# The Outset Nourishing Squalane Daily Moisturizer for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [The Outset](https://lovi.care/skincare/brands/the-outset)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate suitability for normal skin, as squalane and glycerin provide emollient and humectant actions to hydrate and enhance barrier resilience. Cassia Angustifolia Polysaccharide Seed also contributes to improving skin texture and providing hydration for fine lines and wrinkles.
- The formula contains a blend of nourishing oils like sunflower and avocado oil, which offer additional emollient benefits suitable for normal skin.
- The product is safe for your normal skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/oily-acne-prone-skin): High

## Key ingredients

Squalane, Glycerin, Aloe Barbadensis Leaf Juice, Caprylic Capric Triglyceride, Persea Gratissima Oil Avocado Oil

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Topical application of a vitamin C-squalene bioconjugate significantly increased epidermal thickness, type III collagen production, and glycosaminoglycans production in human skin explants compared to free vitamin C and vitamin C-palmitate. ([Scientific Reports, 2020](https://pubmed.ncbi.nlm.nih.gov/33037252/))
- Topical cream containing saffron extract and avocado oil improved wrinkle grading, reduced nasolabial fold area and volume, and increased skin elasticity in twenty healthy volunteers over 12 weeks without allergic reactions. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31957954/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of an emollient emulsion containing 15.0% caprylic/capric triglyceride doubled the amount of urocanic acid isomers and increased skin hydration with reduced transepidermal water loss in healthy subjects, though it did not prevent ultraviolet-induced urocanic acid isomerization. ([Life, 2023](https://pubmed.ncbi.nlm.nih.gov/37109405/))
- Topical treatment with SSFAO 50% or avocado oil increased wound contraction, reepithelialization, collagen density, and tensile strength while showing anti-inflammatory activity compared to petroleum jelly in rats. ([Evidence-based Complementary and Alternative Medicine, 2013](https://pubmed.ncbi.nlm.nih.gov/23573130/))

## What reviewers say

This moisturizer is highly regarded for its lightweight, non-greasy feel and its ability to provide deep, long-lasting hydration, making it suitable for sensitive and dry skin. It is frequently noted for soothing redness and strengthening the skin barrier, leaving skin soft and nourished without irritation. A moderate number of users appreciate its clean, fragrance-free formula.

- Liked: Lightweight, non-greasy (mostly mentioned)
- Liked: Deeply hydrating (often mentioned)
- Liked: Soothes sensitive skin (often mentioned)
- Liked: Clean, fragrance-free (sometimes noted)
- Disliked: Faulty pump packaging (rarely noted)
- Disliked: May clog pores (rarely noted)
- Disliked: Not hydrating enough (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes The Outset Nourishing Squalane Daily Moisturizer a great fit for mature skin?

This moisturizer is a great fit for mature skin because squalane and glycerin hydrate dry areas and help strengthen the skin barrier. Ingredients like avocado oil and seed extracts also help smooth the look of fine lines and keep the skin feeling soft.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### Which ingredients make this cream a good fit for mature skin?

Squalane and glycerin make this cream a great fit for mature skin by hydrating and keeping the skin barrier resilient, while avocado oil and other plant oils provide extra softening benefits. Squalane also helps protect against skin stress and supports collagen, and plant seed extracts help smooth the look of fine lines and wrinkles.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/)

### What does Squalane do for mature skin?

Squalane helps keep mature skin feeling soft and smooth by boosting moisture and protecting the skin barrier. It also provides antioxidant support that helps improve the look of fine lines and wrinkles over time.
Sources: [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/), [Journal of Nanoscience and Nanotechnology, 2010](https://pubmed.ncbi.nlm.nih.gov/21137794/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this cream go in a skincare routine for mature skin?

This cream goes in your morning and evening routine as the last step before your sunscreen in the morning and after your treatment in the evening. Using a moisturizer helps lock in hydration and supports a smooth, soft feel for mature skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36607762/)

### Can I use this cream with retinol, and in what order?

You can use this moisturizer with retinol by applying the cream after your retinol treatment both morning and evening. Using a barrier-enhancing moisturizer helps keep your skin soft and smooth while reducing potential irritation from stronger treatments.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this cream twice a day as part of your morning and evening routine. Regular daily application helps keep mature skin well-hydrated, smooth, and soft while improving the look of fine lines and wrinkles.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as it has a very low risk of breakouts and lacks harsh ingredients that trigger irritation. Squalane and nourishing oils help soften the skin and smooth out fine lines without heavy residue.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31957954/)

### Can I use this cream around the eyes or on my body?

This moisturizer is safe to use around the eyes and on the body because its gentle formula has a very good safety profile. The eyelid and body skin absorb lightweight hydrators like squalane and glycerin well, though very thin areas may need extra care with rich oils.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — $22.00 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — $120.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Caprylic Capric Triglyceride, Pentylene Glycol, Glycerin, Ethylhexyl Palmitate, Cetearyl Alcohol, Squalane, Cassia Angustifolia Polysaccharide Seed, Helianthus Annuus Seed Oil Sunflower Seed Oil, Coconut Oil, Carthamus Tinctorius Seed Oil, Persea Gratissima Oil Avocado Oil, Humulus Lupulus Extract, Helianthus Annuus Extract Sunflower Extract, Helianthus Annuus Wax Seed Sunflower Wax Seed, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Aloe Barbadensis Leaf Juice, Prunus Insititia Seed Oil, Rice Bran Extract, Fucus Vesiculosus Extract, Leuconostoc Radish Root Ferment Filtrate, Leontopodium Alpinum Extract, Glycine Soja Oil Soybean Oil, Jojoba Esters, Dicaprylyl Ether, Diheptyl Succinate, Glyceryl Stearate, Carbomer, Phenoxyethanol, Citric Acid, Hydrogenated Oil, Xanthan Gum, Polyglycerin-3, Caprylyl Glycol, Capryloyl Glycerin Sebacic Acid Copolymer, Tocopheryl Acetate, Tocopherol, Tetrasodium Glutamate Diacetate, Potassium Hydroxide, Potassium Sorbate, Sodium Benzoate, Sodium Formate, Sodium Glycolate, Sodium Hydroxide, Sodium Stearoyl Glutamate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/the-outset/nourishing-squalane-daily-moisturizer/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/the-outset/nourishing-squalane-daily-moisturizer/for/mature-skin
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