# Cetaphil vs SK-II

Page: https://lovi.care/skincare/sa/compare/cetaphil-vs-sk-ii

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for Saudi Arabia.

Cetaphil and SK-II are established skincare brands offering distinct approaches to daily care. The American brand features cleansers, moisturizers, [serums](https://lovi.care/skincare/sa/ingredients/serum), and sunscreens with [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin), [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide), and [panthenol](https://lovi.care/skincare/sa/ingredients/panthenol) to suit combination and acne-prone skin, while the Japanese brand provides nourishing moisturizers, targeted serums, restorative masks, and clarifying toners powered by pitera for dry sensitive and combination skin. Both lines address targeted concerns like dark spots and mature skin, yet they differ fundamentally through their heritage, signature formulations, and primary active ingredients.

Cetaphil is an American skincare brand founded in 1947 and owned by Galderma Group AG.

[en.wikipedia.org](https://en.wikipedia.org/wiki/Cetaphil) [cetaphil.co.uk](https://www.cetaphil.co.uk/why-cetaphil/our-story.html)

SK-II is a Japanese skincare brand founded in 1980 and owned by The Procter & Gamble Company since 1991.

[en.wikipedia.org](https://en.wikipedia.org/wiki/SK-II) [discoversk-ii.wixsite.com](https://discoversk-ii.wixsite.com/home/brand-history) [glossy.co](https://www.glossy.co/beauty/despite-strong-results-in-beauty-in-the-first-quarter-pg-will-eliminate-thousands-of-jobs/)

This page compares some of the most popular Cetaphil and SK-II products; for every product of both brands, with a fit score for your own skin, [use the Lovi app](https://app.pora.ai/vqqJ/j1xj2b6o?af_sub2=compare&af_sub3=selection_note&af_sub4=pgb4a485758e).

### Popular Cetaphil vs SK-II products

#### SK-II

- [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Skinpower Advanced Cream](https://lovi.care/skincare/sa/p/sk-ii/skinpower-advanced-cream/for/mature-skin) — High fit — [SAR 1,289.20 at Amazon](https://www.amazon.sa/dp/B0CFW488TZ?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Ultraura Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-ultraura-essence/for/acne-prone-skin) — Superior fit
- [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Genoptics Spot Essence](https://lovi.care/skincare/sa/p/sk-ii/genoptics-spot-essence/for/dark-spots) — Average fit

#### Cetaphil

- [Gentle Skin Cleanser](https://lovi.care/skincare/sa/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [SAR 39.95 at Amazon](https://www.amazon.sa/dp/B09ZFCJ963?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Moisturizing Cream](https://lovi.care/skincare/sa/p/cetaphil/moisturizing-cream/for/dry-skin) — Average fit — [SAR 63.99 at Amazon](https://www.amazon.sa/dp/B09WJ7D9SP?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Daily Facial Cleanser](https://lovi.care/skincare/sa/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [SAR 120.08 at Amazon](https://www.amazon.sa/dp/B099MSZX25?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Moisturizing Lotion](https://lovi.care/skincare/sa/p/cetaphil/moisturizing-lotion/for/sensitive-skin) — Average fit — [SAR 44.95 at Amazon](https://www.amazon.sa/dp/B09X188Z5J?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Gentle Exfoliating SA Cleanser](https://lovi.care/skincare/sa/p/cetaphil/gentle-exfoliating-sa-cleanser/for/acne-prone-skin) — High fit — [SAR 82.37 at Amazon](https://www.amazon.sa/dp/B0CZDDGCQL?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Moisturising Cream](https://lovi.care/skincare/sa/p/cetaphil/moisturising-cream/for/dry-sensitive-skin) — Average fit
- [Gentle Cleansing Bar](https://lovi.care/skincare/sa/p/cetaphil/gentle-cleansing-bar/for/dry-skin) — High fit — [SAR 17.95 at Amazon](https://www.amazon.sa/dp/B00VK7U0WU?tag=lovisa02-21&linkCode=osi&th=1&psc=1)
- [Extra Gentle Daily Scrub](https://lovi.care/skincare/sa/p/cetaphil/extra-gentle-daily-scrub/for/sensitive-skin) — Superior fit — [SAR 56.30 at Amazon](https://www.amazon.sa/dp/B07GDVHLB1?tag=lovisa02-21&linkCode=osi&th=1&psc=1)

## People Say

Cetaphil

SK-II

- Hydration and moisture Mostly Mentioned Mostly Mentioned “cleared up flaky skin — Cetaphil Moisturizing Cream” “healed my dry patches — Cetaphil Moisturising Cream” “flooded my skin with moisture — SK-II Facial Treatment Mask” “skin feels deeply hydrated, plump, and smoother — SK-II Skinpower Advanced Cream”
- Gentle on sensitive skin Mostly Mentioned Sometimes Noted “The only thing my reactive skin tolerates. — Cetaphil Gentle Skin Cleanser” “No breakouts since switching to this. — Cetaphil Gentle Skin Cleanser” “cleans without stripping — Cetaphil Daily Facial Cleanser” “Watery consistency — SK-II Facial Treatment Clear Lotion”
- Lightweight and non-greasy Often Mentioned Often Mentioned “absorbs instantly — Cetaphil Moisturizing Lotion” “Absorbs quickly into skin without residue — Cetaphil Daily Hydrating Lotion” “drinks right into the skin — SK-II Facial Treatment Essence” “Absorbs into the skin quickly. — SK-II Genoptics Ultraura Essence”
- Skin smoothing and softening Sometimes Noted Sometimes Noted “pores became miraculously invisible — SK-II Facial Treatment Mask” “Smoother skin — SK-II Facial Treatment Clear Lotion” “Skin felt softer after one use — Cetaphil Gentle Exfoliating SA Cleanser”
- Improves texture and radiance Not noted Often Mentioned “skin feels soft as butter — SK-II Facial Treatment Essence” “gives a glass skin look — SK-II Facial Treatment Essence” “leaves me with a red carpet glow — SK-II Facial Treatment Mask”
- Brightening and complexion Rarely Noted Often Mentioned “Skin looks brighter — SK-II Genoptics Spot Essence” “My skin is glowing now. — SK-II Genoptics Ultraura Essence” “Reduced sun spots — SK-II Genoptics Spot Essence” “skin looks more radiant — Cetaphil Vitamin C Serum”
- High price point Rarely Noted Mostly Mentioned “expensive for drugstore — Cetaphil Moisturizing Cream” “way too expensive — SK-II Facial Treatment Essence”
- Lack of results Not noted Often Mentioned “did absolutely nothing — SK-II Facial Treatment Essence”
- Formula changes and irritation Sometimes Noted Rarely Noted “Contains fragrance, methylparaben, and benzyl alcohol. — SK-II Genoptics Ultraura Essence” “Caused breakouts, small bumps, redness/irritation, fungal acne trigger. — SK-II Facial Treatment Cleansing Oil” “Face burns — SK-II Genoptics Spot Essence” “New version burns my face. — Cetaphil Gentle Skin Cleanser”
- Chemical or unusual smell Rarely Noted Often Mentioned “has a slight chemical scent — Cetaphil Moisturizing Cream” “Smell is too strong like chemical extract — Cetaphil Extra Gentle Daily Scrub” “Smells like hospital soap. — Cetaphil Oily Skin Cleanser” “smells like dirty feet — SK-II Facial Treatment Essence”

### Cetaphil vs SK-II routines for dry skin

#### Cetaphil-focused routine

- Cleanser: [Gentle Skin Cleanser](https://lovi.care/skincare/sa/p/cetaphil/gentle-skin-cleanser/for/dry-skin) — Superior fit — [SAR 39.95 at Amazon](https://www.amazon.sa/dp/B09ZFCJ963?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/sa/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/dry-skin) — High fit — [SAR 135.00 at Amazon](https://www.amazon.sa/dp/B09C2CYDHD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Moisturizer: [Rich Hydrating Night Cream](https://lovi.care/skincare/sa/p/cetaphil/rich-hydrating-night-cream/for/dry-skin) — Superior fit — [SAR 70.83 at Amazon](https://www.amazon.sa/dp/B01MG4PVTR?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 50](https://lovi.care/skincare/sa/p/cetaphil/sheer-mineral-sunscreen-spf-50/for/dry-skin) — Superior fit — [SAR 125.00 at Amazon](https://www.amazon.sa/dp/B08HJKQP7X?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/sa/p/missha/ultra-hyalon-cleansing-cream/for/dry-skin) — Superior fit — [SAR 65.11 at Amazon](https://www.amazon.sa/dp/B084Q16G8D?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [ROUND LAB 1025 Dokdo Cleansing Water](https://lovi.care/skincare/sa/p/round-lab/1025-dokdo-cleansing-water/for/dry-skin) — Superior fit — [SAR 72.64 at Amazon](https://www.amazon.sa/dp/B0F625GKWW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/sa/p/cetaphil/gentle-exfoliating-sa-lotion/for/dry-skin) — Caution fit — [SAR 132.33 at Amazon](https://www.amazon.sa/dp/B0CZDMS6G6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Mediheal Watermide Essential Mask](https://lovi.care/skincare/sa/p/mediheal/watermide-essential-mask/for/dry-skin) — Superior fit — [SAR 234.73 at Amazon](https://www.amazon.sa/dp/B0FMFZRJTD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### SK-II-focused routine

- Cleanser: [La Roche-Posay Toleriane Hydrating Gentle Cleanser](https://lovi.care/skincare/sa/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — [SAR 297.00 at Amazon](https://www.amazon.sa/dp/B00PL7OQI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/sa/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — [SAR 75.00 at Amazon](https://www.amazon.sa/dp/B09D7QJP1M?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/dry-skin) — High fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/dry-skin) — Caution fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/dry-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [FANCL Facial Washing Powder](https://lovi.care/skincare/sa/p/fancl/facial-washing-powder/for/dry-skin) — High fit — [SAR 130.30 at Amazon](https://www.amazon.sa/dp/B01KTJXVI4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Nourishing Mask: [Facial Treatment Mask](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-mask/for/dry-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B078MQP5ZF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy Cetaphil routine · SAR 1,005.89 · 84% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B09ZFCJ963&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B01MG4PVTR&Quantity.3=1&ASIN.4=B08HJKQP7X&Quantity.4=1&ASIN.5=B084Q16G8D&Quantity.5=1&ASIN.6=B0F625GKWW&Quantity.6=1&ASIN.7=B0CZDMS6G6&Quantity.7=1&ASIN.8=B01KTJXVI4&Quantity.8=1&ASIN.9=B0FMFZRJTD&Quantity.9=1&AssociateTag=lovisa02-21) [Buy SK-II routine · SAR 2,157.75 · 83% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00PL7OQI4&Quantity.1=1&ASIN.2=B000H723LU&Quantity.2=1&ASIN.3=B09D7QJP1M&Quantity.3=1&ASIN.4=B084M1R6RH&Quantity.4=1&ASIN.5=B072C3MCDH&Quantity.5=1&ASIN.6=B08H4QPM19&Quantity.6=1&ASIN.7=B01KTJXVI4&Quantity.7=1&ASIN.8=B078MQP5ZF&Quantity.8=1&AssociateTag=lovisa02-21) [See multi-brand routine · 96% fit](https://lovi.care/skincare/sa/skin/dry-skin)

### Cetaphil vs SK-II routines for oily skin

#### SK-II-focused routine

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/sa/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — [SAR 36.33 at Amazon](https://www.amazon.sa/dp/B07C5SKVL7?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Some By Mi Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/sa/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — [SAR 53.04 at Amazon](https://www.amazon.sa/dp/B08125WDCF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/oily-skin) — Average fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/oily-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/oily-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/oily-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Cetaphil-focused routine

- Cleanser: [Daily Facial Cleanser](https://lovi.care/skincare/sa/p/cetaphil/daily-facial-cleanser/for/oily-skin) — Superior fit — [SAR 120.08 at Amazon](https://www.amazon.sa/dp/B099MSZX25?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/sa/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/oily-skin) — Average fit — [SAR 135.00 at Amazon](https://www.amazon.sa/dp/B09C2CYDHD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ceramide Serum](https://lovi.care/skincare/sa/p/cetaphil/ceramide-serum/for/oily-skin) — High fit — [SAR 127.65 at Amazon](https://www.amazon.sa/dp/B0CZD72G5W?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Oil Control](https://lovi.care/skincare/sa/p/cetaphil/oil-control/for/oily-skin) — Average fit — [SAR 124.00 at Amazon](https://www.amazon.sa/dp/B07GDT961B?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/oily-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Caudalie Vinopure Purifying Toner](https://lovi.care/skincare/sa/p/caudalie/vinopure-purifying-toner/for/oily-skin) — Superior fit — [SAR 187.00 at Amazon](https://www.amazon.sa/dp/B0GFGP11BW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/sa/p/cetaphil/gentle-exfoliating-sa-lotion/for/oily-skin) — Average fit — [SAR 132.33 at Amazon](https://www.amazon.sa/dp/B0CZDMS6G6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/oily-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [Goldfaden MD Facial Detox Mask](https://lovi.care/skincare/sa/p/goldfaden-md/facial-detox-mask/for/oily-skin) — Superior fit — [SAR 328.29 at Amazon](https://www.amazon.sa/dp/B06Y8R9VGG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy SK-II routine · SAR 1,935.93 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B07C5SKVL7&Quantity.1=1&ASIN.2=B08125WDCF&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy Cetaphil routine · SAR 1,557.81 · 85% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B099MSZX25&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B0CZD72G5W&Quantity.3=1&ASIN.4=B07GDT961B&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0GFGP11BW&Quantity.6=1&ASIN.7=B0CZDMS6G6&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B06Y8R9VGG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/oily-skin)

### Cetaphil vs SK-II routines for combination skin

#### SK-II-focused routine

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/sa/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — [SAR 191.00 at Amazon](https://www.amazon.sa/dp/B00AU9EBTC?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Paula's Choice Skin Balancing Pore-Reducing Toner](https://lovi.care/skincare/sa/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — [SAR 166.90 at Amazon](https://www.amazon.sa/dp/B008EPPIQ4?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Facial Treatment Essence](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-essence/for/combination-skin) — High fit — [SAR 341.64 at Amazon](https://www.amazon.sa/dp/B000H723LU?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [CeraVe AM Facial Moisturizing Lotion SPF 30](https://lovi.care/skincare/sa/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — [SAR 46.95 at Amazon](https://www.amazon.sa/dp/B07C5VGNLY?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Facial Treatment Cleansing Oil](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-cleansing-oil/for/combination-skin) — Average fit — [SAR 365.23 at Amazon](https://www.amazon.sa/dp/B084M1R6RH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Facial Treatment Clear Lotion](https://lovi.care/skincare/sa/p/sk-ii/facial-treatment-clear-lotion/for/combination-skin) — High fit — [SAR 384.94 at Amazon](https://www.amazon.sa/dp/B072C3MCDH?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/sa/p/peach-and-lily/glass-skin-refining-serum/for/combination-skin) — Superior fit — [SAR 222.00 at Amazon](https://www.amazon.sa/dp/B08H4QPM19?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

#### Cetaphil-focused routine

- Cleanser: [Daily Facial Cleanser](https://lovi.care/skincare/sa/p/cetaphil/daily-facial-cleanser/for/combination-skin) — High fit — [SAR 120.08 at Amazon](https://www.amazon.sa/dp/B099MSZX25?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- Hydrating Toner: [Healthy Radiance Brightness Refresh Toner](https://lovi.care/skincare/sa/p/cetaphil/healthy-radiance-brightness-refresh-toner/for/combination-skin) — High fit — [SAR 135.00 at Amazon](https://www.amazon.sa/dp/B09C2CYDHD?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Once a week
- Moisturizer: [Ceramide Serum](https://lovi.care/skincare/sa/p/cetaphil/ceramide-serum/for/combination-skin) — High fit — [SAR 127.65 at Amazon](https://www.amazon.sa/dp/B0CZD72G5W?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning · Evening · Once a week
- SPF: [Sheer Mineral Sunscreen SPF 50](https://lovi.care/skincare/sa/p/cetaphil/sheer-mineral-sunscreen-spf-50/for/combination-skin) — Superior fit — [SAR 125.00 at Amazon](https://www.amazon.sa/dp/B08HJKQP7X?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Morning
- Pre-Cleanser: [Shu Uemura Ultime8 Sublime Beauty Cleansing Oil](https://lovi.care/skincare/sa/p/shu-uemura/ultime8-sublime-beauty-cleansing-oil/for/combination-skin) — Superior fit — [SAR 245.95 at Amazon](https://www.amazon.sa/dp/B0DNJKPSB8?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Cleansing Toner: [Medicube Zero Pore Pad 2.0](https://lovi.care/skincare/sa/p/medicube/zero-pore-pad-2-0/for/combination-skin) — Superior fit — [SAR 64.80 at Amazon](https://www.amazon.sa/dp/B0CVRCR6VF?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening
- Serum or Treatment: [Gentle Exfoliating SA Lotion](https://lovi.care/skincare/sa/p/cetaphil/gentle-exfoliating-sa-lotion/for/combination-skin) — High fit — [SAR 132.33 at Amazon](https://www.amazon.sa/dp/B0CZDMS6G6?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Evening · Once a week
- Enzyme Powder: [Dermalogica Daily Microfoliant](https://lovi.care/skincare/sa/p/dermalogica/daily-microfoliant/for/combination-skin) — Superior fit — [SAR 157.51 at Amazon](https://www.amazon.sa/dp/B001VMJSCW?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week
- Cleansing Mask: [KORA Organics Turmeric Brightening & Exfoliating Mask](https://lovi.care/skincare/sa/p/kora-organics/turmeric-brightening-and-exfoliating-mask/for/combination-skin) — Superior fit — [SAR 168.77 at Amazon](https://www.amazon.sa/dp/B09G7PCTTG?tag=lovisa02-21&linkCode=osi&th=1&psc=1) — Once a week

[Buy SK-II routine · SAR 2,044.94 · 90% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B00AU9EBTC&Quantity.1=1&ASIN.2=B008EPPIQ4&Quantity.2=1&ASIN.3=B000H723LU&Quantity.3=1&ASIN.4=B07C5VGNLY&Quantity.4=1&ASIN.5=B084M1R6RH&Quantity.5=1&ASIN.6=B072C3MCDH&Quantity.6=1&ASIN.7=B08H4QPM19&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [Buy Cetaphil routine · SAR 1,277.09 · 89% fit](https://www.amazon.sa/gp/aws/cart/add.html?ASIN.1=B099MSZX25&Quantity.1=1&ASIN.2=B09C2CYDHD&Quantity.2=1&ASIN.3=B0CZD72G5W&Quantity.3=1&ASIN.4=B08HJKQP7X&Quantity.4=1&ASIN.5=B0DNJKPSB8&Quantity.5=1&ASIN.6=B0CVRCR6VF&Quantity.6=1&ASIN.7=B0CZDMS6G6&Quantity.7=1&ASIN.8=B001VMJSCW&Quantity.8=1&ASIN.9=B09G7PCTTG&Quantity.9=1&AssociateTag=lovisa02-21) [See multi-brand routine · 97% fit](https://lovi.care/skincare/sa/skin/combination-skin)

## Questions and answers

### Cetaphil or SK-II: which is better?

Both brands perform well, but SK-II does better for skin smoothing, texture, and brightening, while Cetaphil is more gentle on sensitive skin. The products on this page help deliver effective daily care depending on whether you prioritize anti-aging results or budget-friendly, non-stripping hydration.

### What is the difference between Cetaphil and SK-II?

Cetaphil and SK-II are skincare brands with different origins, key ingredients, and strengths, as Cetaphil features key ingredients like [niacinamide](https://lovi.care/skincare/sa/ingredients/niacinamide) and [glycerin](https://lovi.care/skincare/sa/ingredients/glycerin) to help soothe sensitive skin, while SK-II uses Pitera to help improve skin texture and radiance.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/)

### Cetaphil or SK-II for dry skin?

Both Cetaphil and SK-II achieve a High routine fit for dry skin. The products on this page help hydrate and moisturize the skin equally well, though Cetaphil is particularly noted for being gentle on sensitive skin.

### Cetaphil or SK-II: which moisturizer is better?

Both brands offer moisturizers for different skin needs, with Cetaphil leaning toward gentle hydration and SK-II focusing on texture and radiance. For dry skin, the products on this page provide an equal level of fit, while SK-II holds a superior fit level for combination skin, acne-prone skin, and dry sensitive skin.

### Which is more affordable, Cetaphil or SK-II?

Cetaphil is more affordable than SK-II, while SK-II's reviewers note a high price point is a drawback for Cetaphil products on this page.

### Cetaphil or SK-II for oily skin?

Both Cetaphil and SK-II achieve a High routine fit level for oily skin. The products on this page help provide suitable daily care for this skin type without added fragrance.

### Cetaphil or SK-II for sensitive skin?

Both Cetaphil and SK-II achieve a High routine fit for sensitive skin. Reviewers note that Cetaphil tends to do better for being gentle on sensitive skin.

### Cetaphil or SK-II for acne-prone skin?

For acne-prone skin, SK-II has a Superior routine fit, while Cetaphil is rated High. Reviewers note that SK-II is better for improving texture and radiance, whereas Cetaphil features gentle, non-stripping cleansers.

### Cetaphil or SK-II for combination skin?

For combination skin, SK-II reaches a Superior Lovi fit level while Cetaphil achieves a High Lovi fit level. Reviewers indicate that SK-II performs better for skin smoothing and softening, improving texture and radiance, and brightening and complexion.

### Cetaphil or SK-II for skin with dark spots?

Both brands are a High fit for skin with dark spots, with review themes showing SK-II does better for brightening and complexion while Cetaphil is noted for having a high price point and lack of results. Niacinamide helps reduce cutaneous pigmentation and suppress melanosome transfer.

[The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/) [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Cetaphil or SK-II for mature skin?

Both Cetaphil and SK-II achieve a High routine fit for mature skin. The products on this page help improve skin quality and hydration.

[Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

## Research behind their key ingredients

- [The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer](https://pubmed.ncbi.nlm.nih.gov/12100180/) Nicotinamide w, Niacinamide · The British Journal of Dermatology, 2002
- [Mechanistic Basis and Clinical Evidence for the Applications of Nicotinamide (Niacinamide) to Control Skin Aging and Pigmentation](https://pubmed.ncbi.nlm.nih.gov/34439563/) Niacinamide · Antioxidants, 2021
- [Benefits of topical hyaluronic acid for skin quality and signs of skin aging: From literature review to clinical evidence](https://pubmed.ncbi.nlm.nih.gov/36200921/) Hyaluronic acid, Sodium hyaluronate · Dermatologic Therapy, 2022
- [Topical use of dexpanthenol in skin disorders](https://pubmed.ncbi.nlm.nih.gov/12113650/) Panthenol, D-pantothenyl alcohol · American Journal of Clinical Dermatology, 2002
- [Topical ascorbic acid on photoaged skin. Clinical, topographical and ultrastructural evaluation: double-blind study vs. placebo](https://pubmed.ncbi.nlm.nih.gov/12823436/) Sodium ascorbyl phosphate ascorbic acid, Ascorbyl palmitate ascorbic acid · Experimental Dermatology, 2003
- [Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/31975502/) Ascorbic acid, Tocopherol · Journal of Cosmetic Dermatology, 2020
- [Effects of menthol and cold on histamine-induced itch and skin reactions in man](https://pubmed.ncbi.nlm.nih.gov/7624016/) Peppermint leaf extract · Neuroscience Letters, 1995
- [Anti-microbial and -inflammatory activity and efficacy of phytosphingosine: an in vitro and in vivo study addressing acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/18489348/) Phytosphingosine · International Journal of Cosmetic Science, 2007
- [Prospective, randomized, double-blind assessment of topical bakuchiol and retinol for facial photoageing](https://pubmed.ncbi.nlm.nih.gov/29947134/) Bakuchiol · The British Journal of Dermatology, 2019
- [Effects of ascorbic acid on gingival melanin pigmentation in vitro and in vivo](https://pubmed.ncbi.nlm.nih.gov/19186973/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Periodontology, 2009
- [Skin penetration and stabilization of formulations containing microfine titanium dioxide as physical UV filter](https://pubmed.ncbi.nlm.nih.gov/18503414/) Titanium dioxide · International Journal of Cosmetic Science, 2000
- [The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction](https://pubmed.ncbi.nlm.nih.gov/27475700/) Allantoin · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016
- [Treatment of acne with a combination of propolis, tea tree oil, and Aloe vera compared to erythromycin cream: two double-blind investigations](https://pubmed.ncbi.nlm.nih.gov/30588129/) Aloe barbadensis leaf juice powder · Clinical Pharmacology, 2018
- [Alteration of barrier properties, stratum corneum ceramides and microbiome composition in response to lotion application on cosmetic dry skin](https://pubmed.ncbi.nlm.nih.gov/35340018/) Ceramides · Scientific Reports, 2022
- [Vitamin C mesotherapy versus topical application for gingival hyperpigmentation: a clinical and histopathological study](https://pubmed.ncbi.nlm.nih.gov/33966113/) Ascorbic acid · Clinical Oral Investigations, 2021
- [Ceramide 1 and ceramide 3 act synergistically on skin hydration and the transepidermal water loss of sodium lauryl sulfate-irritated skin](https://pubmed.ncbi.nlm.nih.gov/18717861/) Ceramide np · International Journal of Dermatology, 2008
- [Effects of Locally Applied Glycerol and Xylitol on the Hydration, Barrier Function and Morphological Parameters of the Skin](https://pubmed.ncbi.nlm.nih.gov/27349297/) Xylitol, Xylitylglucoside · Acta Dermato-venereologica, 2017
- [Effect of a topical antioxidant serum containing vitamin C, vitamin E, and ferulic acid after Q-switched 1064-nm Nd:YAG laser for treatment of environment-induced skin pigmentation](https://pubmed.ncbi.nlm.nih.gov/32052907/) Ascorbic acid · Journal of Cosmetic Dermatology, 2020
- [Green tea extract reduces induction of p53 and apoptosis in UVB-irradiated human skin independent of transcriptional controls](https://pubmed.ncbi.nlm.nih.gov/18631247/) Camellia sinensis leaf extract · Experimental Dermatology, 2009
- [Anti-inflammatory activities of colloidal oatmeal (Avena sativa) contribute to the effectiveness of oats in treatment of itch associated with dry, irritated skin](https://pubmed.ncbi.nlm.nih.gov/25607907/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2015
- [The 24-hour skin hydration and barrier function effects of a hyaluronic 1%, glycerin 5%, and Centella asiatica stem cells extract moisturizing fluid: an intra-subject, randomized, assessor-blinded study](https://pubmed.ncbi.nlm.nih.gov/28860834/) Glycerin, Concentrated glycerin · Clinical, Cosmetic and Investigational Dermatology, 2017
- [Randomized controlled study for the anti-aging effect of human adipocyte-derived mesenchymal stem cell media combined with niacinamide after laser therapy](https://pubmed.ncbi.nlm.nih.gov/33103316/) Niacinamide · Journal of Cosmetic Dermatology, 2021
- [Niacinamide mitigates SASP-related inflammation induced by environmental stressors in human epidermal keratinocytes and skin](https://pubmed.ncbi.nlm.nih.gov/32657437/) Gentlebright complex · International Journal of Cosmetic Science, 2020
- [The human stratum corneum layer: an effective barrier against dermal uptake of different forms of topically applied micronised titanium dioxide](https://pubmed.ncbi.nlm.nih.gov/11509913/) Titanium dioxide · Skin Pharmacology and Applied Skin Physiology, 2001
- [Anti-Aging Effects of Leontopodium alpinum (Edelweiss) Callus Culture Extract Through Transcriptome Profiling](https://pubmed.ncbi.nlm.nih.gov/32098197/) Leontopodium alpinum extract · Genes, 2020
- [Two superior antioxidants: Ferulic acid and ascorbic acid in reducing signs of photoaging-A split-face comparative study](https://pubmed.ncbi.nlm.nih.gov/34877760/) Sodium ascorbyl phosphate ascorbic acid · Dermatologic Therapy, 2022
- [A new topical panthenol-containing emollient: Results from two randomized controlled studies assessing its skin moisturization and barrier restoration potential, and the effect on skin microflora](https://pubmed.ncbi.nlm.nih.gov/27425824/) Panthenol, D-pantothenyl alcohol · The Journal of Dermatological Treatment, 2017
- [Senomorphic activity of a combination of niacinamide and hyaluronic acid: correlation with clinical improvement of skin aging](https://pubmed.ncbi.nlm.nih.gov/39009698/) Niacinamide · Scientific Reports, 2024
- [A Double-Blinded, Randomized, Vehicle-Controlled Study of the Efficacy of Moisturizer Containing Licochalcone A, Decanediol, L-Carnitine, and Salicylic Acid for Prevention of Acne Relapse in Asian Population](https://pubmed.ncbi.nlm.nih.gov/33150170/) Salicylic acid · BioMed Research International, 2020
- [Stable Ozonides with Vitamin E Acetate versus Corticosteroid in the Treatment of Lichen Sclerosus in Foreskin: Evaluation of Effects on Inflammation](https://pubmed.ncbi.nlm.nih.gov/30991399/) Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate · Urologia Internationalis, 2019
- [Ascorbic Acid Treatments as Effective and Safe Anti-Aging Therapies for Sensitive Skin](https://pubmed.ncbi.nlm.nih.gov/38397772/) Ascorbyl palmitate ascorbic acid · Antioxidants, 2024
- [Adenosine-loaded dissolving microneedle patches to improve skin wrinkles, dermal density, elasticity and hydration](https://pubmed.ncbi.nlm.nih.gov/29574973/) Adenosine · International Journal of Cosmetic Science, 2018
- [Comparative study of efficacy and safety of 45% mandelic acid versus 30% salicylic acid peels in mild-to-moderate acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/31553119/) Mandelic acid · Journal of Cosmetic Dermatology, 2020
- [Another Reason for Using Caffeine in Dermocosmetics: Sunscreen Adjuvant](https://pubmed.ncbi.nlm.nih.gov/31130869/) Caffeine · Frontiers in Physiology, 2019
- [Structural characterization and in vivo evaluation of retinyl palmitate in non-ionic lamellar liquid crystalline system](https://pubmed.ncbi.nlm.nih.gov/21411295/) Retinyl palmitate · Colloids and Surfaces. B, Biointerfaces, 2011
- [A Dunaliella salina Extract Counteracts Skin Aging under Intense Solar Irradiation Thanks to Its Antiglycation and Anti-Inflammatory Properties](https://pubmed.ncbi.nlm.nih.gov/35200634/) Dunaliella salina extract · Marine Drugs, 2022
- [Efficacy of a topical gel containing chitosan, chlorhexidine, allantoin and dexpanthenol for pain and inflammation control after third molar surgery: A randomized and placebo-controlled clinical trial](https://pubmed.ncbi.nlm.nih.gov/32683390/) D-pantothenyl alcohol · Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020
- [The efficacy of glycolic acid, salicylic acid, gluconolactone, and licochalcone A combined with 0.1% adapalene vs adapalene monotherapy in mild-to-moderate acne vulgaris: a double-blinded within-person comparative study](https://pubmed.ncbi.nlm.nih.gov/30858720/) Pha polyhydroxy acid · Clinical, Cosmetic and Investigational Dermatology, 2019
- [In vivo anti-ageing activity of cream containing niosomes loaded with purple glutinous rice (Oryza sativa Linn.) extract](https://pubmed.ncbi.nlm.nih.gov/32812663/) Rice extract lees extract · International Journal of Cosmetic Science, 2020
- [A comparative study of gluconolactone versus benzoyl peroxide in the treatment of acne](https://pubmed.ncbi.nlm.nih.gov/1303072/) Pha polyhydroxy acid · The Australasian Journal of Dermatology, 1992
- [Daily Fluctuation of Facial Pore Area, Roughness and Redness among Young Japanese Women; Beneficial Effects of Galactomyces Ferment Filtrate Containing Antioxidative Skin Care Formula](https://pubmed.ncbi.nlm.nih.gov/34198790/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2021
- [Efficacy of a multitargeted, salicylic acid-based dermocosmetic cream compared to benzoyl peroxide 5% in Acne vulgaris: Results from a randomized study](https://pubmed.ncbi.nlm.nih.gov/37941097/) Salicylic acid · Journal of Cosmetic Dermatology, 2024
- [Biomimetic hyaluronic acid-stabilized zinc oxide nanoparticles in acne treatment: A preclinical and clinical approach](https://pubmed.ncbi.nlm.nih.gov/40254135/) Zinc oxide · Journal of Controlled Release, 2025
- [Fatty acids based α-Tocopherol loaded nanostructured lipid carrier gel: In vitro and in vivo evaluation for moisturizing and anti-aging effects](https://pubmed.ncbi.nlm.nih.gov/32129554/) Vitamin e · Journal of Cosmetic Dermatology, 2020
- [A Lipid Mixture Enriched by Ceramide NP with Fatty Acids of Diverse Chain Lengths Contributes to Restore the Skin Barrier Function Impaired by Topical Corticosteroid](https://pubmed.ncbi.nlm.nih.gov/34348350/) Ceramide np · Skin Pharmacology and Physiology, 2022
- [Comparison of clinical efficacies of sodium ascorbyl phosphate, retinol and their combination in acne treatment](https://pubmed.ncbi.nlm.nih.gov/19134126/) Sodium ascorbyl phosphate · International Journal of Cosmetic Science, 2009
- [A Salicylic Acid-Based Dermocosmetic is Effective as an Adjunct to Benzoyl Peroxide for Mild to Moderate Acne and as Monotherapy in Maintenance Post Benzoyl Peroxide](https://pubmed.ncbi.nlm.nih.gov/38051857/) Salicylic acid · Journal of Drugs in Dermatology, 2023
- [Colloidal Oatmeal <em>(Avena Sativa)</em> Improves Skin Barrier Through Multi-Therapy Activity](https://pubmed.ncbi.nlm.nih.gov/27272074/) Avena sativa kernel extract oat kernel extract · Journal of Drugs in Dermatology, 2016
- [Efficacy of a topical serum containing L-ascorbic acid, neohesperidin, pycnogenol, tocopherol, and hyaluronic acid in relation to skin aging signs](https://pubmed.ncbi.nlm.nih.gov/35150043/) Vitamin e · Journal of Cosmetic Dermatology, 2022
- [Botulinum toxin injection as a single or combined treatment with non-cross-linked high molecular weight and low molecular weight hyaluronic acid gel for neck rejuvenation: A randomized clinical trial](https://pubmed.ncbi.nlm.nih.gov/35775872/) Hydrolyzed hyaluronic acid · Dermatologic Therapy, 2022
- [Subclinical, non-erythematous irritation with an open assay model (washing): sodium lauryl sulfate (SLS) versus sodium laureth sulfate (SLES)](https://pubmed.ncbi.nlm.nih.gov/11278060/) Sodium laureth sulfate · Food and Chemical Toxicology, 2001
- [In Vitro and Clinical Safety Assessment of the Multiple W/O/W Emulsion Based on the Active Ingredients from Rosmarinus officinalis L., Avena sativa L. and Linum usitatissimum L](https://pubmed.ncbi.nlm.nih.gov/34065623/) Avena sativa kernel extract oat kernel extract · Pharmaceutics, 2021
- [Whitening effect of alpha-bisabolol in Asian women subjects](https://pubmed.ncbi.nlm.nih.gov/20642768/) Bisabolol · International Journal of Cosmetic Science, 2010
- [Clinical evaluation of the efficacy of a facial serum containing dioic acid, glycolic acid, salicylic acid, LHA, citric acid, and HEPES in treating post-inflammatory hyperchromia and controlling oily skin in patients with acne vulgaris](https://pubmed.ncbi.nlm.nih.gov/33617668/) Citric acid · Journal of Cosmetic Dermatology, 2021
- [Reduction in the appearance of facial hyperpigmentation by topical N-undecyl-10-enoyl-L-phenylalanine and its combination with niacinamide](https://pubmed.ncbi.nlm.nih.gov/19958429/) Undecylenoyl phenylalanine · Journal of Cosmetic Dermatology, 2009
- [Assessment of Combined Ascorbyl Palmitate (AP) and Sodium Ascorbyl Phosphate (SAP) on Facial Skin Sebum Control in Female Healthy Volunteers](https://pubmed.ncbi.nlm.nih.gov/27756097/) Sodium ascorbyl phosphate · Drug Research, 2017
- [Inhibitory effects of shell of Camellia oleifera Abel extract on mushroom tyrosinase and human skin melanin](https://pubmed.ncbi.nlm.nih.gov/31033161/) Butylene glycol · Journal of Cosmetic Dermatology, 2019
- [A randomized, double-blind, vehicle-controlled study of a preparation containing undecylenoyl phenylalanine 2% in the treatment of solar lentigines](https://pubmed.ncbi.nlm.nih.gov/19874316/) Undecylenoyl phenylalanine · Clinical and Experimental Dermatology, 2010
- [The impacts of sodium lauroyl sarcosinate in facial cleanser on facial skin microbiome and lipidome](https://pubmed.ncbi.nlm.nih.gov/37990616/) Sodium lauroyl sarcosinate · Journal of Cosmetic Dermatology, 2024
- [Two-phase delivery using a horse oil and adenosine-loaded dissolving microneedle patch for skin barrier restoration, moisturization, and wrinkle improvement](https://pubmed.ncbi.nlm.nih.gov/30160014/) Adenosine · Journal of Cosmetic Dermatology, 2019
- [Synergetic Effects of Aloe Vera Extract with Trimethylglycine for Targeted Aquaporin 3 Regulation and Long-Term Skin Hydration](https://pubmed.ncbi.nlm.nih.gov/38611819/) Betaine · Molecules, 2024
- [Supramolecular collagen nanoparticles for anti-wrinkle, skin whitening, and moisturizing effects](https://pubmed.ncbi.nlm.nih.gov/39383579/) Palmitoyl tripeptide-5 · Colloids and Surfaces. B, Biointerfaces, 2025
- [Why is sodium cocoyl isethionate (SCI) mild to the skin barrier? - An in vitro investigation based on the relative sizes of the SCI micelles and the skin aqueous pores](https://pubmed.ncbi.nlm.nih.gov/17598025/) Sodium cocoyl isethionate · Journal of Cosmetic Science, 2007
- [Influence of vitamin E acetate on stratum corneum hydration](https://pubmed.ncbi.nlm.nih.gov/9706379/) Tocopheryl acetate · Arzneimittel-Forschung, 1998
- [The use of different concentrations of betaine as a reducing irritation agent in soaps monitored visually and non-invasively](https://pubmed.ncbi.nlm.nih.gov/12535284/) Betaine · Skin Research and Technology, 2003
- [Lactobionic acid in a natural alkylpolyglucoside-based vehicle: assessing safety and efficacy aspects in comparison to glycolic acid](https://pubmed.ncbi.nlm.nih.gov/20367666/) Pha polyhydroxy acid · Journal of Cosmetic Dermatology, 2010
- [Clinical efficacy and safety of nano-microneedle-assisted phenylethyl resorcinol for the treatment of infraorbital dark circles](https://pubmed.ncbi.nlm.nih.gov/32783330/) Phenylethyl resorcinol · Journal of Cosmetic Dermatology, 2021
- [Comparative physicochemical stability and clinical anti-wrinkle efficacy of transdermal emulgel preparations of 5% sodium ascorbyl phosphate and or ascorbic acid on human volunteers](https://pubmed.ncbi.nlm.nih.gov/32383548/) Sodium ascorbyl phosphate · Journal of Cosmetic Dermatology, 2021
- [Topical prevention from high energy visible light-induced pigmentation by 2-mercaptonicotinoyl glycine, but not by ascorbic acid antioxidant: 2 randomized controlled trials](https://pubmed.ncbi.nlm.nih.gov/41142247/) Ascorbyl palmitate ascorbic acid · Frontiers in Pharmacology, 2025
- [Topical Zinc Oxide Nanoparticle Formulations for Acne Vulgaris: A Systematic Review of Pre-Clinical and Early-Phase Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/41007718/) Zinc oxide · Biomedicines, 2025
- [Modulation of lipid fluidity likely contributes to the fructose/xylitol-induced acceleration of epidermal permeability barrier recovery](https://pubmed.ncbi.nlm.nih.gov/30847563/) Xylitylglucoside · Archives of Dermatological Research, 2019
- [Evaluation of the Efficacy and Safety of a Panthenol-Enriched Mask for Skin Barrier Recovery After Facial Laser Treatment: Results of a Double-Blind Randomized Controlled Study](https://pubmed.ncbi.nlm.nih.gov/40613435/) Panthenol, D-pantothenyl alcohol · Journal of Cosmetic Dermatology, 2025
- [Safety of a preservative system containing 1,2-hexanediol and caprylyl glycol](https://pubmed.ncbi.nlm.nih.gov/19514921/) Caprylyl glycol · Cutaneous and Ocular Toxicology, 2009
- [Efficacy and Tolerability of Stable Hybrid Cooperative Complexes of High- and Low-Molecular Weight Hyaluronic Acid in Asian Patients: An Open-Label Study](https://pubmed.ncbi.nlm.nih.gov/40921777/) Hydrolyzed hyaluronic acid · Aesthetic Plastic Surgery, 2026
- [Modulation of skin pigmentation by the tetrapeptide PKEK: in vitro and in vivo evidence for skin whitening effects](https://pubmed.ncbi.nlm.nih.gov/22142309/) Sodium ascorbyl phosphate · Experimental Dermatology, 2012
- [Tocopherol succinate-loaded ethosomal gel synthesized by cold method technique: Deeper biophysical characterizations for translational application on human skin](https://pubmed.ncbi.nlm.nih.gov/38268219/) Vitamin e · Journal of Cosmetic Dermatology, 2024
- [The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites](https://pubmed.ncbi.nlm.nih.gov/23438139/) Retinyl palmitate · Journal of Cosmetic Dermatology, 2013
- [Modulating effects of oatmeal extracts in the sodium lauryl sulfate skin irritancy model](https://pubmed.ncbi.nlm.nih.gov/11867969/) Avena sativa kernel extract oat kernel extract · Skin Pharmacology and Applied Skin Physiology, 2002
- [Propanediol (and) Caprylic Acid (and) Xylitol as a New Single Topical Active Ingredient against Acne: In Vitro and In Vivo Efficacy Assays](https://pubmed.ncbi.nlm.nih.gov/34771112/) Xylitylglucoside · Molecules, 2021
- [Enhanced Fluctuations in Facial Pore Size, Redness, and TEWL Caused by Mask Usage Are Normalized by the Application of a Moisturizer](https://pubmed.ncbi.nlm.nih.gov/35456214/) Galactomyces ferment filtrate, Pitera essence, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate galactomyces ferment filtrate, Pitera ferment filtrate, Sk-ii pitera concentrate, Pitera · Journal of Clinical Medicine, 2022
- [Three clinical studies showing the anti-aging benefits of sodium salicylate in human skin](https://pubmed.ncbi.nlm.nih.gov/20883290/) Sodium salicylate · Journal of Cosmetic Dermatology, 2010
- [Nanostructured Lipid Carrier Based Gel Containing α-Tocopherol and α-Tocopheryl Acetate for Synergistic Cutaneous Antiaging Efficacy](https://pubmed.ncbi.nlm.nih.gov/41309687/) Tocopheryl acetate vitamin e, Tocopheryl acetate vitamin e acetate, Tocopheryl acetate · Scientific Reports, 2025
- [Nanocomplex of quaternized cyclodextrin grafted chitosan and hyaluronic acid for a skin delivery](https://pubmed.ncbi.nlm.nih.gov/36279763/) Hydrolyzed hyaluronic acid · Colloids and Surfaces. B, Biointerfaces, 2022
- [Translational Evaluation of a Disodium Adenosine Monophosphate (AMP2Na)-Based Topical Formulation for Physiology-Aligned Skin Rejuvenation: Integrated In Vitro, Ex Vivo, and Clinical Evidence](https://pubmed.ncbi.nlm.nih.gov/42278371/) Adenosine · International Journal of Molecular Sciences, 2026
- [Evaulation of irritation potential of surfactant mixtures](https://pubmed.ncbi.nlm.nih.gov/18503452/) Sodium laureth sulfate · International Journal of Cosmetic Science, 1999
- [Glycerol crosslinked vitamin E loaded xanthan gum and gellan gum nanoemulgels for topical management of dry skin](https://pubmed.ncbi.nlm.nih.gov/41224059/) Xanthan gum · International Journal of Biological Macromolecules, 2025
- [A Double-Blind, 12-Week Study to Evaluate the Antiaging Efficacy of a Cream Containing the NFκB Inhibitor 4-Hexyl-1, 3-Phenylenediol and Ascorbic Acid-2 Glucoside in Adult Females](https://pubmed.ncbi.nlm.nih.gov/27272084/) L-ascorbic acid 2-glucoside, Ascorbyl glucoside · Journal of Drugs in Dermatology, 2016
- [Safety assessment on comedogenicity of dermatological products containing d-alpha tocopheryl acetate in Asian subjects: A double-blind randomized controlled trial](https://pubmed.ncbi.nlm.nih.gov/34471722/) Tocopheryl acetate vitamin e, Tocopheryl acetate · Contemporary Clinical Trials Communications, 2021
- [Facial disbiosis and UV filters](https://pubmed.ncbi.nlm.nih.gov/39499337/) Octocrylene · Archives of Dermatological Research, 2024
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- [Significant Reversal of Facial Wrinkle, Pigmented Spot and Roughness by Daily Application of Galactomyces Ferment Filtrate-Containing Skin Products for 12 Months-An 11-Year Longitudinal Skin Aging Rejuvenation Study](https://pubmed.ncbi.nlm.nih.gov/36769815/) Galactomyces ferment filtrate, Pitera essence, Pitera ferment filtrate galactomyces ferment filtrate, Galactomyces ferment filtrate pitera ferment filtrate, Pitera ferment filtrate, Pitera · Journal of Clinical Medicine, 2023
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## The brands

- American skincare: [Cetaphil](https://lovi.care/skincare/sa/brands/cetaphil)
- Japanese skincare: [SK-II](https://lovi.care/skincare/sa/brands/sk-ii)

## More comparisons

- [SKIN1004 vs Cetaphil](https://lovi.care/skincare/sa/compare/skin1004-vs-cetaphil)
- [SKIN1004 vs SK-II](https://lovi.care/skincare/sa/compare/skin1004-vs-sk-ii)
- [Anua vs Cetaphil](https://lovi.care/skincare/sa/compare/anua-vs-cetaphil)
- [Anua vs SK-II](https://lovi.care/skincare/sa/compare/anua-vs-sk-ii)
- [Medicube vs Cetaphil](https://lovi.care/skincare/sa/compare/medicube-vs-cetaphil)
- [Medicube vs SK-II](https://lovi.care/skincare/sa/compare/medicube-vs-sk-ii)
- [The Ordinary vs Cetaphil](https://lovi.care/skincare/sa/compare/the-ordinary-vs-cetaphil)
- [The Ordinary vs SK-II](https://lovi.care/skincare/sa/compare/the-ordinary-vs-sk-ii)
- [Beauty of Joseon vs Cetaphil](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-cetaphil)
- [Beauty of Joseon vs SK-II](https://lovi.care/skincare/sa/compare/beauty-of-joseon-vs-sk-ii)
- [COSRX vs Cetaphil](https://lovi.care/skincare/sa/compare/cosrx-vs-cetaphil)
- [COSRX vs SK-II](https://lovi.care/skincare/sa/compare/cosrx-vs-sk-ii)
- [CeraVe vs Cetaphil](https://lovi.care/skincare/sa/compare/cerave-vs-cetaphil)
- [CeraVe vs SK-II](https://lovi.care/skincare/sa/compare/cerave-vs-sk-ii)
- [La Roche-Posay vs Cetaphil](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-cetaphil)
- [La Roche-Posay vs SK-II](https://lovi.care/skincare/sa/compare/la-roche-posay-vs-sk-ii)
- [Dr. Althea vs Cetaphil](https://lovi.care/skincare/sa/compare/dr-althea-vs-cetaphil)
- [Dr. Althea vs SK-II](https://lovi.care/skincare/sa/compare/dr-althea-vs-sk-ii)
- [Some By Mi vs Cetaphil](https://lovi.care/skincare/sa/compare/some-by-mi-vs-cetaphil)
- [Some By Mi vs SK-II](https://lovi.care/skincare/sa/compare/some-by-mi-vs-sk-ii)

## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi compares products by their fit scores, calculated from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this comparison: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/compare/cetaphil-vs-sk-ii
- United Kingdom: https://lovi.care/skincare/uk/compare/cetaphil-vs-sk-ii
- Ireland: https://lovi.care/skincare/ie/compare/cetaphil-vs-sk-ii
- Germany: https://lovi.care/skincare/de/compare/cetaphil-vs-sk-ii
- France: https://lovi.care/skincare/fr/compare/cetaphil-vs-sk-ii
- Italy: https://lovi.care/skincare/it/compare/cetaphil-vs-sk-ii
- Netherlands: https://lovi.care/skincare/nl/compare/cetaphil-vs-sk-ii
- Spain: https://lovi.care/skincare/es/compare/cetaphil-vs-sk-ii
- Canada: https://lovi.care/skincare/ca/compare/cetaphil-vs-sk-ii
- Australia: https://lovi.care/skincare/au/compare/cetaphil-vs-sk-ii
- Singapore: https://lovi.care/skincare/sg/compare/cetaphil-vs-sk-ii
- Saudi Arabia: https://lovi.care/skincare/sa/compare/cetaphil-vs-sk-ii (this page)
- United Arab Emirates: https://lovi.care/skincare/ae/compare/cetaphil-vs-sk-ii