# Peter Thomas Roth PEPTIDE SKINJECTION for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Peter Thomas Roth](https://lovi.care/skincare/brands/peter-thomas-roth)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your combination skin, as glycerin and hyaluronic acid provide excellent moisturizing effects, though they are not specialized for oil control.
- Niacinamide is present to help with seboregulation, which is beneficial for your oily shine.
- The product is safe for your combination skin due to the absence of prohibited or harsh ingredients, posing no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/oily-skin): Low
- [Dry skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/oily-acne-prone-skin): Average

## Key ingredients

Glycerin, Tetrapeptide-1, Hyaluronic Acid

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))

## Why other moisturizers fit combination skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## What reviewers say

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

- Liked: Reduces fine lines (mostly mentioned)
- Liked: Smooths skin texture (often mentioned)
- Liked: Hydrating formula (sometimes noted)
- Liked: Reduces eye puffiness (sometimes noted)
- Disliked: Gritty serum texture (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Drying sensation (rarely noted)
- Disliked: Slow/No results (rarely noted)

## How to apply

- Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
- Apply this moisturizer after your cleanser and toner, right before your morning SPF.
- Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
- Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
- Avoid the eye area when applying the moisturizer. Do a patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Peter Thomas Roth Peptide Skinjection work for combination skin?

This moisturizer gives you moderate hydration and helps calm your combination skin safely, but it is not specialized for oil control. To work best for this skin type, a product needs effective hydrating ingredients that balance moisture and control shine without causing extra oiliness, along with skin-repairing components like ceramides.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this moisturizing treatment a good fit for combination skin?

Glycerin and hyaluronic acid help provide good moisture, while niacinamide may help manage oily shine. Because this treatment is only an average fit, combination skin needs products that also control excess oiliness, maintain balance, and include ingredients like ceramides and hyaluronic acid to support the skin barrier.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Tetrapeptide-1 do for combination skin?

Tetrapeptide-1 helps keep combination skin smooth and calm while supporting overall skin health. It is unlikely to cause irritation and works well to maintain a balanced, soft feel across both dry and oily areas.

### Where does this moisturizing treatment go in a skincare routine for combination skin?

This moisturizing treatment goes in the evening routine after cleansing and before moisturizing, though it is only an average fit for combination skin and needs specialized oil-control ingredients to work best for this skin type.

### Can I use this moisturizing treatment with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying the treatment after your retinol once it has absorbed, or before it to help keep your skin calm. Combination skin also needs lightweight hydrators and oil-balancing ingredients like niacinamide to keep the T-zone managed without feeling heavy.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this moisturizing treatment?

You can use this moisturizing treatment in your evening routine, as treatments fit best at night for extra safety and simplicity around sun exposure. Combination skin works best with products that balance hydration with oil-controlling ingredients to manage shiny areas effectively.

### Can this moisturizing treatment clog pores, cause breakouts or purging for combination skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for your combination skin since it is free from harsh ingredients that typically trigger irritation. To fully care for combination skin, a product of this type needs lightweight hydrators and balancing ingredients like niacinamide to keep oily shine under control.

### Can I use this moisturizing treatment around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body because it has a safe makeup that is unlikely to cause irritation. However, combination skin needs products with oil-controlling ingredients for oily zones and deep hydrators for dry areas.

### Is this moisturizing treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/combination-skin) — High fit — $8.40 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/combination-skin) — High fit — $22.25 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/combination-skin) — High fit — $24.40 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/combination-skin) — Superior fit — $14.97 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/peter-thomas-roth/peptide-skinjection/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- France: https://lovi.care/skincare/fr/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
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- Saudi Arabia: https://lovi.care/skincare/sa/p/peter-thomas-roth/peptide-skinjection/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/peter-thomas-roth/peptide-skinjection/for/combination-skin