# SKIN1004 Madagascar Centella Tone Brightening Capsule Ampoule for sensitive skin

**Lovi Fit: High fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [SKIN1004](https://lovi.care/skincare/brands/skin1004)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your normal skin and addresses redness and irritation with Centella Asiatica Extract and Madecassoside, which offer potent anti-inflammatory and calming benefits.
- Niacinamide and 3-O-Ethyl Ascorbic Acid further enhance skin tone and brightness, complementing the soothing effects for a more even complexion.
- The product is safe for your sensitive skin, featuring soothing ingredients and an absence of harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin): High (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Centella Asiatica Extract, Niacinamide, Tranexamic Acid, 3-O-Ethyl Ascorbic Acid, Madecassoside

## What the research says

- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Treatment with an asiaticoside-containing cream applied twice daily for 12 weeks significantly improved periorbital wrinkles in 65% of 27 female volunteers compared to a vehicle control cream. ([International Journal of Cosmetic Science, 2008](https://pubmed.ncbi.nlm.nih.gov/18452433/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))

## What reviewers say

Based on a very large amount of data, users with sensitive and acne-prone skin highly praise this ampoule for its lightweight, fast-absorbing hydration that effectively calms redness without causing irritation. Many users report achieving a healthy glow and improved skin texture. However, the brightening of dark spots is often described as a slow, gradual process that requires consistent long-term use.

- Liked: Lightweight, fast absorbing (mostly mentioned)
- Liked: Generous size, value (often mentioned)
- Liked: Soothing and gentle (often mentioned)
- Disliked: Slow brightening results (often mentioned)
- Liked: Gradual brightening (sometimes noted)
- Disliked: Capsule texture (rarely noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Not moisturizing enough (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes SKIN1004 Tone Brightening Capsule Ampoule a great fit for sensitive skin?

This product is a great fit for your sensitive skin because it uses Centella Asiatica Extract and Madecassoside to calm redness and irritation. It also includes niacinamide and vitamin C to brighten your skin tone while keeping things gentle and safe.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Which ingredients make this serum a good fit for sensitive skin?

Centella Asiatica Extract and Madecassoside make this serum a good fit because they help calm redness and irritation. They provide gentle soothing benefits that match the safety needs of easily irritated skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### What does Centella Asiatica Extract do for sensitive skin?

Centella asiatica extract helps calm sensitive skin and keeps it comfortable by easing irritation and supporting moisture retention. Using this ingredient helps soothe redness and supports a healthy skin barrier with a very low likelihood of irritation.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### What does Niacinamide do for sensitive skin?

Niacinamide helps calm sensitive skin by strengthening the skin barrier and reducing redness and irritation. It is very well tolerated and may improve overall comfort and resilience with regular use.
Sources: [Cutis, 2005](https://pubmed.ncbi.nlm.nih.gov/16209160/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### Where does this serum go in a skincare routine for sensitive skin?

This treatment goes in your evening routine after your toner and before your moisturizer. It is a great fit for sensitive skin because it addresses redness with calming ingredients while brightening your skin tone safely.

### Can I use this serum with retinol, and in what order?

You can use this treatment with retinol by applying it after your cleanser and soothing toner, and before your moisturizer. The soothing ingredients help calm the skin and are unlikely to cause irritation when layered carefully.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this serum?

You can use this treatment in your evening routine, applying it after your toner and before your moisturizer. It is a great fit for sensitive skin, helping to calm redness and irritation safely.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Can this serum clog pores, cause breakouts or purging for sensitive skin?

This serum is unlikely to cause breakouts or clog pores on sensitive skin because it is free of harsh substances and features calming ingredients like Centella Asiatica Extract. Reviewers rarely mention breakouts, and the formula is designed with a very safe profile for easily irritated skin.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $16.00 (https://www.amazon.com/dp/B09TLFY4GP?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Centella Asiatica Extract, Butylene Glycol, Glycerin, Niacinamide, Tranexamic Acid, 1,2-Hexanediol, Water, Betaine, Madecassoside, Hydrogenated Lecithin, Xylitylglucoside, Anhydroxylitol, Xylitol, Panthenol, Zea Mays Starch, Arginine, Mannitol, 3-O-Ethyl Ascorbic Acid, Microcrystalline Cellulose, Lactobacillus Ferment, Hydroxyethylcellulose, Pentylene Glycol, Glucose, Ethylhexylglycerin, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin
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- United Arab Emirates: https://lovi.care/skincare/ae/p/skin1004/madagascar-centella-tone-brightening-capsule-ampoule/for/sensitive-skin