VT COSMETICS Cica Skin for mature skin

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What the research says

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Lactobionic acid produced better skin performance with a lack of skin irritation and barrier impairment compared to glycolic acid in 77 healthy volunteers.

  Journal of Cosmetic Dermatology, 2010

• An emulsion containing 10% lactobionic acid significantly reduces human skin surface pH without causing skin irritation or barrier impairment.

  Journal of Cosmetic Dermatology, 2019

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline.

  Experimental Dermatology, 2008

• Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream.

  International Journal of Cosmetic Science, 2008

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Topical propolis application significantly reduced postoperative pain, hemorrhage, and accelerated wound healing in patients undergoing tonsillectomy compared to a control group.

  Clinical and Experimental Otorhinolaryngology, 2018

• Topical treatment with ethanol propolis extract resulted in complete mycological and clinical cure in 56.25% of patients with onychomycosis, demonstrating non-toxicity and effective antifungal activity against Trichophyton spp. both in vitro and in patients.

  Frontiers in Microbiology, 2018

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Combining a 20% lactobionic acid peel with aluminum oxide crystal microdermabrasion increases skin hydration, improves elasticity, and decreases transepidermal water loss in 20 Caucasian females compared to lactobionic acid peel alone.

  Journal of Cosmetic Dermatology, 2019

• Carboxytherapy alone and combined with lactobionic acid, ferulic acid, and ascorbic acid significantly reduced vascular dark circles and combined pigmentation in the tear trough and lower eyelid of 39 Caucasian participants.

  Clinical, Cosmetic and Investigational Dermatology, 2024

• Lactobionic acid improved skin barrier function most compared to other AHAs and BHAs when tested on an ex vivo porcine skin model, confirming significant barrier-protective effects and enabling toxicity evaluation of cosmetic ingredients.

  International Journal of Molecular Sciences, 2021

Why other toners fit mature skin better

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• A Hamamelis virginiana leaf extract increased LOXL1 expression twofold, decreased elafin synthesis, restored functional elastic fibers, reduced nonfunctional elastin aggregates, decreased wrinkles, and improved skin firmness.

  Journal of Cosmetic Science, 2018

• Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects.

  International Journal of Cosmetic Science, 2018

Ingredients

Water, Glycerin, Butylene Glycol, Dimethicone, 2-Hexanediol, Pentylene Glycol, Centella Asiatica Extract, Propolis Extract, Asiaticoside, Asiatic Acid, Madecassoside, Madecassic Acid, Panthenol, Beta-Glucan, Camellia Sinensis Leaf Extract, Cranberry Fruit Extract, Lactobionic Acid, C12-14 Pareth-12, Carbomer, Glyceryl Acrylate Acrylic Acid Copolymer, Tromethamine, Melia Azadirachta Leaf Extract, Melia Azadirachta Flower Extract, Sodium Hyaluronate, Disodium Edta, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.