# Medicube vs Neutrogena

Page: https://lovi.care/skincare/sa/compare/medicube-vs-neutrogena

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Medicube and Neutrogena are established skincare brands offering distinct approaches to daily wellness. The South Korean line, founded in 2016, features curated moisturizers, [serums](https://lovi.care/skincare/sa/ingredients/serum), toners, and masks with [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide), [collagen](https://lovi.care/skincare/sa/ingredients/collagen), and [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid) to suit oily and acne-prone skin by balancing sebum and hydration. Meanwhile, the American line, founded in 1930, provides thoughtfully formulated moisturizers, sunscreens, cleansers, and toners utilizing [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin), hyaluronic acid, and [dimethicone](https://lovi.care/skincare/sa/ingredients/dimethicone) to best serve mature skin and skin with dark spots. Ultimately, both brands differ through their specific ingredient synergies and targeted formulations, allowing individuals to select solutions tailored precisely to their unique complexion needs.

Medicube is a Korean skincare brand founded in 2016 and owned by APR Corp..

[medicubereviews.co.uk](https://medicubereviews.co.uk/medicube/story/) [glossy.co](https://www.glossy.co/beauty/medicubes-founder-on-the-products-and-people-that-fueled-the-k-beauty-brands-booming-year/)

Neutrogena is an American skincare brand founded in 1930 and owned by Kimberly-Clark Corporation since 2026.

[investor.kimberly-clark.com](https://www.investor.kimberly-clark.com/news-releases/news-release-details/kimberly-clark-completes-acquisition-kenvue-creating-preeminent) [en.wikipedia.org](https://en.wikipedia.org/wiki/Neutrogena) [investors.kenvue.com](https://investors.kenvue.com/financial-news/news-details/2025/Kimberly-Clark-to-Acquire-Kenvue-Creating-a-32-Billion-Global-Health-and-Wellness-Leader/default.aspx)

This page compares some of the most popular Medicube and Neutrogena products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg98908b170e).

### Popular Medicube vs Neutrogena products

#### Medicube

- [Zero Pore Pad](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [PDRN Pink Peptide Serum](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-peptide-serum/for/mature-skin) — High fit — [SAR 41.77 at Amazon](https://www.amazon.sa/dp/B0DBF65JYY?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Collagen Jelly Cream](https://lovi.care/skincare/sa/p/medicube/collagen-jelly-cream/for/mature-skin) — Superior fit — [SAR 48.10 at Amazon](https://www.amazon.sa/dp/B0F4PNBXLZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Collagen Night Wrapping Mask](https://lovi.care/skincare/sa/p/medicube/collagen-night-wrapping-mask/for/dry-skin) — High fit
- [PDRN Pink Collagen Gel Mask](https://lovi.care/skincare/sa/p/medicube/pdrn-pink-collagen-gel-mask/for/dry-sensitive-skin) — High fit — [SAR 68.00 at Amazon](https://www.amazon.sa/dp/B0DT6Y6QC5?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [DEEP VITA-C CAPSULE CREAM](https://lovi.care/skincare/sa/p/medicube/deep-vita-c-capsule-cream/for/sensitive-skin) — Average fit — [SAR 64.14 at Amazon](https://www.amazon.sa/dp/B0D2Z3GGCY?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [TRIPLE COLLAGEN CREAM](https://lovi.care/skincare/sa/p/medicube/triple-collagen-cream/for/mature-skin) — Average fit — [SAR 55.25 at Amazon](https://www.amazon.sa/dp/B0DLG3S62C?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Zero Foam Cleanser](https://lovi.care/skincare/sa/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [SAR 40.90 at Amazon](https://www.amazon.sa/dp/B09C1B7BH5?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### Neutrogena

- [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/sensitive-skin) — Average fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [SAR 51.99 at Amazon](https://www.amazon.sa/dp/B082PFY9S7?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [SAR 99.99 at Amazon](https://www.amazon.sa/dp/B0DFWH7XPZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Ultra Gentle Daily Cleanser](https://lovi.care/skincare/sa/p/neutrogena/ultra-gentle-daily-cleanser/for/mature-skin) — Superior fit — [SAR 86.93 at Amazon](https://www.amazon.sa/dp/B085S7FZTM?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Rapid Wrinkle Repair Regenerating Cream](https://lovi.care/skincare/sa/p/neutrogena/rapid-wrinkle-repair-regenerating-cream/for/mature-skin) — High fit — [SAR 178.55 at Amazon](https://www.amazon.sa/dp/B01HOHBS6G?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/dark-spots) — Superior fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Retinol Regenerating Cream](https://lovi.care/skincare/sa/p/neutrogena/retinol-regenerating-cream/for/mature-skin) — Average fit
- [COLLAGEN BANK Moisturizer](https://lovi.care/skincare/sa/p/neutrogena/collagen-bank-moisturizer/for/dry-skin) — Average fit — [SAR 131.00 at Amazon](https://www.amazon.sa/dp/B0DX2V5F69?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## People Say

Medicube

Neutrogena

- Hydration and Moisture Mostly Mentioned Mostly Mentioned “skin feels bouncier and hydrated — Medicube PDRN Pink Peptide Serum” “glass skin — Medicube PDRN Pink Collagen Gel Mask” “Skin looked plumper and radiant — Neutrogena HYDRO BOOST WATER CREAM” “It also hydrates my skin. This cream has been so easy to add to my routine. — Neutrogena Retinol Regenerating Cream”
- Skin Smoothing and Texture Improvement Often Mentioned Sometimes Noted “gives my skin a smooth, glass-like finish — Medicube Zero Pore Pad” “skin feels smoother — Medicube PDRN Pink Peptide Serum” “Skin is looking smoother — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “I can see a difference in my forehead wrinkles. — Neutrogena Retinol Regenerating Cream”
- Lightweight and Non-Greasy Rarely Noted Mostly Mentioned “Absorbs instantly without sticky residue — Neutrogena Hydro Boost Water Gel” “absorbs instantly — Neutrogena COLLAGEN BANK Moisturizer” “Absorbs into skin without residue. — Neutrogena Hydro Boost Hyaluronic Acid Serum” “finish isn't sticky — Medicube Red Succinic Acid Peeling Pad”
- Gentle Cleansing and Sensitive Skin Rarely Noted Mostly Mentioned “leaves skin soft and balanced — Neutrogena Ultra Gentle Daily Cleanser” “love that it has no scent — Neutrogena Ultra Gentle Daily Cleanser” “calms my acne prone skin — Neutrogena Ultra Gentle Daily Cleanser” “Did not cause any irritation — Medicube Red Foam Cleanser”
- Soothing and Cooling Sensation Often Mentioned Rarely Noted “feels amazing and cooling — Medicube Zero Pore Blackhead Mud Mask” “refreshing sensation — Medicube PDRN Pink Collagen Gel Mask” “calming the skin — Medicube Red Succinic Acid Peeling Pad” “Feels amazing and cold on the skin — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- Glow and Radiance Often Mentioned Rarely Noted “gave me instant glass skin — Medicube Collagen Jelly Cream” “woke up with glowing skin — Medicube Collagen Night Wrapping Mask” “Dark spots go away faster — Medicube Deep Vita C Pad” “Gave me a glass-skin glow — Neutrogena Hydro Boost Hydrating Hydrogel Mask”
- Packaging and Quantity Concerns Often Mentioned Often Mentioned “tube is tiny for the price — Medicube Collagen Night Wrapping Mask” “price is steep — Medicube PDRN Pink Collagen Gel Mask” “Jar is too small for the price — Neutrogena Hydro Boost Water Gel” “Runs out quickly — Neutrogena HYDRO BOOST WATER CREAM”
- Breakouts and Skin Irritation Often Mentioned Often Mentioned “caused redness and sensitivity — Medicube Zero Pore Pad” “woke up with whiteheads — Medicube Collagen Night Wrapping Mask” “Made my face very red — Neutrogena HYDRO BOOST WATER CREAM” “Burning sensation — Neutrogena Rapid Wrinkle Repair Regenerating Cream”
- Strong Fragrance and Scent Issues Often Mentioned Sometimes Noted “Smell is too overpowering and lingering — Neutrogena Hydro Boost Water Gel” “Scent is so off-putting — Neutrogena Rapid Wrinkle Repair Regenerating Cream” “has a weird plastic smell — Neutrogena Ultra Gentle Daily Cleanser” “slightly fishy smell — Medicube PDRN Pink Peptide Serum”

### Medicube vs Neutrogena routines for dry skin

#### Medicube-focused routine

- Cleanser: [Zero Foam Cleanser](https://lovi.care/skincare/sa/p/medicube/zero-foam-cleanser/for/dry-skin) — Superior fit — [SAR 40.90 at Amazon](https://www.amazon.sa/dp/B09C1B7BH5?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/sa/p/medicube/triple-collagen-toner/for/dry-skin) — High fit — [SAR 50.00 at Amazon](https://www.amazon.sa/dp/B085VS2J3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/sa/p/medicube/age-r-booster-gel/for/dry-skin) — Superior fit — [SAR 117.99 at Amazon](https://www.amazon.sa/dp/B0H4MHPRLG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [SAR 65.11 at Amazon](https://www.amazon.sa/dp/B084Q16G8D?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad/for/dry-skin) — Average fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [One Day Exosome Shot 2000](https://lovi.care/skincare/sa/p/medicube/one-day-exosome-shot-2000/for/dry-skin) — High fit — [SAR 34.00 at Amazon](https://www.amazon.sa/dp/B0D16L5F2M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Deep Peptide Radiance Mask](https://lovi.care/skincare/sa/p/medicube/deep-peptide-radiance-mask/for/dry-skin) — High fit — [SAR 120.88 at Amazon](https://www.amazon.sa/dp/B0HGBQSTDY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/dry-skin) — Average fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/dry-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/dry-skin) — Superior fit — [SAR 150.91 at Amazon](https://www.amazon.sa/dp/B08937VD6Z?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/dry-skin) — Average fit — [SAR 115.51 at Amazon](https://www.amazon.sa/dp/B08L88LZ4V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [HYDRO BOOST WATER CREAM](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-cream/for/dry-skin) — Superior fit — [SAR 99.99 at Amazon](https://www.amazon.sa/dp/B0DFWH7XPZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/dry-skin) — Warning fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/dry-skin) — Low fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Hydro Boost Hydrating Hydrogel Mask](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hydrating-hydrogel-mask/for/dry-skin) — High fit — [SAR 74.18 at Amazon](https://www.amazon.sa/dp/B076V9PK87?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · SAR 698.98 · 86% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B09C1B7BH5&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0H4MHPRLG&Quantity.3=1&ASIN.4=B09D7QJP1M&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B0D16L5F2M&Quantity.7=1&ASIN.8=B01KTJXVI4&Quantity.8=1&ASIN.9=B0HGBQSTDY&Quantity.9=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 854.76 · 69% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B08937VD6Z&Quantity.3=1&ASIN.4=B08L88LZ4V&Quantity.4=1&ASIN.5=B0DFWH7XPZ&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B01KTJXVI4&Quantity.8=1&ASIN.9=B076V9PK87&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sa/skin/dry-skin)

### Medicube vs Neutrogena routines for oily skin

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/sa/p/medicube/red-foam-cleanser/for/oily-skin) — High fit — [SAR 35.61 at Amazon](https://www.amazon.sa/dp/B073ZBXSJD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/sa/p/medicube/triple-collagen-toner/for/oily-skin) — High fit — [SAR 50.00 at Amazon](https://www.amazon.sa/dp/B085VS2J3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/sa/p/medicube/age-r-booster-gel/for/oily-skin) — High fit — [SAR 117.99 at Amazon](https://www.amazon.sa/dp/B0H4MHPRLG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad/for/oily-skin) — Superior fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/sa/p/medicube/zero-pore-blackhead-mud-mask/for/oily-skin) — Average fit — [SAR 87.59 at Amazon](https://www.amazon.sa/dp/B0H6GFKP6V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/oily-skin) — Caution fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/oily-skin) — Average fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost+ Niacinamide Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-niacinamide-serum/for/oily-skin) — High fit — [SAR 80.82 at Amazon](https://www.amazon.sa/dp/B0F9LJWVXY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Clear Face Liquid Lotion Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/clear-face-liquid-lotion-sunscreen/for/oily-skin) — Superior fit — [SAR 115.51 at Amazon](https://www.amazon.sa/dp/B08L88LZ4V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/oily-skin) — Average fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/oily-skin) — Average fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/oily-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Clear Pore Cleanser/Mask](https://lovi.care/skincare/sa/p/neutrogena/clear-pore-cleanser-mask/for/oily-skin) — Average fit — [SAR 103.58 at Amazon](https://www.amazon.sa/dp/B000NSIGE6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · SAR 806.40 · 88% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B073ZBXSJD&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0H4MHPRLG&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B001VMJSCW&Quantity.7=1&ASIN.8=B0H6GFKP6V&Quantity.8=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 811.22 · 70% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B0F9LJWVXY&Quantity.3=1&ASIN.4=B08L88LZ4V&Quantity.4=1&ASIN.5=B000NWAOHE&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B000NSIGE6&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/oily-skin)

### Medicube vs Neutrogena routines for combination skin

#### Medicube-focused routine

- Cleanser: [Red Foam Cleanser](https://lovi.care/skincare/sa/p/medicube/red-foam-cleanser/for/combination-skin) — High fit — [SAR 35.61 at Amazon](https://www.amazon.sa/dp/B073ZBXSJD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Triple Collagen Toner](https://lovi.care/skincare/sa/p/medicube/triple-collagen-toner/for/combination-skin) — High fit — [SAR 50.00 at Amazon](https://www.amazon.sa/dp/B085VS2J3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [AGE-R Booster Gel](https://lovi.care/skincare/sa/p/medicube/age-r-booster-gel/for/combination-skin) — High fit — [SAR 117.99 at Amazon](https://www.amazon.sa/dp/B0H4MHPRLG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Zero Pore Pad](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad/for/combination-skin) — Superior fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Zero Pore Blackhead Mud Mask](https://lovi.care/skincare/sa/p/medicube/zero-pore-blackhead-mud-mask/for/combination-skin) — Average fit — [SAR 87.59 at Amazon](https://www.amazon.sa/dp/B0H6GFKP6V?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Neutrogena-focused routine

- Cleanser: [Hydro Boost Water Gel](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-water-gel/for/combination-skin) — Low fit — [SAR 17.19 at Amazon](https://www.amazon.sa/dp/B07MTX97N7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Alcohol-Free Toner](https://lovi.care/skincare/sa/p/neutrogena/alcohol-free-toner/for/combination-skin) — Average fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B0BNC5ZF3T?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Hydro Boost Hyaluronic Acid Serum](https://lovi.care/skincare/sa/p/neutrogena/hydro-boost-hyaluronic-acid-serum/for/combination-skin) — High fit — [SAR 150.91 at Amazon](https://www.amazon.sa/dp/B08937VD6Z?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Ultra Sheer Dry-Touch Sunscreen](https://lovi.care/skincare/sa/p/neutrogena/ultra-sheer-dry-touch-sunscreen/for/combination-skin) — Superior fit — [SAR 51.99 at Amazon](https://www.amazon.sa/dp/B082PFY9S7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Oil-Free Eye Makeup Remover](https://lovi.care/skincare/sa/p/neutrogena/oil-free-eye-makeup-remover/for/combination-skin) — High fit — [SAR 69.93 at Amazon](https://www.amazon.sa/dp/B000NWAOHE?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Blackhead Eliminating Cleansing Toner](https://lovi.care/skincare/sa/p/neutrogena/blackhead-eliminating-cleansing-toner/for/combination-skin) — Average fit — [SAR 72.68 at Amazon](https://www.amazon.sa/dp/B07WDTB9X7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Stubborn Marks PM Treatment](https://lovi.care/skincare/sa/p/neutrogena/stubborn-marks-pm-treatment/for/combination-skin) — High fit — [SAR 97.00 at Amazon](https://www.amazon.sa/dp/B08CHDVN12?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Clear Pore Cleanser/Mask](https://lovi.care/skincare/sa/p/neutrogena/clear-pore-cleanser-mask/for/combination-skin) — Average fit — [SAR 103.58 at Amazon](https://www.amazon.sa/dp/B000NSIGE6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Medicube routine · SAR 806.40 · 88% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B073ZBXSJD&Quantity.1=1&ASIN.2=B085VS2J3T&Quantity.2=1&ASIN.3=B0H4MHPRLG&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B001VMJSCW&Quantity.7=1&ASIN.8=B0H6GFKP6V&Quantity.8=1&AssociateTag=lovisa02-21) [Buy Neutrogena routine · SAR 817.79 · 74% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07MTX97N7&Quantity.1=1&ASIN.2=B0BNC5ZF3T&Quantity.2=1&ASIN.3=B08937VD6Z&Quantity.3=1&ASIN.4=B082PFY9S7&Quantity.4=1&ASIN.5=B000NWAOHE&Quantity.5=1&ASIN.6=B07WDTB9X7&Quantity.6=1&ASIN.7=B08CHDVN12&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B000NSIGE6&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/combination-skin)

## Questions and answers

### Medicube or Neutrogena: which is better?

Medicube is a better fit for dry skin, dry sensitive skin, oily skin, combination skin, and oily acne-prone skin, while both brands are an equal fit for acne-prone skin, mature skin, and skin with dark spots. Medicube features key ingredients like [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) and [hyaluronic acid](https://lovi.care/skincare/sa/ingredients/hyaluronic-acid), which help reduce pigmentation and improve skin hydration.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/)

### What is the difference between Medicube and Neutrogena?

Medicube fits dry, oily, combination, sensitive, dry sensitive, and oily acne-prone skin with High routines, while Neutrogena fits these skin types with Average routines. Both brands have High routine fits for acne-prone skin, mature skin, and skin with dark spots. Medicube is better for glow, radiance, and soothing sensations, whereas Neutrogena is better for being lightweight and non-greasy, gentle on sensitive skin, and avoiding strong fragrances.

### Medicube or Neutrogena for dry skin?

For dry skin, Medicube has a High routine fit while Neutrogena has an Average routine fit. Medicube offers dedicated hydration options like the Triple [Collagen](https://lovi.care/skincare/sa/ingredients/collagen) Toner and AGE-R Booster Gel that help improve skin moisture.

### Medicube or Neutrogena: which cleanser is better?

Both Medicube and Neutrogena offer highly rated cleansers, such as the Medicube Zero Foam Cleanser and the Neutrogena Ultra Gentle Daily Cleanser, which both achieve high fit levels for many skin types. Reviewers indicate that Neutrogena tends to do better for gentle cleansing and sensitive skin.

### Which is more affordable, Medicube or Neutrogena?

Reviewers of the products on this page note packaging and value concerns for both Medicube and Neutrogena.

### Medicube or Neutrogena: which brand has more products containing fragrance?

Neutrogena has more products containing fragrance, with 4 fragranced products on its page compared to 2 for Medicube.

### Medicube or Neutrogena: which brand offers better results for skin glow and radiance?

Medicube offers better results for skin glow and radiance compared to Neutrogena. The products on this page help improve radiance through key ingredients like niacinamide, which is supported by studies on reducing pigmentation.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Medicube or Neutrogena: which brand provides a lighter and less greasy feel for moisturizers?

Neutrogena provides a lighter and less greasy feel for moisturizers compared to Medicube. Reviewers frequently mention Neutrogena moisturizers as lightweight and non-greasy.

### Medicube or Neutrogena for oily skin?

For oily skin, Medicube has a High routine fit while Neutrogena has an Average routine fit. Medicube is focused on oily skin, oily acne-prone skin, and combination skin, and the products on this page help deliver deep hydration and smoothing.

### Medicube or Neutrogena: which moisturizer is better?

Medicube is generally better suited for moisturizers across various skin types, as Lovi rates its routines high for dry, oily, combination, sensitive, and dry sensitive skin compared to Neutrogena's average fit for those skin types. Both brands offer moisturizers featuring hyaluronic acid to help improve skin hydration.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Medicube or Neutrogena for sensitive skin?

Medicube is a better fit for sensitive skin, offering a High routine fit compared to Neutrogena's Average fit. The products on this page help provide gentle hydration with key ingredients like hyaluronic acid and niacinamide.

[Journal of Pharmacy & Pharmaceutical Sciences, 2015](https://pubmed.ncbi.nlm.nih.gov/25877441/) [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Medicube or Neutrogena for acne-prone skin?

Both Medicube and Neutrogena have a High fit for acne-prone skin with the products on this page. Medicube uses key ingredients like [salicylic acid](https://lovi.care/skincare/sa/ingredients/salicylic-acid) to help clear pores, while Neutrogena offers options like its Daily Facial Moisturizer to help manage breakouts.

## Research behind their key ingredients

- [Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin](https://pubmed.ncbi.nlm.nih.gov/10692106/) Retinol · The Journal of Investigative Dermatology, 2000
- [Hyaluronic acid and wound healing](https://pubmed.ncbi.nlm.nih.gov/25877441/) Sodium hyaluronate · Journal of Pharmacy & Pharmaceutical Sciences, 2015
- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Sodium hyaluronate · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Final report on the safety assessment of Benzyl Alcohol, Benzoic Acid, and Sodium Benzoate](https://pubmed.ncbi.nlm.nih.gov/11766131/) Benzyl alcohol · International Journal of Toxicology, 2001
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Vitamin b5, Panthenol · American Journal of Clinical Dermatology, 2002
- [The Effect of Aloe Vera Clinical Trials on Prevention and Healing of Skin Wound: A Systematic Review](https://pubmed.ncbi.nlm.nih.gov/30666070/) Aloe barbadensis leaf extract · Iranian Journal of Medical Sciences, 2019
- [Efficacy of combined treatment with human adipose tissue stem cell-derived exosome-containing solution and microneedling for facial skin aging: A 12-week prospective, randomized, split-face study](https://pubmed.ncbi.nlm.nih.gov/37377400/) Exosome cica · Journal of Cosmetic Dermatology, 2023
- [Improvement of naturally aged skin with vitamin A (retinol)](https://pubmed.ncbi.nlm.nih.gov/17515510/) Retinol · Archives of Dermatology, 2007
- [Final report on the safety assessment of BHT(1)](https://pubmed.ncbi.nlm.nih.gov/12396675/) Bht · International Journal of Toxicology, 2002
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Vitamin c derivatives · Experimental Dermatology, 2003
- [Topical application of glycolic acid suppresses the UVB induced IL-6, IL-8, MCP-1 and COX-2 inflammation by modulating NF-κB signaling pathway in keratinocytes and mice skin](https://pubmed.ncbi.nlm.nih.gov/28330776/) Aha · Journal of Dermatological Science, 2017
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Collagen Supplements for Aging and Wrinkles: A Paradigm Shift in the Fields of Dermatology and Cosmetics](https://pubmed.ncbi.nlm.nih.gov/35223163/) Collagen, Water-soluble collagen · Dermatology Practical & Conceptual, 2022
- [Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin](https://pubmed.ncbi.nlm.nih.gov/18492182/) Palmitoyl pentapeptide-4 · International Journal of Cosmetic Science, 2005
- [Molecular basis of retinol anti-ageing properties in naturally aged human skin in vivo](https://pubmed.ncbi.nlm.nih.gov/27261203/) Retinol · International Journal of Cosmetic Science, 2017
- [Tea tree oil reduces histamine-induced skin inflammation](https://pubmed.ncbi.nlm.nih.gov/12452873/) Tree · The British Journal of Dermatology, 2002
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Retinol, Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) Ascorbyl glucoside · Journal of Periodontology, 2009
- [Apigenin inhibits UVA-induced cytotoxicity in vitro and prevents signs of skin aging in vivo](https://pubmed.ncbi.nlm.nih.gov/27279007/) Chamomilla recutita flower extract matricaria flower extract · International Journal of Molecular Medicine, 2016
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica extract, Madecassoside · Indian Journal of Pharmaceutical Sciences, 2016
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [Use of Collagen in Cosmetic Products](https://pubmed.ncbi.nlm.nih.gov/38534748/) Collagen, Water-soluble collagen · Current Issues in Molecular Biology, 2024
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice, Aloe barbadensis leaf extract · Clinical Pharmacology, 2018
- [Effect of Camellia japonica oil on human type I procollagen production and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/17386986/) Camellia japonica flower extract · Journal of Ethnopharmacology, 2007
- [Topical benzoyl peroxide for acne](https://pubmed.ncbi.nlm.nih.gov/32175593/) Benzoyl peroxide · The Cochrane Database of Systematic Reviews, 2020
- [Sacha Inchi Oil (Plukenetia volubilis L.), effect on adherence of Staphylococus aureus to human skin explant and keratinocytes in vitro](https://pubmed.ncbi.nlm.nih.gov/26087228/) Plukenetia volubilis seed oil · Journal of Ethnopharmacology, 2015
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Benzoyl peroxide treatment decreases Cutibacterium acnes in shoulder surgery, from skin incision until wound closure](https://pubmed.ncbi.nlm.nih.gov/33545336/) Benzoyl peroxide · Journal of Shoulder and Elbow Surgery, 2021
- [Efficacy and Safety of a Fixed-Dose Clindamycin Phosphate 1.2%, Benzoyl Peroxide 3.1%, and Adapalene 0.15% Gel for Moderate-to-Severe Acne: A Randomized Phase II Study of the First Triple-Combination Drug](https://pubmed.ncbi.nlm.nih.gov/34674160/) Benzoyl peroxide · American Journal of Clinical Dermatology, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-acetyl glucosamine](https://pubmed.ncbi.nlm.nih.gov/17348991/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic Dermatology, 2007
- [Reduction in the appearance of facial hyperpigmentation after use of moisturizers with a combination of topical niacinamide and N-acetyl glucosamine: results of a randomized, double-blind, vehicle-controlled trial](https://pubmed.ncbi.nlm.nih.gov/19845667/) Acetyl glucosamine, Neoglucosamine · The British Journal of Dermatology, 2010
- [The anti-wrinkle efficacy of argireline, a synthetic hexapeptide, in Chinese subjects: a randomized, placebo-controlled study](https://pubmed.ncbi.nlm.nih.gov/23417317/) Acetyl hexapeptide-8 · American Journal of Clinical Dermatology, 2013
- [Protective effects of Camellia japonica flower extract against urban air pollutants](https://pubmed.ncbi.nlm.nih.gov/30691451/) Camellia japonica flower extract · BMC Complementary and Alternative Medicine, 2019
- [Quaternized carboxymethyl chitosan/organic montmorillonite nanocomposite as a novel cosmetic ingredient against skin aging](https://pubmed.ncbi.nlm.nih.gov/28732847/) Bentonite · Carbohydrate Polymers, 2017
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid, Microclear technology · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Vitamin b5, Panthenol · The Journal of Dermatological Treatment, 2017
- [Development and photoprotective effect of a sunscreen containing the antioxidants Spirulina and dimethylmethoxy chromanol on sun-induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28341613/) Dimethylmethoxy chromanol · European Journal of Pharmaceutical Sciences, 2017
- [Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study](https://pubmed.ncbi.nlm.nih.gov/30548170/) Glycolic acid · Journal of Cosmetic Dermatology, 2019
- [Phytosphingosine enhances moisture level in human skin barrier through stimulation of the filaggrin biosynthesis and degradation leading to NMF formation](https://pubmed.ncbi.nlm.nih.gov/28936777/) Hydration complex · Archives of Dermatological Research, 2017
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Hydrolyzed Collagen Induces an Anti-Inflammatory Response That Induces Proliferation of Skin Fibroblast and Keratinocytes](https://pubmed.ncbi.nlm.nih.gov/36501011/) Collagen extract · Nutrients, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Sunscreens and Cosmetic Formulations Containing Ascorbyl Tetraisopalmitate and Rice Peptides for the Improvement of Skin Photoaging: A Double-blind, Randomized Placebo-controlled Clinical Study](https://pubmed.ncbi.nlm.nih.gov/33529350/) Vitamin c derivatives · Photochemistry and Photobiology, 2021
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Glycolic acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [High molecular compounds (polysaccharides and proanthocyanidins) from Hamamelis virginiana bark: influence on human skin keratinocyte proliferation and differentiation and influence on irritated skin](https://pubmed.ncbi.nlm.nih.gov/11684194/) Witch hazel extract · Phytochemistry, 2001
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica extract, Madecassoside, Centella asiatica leaf extract · Molecules, 2023
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Gluconolactone · The Australasian Journal of Dermatology, 1992
- [Anti-Wrinkle Efficacy of Cross-Linked Hyaluronic Acid-Based Microneedle Patch with Acetyl Hexapeptide-8 and Epidermal Growth Factor on Korean Skin](https://pubmed.ncbi.nlm.nih.gov/33911590/) Acetyl hexapeptide-8 · Annals of Dermatology, 2019
- [Anti-inflammatory activity of parthenolide-depleted Feverfew (Tanacetum parthenium)](https://pubmed.ncbi.nlm.nih.gov/19112586/) Chrysanthemum parthenium flower leaf stem juice · Inflammopharmacology, 2009
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid, Microclear technology · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine](https://pubmed.ncbi.nlm.nih.gov/34284096/) Sophora angustifolia root extract, Sophora flavescens root extract · European Journal of Pharmaceutical Sciences, 2021
- [Efficacy and Tolerability of a Skin Brightening/Anti-Aging Cosmeceutical Containing Retinol 0.5%, Niacinamide, Hexylresorcinol, and Resveratrol](https://pubmed.ncbi.nlm.nih.gov/27391637/) Hexylresorcinol · Journal of Drugs in Dermatology, 2016
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid, Microclear technology · Journal of Drugs in Dermatology, 2023
- [Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin](https://pubmed.ncbi.nlm.nih.gov/26805418/) Lifting peptide · Journal of the European Academy of Dermatology and Venereology, 2016
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Preparation and evaluation of benzalkonium chloride hand sanitizer as a potential alternative for alcohol-based hand gels](https://pubmed.ncbi.nlm.nih.gov/34408542/) Benzalkonium chloride · Saudi Pharmaceutical Journal, 2021
- [Retaining Skin Barrier Function Properties of the Stratum Corneum with Components of the Natural Moisturizing Factor-A Randomized, Placebo-Controlled Double-Blind In Vivo Study](https://pubmed.ncbi.nlm.nih.gov/33809557/) Hydration complex · Molecules, 2021
- [Superior even skin tone and anti-ageing benefit of a combination of 4-hexylresorcinol and niacinamide](https://pubmed.ncbi.nlm.nih.gov/34958693/) Hexylresorcinol · International Journal of Cosmetic Science, 2022
- [Efficacy and safety of microencapsulated benzoyl peroxide and microencapsulated tretinoin for the treatment of acne vulgaris: Results from two phase 3 double-blind, randomized, vehicle-controlled studies](https://pubmed.ncbi.nlm.nih.gov/37356627/) Benzoyl peroxide · Journal of the American Academy of Dermatology, 2023
- [Stretchable skin hydrating PVB patches with controlled pores' size and shape for deliberate evening primrose oil spreading, transport and release](https://pubmed.ncbi.nlm.nih.gov/35929319/) Oenothera biennis flower extract · Biomaterials Advances, 2022
- [Effects of 1,3-propanediol associated, or not, with butylene glycol and/or glycerol on skin hydration and skin barrier function](https://pubmed.ncbi.nlm.nih.gov/37699769/) Propanediol · International Journal of Cosmetic Science, 2024
- [Efficacy and tolerability of the investigational topical cream SD-101 (6% allantoin) in patients with epidermolysis bullosa: a phase 3, randomized, double-blind, vehicle-controlled trial (ESSENCE study)](https://pubmed.ncbi.nlm.nih.gov/32576219/) Allantoin · Orphanet Journal of Rare Diseases, 2020
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [Challenging the safety and efficacy of topically applied chlorogenic acid, apigenin, kaempferol, and naringenin by HET-CAM, HPLC-TBARS-EVSC, and laser Doppler flowmetry](https://pubmed.ncbi.nlm.nih.gov/38831914/) Grapefruit extract · Frontiers in Chemistry, 2024
- [Antiacne and antiblotch activities of a formulated combination of Aloe barbadensis leaf powder, Garcinia mangostana peel extract, and Camellia sinensis leaf extract](https://pubmed.ncbi.nlm.nih.gov/31239743/) Camellia sinensis leaf extract · Clinical, Cosmetic and Investigational Dermatology, 2019
- [New clinical approach in facial mild-moderate acne: Re-stabilization of skin microbiota balance with a topical biotechnological phytocomplex](https://pubmed.ncbi.nlm.nih.gov/39205505/) Succinic acid · Journal of Cosmetic Dermatology, 2024
- [The efficacy study of the combination of tripeptide-10-citrulline and acetyl hexapeptide-3. A prospective, randomized controlled study](https://pubmed.ncbi.nlm.nih.gov/28150423/) Acetyl hexapeptide-8 · Journal of Cosmetic Dermatology, 2017
- [Safety assessment of cyclomethicone, cyclotetrasiloxane, cyclopentasiloxane, cyclohexasiloxane, and cycloheptasiloxane](https://pubmed.ncbi.nlm.nih.gov/22247236/) Cyclopentasiloxane · International Journal of Toxicology, 2011
- [Is benzyl alcohol a significant contact sensitizer?](https://pubmed.ncbi.nlm.nih.gov/35080274/) Benzyl alcohol · Journal of the European Academy of Dermatology and Venereology, 2022
- [Evaluation of moisturizing and irritation potential of sacha inchi oil](https://pubmed.ncbi.nlm.nih.gov/31441999/) Plukenetia volubilis seed oil · Journal of Cosmetic Dermatology, 2020
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Effect of a botanical cleansing lotion on skin sebum and erythema of the face: A randomized controlled blinded half-side comparison](https://pubmed.ncbi.nlm.nih.gov/30022595/) Willow bark extract · Journal of Cosmetic Dermatology, 2019
- [Anti-Inflammatory Effect of a Novel Topical Herbal Composition (VEL-091604) Consisting of Gentian Root, Licorice Root and Willow Bark Extract](https://pubmed.ncbi.nlm.nih.gov/30690691/) Willow bark extract · Planta Medica, 2019
- [An evaluation of the effect of a topical product containing salicin on the visible signs of human skin aging](https://pubmed.ncbi.nlm.nih.gov/20883292/) Willow bark extract · Journal of Cosmetic Dermatology, 2010
- [A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/32390309/) Lauric acid · Dermatologic Therapy, 2020
- [The synergistic effect of retinyl propionate and hydroxypinacolone retinoate on skin aging](https://pubmed.ncbi.nlm.nih.gov/36762391/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2023
- [Administration of skin care regimens containing β-glucan for skin recovery after fractional laser therapy: A split-face, double-blinded, vehicle-controlled study](https://pubmed.ncbi.nlm.nih.gov/33128496/) Beta-glucan · Journal of Cosmetic Dermatology, 2021
- [Parthenolide-depleted Feverfew (Tanacetum parthenium) protects skin from UV irradiation and external aggression](https://pubmed.ncbi.nlm.nih.gov/18071724/) Chrysanthemum parthenium flower leaf stem juice · Archives of Dermatological Research, 2008
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Effect of seasonal and geographical differences on skin and effect of treatment with an osmoprotectant: Sorbitol](https://pubmed.ncbi.nlm.nih.gov/23752031/) Sorbitol · Journal of Cosmetic Science, 2013
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Solid lipid nanoparticles bearing oxybenzone: in-vitro and in-vivo evaluation](https://pubmed.ncbi.nlm.nih.gov/19622017/) Oxybenzone, Oxybenzone-free formula · Journal of Microencapsulation, 2010
- [Nanostructured Lipid Carrier for Topical Application of N-Acetyl Glucosamine](https://pubmed.ncbi.nlm.nih.gov/28101465/) Acetyl glucosamine, Neoglucosamine · Advanced Pharmaceutical Bulletin, 2016
- [Gene expression profile of human follicle dermal papilla cells in response to Camellia japonica phytoplacenta extract](https://pubmed.ncbi.nlm.nih.gov/33410284/) Camellia japonica flower extract · FEBS Open Bio, 2021
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Axillary hyperhidrosis. Local treatment with aluminium-chloride hexahydrate 25% in absolute ethanol with and without supplementary treatment with triethanolamine](https://pubmed.ncbi.nlm.nih.gov/2449022/) Triethanolamine · Acta Dermato-venereologica, 1988
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Oxybenzone-free formula · International Journal of Pharmaceutics, 2019
- [Comparison of topical purslane & topical 0.1% triamcinolone acetonide in the management of oral lichen planus - a double blinded clinical trial](https://pubmed.ncbi.nlm.nih.gov/37726676/) Portulaca oleracea extract · BMC Oral Health, 2023
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Anti-inflammatory and skin-hydrating properties of a dietary supplement and topical formulations containing oligomeric proanthocyanidins](https://pubmed.ncbi.nlm.nih.gov/17035721/) Grape seed extract · Skin Pharmacology and Physiology, 2007
- [Clinical study of Asian skin changes after application of a sunscreen formulation containing grape seed extract](https://pubmed.ncbi.nlm.nih.gov/35403355/) Grape seed extract · Journal of Cosmetic Dermatology, 2022
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Rates of allergic sensitization and irritation to oxybenzone-containing sunscreen products: a quantitative meta-analysis of 64 exaggerated use studies](https://pubmed.ncbi.nlm.nih.gov/18717962/) Helioplex technology, Helioplex · Photodermatology, Photoimmunology & Photomedicine, 2008
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [A controlled, three-part trial to investigate the barrier function and skin hydration properties of six skin protectants](https://pubmed.ncbi.nlm.nih.gov/16439809/) Dimethicone · Ostomy/wound Management, 2005
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [The anti wrinkle efficacy of synthetic hexapeptide (Argireline) in Chinese Subjects](https://pubmed.ncbi.nlm.nih.gov/23607739/) Acetyl hexapeptide-8 · Journal of Cosmetic and Laser Therapy, 2013
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Propanediol · Molecules, 2021
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Vitamin b5, Panthenol · Journal of Cosmetic Dermatology, 2025
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Avobenzone · European Journal of Pharmaceutical Sciences, 2023
- [A new formula for a mild body cleanser: sodium laureth sulphate supplemented with sodium laureth carboxylate and lauryl glucoside](https://pubmed.ncbi.nlm.nih.gov/24617572/) Lauryl glucoside · International Journal of Cosmetic Science, 2014
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Cucumber (Cucumis sativus L.) with heterologous poly-γ-glutamic acid has skin moisturizing, whitening and anti-wrinkle effects](https://pubmed.ncbi.nlm.nih.gov/38336313/) Cucumis sativus fruit extract · International Journal of Biological Macromolecules, 2024
- [Prospective, randomized, double-blind clinical study of split-body comparison of topical hydroquinone and hexylresorcinol for skin pigment appearance](https://pubmed.ncbi.nlm.nih.gov/36502500/) Hexylresorcinol · Archives of Dermatological Research, 2023
- [Instrumental, clinical and subjective evaluation of the efficacy of a cosmetic treatment for home use](https://pubmed.ncbi.nlm.nih.gov/30040516/) Acetyl glucosamine, Neoglucosamine · Journal of Cosmetic and Laser Therapy, 2019
- [Functional properties and skin care effects of sodium trehalose sulfate](https://pubmed.ncbi.nlm.nih.gov/38606717/) Trehalose · Skin Research and Technology, 2024
- [Composition characterization and clinical efficacy study of a salmon egg extract](https://pubmed.ncbi.nlm.nih.gov/23738607/) Salmon egg extract · International Journal of Cosmetic Science, 2013
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Ethanolamines permeate slowly across human skin ex vivo, but cause severe skin irritation at low concentrations](https://pubmed.ncbi.nlm.nih.gov/31435711/) Ethanolamine · Archives of Toxicology, 2019
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/23545907/) Citric acid · Journal of Drugs in Dermatology, 2013
- [Portulaca oleracea extract relieves skin barrier damage induced by increased photosensitivity after GA peeling](https://pubmed.ncbi.nlm.nih.gov/35920724/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2022
- [Anti-Aging Efficacy of Low-Molecular-Weight Polydeoxyribonucleotide Derived from Paeonia lactiflora](https://pubmed.ncbi.nlm.nih.gov/41516097/) Sodium dna, Pdrn polydeoxyribonucleotide · International Journal of Molecular Sciences, 2025
- [Polydeoxyribonucleotide-spermidine nanoparticles: Preparation, characterization, and verification of skin anti-aging efficacy](https://pubmed.ncbi.nlm.nih.gov/40840755/) Sodium dna · International Journal of Biological Macromolecules, 2025
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Efficacy of Topical Hydroxypinacolone Retinoate-Peptide Product Versus Fractional CO2 Laser in Facial Aging](https://pubmed.ncbi.nlm.nih.gov/39394831/) Hydroxypinacolone retinoate · Journal of Cosmetic Dermatology, 2025
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
- [A Randomized Controlled Trial of the Genistein Plus Bakuchiol and Vitamins (GEN+) Product for Male Facial Skin: Effects on Skin Appearance and Properties](https://pubmed.ncbi.nlm.nih.gov/41562471/) Bakuchiol · Skin Research and Technology, 2026
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Low-temperature extracted Portulaca oleracea L. as a functional ingredient in facial masks for photorejuvenation of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41182319/) Portulaca oleracea extract · Cutaneous and Ocular Toxicology, 2025
- [The Therapeutic Effects of a Bentonite-Based Facial Mask With Alcea sulphurea Extract on Acne Severity and Patient Experience: Add-On Randomized Controlled Clinical Trial](https://pubmed.ncbi.nlm.nih.gov/41347526/) Bentonite · Journal of Cosmetic Dermatology, 2025
- [Split-face evaluation: Gluconolactone plus oxybrasion versus gluconolactone plus microneedling. The effects on skin parameters](https://pubmed.ncbi.nlm.nih.gov/37357656/) Gluconolactone · Skin Research and Technology, 2023
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Homosalate, Octisalate, Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Acetyl Dipeptide-31 Amide: A Novel Cosmetic Anti-Inflammatory Peptide That Demonstrates Anti-Aging, Firming, and Lifting Benefits](https://pubmed.ncbi.nlm.nih.gov/39761149/) Acetyl dipeptide-31 amide · Journal of Drugs in Dermatology, 2025
- [Natural Moisturizing Factor-Enriched Formulations Compared to a Ceramide-Based Cream](https://pubmed.ncbi.nlm.nih.gov/38443132/) Hydration complex · Journal of Drugs in Dermatology, 2024
- [Synergistic combination: Developing a natural carrier-free assembled gel through hydrogen bond reconstruction strategy for efficient skin photo-damage restoration](https://pubmed.ncbi.nlm.nih.gov/41129958/) Sodium pca · Biomaterials Advances, 2026
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Impact of dermal emulsions containing diacyl phospholipids, mono acyl phospholipids, sodium lauryl ether sulfate and polysorbate 80 in combination with UVA irradiation on human skin physiology in vivo: A pilot study](https://pubmed.ncbi.nlm.nih.gov/42617898/) Sodium laureth sulfate · International Journal of Pharmaceutics, 2026

## The brands

- Korean skincare: [Medicube](https://lovi.care/skincare/sa/brands/medicube)
- American skincare: [Neutrogena](https://lovi.care/skincare/sa/brands/neutrogena)

## More comparisons

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## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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