# Prequel Barrier Therapy Skin Protectant Cream for sensitive skin

**Lovi Fit: Superior fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Prequel](https://lovi.care/skincare/brands/prequel)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best products for sensitive skin.

## Why this fit

- Excellent for your normal skin, this product's oat and ceramides provide superior barrier repair and emollient action, directly addressing your concerns of redness and irritation.
- The inclusion of allantoin further soothes and protects your skin barrier, enhancing resilience and comfort.
- This formula is exceptionally safe for your sensitive skin, featuring a gentle composition free from harsh irritants and enriched with calming agents.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin): Superior (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Oat, Multi-Ceramides, Allantoin, Adenosine

## What the research says

- Application of Body Lotion for 5 weeks on cosmetic dry skin improved barrier properties, increased levels of cholesterol, ceramides, and long-chain fatty acids, increased beneficial skin bacteria, and enhanced microbiome functional potential compared to baseline. ([Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/))
- A topical gel containing chitosan, chlorhexidine, allantoin, and dexpanthenol significantly reduced postoperative pain, trismus, swelling, and analgesic consumption, while improving wound healing after third molar surgery compared to a placebo. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2020](https://pubmed.ncbi.nlm.nih.gov/32683390/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- Topical gel containing chitosan, 0.2% chlorhexidine, allantoin and dexpanthenol did not improve postoperative comfort regarding swelling and pain, but improved the wound's aesthetic appearance following impacted lower third molar extraction compared to no gel. ([Medicina Oral, Patologia Oral Y Cirugia Bucal, 2016](https://pubmed.ncbi.nlm.nih.gov/27475700/))
- An overnight patch containing Allium cepa extract and allantoin safely promotes scar healing after dermatologic surgery, resulting in significantly greater reductions in observer- and patient-assessed POSAS scores compared to no treatment. ([Aesthetic Plastic Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29948103/))
- Prophylactic application of a topical scar gel containing Allium cepae extract, allantoin, and heparin significantly improves patient-assessed scar color, stiffness, and irregularity compared to no treatment in women following a cesarean section. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/24509969/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))

## What reviewers say

While the vast majority find it deeply hydrating and an excellent value for the size, a subset of users reported burning sensations or breakouts, and the product faced a significant recall in 2024 due to contamination concerns.

- Liked: Great value (often mentioned)
- Liked: Non-greasy texture (often mentioned)
- Liked: Versatile use (sometimes noted)
- Disliked: Availability issues (sometimes noted)
- Disliked: Burning sensation (sometimes noted)
- Disliked: Recall history (sometimes noted)
- Disliked: Caused breakouts (rarely noted)

## Questions and answers

### What makes Prequel Barrier Therapy Skin Protectant Cream one of the best fits for sensitive skin?

This cream is one of the best fits for your sensitive skin because its oat, multi-ceramides, and allantoin work together to repair your skin barrier, calm redness, and ease irritation. Its gentle, soothing formula is exceptionally safe and helps make your skin more comfortable and resilient.
Sources: [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### Which ingredients make this cream a good fit for sensitive skin?

Oat, multi-ceramides, and allantoin make this cream a great fit because they help repair your skin barrier and calm redness and irritation. This gentle composition is exceptionally safe and helps keep sensitive skin comfortable and resilient.
Sources: [Scientific Reports, 2022](https://pubmed.ncbi.nlm.nih.gov/35340018/)

### What does Oat do for sensitive skin?

Oat helps calm sensitive skin by soothing irritation and easing discomfort in dry, itchy areas. It also supports skin barrier recovery, making irritated skin feel more comfortable and protected.
Sources: [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/)

### What do Ceramides do for sensitive skin?

Ceramides help calm and strengthen sensitive skin by improving moisture barriers and reducing discomfort. Topical use is well tolerated and may significantly increase skin hydration while easing stinging or sensitive sensations.
Sources: [Archives of Dermatological Research, 2018](https://pubmed.ncbi.nlm.nih.gov/29728858/), [Skin Pharmacology and Physiology, 2026](https://pubmed.ncbi.nlm.nih.gov/41758783/)

### Where does this cream go in a skincare routine for sensitive skin?

This body care cream is used in the evening as the final step to lock in moisture, or anytime your skin feels dry and needs soothing. Its rich blend of oat, multi-ceramides, and allantoin helps repair the skin barrier and keeps redness and irritation calm.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, applying it after your retinol treatment to help calm redness and soothe irritation. Using a barrier-enhancing moisturizer alongside active treatments helps reduce dryness and supports skin comfort.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37276158/)

### How often should I use this cream?

You can use this body care cream daily to help soothe and protect your sensitive skin. Regular application of a gentle moisturizer significantly improves skin barrier function and overall dryness.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can this cream clog pores, cause breakouts or purging for sensitive skin?

This cream is unlikely to clog pores or cause breakouts for your sensitive skin because it features a very gentle and safe composition. Reviewers only rarely report breakouts from using it.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for sensitive skin

- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/sensitive-skin) — Superior fit — $22.00 at Amazon
- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/sensitive-skin) — Superior fit — $15.88 at Amazon
- [COSRX Advanced Snail 92 All in One Cream](https://lovi.care/skincare/p/cosrx/advanced-snail-92-all-in-one-cream/for/sensitive-skin) — Superior fit — $16.50 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $35.98 (https://www.amazon.com/dp/B0GR75MHZ2?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Oat, Water, Carthamus Tinctorius Seed Oil, Cetyl Alcohol, Glycerin, Butyrospermum Parkii Butter, Caprylic Capric Triglyceride, Dimethicone, C10-18 Triglycerides, Allantoin, Adenosine, Cetearyl Olivate, Sorbitan Olivate, Ceramide Ap, Ceramide Eos, Ceramide Eop, Ceramide Np, Ceramide Ns, Cholesterol, Caprooyl Phytosphingosine, Caprooyl Sphingosine, Glycolipids, Sodium Stearoyl Glutamate, Behenic Acid, Ceteareth-25, Glycine Soja Sterols, Hydrogenated Palm Glycerides, Hydrogenated Palm Glycerides Kernel, Carbomer, Phenoxyethanol, Ethylhexylglycerin, Tocopheryl Acetate, Tetrasodium Glutamate Diacetate, Sodium Hydroxide
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/prequel/barrier-therapy-skin-protectant-cream/for/sensitive-skin