# the SAEM Power Ampoule for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/the-saem/power-ampoule/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: the SAEM
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate suitability for your oily skin, as niacinamide and ethanol can help with oil regulation and mild exfoliation, though stronger oil-controlling ingredients would be beneficial for optimal results.
- The formula provides general skincare benefits like hydration and soothing, which are supportive for oily skin and concerns about oily shine.
- The product is safe for your skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing components like Centella Asiatica Extract and Honey Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/the-saem/power-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/the-saem/power-ampoule/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Sodium Hyaluronate, Ceramide Np, Palmitoyl Pentapeptide-4, Centella Asiatica Extract

## What the research says

- Ethanol enhances skin lipid bilayer permeability through the dual actions of lipid extraction and increasing lipid chain mobility, driven by its superior ability to form hydrogen bonds with lipid headgroups. ([RSC Advances, 2020](https://pubmed.ncbi.nlm.nih.gov/35497613/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))

## Why other serums fit oily skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))

## What reviewers say

The SAEM Power Ampoule line provides targeted solutions for various skin concerns. The Hydra and Vitamin versions are highly praised for delivering deep hydration and brightening effects, particularly beneficial for dry or dull skin. The Pore Tightening version is divisive; while some users with oily skin achieve a matte finish, a notable number report breakouts or no visible pore reduction. A common issue across all versions is a frequently malfunctioning dropper.

- Disliked: Defective dropper (mostly mentioned)
- Liked: Deep hydration (often mentioned)
- Liked: Fast absorption (often mentioned)
- Liked: Affordable price (sometimes noted)
- Liked: Brightening effect (sometimes noted)
- Disliked: Caused breakouts (sometimes noted)
- Disliked: Ineffective on pores (sometimes noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does the SAEM Power Ampoule work for oily skin?

This treatment is an average fit for oily skin because niacinamide and ethanol help with oil control and mild exfoliation, while soothing extracts keep skin calm. Oily skin works best with products that contain stronger oil-controlling ingredients like zinc PCA and ferulic acid to manage excess shine and pores.
Sources: [RSC Advances, 2020](https://pubmed.ncbi.nlm.nih.gov/35497613/)

### Which ingredients make this serum a good fit for oily skin?

This serum fits oily skin because niacinamide helps manage oil and ethanol provides mild exfoliation, while Centella Asiatica extract and honey extract soothe the skin. To work best for oily skin, a product of this type needs stronger oil-controlling ingredients and sebum-balancing components.

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Hyaluronic Acid do for oily skin?

Hyaluronic acid helps oily skin by reducing extra oil and sebum production without causing irritation. Clinical studies show it successfully balances oil levels while keeping the skin comfortable.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### Where does it go in a skincare routine for oily skin?

Apply this treatment in the evening after cleansing and toning. This timing keeps things simple and provides extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol by applying the serum first, waiting for it to absorb, and then following with your retinol product. This product is unlikely to irritate your skin, as it contains soothing ingredients like Centella Asiatica extract.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use it?

This treatment is used in the evening, applying it once a day for simplicity and extra safety around sun exposure. It works for your oily skin, though this skin type needs stronger oil-controlling ingredients for optimal results.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This treatment may cause breakouts for oily skin, as some reviewers note. To properly care for oily skin, a product of this type needs stronger oil-controlling ingredients.

### Is it fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (ethanol).

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — $28.88 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — $39.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Ethanol, Glycerin, Dipropylene Glycol, 1,2-Hexanediol, Niacinamide, Methyl Gluceth-20, Laminaria Japonica Extract, Eclipta Prostrata Leaf Extract, Coccinia Indica Fruit Extract, Eclipta Prostrata Extract, Melia Azadirachta Flower Extract, Melia Azadirachta Leaf Extract, Piper Methysticum Stem Extract Root Leaf, Acmella Oleracea Extract, Curcuma Longa Root Extract, Ocimum Sanctum Leaf Extract, Centella Asiatica Extract, Panax Ginseng Extract Berry, Corallina Officinalis Extract, Honey Extract, Monascus Extract, Hydrogenated Lecithin, Sodium Hyaluronate, Camellia Sinensis Seed Oil, Camellia Japonica Seed Oil, Argania Spinosa Kernel Oil, Olea Europaea Oil Fruit Olive Oil Fruit, Macadamia Ternifolia Seed Oil, Helianthus Annuus Seed Oil Sunflower Seed Oil, Jojoba Seed Oil, Ammonium Acryloyldimethyltaurate Vp Copolymer, Polyglyceryl-10 Laurate, Methylpropanediol, Ceramide Np, Sodium Citrate, Sucrose Distearate, Xanthan Gum, Citric Acid, Adenosine, Fructooligosaccharides, Disodium Edta, Beta-Glucan, Polyquaternium-51, Glyceryl Stearate, Butylene Glycol, Bifida Lysate Ferment, Panthenol, Hydrolyzed Hyaluronic Acid, Raffinose, Folic Acid, Cholesterol, Aureobasidium Pullulans Ferment, Tromethamine, Palmitoyl Pentapeptide-4, Nonapeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Hexapeptide-9, Hydrogenated Polydecene, Polyglyceryl-10 Oleate, Hydroxyacetophenone, Ethylhexylglycerin, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-saem/power-ampoule/for/oily-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/the-saem/power-ampoule/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/the-saem/power-ampoule/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/the-saem/power-ampoule/for/oily-skin
- France: https://lovi.care/skincare/fr/p/the-saem/power-ampoule/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/the-saem/power-ampoule/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/the-saem/power-ampoule/for/oily-skin
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- Canada: https://lovi.care/skincare/ca/p/the-saem/power-ampoule/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/the-saem/power-ampoule/for/oily-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/the-saem/power-ampoule/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/the-saem/power-ampoule/for/oily-skin