# Peter Thomas Roth PEPTIDE SKINJECTION for skin with dark spots

**Lovi Fit: Average fit for skin with dark spots.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dark-spots

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Peter Thomas Roth](https://lovi.care/skincare/brands/peter-thomas-roth)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with dark spots: hyperpigmentation, sun spots, and uneven skin tone. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for skin with dark spots; other moisturizers fit it better.

## Why this fit

- Offers moderate moisturizing for your normal skin due to glycerin and hyaluronic acid, which hydrate and plump, while squalane provides emollient action. This product provides general skincare benefits like hydration, but these are not specialized for your main goal of pigmentation.
- The formula is highly suitable for normal skin, and the absence of harsh ingredients ensures no risks of irritation.
- The safety profile is excellent, with no risks of irritation for your normal skin due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dark-spots): Average (this page)
- [Mature skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Tetrapeptide-1, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit skin with dark spots better

- Treatment with ascorbyl glucoside-arginine complex lotion significantly decreased pigmentation scores and melanin index while increasing lightness in solar lentigos of Japanese females compared to placebo over 24 weeks. ([International Journal of Molecular Sciences, 2024](https://pubmed.ncbi.nlm.nih.gov/39769217/))

## What reviewers say

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

- Liked: Reduces fine lines (mostly mentioned)
- Liked: Smooths skin texture (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Liked: Reduces eye puffiness (sometimes noted)
- Disliked: Gritty serum texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Drying sensation (rarely noted)
- Disliked: Slow/No results (rarely noted)

## How to apply

- Could be used as part of your AM and PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing it too hard so it absorbs nicely.
- For the best moisture, you can apply it when your skin is slightly damp. This helps your skin stay soft and happy.
- Remember to avoid the eye area when applying. Always do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Peter Thomas Roth Peptide Skinjection work for skin with dark spots?

This product works moderately well for your skin, providing general hydration and plumping with glycerin and hyaluronic acid, though it lacks specialized ingredients for dark spots. It is safe and unlikely to cause irritation, but a product for this skin needs brightening ingredients like niacinamide and targeted actives to better handle pigmentation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this cream a good fit for skin with dark spots?

This cream is an average fit for skin with dark spots because it provides general hydration with glycerin and hyaluronic acid rather than specialized brightening actives. Skin with dark spots needs products that include effective brightening and hydrating ingredients, like niacinamide and hyaluronic acid, to target pigmentation while maintaining moisture.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What does Glycerin do for skin with dark spots?

Glycerin helps keep dry skin hydrated and supports a healthy skin barrier, which makes skin feel soft and smooth. While it does not directly fade dark spots on its own, it is often added to spot-fading products to keep the skin comfortable while other ingredients work.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Acta Dermato-venereologica, 2017](https://pubmed.ncbi.nlm.nih.gov/27349297/)

### What does Tetrapeptide-1 do for skin with dark spots?

Tetrapeptide-1 helps fade dark spots and even out skin tone by targeting the factors that cause excess pigmentation. Using a product of this type on dark spots requires added ingredients that block pigment production and gently brighten the skin.

### Where does this cream go in a skincare routine for skin with dark spots?

This cream goes in your evening routine as a treatment step after cleansing. Dark spots need specialized brightening ingredients like vitamin C or niacinamide to help fade discoloration.

### Can I use this cream with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying it either before or after your retinol to help keep your skin soft and comfortable. This type of product is unlikely to cause irritation and may help support your skin barrier while using stronger treatments. To effectively target dark spots, a product of this type needs brightening ingredients like vitamin C, niacinamide, or alpha arbutin.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [The Journal of Dermatological Treatment, 2016](https://pubmed.ncbi.nlm.nih.gov/26293170/)

### How often should I use this cream?

You can use this moisturizing treatment daily in your evening routine, applying it after cleansing and before your moisturizer. Regular use helps keep your skin hydrated and smooth, though a skincare product for dark spots needs targeted brightening ingredients like vitamin C or niacinamide to specifically address pigmentation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for skin with dark spots?

This cream is unlikely to clog pores or cause breakouts for your skin with dark spots because the formula lacks harsh ingredients and has a very safe profile. Skin with dark spots needs targeted brightening ingredients like vitamin C or niacinamide alongside gentle hydration to fade discoloration.

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its safe formula is unlikely to cause irritation. Products used for these areas typically benefit from gentle hydrators like glycerin and hyaluronic acid to keep thin skin soft and smooth.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for skin with dark spots

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/dark-spots) — High fit — $8.40 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/dark-spots) — High fit — $22.25 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/dark-spots) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dark-spots) — Superior fit — $16.99 at Amazon
- SPF: [Murad City Skin Age Defense Broad Spectrum SPF 50](https://lovi.care/skincare/p/murad/city-skin-age-defense-broad-spectrum-spf-50-pa/for/dark-spots) — Superior fit — $73.00 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dark-spots (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/peter-thomas-roth/peptide-skinjection/for/dark-spots
- Ireland: https://lovi.care/skincare/ie/p/peter-thomas-roth/peptide-skinjection/for/dark-spots
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