# ROUND LAB Pine Calming Cica Ampoule for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [ROUND LAB](https://lovi.care/skincare/brands/round-lab)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Highly suitable for your dry and sensitive skin as sodium hyaluronate and hydrolyzed hyaluronic acid provide excellent humectant action to draw moisture into the skin, while asiaticoside, madecassoside, and madecasic acid calm inflammation and strengthen your skin barrier.
- The formulation is safe for your dry and sensitive skin, containing no harsh or irritating ingredients.
- This product offers relevant benefits for your dry or flaky skin and sensitivity.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Pine Extract, Centella Asiatica Extract, Sodium Hyaluronate, Glycerin, Madecassoside

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A topical antioxidant serum significantly reduced air pollution-induced skin pigmentation and proinflammatory gene expression ex vivo, and improved skin aging signs in 40 healthy adult females after 90 days of daily use. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35150043/))
- A xanthan gum and alginate-based bioadhesive film loaded with pycnogenol provides sustained drug release within 24 hours, achieves a safe maximum concentration of ~ 0.2 mg/mL for keratinocytes, and absorbs simulated wound fluid, demonstrating suitability for topical wound treatment. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/33802607/))
- Topical treatment with Pinus brutia bark extract cream significantly accelerated incision wound healing in albino rats, demonstrating a 35% decrease in MDA and a 46.8% increase in SOD activity compared to the control group. ([Die Pharmazie, 2013](https://pubmed.ncbi.nlm.nih.gov/23444785/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this ampoule is highly recommended for those with sensitive, oily, and acne-prone skin due to its fast-absorbing, watery texture that effectively calms redness and inflammation without causing breakouts. Users appreciate its gentle formulation and ability to refine skin texture. However, individuals with dry skin may find it insufficient on its own and need to layer with a richer moisturizer.

- Liked: Soothing and calming (mostly mentioned)
- Liked: Lightweight absorption (often mentioned)
- Liked: Non-irritating formula (often mentioned)
- Liked: Gentle texture improvement (sometimes noted)
- Disliked: Insufficient for dry skin (sometimes noted)
- Disliked: Small volume/price (sometimes noted)
- Disliked: Breakouts/reactions (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes ROUND LAB Pine Calming Cica Ampoule a great fit for dry sensitive skin?

This product is a great fit because sodium hyaluronate draws moisture deep into dry skin, while centella asiatica ingredients calm irritation and help strengthen your skin barrier. It also has a safe formulation with no harsh ingredients, making it very gentle for sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Which ingredients make this treatment a good fit for dry sensitive skin?

Sodium hyaluronate and hydrolyzed hyaluronic acid pull moisture into dry skin, while asiaticoside, madecassoside, and madecasic acid help calm irritation and strengthen your skin barrier. These ingredients have a strong safety profile and are unlikely to upset sensitive skin.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### What does Pine Extract do for dry sensitive skin?

Pine extract helps keep dry sensitive skin hydrated while protecting it from everyday environmental stress and UV-induced irritation. Regular use may improve skin elasticity and reduce water loss, leaving the skin feeling soft and calm.
Sources: [Skin Pharmacology and Physiology, 2016](https://pubmed.ncbi.nlm.nih.gov/26492562/), [Skin Pharmacology and Physiology, 2021](https://pubmed.ncbi.nlm.nih.gov/33789311/)

### What does Centella Asiatica Extract do for dry sensitive skin?

Centella asiatica extract helps calm dry sensitive skin by reducing irritation and improving moisture while protecting the skin barrier. Clinical studies show that regular use noticeably decreases redness and discomfort while keeping the skin soft and hydrated.
Sources: [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40682399/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening helps keep things simple and provides extra safety around sun exposure.

### Can I use this treatment with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the retinol first and then following with this ampoule to help calm your skin and draw in moisture. This product is a great fit because sodium hyaluronate and hydrolyzed hyaluronic acid pull moisture into dry skin, while asiaticoside, madecassoside, and madecasic acid help calm irritation and strengthen the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### How often should I use this treatment?

You can use this treatment in your evening routine, applying it once a day or a few times a week as your skin feels comfortable. It is well suited for dry and sensitive skin because ingredients like sodium hyaluronate draw in moisture while madecassoside calms irritation and helps strengthen your skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to cause breakouts or clogged pores for dry sensitive skin, as it has a safe formulation containing no harsh or irritating ingredients. It helps keep skin calm and hydrated with gentle ingredients like sodium hyaluronate and Centella asiatica extract.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — $39.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — $53.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — $16.75 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — $16.97 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Butylene Glycol, Dipropylene Glycol, Glycereth-26, Glycerin, 2-Hexanediol, Propanediol, Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Ethylhexyl Glycerin, Water, Glycoprotein, Indo Mulberry Leaf Extract, Yellow Lotus Root Extract, Indo Mulberry Flower Extract, Hydroxyacetophenone, Asiaticoside, Asiatic Acid, Madecassoside, Madecasic Acid, Sodium Citrate, Capryloyl Salicylic Acid, Disodium Edta, Xanthan Gum, Carbomer, Tromethamine, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/round-lab/pine-calming-cica-ampoule/for/dry-sensitive-skin