# ISDIN vs SK-II

Page: https://lovi.care/skincare/sa/compare/isdin-vs-sk-ii

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

ISDIN and SK-II are established skincare names, with the Spanish brand founded in 1975 and the Japanese brand originating in 1980. The former offers advanced moisturizers, sunscreens, [serums](https://lovi.care/skincare/sa/ingredients/serum), and eye products that suit sensitive skin and acne-prone skin best, while the latter is known for nourishing moisturizers, targeted serums, restorative masks, clarifying toners, and pitera-powered formulations that suit dry sensitive skin and combination skin best. Both collections address specific concerns like dark spots and mature skin, yet they differ in their foundational approach and regional heritage.

ISDIN is a Spanish skincare brand founded in 1975 and owned by Puig.

[puig.com](https://www.puig.com/en/newsroom/new-chapter-for-Isdin-Puig-to-assume-full-ownership/) [beautymatter.com](https://beautymatter.com/articles/puig-to-take-full-ownership-of-isdin-in-1-39-billion-deal) [uploads.puig.com](https://uploads.puig.com/uploads/Puig_NP_Sept_14_EN_fc21e2f47a.pdf)

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

This page compares some of the most popular ISDIN and SK-II products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgf12d99597c).

### Popular ISDIN vs SK-II products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Skinpower Advanced Cream](https://lovi.care/skincare/sa/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit — [SAR 1,289.20 at Amazon](https://www.amazon.sa/dp/B0CFW488TZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Ultraura Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Spot Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### ISDIN

- [Eryfotona Actinica](https://lovi.care/skincare/sa/p/isdin/eryfotona-actinica/for/mature-skin) — Superior fit — [SAR 429.81 at Amazon](https://www.amazon.sa/dp/B07RXS4FQM?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Fusion Water](https://lovi.care/skincare/sa/p/isdin/fusion-water/for/dry-sensitive-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B00Z72U6JQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [K-Ox Eyes](https://lovi.care/skincare/sa/p/isdin/k-ox-eyes/for/dry-skin) — High fit — [SAR 241.20 at Amazon](https://www.amazon.sa/dp/B01BMLQ4JQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Hyaluronic Concentrate](https://lovi.care/skincare/sa/p/isdin/hyaluronic-concentrate/for/sensitive-skin) — High fit
- [Hyaluronic Moisture](https://lovi.care/skincare/sa/p/isdin/hyaluronic-moisture/for/dry-sensitive-skin) — Average fit
- [Flavo-C Serum](https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/sensitive-skin) — High fit — [SAR 848.48 at Amazon](https://www.amazon.sa/dp/B01BMLQ086?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Uradin Lotion 10](https://lovi.care/skincare/sa/p/isdin/uradin-lotion-10/for/dry-skin) — High fit
- [Retinal Intense Serum](https://lovi.care/skincare/sa/p/isdin/retinal-intense-serum/for/acne-prone-skin) — High fit — [SAR 310.30 at Amazon](https://www.amazon.sa/dp/B0BD9DK6SC?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## People Say

ISDIN

SK-II

- Lightweight and fluid texture Mostly Mentioned Mostly Mentioned “absorbs instantly — ISDIN Eryfotona Actinica” “ultra-light fluid product, which makes it super easy to apply — ISDIN Fusion Water” “drinks right into the skin — SK-II Facial Treatment Essence” “pores became miraculously invisible — SK-II Facial Treatment Mask”
- Hydrating and smoothing Mostly Mentioned Mostly Mentioned “Improved moisture and texture — ISDIN Hyaluronic Moisture” “skin looks smooth and healthy — ISDIN K-Ox Eyes” “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream”
- Brightens and evens skin tone Rarely Noted Mostly Mentioned “skin feels soft as butter — SK-II Facial Treatment Essence” “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask” “My hyperpigmentation has lightened and skin looks more even, even shines more. — ISDIN Flavo-C Serum”
- Gentle on sensitive skin Often Mentioned Rarely Noted “Sensitive/reactive skin tolerates — ISDIN Hyaluronic Moisture” “no excessive exfoliation — ISDIN Retinal Intense Serum” “doesn't sting eyes — ISDIN Eryfotona Actinica” “Great for sensitive — SK-II Genoptics Spot Essence”
- Makeup compatibility Often Mentioned Rarely Noted “acts like a primer — ISDIN Eryfotona Actinica” “My skin felt sooo hydrated and looks so plump and dewey. — ISDIN Fusion Water” “Great under makeup — ISDIN Hyaluronic Concentrate” “Dissolves waterproof mascara, melts stubborn makeup, removes sunscreen easily. — SK-II Facial Treatment Cleansing Oil”
- High price point Often Mentioned Mostly Mentioned “very expensive — ISDIN Eryfotona Actinica” “My only wish is that ISDIN would make this product in a bigger size bottle. — ISDIN Fusion Water” “high cost — ISDIN K-Ox Eyes” “way too expensive — SK-II Facial Treatment Essence”
- Strong fragrance and scent issues Often Mentioned Often Mentioned “smell is overpowering — ISDIN Eryfotona Actinica” “lingering headache inducing effect — ISDIN K-Ox Eyes” “smells like dirty feet — SK-II Facial Treatment Essence” “smells slightly like saliva — SK-II Facial Treatment Mask”
- Lack of results Rarely Noted Often Mentioned “don't see result — ISDIN K-Ox Eyes” “no noticeable changes yet — ISDIN Retinal Intense Serum” “did absolutely nothing — SK-II Facial Treatment Essence”
- Skin irritation and breakouts Sometimes Noted Often Mentioned “mild redness or irritation — ISDIN K-Ox Eyes” “Not hydrating enough in winter — ISDIN Hyaluronic Concentrate” “I think the serum is too strong for my face as it has burned and left very rough and a peeling face. — ISDIN Flavo-C Serum” “caused tiny red bumps — SK-II Facial Treatment Essence”

### ISDIN vs SK-II routines for dry skin

#### ISDIN-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/sa/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — [SAR 48.00 at Amazon](https://www.amazon.sa/dp/B0BTPGPK7H?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Fusion Water](https://lovi.care/skincare/sa/p/isdin/fusion-water/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B00Z72U6JQ?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [SAR 65.11 at Amazon](https://www.amazon.sa/dp/B084Q16G8D?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/sa/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [SAR 72.64 at Amazon](https://www.amazon.sa/dp/B0F625GKWW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/dry-skin) — Average fit — [SAR 848.48 at Amazon](https://www.amazon.sa/dp/B01BMLQ086?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/sa/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [SAR 234.73 at Amazon](https://www.amazon.sa/dp/B0FMFZRJTD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/dry-skin) — Caution fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · SAR 1,771.26 · 92% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B0BTPGPK7H&Quantity.2=1&ASIN.3=B00Z72U6JQ&Quantity.3=1&ASIN.4=B084Q16G8D&Quantity.4=1&ASIN.5=B0F625GKWW&Quantity.5=1&ASIN.6=B01BMLQ086&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B0FMFZRJTD&Quantity.8=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 2,157.75 · 83% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B000H723LU&Quantity.2=1&ASIN.3=B09D7QJP1M&Quantity.3=1&ASIN.4=B084M1R6RH&Quantity.4=1&ASIN.5=B072C3MCDH&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B078MQP5ZF&Quantity.8=1&AssociateTag=lovisa02-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sa/skin/dry-skin)

### ISDIN vs SK-II routines for oily skin

#### ISDIN-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — [SAR 39.70 at Amazon](https://www.amazon.sa/dp/B01CLTKI4A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/sa/p/isdin/eryfotona-actinica/for/oily-skin) — High fit — [SAR 429.81 at Amazon](https://www.amazon.sa/dp/B07RXS4FQM?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/sa/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [SAR 187.00 at Amazon](https://www.amazon.sa/dp/B0GFGP11BW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/oily-skin) — High fit — [SAR 848.48 at Amazon](https://www.amazon.sa/dp/B01BMLQ086?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/oily-skin) — Average fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/oily-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · SAR 2,326.11 · 93% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B07RXS4FQM&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0GFGP11BW&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 1,935.93 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/oily-skin)

### ISDIN vs SK-II routines for combination skin

#### ISDIN-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion (with Birch Sap)](https://lovi.care/skincare/sa/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — [SAR 39.70 at Amazon](https://www.amazon.sa/dp/B01CLTKI4A?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Eryfotona Actinica](https://lovi.care/skincare/sa/p/isdin/eryfotona-actinica/for/combination-skin) — High fit — [SAR 429.81 at Amazon](https://www.amazon.sa/dp/B07RXS4FQM?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Flavo-C Serum](https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/combination-skin) — High fit — [SAR 848.48 at Amazon](https://www.amazon.sa/dp/B01BMLQ086?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/combination-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/combination-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/combination-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy ISDIN routine · SAR 2,312.92 · 93% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B01CLTKI4A&Quantity.3=1&ASIN.4=B07RXS4FQM&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B01BMLQ086&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 2,044.94 · 90% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/combination-skin)

## Questions and answers

### ISDIN or SK-II: which is better?

ISDIN is better suited overall for sensitive and acne-prone skin, while SK-II tends to be preferred for brightening and evening skin tone. Lovi rates ISDIN as Superior across all main skin types on the products on this page, whereas SK-II receives a mix of Superior and High ratings.

### What is the difference between ISDIN and SK-II?

ISDIN tends to be gentler on sensitive skin and offers makeup-friendly sunscreens, while SK-II does better at brightening and evening skin tone. Lovi rates the routine fit for sensitive skin as Superior for ISDIN and High for SK-II.

### ISDIN or SK-II for dry skin?

For dry skin, Lovi rates ISDIN as a Superior fit and SK-II as a High fit. The products on this page from ISDIN are known for lightweight moisturizers, while SK-II features fragrance-free formulas.

### ISDIN or SK-II: which moisturizer is better?

When it comes to moisturizers, SK-II brightens and evens skin tone better, while the products on this page from ISDIN are sometimes noted for having a strong fragrance.

### Which is more affordable, ISDIN or SK-II?

Both ISDIN and SK-II are high-end brands, but reviewers on the products on this page often mention a high price point for ISDIN.

### Which brand has a stronger fragrance, ISDIN or SK-II?

ISDIN has a stronger fragrance, with five of the products on this page listing fragrance ingredients. In contrast, every SK-II product on this page lists no fragrance.

### ISDIN or SK-II for oily skin?

For oily skin, Lovi finds ISDIN has a Superior routine fit and SK-II has a High routine fit. Reviewers often mention that ISDIN offers ultralight sunscreens and lightweight moisturizers that may help with shine, while SK-II features key ingredients like Pitera across the products on this page.

### ISDIN or SK-II for sensitive skin?

For sensitive skin, Lovi gives ISDIN a Superior fit level and SK-II a High fit level.

### ISDIN or SK-II for acne-prone skin?

For acne-prone skin, Lovi rates both ISDIN and SK-II as having a Superior routine fit. ISDIN helps with its acne-focused [serum](https://lovi.care/skincare/sa/ingredients/serum) options, while SK-II products on this page list no fragrance.

### ISDIN or SK-II for dry sensitive skin?

For dry sensitive skin, Lovi finds that both ISDIN and SK-II are a Superior fit. Reviewers note that ISDIN helps with makeup compatibility and sensitive skin, while SK-II features fragrance-free formulas with Pitera.

### ISDIN or SK-II for mature skin?

For mature skin, Lovi rates ISDIN as Superior and SK-II as High. Reviewers note that the products on this page for SK-II brighten and even skin tone better.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Skin delivery of epigallocatechin-3-gallate (EGCG) and hyaluronic acid loaded nano-transfersomes for antioxidant and anti-aging effects in UV radiation induced skin damage](https://pubmed.ncbi.nlm.nih.gov/28155509/) Antioxidants · Drug Delivery, 2017
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Sodium hyaluronate, Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Antiaging efficacy of melatonin-based day and night creams: a randomized, split-face, assessor-blinded proof-of-concept trial](https://pubmed.ncbi.nlm.nih.gov/29416368/) Melatonin · Clinical, Cosmetic and Investigational Dermatology, 2018
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Concentrated glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate · Urologia Internationalis, 2019
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [Comparison of methods for assessing photoprotection against ultraviolet A in vivo](https://pubmed.ncbi.nlm.nih.gov/3819071/) Butyl methoxydibenzoylmethane · Journal of the American Academy of Dermatology, 1987
- [Using ordered mesoporous silica SBA-15 to limit cutaneous penetration and transdermal permeation of organic UV filters](https://pubmed.ncbi.nlm.nih.gov/31437563/) Butyl methoxydibenzoylmethane · International Journal of Pharmaceutics, 2019
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [Enhancing Photoprotection and Mitigating Ex Vivo Stratum Corneum Oxidative Stress: A Multifunctional Strategy Combining Rosmarinic Acid with UVB Filters](https://pubmed.ncbi.nlm.nih.gov/40227214/) Octocrylene · Antioxidants, 2025
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [TiO2-embedded mesoporous silica with lower porosity is beneficial to adsorb the pollutants and retard UV filter absorption: A possible application for outdoor skin protection](https://pubmed.ncbi.nlm.nih.gov/36455708/) Butyl methoxydibenzoylmethane · European Journal of Pharmaceutical Sciences, 2023
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Ginkgo biloba leaves extract's cosmeceutical evaluation: a preliminary assessments on human volunteers towards achieving improved skin condition and rejuvenation](https://pubmed.ncbi.nlm.nih.gov/37074796/) Ginkgo biloba leaf extract · Drug Development and Industrial Pharmacy, 2023
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Ethylhexyl salicylate · Archives of Dermatological Research, 2024
- [The clinical efficacy of a new emulsion for acne and conspicuous facial pore amelioration](https://pubmed.ncbi.nlm.nih.gov/38140770/) Lens esculenta seed extract · Journal of Cosmetic Dermatology, 2024
- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
- [Treatment with Ascorbyl Glucoside-Arginine Complex Ameliorates Solar Lentigos](https://pubmed.ncbi.nlm.nih.gov/39769217/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · International Journal of Molecular Sciences, 2024
- [Retrospective Review of Dermal Safety Studies of Organic Sunscreens](https://pubmed.ncbi.nlm.nih.gov/40911743/) Ethylhexyl salicylate · Journal of Drugs in Dermatology, 2025
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026
- [Mechanistic understanding and peptide ingredient screening for type III collagen via biological knowledge graph and molecular docking](https://pubmed.ncbi.nlm.nih.gov/42683869/) Palmitoyl tripeptide-1, Palmitoyl tetrapeptide-7 · International Journal of Cosmetic Science, 2026
- [Prospective, Randomized, Double-Blind Assessment of Supramolecular Bakuchiol and Terminalia Chebula Extract for Facial Photoaging in Chinese Sensitive Skin Population](https://pubmed.ncbi.nlm.nih.gov/41424674/) Bakuchiol · Health Science Reports, 2025
- [The Effectiveness of Galactomyces Ferment Filtrate, Dexpanthenol, and Centella Asiatica Combination Serum in the Treatment of Post-Acne Hyperpigmentation in Subjects with Skin of Color](https://pubmed.ncbi.nlm.nih.gov/33938432/) Galactomyces ferment filtrate, Sk-ii pitera concentrate, Galactomyces ferment filtrate pitera ferment filtrate · Skinmed, 2021
- [Clinical Efficacy of Topical Ascorbic Acid 2-Glucoside in Enhancing Outcomes of Laser Gingival Depigmentation: A Randomized Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42147661/) Ascorbyl glucoside · Cureus, 2026

## The brands

- Spanish skincare: [ISDIN](https://lovi.care/skincare/sa/brands/isdin)
- Japanese skincare: [SK-II](https://lovi.care/skincare/sa/brands/sk-ii)

## More comparisons

- [SKIN1004 vs ISDIN](https://lovi.care/skincare/sa/compare/skin1004-vs-isdin)
- [SKIN1004 vs SK-II](https://lovi.care/skincare/sa/compare/skin1004-vs-sk-ii)
- [Anua vs ISDIN](https://lovi.care/skincare/sa/compare/anua-vs-isdin)
- [Anua vs SK-II](https://lovi.care/skincare/sa/compare/anua-vs-sk-ii)
- [Medicube vs ISDIN](https://lovi.care/skincare/sa/compare/medicube-vs-isdin)
- [Medicube vs SK-II](https://lovi.care/skincare/sa/compare/medicube-vs-sk-ii)
- [The Ordinary vs ISDIN](https://lovi.care/skincare/sa/compare/the-ordinary-vs-isdin)
- [The Ordinary vs SK-II](https://lovi.care/skincare/sa/compare/the-ordinary-vs-sk-ii)
- [Beauty of Joseon vs ISDIN](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-isdin)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-sk-ii)
- [COSRX vs ISDIN](https://lovi.care/skincare/sa/compare/cosrx-vs-isdin)
- [COSRX vs SK-II](https://lovi.care/skincare/sa/compare/cosrx-vs-sk-ii)
- [CeraVe vs ISDIN](https://lovi.care/skincare/sa/compare/cerave-vs-isdin)
- [CeraVe vs SK-II](https://lovi.care/skincare/sa/compare/cerave-vs-sk-ii)
- [La Roche-Posay vs ISDIN](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-isdin)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-sk-ii)
- [Dr. Althea vs ISDIN](https://lovi.care/skincare/sa/compare/dr-althea-vs-isdin)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/sa/compare/dr-althea-vs-sk-ii)
- [Some By Mi vs ISDIN](https://lovi.care/skincare/sa/compare/some-by-mi-vs-isdin)
- [Some By Mi vs SK-II](https://lovi.care/skincare/sa/compare/some-by-mi-vs-sk-ii)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/isdin-vs-sk-ii
- United Kingdom: https://lovi.care/skincare/uk/compare/isdin-vs-sk-ii
- Ireland: https://lovi.care/skincare/ie/compare/isdin-vs-sk-ii
- Germany: https://lovi.care/skincare/de/compare/isdin-vs-sk-ii
- France: https://lovi.care/skincare/fr/compare/isdin-vs-sk-ii
- Italy: https://lovi.care/skincare/it/compare/isdin-vs-sk-ii
- Netherlands: https://lovi.care/skincare/nl/compare/isdin-vs-sk-ii
- Spain: https://lovi.care/skincare/es/compare/isdin-vs-sk-ii
- Canada: https://lovi.care/skincare/ca/compare/isdin-vs-sk-ii
- Australia: https://lovi.care/skincare/au/compare/isdin-vs-sk-ii
- Singapore: https://lovi.care/skincare/sg/compare/isdin-vs-sk-ii
- Saudi Arabia: https://lovi.care/skincare/sa/compare/isdin-vs-sk-ii (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/isdin-vs-sk-ii