nih.gov/25914553/) Bakuchiol · Clinical, Cosmetic and Investigational Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Moisturizing factors nmf · Molecules, 2021
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Spent Yeast Waste Streams as a Sustainable Source of Bioactive Peptides for Skin Applications](https://pubmed.ncbi.nlm.nih.gov/36768574/) Yeast · International Journal of Molecular Sciences, 2023
- [Development of stable tocopherol succinate-loaded ethosomes to enhance transdermal permeation: In vitro and in vivo characterizations](https://pubmed.ncbi.nlm.nih.gov/35274433/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Topical application of jojoba (Simmondsia chinensis L.) wax enhances the synthesis of pro-collagen III and hyaluronic acid and reduces inflammation in the ex-vivo human skin organ culture model](https://pubmed.ncbi.nlm.nih.gov/38344180/) Jojoba seed oil · Frontiers in Pharmacology, 2024
- [A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors](https://pubmed.ncbi.nlm.nih.gov/33081083/) Rosa centifolia flower extract · Molecules, 2020
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2021
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Clinical tolerance and efficacy of capryloyl salicylic acid peel compared to a glycolic acid peel in subjects with fine lines/wrinkles and hyperpigmented skin](https://pubmed.ncbi.nlm.nih.gov/19146601/) Capryloyl salicylic acid · Journal of Cosmetic Dermatology, 2008
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Aloe barbadensis flower extract · Molecules, 2024
- [Squalane as a Promising Agent Protecting UV-Induced Inhibition of Collagen Biosynthesis and Wound Healing in Human Dermal Fibroblast](https://pubmed.ncbi.nlm.nih.gov/40363772/) Squalane · Molecules, 2025
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Fractional microneedle radiofrequency with the application of vitamin C, E, and ferulic acid serum for neck skin rejuvenation: a prospective, double-blinded, split-neck, placebo-controlled trial](https://pubmed.ncbi.nlm.nih.gov/40464749/) Ferulic acid · The Journal of Dermatological Treatment, 2025
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Depth-dependent hydration dynamics in human skin: Vehicle-controlled efficacy assessment of a functional 10% urea plus NMF moisturizer by near-infrared confocal spectroscopic imaging (KOSIM IR) and capacitance method complemented by volunteer perception](https://pubmed.ncbi.nlm.nih.gov/35034387/) Moisturizing factors nmf · Skin Research and Technology, 2022
- [Effect of hydroxypropyl-β-cyclodextrin in fluid and semi-solid submicron emulsions on physiological skin parameters during regular in vivo application](https://pubmed.ncbi.nlm.nih.gov/33236374/) Cyclodextrin · International Journal of Cosmetic Science, 2021
- [Effects of Investigational Moisturizers on the Skin Barrier and Microbiome following Exposure to Environmental Aggressors: A Randomized Clinical Trial and Ex Vivo Analysis](https://pubmed.ncbi.nlm.nih.gov/37763018/) Yeast extract · Journal of Clinical Medicine, 2023
- [Design and in vivo evaluation of emulgel formulations including green tea extract and rose oil](https://pubmed.ncbi.nlm.nih.gov/24451077/) Rosa damascena oil flower, The rose essential oil · Acta Pharmaceutica, 2013
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Emulgels Containing Perilla frutescens Seed Oil, Moringa oleifera Seed Oil, and Mixed Seed Oil: Microemulsion and Safety Assessment](https://pubmed.ncbi.nlm.nih.gov/35745923/) Moringa oleifera seed oil · Polymers, 2022
- [Assessment of the efficacy and safety of a new complex skin cream in Asian women: A controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/28512843/) Hydroxyresveratrol · Journal of Cosmetic Dermatology, 2017
- [A randomized controlled trial to compare the effectiveness and safety of adsorbent lotion containing tapioca starch, spent grain wax, Butyrospermum parkii extract, argania spinosa kernel oil, aloe barbadensis, rosehip oil, and allantoin with a low-potency topical corticosteroid in the treatment of intertrigo](https://pubmed.ncbi.nlm.nih.gov/33811776/) Shea butter · Journal of Cosmetic Dermatology, 2022
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Prospective randomized double-blind comparative study of topical acetyl zingerone with tetrahexyldecyl ascorbate versus tetrahexyldecyl ascorbate alone on facial photoaging](https://pubmed.ncbi.nlm.nih.gov/38525606/) Tetrahexyldecyl ascorbate · Journal of Cosmetic Dermatology, 2024
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
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- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
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- [Clinical Efficacy of a Flavo-Proxylane Topical Regimen Pre- and Post-ultrasound Procedure for Subjects Undergoing Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist Therapy](https://pubmed.ncbi.nlm.nih.gov/41781778/) Hydroxypropyl tetrahydropyrantriol · Dermatology and Therapy, 2026
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## The brands

- British skincare: [Medik8](https://lovi.care/skincare/sa/brands/medik8)
- French skincare: [Lancôme](https://lovi.care/skincare/sa/brands/lancome)

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- [The Ordinary vs Lancôme](https://lovi.care/skincare/sa/compare/the-ordinary-vs-lancome)
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- [COSRX vs Medik8](https://lovi.care/skincare/sa/compare/cosrx-vs-medik8)
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- [CeraVe vs Medik8](https://lovi.care/skincare/sa/compare/cerave-vs-medik8)
- [CeraVe vs Lancôme](https://lovi.care/skincare/sa/compare/cerave-vs-lancome)
- [La Roche-Posay vs Medik8](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-medik8)
- [La Roche-Posay vs Lancôme](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-lancome)
- [Dr. Althea vs Medik8](https://lovi.care/skincare/sa/compare/dr-althea-vs-medik8)
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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/medik8-vs-lancome
- United Kingdom: https://lovi.care/skincare/uk/compare/medik8-vs-lancome
- Ireland: https://lovi.care/skincare/ie/compare/medik8-vs-lancome
- Germany: https://lovi.care/skincare/de/compare/medik8-vs-lancome
- France: https://lovi.care/skincare/fr/compare/medik8-vs-lancome
- Italy: https://lovi.care/skincare/it/compare/medik8-vs-lancome
- Netherlands: https://lovi.care/skincare/nl/compare/medik8-vs-lancome
- Spain: https://lovi.care/skincare/es/compare/medik8-vs-lancome
- Canada: https://lovi.care/skincare/ca/compare/medik8-vs-lancome
- Australia: https://lovi.care/skincare/au/compare/medik8-vs-lancome
- Singapore: https://lovi.care/skincare/sg/compare/medik8-vs-lancome
- Saudi Arabia: https://lovi.care/skincare/sa/compare/medik8-vs-lancome (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/medik8-vs-lancome