# ROUND LAB 1025 Dokdo Ampoule for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [ROUND LAB](https://lovi.care/skincare/brands/round-lab)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Highly suitable for your normal skin due to the humectant action of glycerin and hydrolyzed hyaluronic acid, alongside barrier repair from ceramide NP and hydrogenated lecithin.
- The formula offers excellent moisturizing and treatment benefits, with sea water and hydrolyzed hyaluronic acid effectively hydrating and improving skin texture.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components like sea water, panthenol, and ceramides.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/acne-prone-skin): Superior
- [Skin with dark spots](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/oily-acne-prone-skin): High

## Key ingredients

Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen, Ceramide Np, Panthenol, Chondrus Crispus Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Hybrid nanogels incorporating carrageenan, polyvinylpyrrolidone, and jojoba oil enhance and provide controlled cutaneous permeation of niacinamide, protecting human keratinocytes from UV radiation compared to standard delivery. ([Pharmaceutics, 2021](https://pubmed.ncbi.nlm.nih.gov/34834383/))
- Liposomes containing the carrageenan/echinochrome complex reduced lysosomal activity by 26%, decreased ROS levels by 23%, and improved migration by 47% in LPS-treated human HaCaT keratinocytes compared to untreated inflamed cells. ([Marine Drugs, 2024](https://pubmed.ncbi.nlm.nih.gov/39728136/))

## What reviewers say

Based on limited data, users with dehydrated and sensitive skin frequently praise this ampoule for its ability to provide deep hydration without heaviness, often describing it as "watery" and "plumping." It is widely celebrated for soothing irritation and layering well under makeup, though a minority of users find the finish slightly tacky or insufficient for extremely dry skin without a heavy moisturizer on top.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Soothing for sensitive skin (often mentioned)
- Liked: Layers well (sometimes noted)
- Disliked: Small size (sometimes noted)
- Disliked: Sticky finish (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Insufficient for dry skin (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes ROUND LAB Dokdo Ampoule a great fit for mature skin?

This ampoule is a great fit for mature skin because it deeply hydrates dry areas with glycerin and hydrolyzed hyaluronic acid while strengthening the skin barrier with ceramide NP. It also helps calm the skin and smooth out its texture without any harsh ingredients, making it very gentle.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### Which ingredients make this ampoule a good fit for mature skin?

This ampoule is a great fit for mature skin due to hydrolyzed hyaluronic acid and glycerin, which draw moisture into the dry areas, and ceramide NP, which helps repair and strengthen the skin barrier. These ingredients work together to keep the skin feeling soft and deeply hydrated.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### What does Hydrolyzed Hyaluronic Acid do for mature skin?

Hydrolyzed hyaluronic acid helps mature skin by significantly boosting skin hydration, improving elasticity, and reducing the look of deep wrinkles. It is unlikely to cause irritation, making it a well-suited choice for keeping dry and aging skin looking smooth.
Sources: [Colloids and Surfaces. B, Biointerfaces, 2022](https://pubmed.ncbi.nlm.nih.gov/36279763/)

### What does Hydrolyzed Collagen do for mature skin?

Hydrolyzed collagen helps reduce wrinkles and improves skin elasticity and moisture in mature skin. Regular intake supports skin density and smoothness while helping to prevent the breakdown of natural collagen.
Sources: [International Journal of Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33742704/), [Nutrients, 2023](https://pubmed.ncbi.nlm.nih.gov/37432180/)

### Where does this ampoule go in a skincare routine for mature skin?

This treatment goes in your evening routine, applied after cleansing and before your moisturizer. Putting it in the evening keeps things simple and adds safety around sun exposure, though some treatments can also be used in the morning.

### Can I use this ampoule with retinol, and in what order?

You can use this ampoule with retinol by applying it before your retinol product to help keep mature skin comfortable and hydrated. Using a barrier-supporting moisturizer alongside retinoids is unlikely to cause irritation and may help improve your skin's tolerance.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/)

### How often should I use this ampoule?

You can use this ampoule in the evening as part of your routine. Daily application helps keep mature skin well-hydrated and supports the skin barrier.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this ampoule clog pores, cause breakouts or purging for mature skin?

This ampoule is unlikely to cause breakouts or clog pores for mature skin because its safety profile is excellent and it lacks harsh ingredients. Soothing components like panthenol and ceramides help keep the skin calm and comfortable.

### Can I use this ampoule around the eyes or on my body?

Yes, you can use this moisturizing treatment around your eyes and on your body, as its gentle, hydrating formula works well across different skin thicknesses. It is unlikely to cause irritation and helps keep these delicate areas smooth and well-moisturized.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this ampoule fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/mature-skin) — Average fit — $19.99 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/mature-skin) — Average fit — $22.25 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/mature-skin) — Average fit — $24.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

- Amazon.com: $20.88 (https://www.amazon.com/dp/B08QRPCFL8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Dipropylene Glycol, Propanediol, 1,2-Hexanediol, Sea Water, Hydrolyzed Hyaluronic Acid, Hydrolyzed Collagen, Panthenol, Chondrus Crispus Extract, Saccharum Officinarum Extract, Tromethamine, Ethylhexylglycerin, Caprylic Capric Triglyceride, Betaine, Dipotassium Glycyrrhizate, Glyceryl Glucoside, Hydrogenated Lecithin, Ceramide Np, Tocopherol, Carbomer, Xanthan Gum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/round-lab/1025-dokdo-ampoule/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- France: https://lovi.care/skincare/fr/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/round-lab/1025-dokdo-ampoule/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/round-lab/1025-dokdo-ampoule/for/mature-skin