# Shiseido Bio-Performance Advanced Super Revitalizing Cream for mature skin

**Lovi Fit: Warning fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Warning.

Page: https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Shiseido](https://lovi.care/skincare/brands/shiseido)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A poor match for mature skin; the moisturizers alongside fit it better.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/oily-skin): Warning
- [Dry skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-skin): Warning
- [Combination skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/combination-skin): Warning
- [Sensitive skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/sensitive-skin): Warning
- [Acne-prone skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/acne-prone-skin): Warning
- [Skin with dark spots](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dark-spots): Warning
- [Mature skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin): Warning (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/dry-sensitive-skin): Warning
- [Oily acne-prone skin](https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/oily-acne-prone-skin): Warning

## Key ingredients

Sodium Hyaluronate, Glycerin, Raspberry Fruit Extract, Tocopheryl Acetate, Squalane

## What the research says

- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Topical raspberry ketone increased dermal IGF-I production through sensory neuron activation, promoting hair growth and increasing skin elasticity in mice and humans. ([Growth Hormone & IGF Research, 2008](https://pubmed.ncbi.nlm.nih.gov/18321745/))
- A liposoluble extract of Rubus idaeus cell cultures induced genes for skin hydration, stimulated ceramide production, increased extracellular matrix synthesis in cultured fibroblasts, and showed skin-hydrating capacity in vivo. ([International Journal of Cosmetic Science, 2015](https://pubmed.ncbi.nlm.nih.gov/25940647/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

This cream is widely celebrated for its ability to deeply hydrate and smooth dry, sun-damaged, or aging skin, often resulting in a more youthful and radiant complexion. While it is highly effective for many, individuals with sensitive skin or those sensitive to fragrance may experience irritation, and some long-term users have noted a preference for the original formula.

- Liked: Deep hydration (mostly mentioned)
- Liked: Smooth texture (often mentioned)
- Liked: Absorbs well (sometimes noted)
- Liked: Reduces lines (sometimes noted)
- Disliked: Formula changes (sometimes noted)
- Disliked: Potential irritation (sometimes noted)
- Disliked: Greasy feel (rarely noted)
- Disliked: Strong scent (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### Why does Lovi advise against Shiseido Bio-Performance Advanced Super Revitalizing Cream for mature skin?

Lovi advises against this cream for mature skin because it falls short of the higher standards needed for this skin type. A fitting product for mature skin needs potent ingredients that address wrinkles and fine lines, a rich blend of softening and hydrating components to maintain moisture balance, and nourishing antioxidants or peptides to support overall skin health.

### Which ingredients make this cream a poor fit for mature skin?

This cream is a poor match for mature skin because it lacks the potent smoothing ingredients and rich nourishment that skin of this type needs to stay soft and firm.

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### What does Glycerin do for mature skin?

Glycerin helps keep mature skin feeling soft and smooth by drawing moisture into the outer layer and locking it in. This daily hydration boost supports the skin barrier, keeping dry areas comfortable and protected against irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does it go in a skincare routine for mature skin?

This product is a poor match for mature skin, so Lovi advises against using it here. A moisturizing treatment for this skin needs rich hydrators like glycerin and sodium hyaluronate along with nourishing ingredients like squalane to keep dry skin soft and smooth.

### Can I use this cream with retinol, and in what order?

This cream is a poor match for mature skin, so Lovi advises against using it. A product of this type for mature skin needs firming peptides and barrier-restoring ceramides to keep skin smooth and protected.

### How often should I use it?

This moisturizing treatment is a poor match for mature skin, so Lovi advises against using it. Mature skin needs rich moisturizers with ingredients like hyaluronic acid, glycerin, and nourishing plant oils to stay soft and smooth.

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is a poor match for mature skin, and a product of this type needs lightweight hydrators and soothing ingredients to keep pores clear without causing breakouts.

### Can I use it around the eyes or on my body?

This moisturizing treatment is not a good match for mature skin because its type and ingredients suit the thin skin around the eyes and the skin on the body. A product for mature skin needs ingredients like sodium hyaluronate, glycerin, and botanical extracts to keep skin soft and smooth.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Journal of Biomedical Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28808192/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum, hexyl cinnamal, linalool, limonene, citronellol, and geraniol).

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — $22.00 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — $120.00 at Amazon

## Routine for mature skin

### AM

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

### PM

- Pre-Cleanser: [Dermalogica PreCleanse](https://lovi.care/skincare/p/dermalogica/precleanse/for/mature-skin) — Superior fit — $49.00 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Cleansing Toner: [Pixi Glow Tonic](https://lovi.care/skincare/p/pixi/glow-tonic/for/mature-skin) — Superior fit — $28.42 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/mature-skin) — Superior fit — $39.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon

### Weekly

- Pre-Cleanser: [Dermalogica PreCleanse](https://lovi.care/skincare/p/dermalogica/precleanse/for/mature-skin) — Superior fit — $49.00 at Amazon
- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Enzyme Powder: [Fancl Facial Washing Powder](https://lovi.care/skincare/p/fancl/facial-washing-powder/for/mature-skin) — Superior fit — $22.00 at Amazon
- Nourishing Mask: [MEDIHEAL Vita Essential Mask](https://lovi.care/skincare/p/mediheal/vita-essential-mask/for/mature-skin) — Superior fit — $22.00 at Amazon
- Serum or Treatment: [Peach & Lily Glass Skin Refining Serum](https://lovi.care/skincare/p/peach-and-lily/glass-skin-refining-serum/for/mature-skin) — Superior fit — $39.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon

## Where to buy

- Amazon.com: $115.00 (https://www.amazon.com/dp/B0002JBQFW?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Glycerin, Butylene Glycol, Isododecane, Isohexadecane, Dimethicone, Cetyl Ethylhexanoate, Hydrogenated Polydecene, Disteardimonium Hectorite, Peg-9 Polydimethylsiloxyethyl Dimethicone, Peg-150, Peg-8 Diisostearate, Phenoxyethanol, Methylparaben, Ethylparaben, Phytosteryl Macadamiate, Sodium Citrate, Parfum, Trisodium Edta, Tocopheryl Acetate, Stearyl Glycyrrhetinate, Hydroxyproline, Citric Acid, Sodium Metaphosphate, Benzyl Benzoate, Alpha-Isomethyl Ionone, Butylphenyl Methylpropional, Hexyl Cinnamal, Linalool, Limonene, Sodium Acetylated Hyaluronate, Citronellol, Geraniol, Saccharomyces Lysate Ferment Filtrate, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Iron Oxides Ci 77492, Syzygium Jambos Leaf Extract, Iron Oxides Ci 77491, Tocopherol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/shiseido/bio-performance-advanced-super-revitalizing-cream/for/mature-skin