# Theramid Copper Peptide for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/theramid/copper-peptide/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Theramid](https://lovi.care/skincare/brands/theramid)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin, this product utilizes copper tripeptide-1 and bifida lysate ferment to stimulate collagen and repair your skin barrier, while also offering excellent skin repair and anti-aging benefits through copper tripeptide-1 and acetyl hexapeptide-1 to improve elasticity and reduce fine lines.
- Glycerin and sodium hyaluronate provide essential hydration to support your redness and irritation.
- The formulation is safe for your sensitive skin, containing no harsh or prohibited ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/theramid/copper-peptide/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/theramid/copper-peptide/for/oily-acne-prone-skin): High

## Key ingredients

Copper Tripeptide-1, Acetyl Tetrapeptide-2, Sodium Hyaluronate, Bifida Lysate Ferment, Acetyl Glutamine

## What the research says

- The combination of Thermus thermophilus and Bacillus subtilis mixed-culture ferment extract and copper tripeptide-1 GHK-Cu reduced inflammatory cytokines, protected skin explants from UV-induced damage, and improved wrinkles and skin barrier conditions compared to individual components or controls. ([Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical copper tripeptide complex on CO2 laser-resurfaced skin caused no significant reduction in erythema or objective improvement in wrinkles compared to controls, but significantly increased patient satisfaction regarding overall skin quality. ([Archives of Facial Plastic Surgery, 2006](https://pubmed.ncbi.nlm.nih.gov/16847171/))
- A novel regimen combining a hydroxy acid-based scrub and copper tripeptide serum significantly reduced adherent scalp flaking by 61.24%, increased hair density by 12.48%, increased hair thickness by 25.36%, and improved scalp skin hydration by 76.24% in adults with mild to moderate dandruff over 15 days. ([Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/39449909/))
- Copper applied transdermally as a tripeptide on human skin ex vivo permeated the tissue and was retained in amounts potentially effective for treating inflammatory diseases. ([Inflammation Research, 2010](https://pubmed.ncbi.nlm.nih.gov/20703511/))
- Treatment of immortalized human keratinocytes with Acetyl Tetrapeptide-2 increased cell stiffness across its concentration range, while Acetyl Hexapeptide-50 increased stiffness at 0.05 µg/ml but decreased it at 0.5 and 5 µg/ml compared to untreated controls. ([International Journal of Peptide Research and Therapeutics, 2018](https://pubmed.ncbi.nlm.nih.gov/30416406/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of Bifida Ferment Lysate strengthens the skin barrier function by upregulating barrier and antimicrobial peptide genes, exhibiting strong antioxidant properties, and decreasing inflammatory cytokine secretion in vitro. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37218728/))

## What reviewers say

A lightweight, fast-absorbing texture is frequently praised, and a moderate number of users report a boost in skin radiance. Some users find the high silicone content problematic for layering and note that copper peptides require careful routine planning to avoid conflicts with other active ingredients.

- Liked: Improves firmness (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Liked: Boosts radiance (sometimes noted)
- Liked: Gentle, non-irritating (sometimes noted)
- Disliked: Hard to combine (sometimes noted)
- Disliked: High silicone content (rarely noted)
- Disliked: No visible results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Theramid Copper Peptide Serum a great fit for sensitive skin?

Theramid Copper Peptide Serum is a great fit because it uses copper tripeptide-1 and bifida lysate ferment to repair your skin barrier, while glycerin and sodium hyaluronate provide essential hydration to calm redness and irritation. The formulation is also very safe for your skin, containing no harsh ingredients that could trigger discomfort.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for sensitive skin?

Copper tripeptide-1 and bifida lysate ferment make this serum a great fit because they repair your skin barrier and calm irritation, while glycerin and sodium hyaluronate provide essential hydration.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Copper Tripeptide-1 do for sensitive skin?

Copper Tripeptide-1 helps calm sensitive skin by reducing inflammation and supports tissue repair for a healthier barrier. It may also improve firmness and reduce signs of aging while being gentle enough for daily use.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Journal of Biomaterials Science. Polymer Edition, 2008](https://pubmed.ncbi.nlm.nih.gov/18644225/)

### What does Acetyl Tetrapeptide-2 do for sensitive skin?

Acetyl Tetrapeptide-2 helps firm and protect sensitive skin by supporting natural defenses against daily stress and aging. This ingredient is generally well tolerated, though sensitive skin types may benefit from formulas that also include soothing hydrators to keep the skin calm and smooth.
Sources: [Skin Pharmacology and Physiology, 2021](https://pubmed.ncbi.nlm.nih.gov/33849044/), [Pharmaceuticals, 2021](https://pubmed.ncbi.nlm.nih.gov/34451799/)

### Where does this serum go in a skincare routine for sensitive skin?

This serum goes in your evening routine, applied after your soothing toner and before your moisturizer. Putting treatments in the evening keeps things simple and provides extra safety around sun exposure, while helping your skin barrier stay calm.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying your retinol first at night, letting it absorb, and then following with this treatment serum to help repair your skin barrier. This formulation is safe and gentle for sensitive skin, though using strong actives together may occasionally cause mild dryness.

### How often should I use this serum?

This treatment is applied in the evening as part of your routine. It is safe for sensitive skin and helps keep your skin calm while smoothing fine lines.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to clog pores or cause breakouts for sensitive skin because its formulation contains no harsh or prohibited ingredients that could trigger irritation. Glycerin and sodium hyaluronate provide gentle hydration, while copper tripeptide-1 and bifida lysate ferment help repair the skin barrier safely.
Sources: [Skin Research and Technology, 2026](https://pubmed.ncbi.nlm.nih.gov/42573538/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Propanediol, Cyclopentasiloxane, Dimethicone, Betaine, Copper Tripeptide-1, Bifida Lysate Ferment, Cyclohexasiloxane, Glycerin, Sodium Chloride, Polyglyceryl-4 Isostearate, Sodium Hyaluronate, Acetyl Tetrapeptide-2, Trifluoroacetyl Tripeptide-2, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-11, Sh-Polypeptide-9, Acetyl Hexapeptide-1, Bacillus Folic Acid Extract Ferment Filtrate, Cetyl Peg Ppg-10 1 Dimethicone, Hexyl Laurate, Peg Ppg-18 18 Dimethicone, Lecithin, Acetyl Glutamine, Caprylyl Glycol, Butylene Glycol, Dextran, Disodium Edta, Acetic Acid, Lactic Acid, 1,2-Hexanediol, Sodium Benzoate, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/theramid/copper-peptide/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/theramid/copper-peptide/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/theramid/copper-peptide/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/theramid/copper-peptide/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/theramid/copper-peptide/for/sensitive-skin
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- Australia: https://lovi.care/skincare/au/p/theramid/copper-peptide/for/sensitive-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/theramid/copper-peptide/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/theramid/copper-peptide/for/sensitive-skin