# Shiseido VITAL PERFECTION for mature skin

**Lovi Fit: Average fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/shiseido/vital-perfection/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Shiseido](https://lovi.care/skincare/brands/shiseido)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for mature skin; other moisturizers fit it better.

## Why this fit

- Suitable for normal skin due to the presence of glycerin and squalane for humectant and emollient actions, respectively, this product offers excellent moisturizing benefits that hydrate and smooth skin texture.
- While it provides general skincare benefits, the ingredients are mostly supportive and not directly targeted at addressing your concerns with wrinkles and fine lines.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/acne-prone-skin): Low
- [Skin with dark spots](https://lovi.care/skincare/p/shiseido/vital-perfection/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/mature-skin): Average (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/shiseido/vital-perfection/for/oily-acne-prone-skin): Low

## Key ingredients

Glycerin, Dimethicone, Squalane

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- A dimethicone skin protectant lotion significantly decreased visual scoring and transepidermal water loss compared to vehicle control and SLS-only treated sites in 12 healthy humans exposed to sodium lauryl sulfate. ([Skin Research and Technology, 2000](https://pubmed.ncbi.nlm.nih.gov/11428946/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## Why other moisturizers fit mature skin better

- Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers. ([International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/))
- Nanoemulsions containing Macadamia integrifolia seed oil successfully enhanced skin hydration and reduced wrinkles in human volunteers, outperforming conventional emulsions in skin hydration enhancement. ([Nanomaterials, 2024](https://pubmed.ncbi.nlm.nih.gov/38668218/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))

## What reviewers say

Based on a very large amount of data, this rich cream is highly favored by users with mature or dry skin for its luxurious texture and ability to deeply hydrate, leaving skin feeling plump and bouncy. Many users experience an immediate glow and softer skin, with long-term benefits including improved firmness and reduced dullness. A significant number of users find the product to be expensive, and a moderate number find the floral fragrance overpowering.

- Liked: Deep hydration (mostly mentioned)
- Liked: Luxurious texture (mostly mentioned)
- Liked: Visible firming (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Pleasant experience (sometimes noted)
- Liked: Radiance and glow (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Lack of dramatic results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Shiseido Vital Perfection work for mature skin?

Shiseido Vital Perfection works for mature skin by providing good moisture with glycerin and squalane, but it is not directly targeted at addressing wrinkles and fine lines. To fit mature skin best, a moisturizing treatment needs potent anti-aging ingredients like peptides and antioxidants along with rich emollients and humectants.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for mature skin?

Glycerin and squalane make this cream a good fit by hydrating and smoothing skin texture. However, mature skin needs products with potent ingredients like peptides and antioxidants to effectively address wrinkles and fine lines.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Dimethicone do for mature skin?

Dimethicone helps keep mature skin feeling soft and smooth while protecting the skin barrier. When used regularly, it may improve skin firmness and keep the surface hydrated throughout the day.
Sources: [Dermatologic Therapy, 2012](https://pubmed.ncbi.nlm.nih.gov/22913439/), [Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/)

### Where does this cream go in a skincare routine for mature skin?

This moisturizing treatment goes near the end of your evening routine, right after your treatment serum and before bed. It helps keep your skin soft and smooth with ingredients like glycerin and squalane, though mature skin also needs targeted anti-aging actives like peptides or retinoids to properly care for wrinkles and fine lines.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it first helps prepare your skin and keeps it calm while you use your retinol treatment. A product of this type for mature skin needs targeted ingredients like peptides and antioxidants to properly smooth fine lines and wrinkles.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this cream?

You can use this moisturizing treatment daily to hydrate and smooth your skin. For mature skin, this type of product needs targeted ingredients that help smooth fine lines and wrinkles.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to cause irritation or breakouts on mature skin, as it has a very safe formula without harsh ingredients. However, because it is a rich moisturizing treatment, it may feel a bit heavy if your skin tends to get oily.

### Can I use this cream around the eyes or on my body?

Yes, you can use this moisturizing treatment around your eyes and on your body, as its gentle formula is unlikely to cause irritation on delicate areas. However, because skin is exceptionally thin around the eyes and varies greatly across body regions, this product needs targeted firming ingredients and rich hydrators like hyaluronic acid or plant extracts to truly smooth fine lines and support those specific zones.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (alcohol denat).

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — $22.00 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — $120.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

- Amazon.com: $124.10 (https://www.amazon.com/dp/B0CP67VGG7?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Dimethicone, Butylene Glycol, Peg-10 Dimethicone, Alcohol Denat, Hydrogenated Polydecene, Behenyl Alcohol, Squalane, Peg Ppg-14 7 Dimethyl Ether, Sodium Chloride, Sodium Citrate, Disodium Edta, Tocopherol, Bht, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/shiseido/vital-perfection/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/shiseido/vital-perfection/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/shiseido/vital-perfection/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/shiseido/vital-perfection/for/mature-skin
- France: https://lovi.care/skincare/fr/p/shiseido/vital-perfection/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/shiseido/vital-perfection/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/shiseido/vital-perfection/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/shiseido/vital-perfection/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/shiseido/vital-perfection/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/shiseido/vital-perfection/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/shiseido/vital-perfection/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/shiseido/vital-perfection/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/shiseido/vital-perfection/for/mature-skin