# ISDIN vs VR

Page: https://lovi.care/skincare/sa/compare/isdin-vs-vr

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

ISDIN and VR are established skincare lines that offer thoughtful options for daily routines. The Spanish brand is known for advanced moisturizers, sunscreens, [serums](https://lovi.care/skincare/sa/ingredients/serum), and eye products crafted with key ingredients for sensitive skin and acne-prone skin, while the other is appreciated for the sensory pleasure of its moisturizers and the considered design of its formulas suited best for combination, sensitive, and dry skin. Both creators provide standout solutions, including Fusion [Water](https://lovi.care/skincare/sa/ingredients/water), Eryfotona Actinica, and K-Ox Eyes from the Puig-owned line, alongside the [PDRN](https://lovi.care/skincare/sa/ingredients/pdrn) CREAM from the alternative. They differ mainly in their precise focuses and target skin types, helping users maintain a healthy complexion.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

This page compares some of the most popular ISDIN and VR products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg1b59aa5b5a).

### Popular ISDIN vs VR products

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/sa/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [SAR 429.81 at Amazon](https://www.amazon.sa/dp/B07RXS4FQM?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/sa/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B00Z72U6JQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/sa/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [SAR 241.20 at Amazon](https://www.amazon.sa/dp/B01BMLQ4JQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/sa/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/sa/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [SAR 848.48 at Amazon](https://www.amazon.sa/dp/B01BMLQ086?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/sa/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/sa/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [SAR 310.30 at Amazon](https://www.amazon.sa/dp/B0BD9DK6SC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### VR

- [PDRN CREAM](https://lovi.care/skincare/sa/p/vr/pdrn-cream/for/sensitive-skin) — High fit

## Questions and answers

### ISDIN or VR: which is better?

ISDIN is the better choice on this page because it offers a much wider variety of products with Superior or High Lovi fit levels across many skin types. VR features only a single product, [PDRN](https://lovi.care/skincare/sa/ingredients/pdrn) CREAM, which has a High fit level for sensitive skin but only Average or Low fit levels for other skin types.

### What is the difference between ISDIN and VR?

ISDIN offers a larger selection of eight products on this page across sun care, moisturizers, [serums](https://lovi.care/skincare/sa/ingredients/serum), and eye care, while VR provides just one moisturizer, PDRN CREAM. Additionally, while every VR product on this page is fragrance-free, three of ISDIN's eight products list no fragrance and the rest contain it.

### ISDIN or VR: which moisturizer is better?

When comparing moisturizers, ISDIN offers a wider variety for different needs, with options like Hyaluronic Concentrate reaching a High fit for sensitive and acne-prone skin, whereas VR features PDRN CREAM with a High fit specifically for sensitive skin.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Which is more affordable, ISDIN or VR?

When it comes to affordability, the products on this page for ISDIN have a high price point according to reviewers, while pricing details for VR are not mentioned.

### Which causes fewer breakouts, ISDIN or VR?

VR does not feature products on this page formulated specifically for acne-prone skin, while ISDIN offers several items like Eryfotona Actinica and Fusion [Water](https://lovi.care/skincare/sa/ingredients/water) that achieve a High Lovi fit for acne-prone skin.

### Which brand was founded earlier, ISDIN or VR?

ISDIN was founded earlier in 1975 in Spain, whereas VR was founded in 2018.

### How many products do ISDIN and VR each have on this page?

ISDIN has 8 products on this page, while VR has 1 product listed.

### Do both ISDIN and VR products contain fragrance?

Not all ISDIN products contain fragrance, as three out of eight products on this page list no fragrance. In contrast, every VR product on this page lists no fragrance in its ingredients.

## Research behind their key ingredients

- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) 5-ceramide complex · Skin Pharmacology and Physiology, 2022
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Effects of Moringa oleifera Seed Oil on Cultured Human Sebocytes In Vitro and Comparison with Other Oil Types](https://pubmed.ncbi.nlm.nih.gov/37373478/) Moringa oleifera seed oil · International Journal of Molecular Sciences, 2023
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [Monocentric, Vehicle-Controlled, Double-Blind Study to Assess the Short- and Long-Term Effects of a Ceramide NP C15-Containing Emollient on the Skin Microbiome and the Skin Barrier Function in Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/41758783/) 5-ceramide complex · Skin Pharmacology and Physiology, 2026

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/sa/brands/isdin)
- Skincare: [VR](https://lovi.care/skincare/sa/brands/vr)

## More comparisons

- [SKIN1004 vs ISDIN](https://lovi.care/skincare/sa/compare/skin1004-vs-isdin)
- [SKIN1004 vs VR](https://lovi.care/skincare/sa/compare/skin1004-vs-vr)
- [Anua vs ISDIN](https://lovi.care/skincare/sa/compare/anua-vs-isdin)
- [Anua vs VR](https://lovi.care/skincare/sa/compare/anua-vs-vr)
- [Medicube vs ISDIN](https://lovi.care/skincare/sa/compare/medicube-vs-isdin)
- [Medicube vs VR](https://lovi.care/skincare/sa/compare/medicube-vs-vr)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/sa/compare/the-ordinary-vs-isdin)
- [The Ordinary vs VR](https://lovi.care/skincare/sa/compare/the-ordinary-vs-vr)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs VR](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-vr)
- [COSRX vs ISDIN](https://lovi.care/skincare/sa/compare/cosrx-vs-isdin)
- [COSRX vs VR](https://lovi.care/skincare/sa/compare/cosrx-vs-vr)
- [CeraVe vs ISDIN](https://lovi.care/skincare/sa/compare/cerave-vs-isdin)
- [CeraVe vs VR](https://lovi.care/skincare/sa/compare/cerave-vs-vr)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs VR](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-vr)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/sa/compare/dr-althea-vs-isdin)
- [Dr. Althea vs VR](https://lovi.care/skincare/sa/compare/dr-althea-vs-vr)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/sa/compare/some-by-mi-vs-isdin)
- [Some By Mi vs VR](https://lovi.care/skincare/sa/compare/some-by-mi-vs-vr)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-vr
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-vr
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-vr
- Germany: https://lovi.care/skincare/de/compare/isdin-vs-vr
- France: https://lovi.care/skincare/fr/compare/isdin-vs-vr
- Italy: https://lovi.care/skincare/it/compare/isdin-vs-vr
- Netherlands: https://lovi.care/skincare/nl/compare/isdin-vs-vr
- Spain: https://lovi.care/skincare/es/compare/isdin-vs-vr
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-vr
- Australia: https://lovi.care/skincare/au/compare/isdin-vs-vr
- Singapore: https://lovi.care/skincare/sg/compare/isdin-vs-vr
- Saudi Arabia: https://lovi.care/skincare/sa/compare/isdin-vs-vr (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/isdin-vs-vr