# Dr. Althea vs Natura Bissé

Page: https://lovi.care/skincare/sa/compare/dr-althea-vs-natura-bisse

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Dr. Althea and Natura Bissé are distinct skincare companies offering thoughtfully crafted moisturizers, cleansers, makeup removers, and [serums](https://lovi.care/skincare/sa/ingredients/serum). The Korean brand, founded in 2014, is known for gentle formulas featuring key ingredients that suit acne-prone and dry skin best, whereas the Spanish brand, founded in 1979, is celebrated for luxurious treatments and advanced formulas that nourish mature, dry, and sensitive skin. While both labels provide reliable care to restore balance, they differ in their origins, ingredient focuses, and primary skin-type suitability.

Dr. Althea is a Korean skincare brand founded in 2014 and owned by The Pure Lab Co., Ltd..

[doctoraltheaglobal.com](https://doctoraltheaglobal.com/) [doctoralthea.co.kr](https://doctoralthea.co.kr/shopinfo/company.html)

Natura Bissé is a Spanish skincare brand founded in 1979 and owned by Natura Bissé International, S.A..

[naturabisse.com](https://www.naturabisse.com/int/en/our-story.html) [tracxn.com](https://tracxn.com/d/accelerator-incubator/ushopal/__yjGH7DKhQGNWnINKarEuFce6tilrPzGJv0PnASFLfpg)

This page compares some of the most popular Dr. Althea and Natura Bissé products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pg983939a048).

### Popular Dr. Althea vs Natura Bissé products

#### Natura Bissé

- [Diamond Extreme](https://lovi.care/skincare/sa/p/natura-bisse/diamond-extreme/for/mature-skin) — Superior fit — [SAR 1,034.77 at Amazon](https://www.amazon.sa/dp/B0BKLRMKZV?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

#### Dr. Althea

- [345 Relief Cream](https://lovi.care/skincare/sa/p/dr-althea/345-relief-cream/for/acne-prone-skin) — Superior fit — [SAR 59.90 at Amazon](https://www.amazon.sa/dp/B0FKGJYFC8?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Barrier Cream](https://lovi.care/skincare/sa/p/dr-althea/barrier-cream/for/mature-skin) — High fit — [SAR 83.00 at Amazon](https://www.amazon.sa/dp/B0GPPRTD32?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Pure Grinding Cleansing Balm](https://lovi.care/skincare/sa/p/dr-althea/pure-grinding-cleansing-balm/for/dry-skin) — High fit — [SAR 59.43 at Amazon](https://www.amazon.sa/dp/B0DXPFMBYX?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Amino Acid Gentle Bubble Cleanser](https://lovi.care/skincare/sa/p/dr-althea/amino-acid-gentle-bubble-cleanser/for/oily-skin) — Superior fit — [SAR 40.34 at Amazon](https://www.amazon.sa/dp/B0CLGGP723?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Amino Gel Cleanser](https://lovi.care/skincare/sa/p/dr-althea/amino-gel-cleanser/for/mature-skin) — Average fit — [SAR 40.34 at Amazon](https://www.amazon.sa/dp/B0CLGGP723?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Vitamin C Boosting Serum](https://lovi.care/skincare/sa/p/dr-althea/vitamin-c-boosting-serum/for/mature-skin) — High fit — [SAR 50.03 at Amazon](https://www.amazon.sa/dp/B0CW99ZRWB?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## Questions and answers

### Dr. Althea or Natura Bissé: which is better?

Dr. Althea is a better fit for a wider variety of skin types and budgets, offering Superior Lovi fits for acne-prone, oily, and dry skin with fragrance-free formulas. In contrast, Natura Bissé features a single luxury option on this page, Diamond Extreme, which has a High Lovi fit for mature skin but contains fragrance.

### What is the difference between Dr. Althea and Natura Bissé?

Dr. Althea offers a wide range of fragrance-free products on this page like the 345 Relief Cream and Amino Acid Gentle Bubble Cleanser, while Natura Bissé features just one luxury moisturizer, Diamond Extreme, which contains fragrance. Lovi rates Dr. Althea as having Superior fit for acne-prone, dry, and oily skin types, whereas Natura Bissé provides a Superior fit specifically for mature skin.

### Dr. Althea or Natura Bissé: which moisturizer is better?

For acne-prone skin and oily acne-prone skin, Dr. Althea's 345 Relief Cream is rated Superior by Lovi, while Natura Bissé's Diamond Extreme is only rated Average.

### Which is more affordable, Dr. Althea or Natura Bissé?

The provided page facts do not contain pricing information, so it is not possible to determine whether Dr. Althea or Natura Bissé is more affordable.

### Which causes fewer breakouts, Dr. Althea or Natura Bissé?

Dr. Althea has a Superior Lovi fit for acne-prone skin with products like the 345 Relief Cream and Amino Acid Gentle Bubble Cleanser, whereas Natura Bissé's Diamond Extreme has only an Average fit for acne-prone skin.

### Which brand has more products that are fragrance-free, Dr. Althea or Natura Bissé?

Dr. Althea has more products that are fragrance-free, as every product on its page lists no fragrance in its ingredients.

### How do the founding years and countries of origin compare between Dr. Althea and Natura Bissé?

Dr. Althea was founded in 2014 in South Korea, while Natura Bissé was founded earlier in 1979 in Spain.

### What are the main criticisms or negative reviews reported for Dr. Althea skincare products?

Reviewers note that Dr. Althea products on this page sometimes involve scent and irritation issues, can occasionally cause breakouts, and may be weak on waterproof makeup.

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Niacinamide · The British Journal of Dermatology, 2002
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol · American Journal of Clinical Dermatology, 2002
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Tocopherol, Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Moisturizing and Antiinflammatory Properties of Cosmetic Formulations Containing Centella asiatica Extract](https://pubmed.ncbi.nlm.nih.gov/27168678/) Centella asiatica, Centella asiatica extract · Indian Journal of Pharmaceutical Sciences, 2016
- [Topical Application of Centella asiatica in Wound Healing: Recent Insights into Mechanisms and Clinical Efficacy](https://pubmed.ncbi.nlm.nih.gov/39458583/) Centella asiatica · Pharmaceutics, 2024
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramide · Scientific Reports, 2022
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Clinical, biometric and structural evaluation of the long-term effects of a topical treatment with ascorbic acid and madecassoside in photoaged human skin](https://pubmed.ncbi.nlm.nih.gov/18503551/) Centella asiatica leaf extract · Experimental Dermatology, 2008
- [Design, characterization, and clinical evaluation of argan oil nanostructured lipid carriers to improve skin hydration](https://pubmed.ncbi.nlm.nih.gov/25143733/) Argania spinosa kernel oil · International Journal of Nanomedicine, 2014
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [The Effects of a Standardized Extract of Centella asiatica on Postlaser Resurfacing Wound Healing on the Face: A Split-Face, Double-Blind, Randomized, Placebo-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/32310680/) Madecassoside · Journal of Alternative and Complementary Medicine, 2020
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum leaf extract flower · Genes, 2020
- [Anti-inflammatory effects of concentrated ethanol extracts of Edelweiss (Leontopodium alpinum Cass.) callus cultures towards human keratinocytes and endothelial cells](https://pubmed.ncbi.nlm.nih.gov/23093820/) Leontopodium alpinum leaf extract flower · Mediators of Inflammation, 2012
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol · The Journal of Dermatological Treatment, 2017
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [Systematic Study of Paeonol/Madecassoside Co-Delivery Nanoemulsion Transdermal Delivery System for Enhancing Barrier Repair and Anti-Inflammatory Efficacy](https://pubmed.ncbi.nlm.nih.gov/37446936/) Centella asiatica, Centella asiatica leaf extract, Paeonia albiflora flower extract, Centella asiatica extract · Molecules, 2023
- [Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function](https://pubmed.ncbi.nlm.nih.gov/35409270/) Rosamarinus officinalis leaf extract rosemary leaf extract · International Journal of Molecular Sciences, 2022
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Evaluation of dermal extracellular matrix and epidermal-dermal junction modifications using matrix-assisted laser desorption/ionization mass spectrometric imaging, in vivo reflectance confocal microscopy, echography, and histology: effect of age and peptide applications](https://pubmed.ncbi.nlm.nih.gov/25817264/) Palmitoyl tetrapeptide-7 · Journal of Cosmetic Dermatology, 2015
- [Efficacy and safety of moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese versus 0.02% triamcinolone acetonide cream in decreasing adverse reaction and downtime after ablative fractional carbon dioxide laser resurfacing: A split-face, double-blinded, randomized, controlled trial](https://pubmed.ncbi.nlm.nih.gov/30945430/) Centella asiatica leaf extract · Journal of Cosmetic Dermatology, 2019
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Development of solid lipid microparticles (SLMs) containing asiatic acid for topical treatment of acne: Characterization, stability, in vitro and in vivo anti-acne assessment](https://pubmed.ncbi.nlm.nih.gov/38460769/) Centella asiatica leaf extract · International Journal of Pharmaceutics, 2024
- [Clinical Development and Evaluation of a Multi-Component Dissolving Microneedle Patch for Skin Pigmentation Disorders](https://pubmed.ncbi.nlm.nih.gov/37571190/) 3-o-ethyl ascorbic acid · Polymers, 2023
- [Moisturizing effect of serine-loaded solid lipid nanoparticles and polysaccharide-rich extract of root Phragmites communis incorporated in hydrogel bases](https://pubmed.ncbi.nlm.nih.gov/27778274/) Serine · Archives of Pharmacal Research, 2017
- [Formulation of Ascorbic Acid and Betaine-based Therapeutic Deep Eutectic System for Enhanced Transdermal Delivery of Ascorbic Acid](https://pubmed.ncbi.nlm.nih.gov/38794349/) 3-o-ethyl ascorbic acid ascorbic acid · Pharmaceutics, 2024
- [Combined Skin Moisturization of Liposomal Serine Incorporated in Hydrogels Prepared with Carbopol ETD 2020, Rhesperse RM 100 and Hyaluronic Acid](https://pubmed.ncbi.nlm.nih.gov/26557021/) Serine · The Korean Journal of Physiology & Pharmacology, 2015
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol · Journal of Cosmetic Dermatology, 2025
- [Formulation and evaluation of exotic fat based cosmeceuticals for skin repair](https://pubmed.ncbi.nlm.nih.gov/20046792/) Mangifera indica seed butter · Indian Journal of Pharmaceutical Sciences, 2008
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Effect of isosecotanapartholide isolated from Artemisia princeps Pampanini on IL‑33 production and STAT‑1 activation in HaCaT keratinocytes](https://pubmed.ncbi.nlm.nih.gov/28447741/) Artemisia princeps leaf extract · Molecular Medicine Reports, 2017
- [Development and efficacy assessments of tea seed oil makeup remover](https://pubmed.ncbi.nlm.nih.gov/27988044/) Camellia sinensis seed oil · Annales Pharmaceutiques Francaises, 2017
- [Effect of an Emollient Emulsion Containing 15.0% of Caprylic/Capric Triglyceride on the Urocanic Acid of the Stratum Corneum](https://pubmed.ncbi.nlm.nih.gov/37109405/) Caprylic capric triglyceride · Life, 2023
- [Effects of fermented tea seed oil on the skin lipid barrier and microbiome of sensitive skin](https://pubmed.ncbi.nlm.nih.gov/41319188/) Camellia sinensis seed oil · International Journal of Cosmetic Science, 2026
- [Efficacy and safety of combination cream of stimu-tex AS™ (spent grain wax, Argania Spinosa Kernel oil, Butyrospermum Parkii (shea butter) extract), and saccharide isomerate after fractional CO2 laser procedure: split-face, double blinded, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/41134387/) Butyrospermum parkii butter shea butter · Lasers in Medical Science, 2025
- [Clinical Evaluation of a Soap-Free Cleansing Lotion Containing Sodium Cocoyl Apple Amino Acids for Effective Impurity Removal and Skin Barrier Preservation in Healthy Adults With Diverse Skin Types](https://pubmed.ncbi.nlm.nih.gov/40978887/) Sodium cocoyl apple amino acids · Cureus, 2025
- [Efficacy of a Topical Formulation on Skin Hydration and Barrier Function in Individuals With Xerosis: A 28-Day Randomized, Split-Leg, Untreated-Controlled Trial](https://pubmed.ncbi.nlm.nih.gov/42108609/) Dipotassium glycyrrhizate · Journal of Cosmetic Dermatology, 2026
- [Targeting Circadian Rhythm for the Regulation of Skin Collagen Metabolism](https://pubmed.ncbi.nlm.nih.gov/41527525/) Palmitoyl tripeptide-1 · Journal of Cosmetic Dermatology, 2026

## The brands

- Korean skincare: [Dr. Althea](https://lovi.care/skincare/sa/brands/dr-althea)
- Spanish skincare: [Natura Bissé](https://lovi.care/skincare/sa/brands/natura-bisse)

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- [Dr. Althea vs Purito](https://lovi.care/skincare/sa/compare/dr-althea-vs-purito)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

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- Canada: https://lovi.care/skincare/ca/compare/dr-althea-vs-natura-bisse
- Australia: https://lovi.care/skincare/au/compare/dr-althea-vs-natura-bisse
- Singapore: https://lovi.care/skincare/sg/compare/dr-althea-vs-natura-bisse
- Saudi Arabia: https://lovi.care/skincare/sa/compare/dr-althea-vs-natura-bisse (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/dr-althea-vs-natura-bisse