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Peter Thomas Roth PEPTIDE SKINJECTION for combination skin

Rated by Lovi · Unbiased, science-based skincare AI trained on real user outcomes

Peter Thomas Roth PEPTIDE SKINJECTION

Average

  • HighCombination Skin Fit
  • AverageEffectiveness
  • HighSafety

Works for combination skin; other moisturizers fit it better.

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores and recommendations based on your full skin profile, including your 12D face scan results and any goals or preferences you have, please use the Lovi app.

Page built Nov 8, 2026How the Fit score works

Lovi Assistant explains

  • Offers moderate hydration and soothing benefits for your combination skin, as glycerin and hyaluronic acid provide excellent moisturizing effects, though they are not specialized for oil control.
  • Niacinamide is present to help with seboregulation, which is beneficial for your oily shine.
  • The product is safe for your combination skin due to the absence of prohibited or harsh ingredients, posing no risk of irritation.

How to apply

  • Use this moisturizer in your AM and PM routine every day to control shine. Always pair with SPF in the morning.
  • Apply this moisturizer after your cleanser and toner, right before your morning SPF.
  • Gently press a small amount of the moisturizer into your skin and avoid harsh rubbing. Let it ⏳absorb for a minute.
  • Apply the moisturizer on slightly damp skin to help it lock in moisture better. This keeps your combination skin balanced.
  • Avoid the eye area when applying the moisturizer. Do a patch test before your first use.

People Say

★4.6Overall rating based on 200+ reviews

This product line is highly praised for its effectiveness in softening fine lines and improving skin texture, with many users reporting smoother and more hydrated skin. Some users have noted a gritty texture in the serum and varying results for deep wrinkle reduction.

Highlights

  • Reduces fine lines Mostly Mentioned
    • “Big change in forehead lines”
    • “lines around eyes decreased”
    • “definite reduction in lines”
  • Smooths skin texture Often Mentioned
    • “Skin has never felt so smooth”
    • “makeup goes on smooth”
    • “melts into my skin”
  • Hydrating formula Sometimes Noted
    • “Thick hydrating feel”
    • “skin feels more hydrated”
    • “helps hydrate”
  • Reduces eye puffiness Sometimes Noted
    • “Less puffiness under eyes”
    • “quick relief of puffiness”
    • “noticed less puffiness”
  • Gritty serum texture Sometimes Noted
    • “Lotion has a little grit”
    • “texture is a little gritty”
    • “creamy and a bit gritty”
  • High price point Sometimes Noted
    • “Nearly $100 price tag”
    • “hefty price”
    • “less hefty price”
  • Drying sensation Rarely Noted
    • “A bit drying”
    • “skin did not feel oily”
  • Slow/No results Rarely Noted
    • “Not noticed any reduction”
    • “only been 12 days”
    • “didn't last a week”

Sources: lovi.care, peterthomasroth.com, lovelyskin.com, dermstore.com, reddit.com, and more

Questions and answers

How well does Peter Thomas Roth Peptide Skinjection work for combination skin?

This moisturizer gives you moderate hydration and helps calm your combination skin safely, but it is not specialized for oil control. To work best for this skin type, a product needs effective hydrating ingredients that balance moisture and control shine without causing extra oiliness, along with skin-repairing components like ceramides.

Clinical, Cosmetic and Investigational Dermatology, 2017

Which ingredients make this moisturizing treatment a good fit for combination skin?

Glycerin and hyaluronic acid help provide good moisture, while niacinamide may help manage oily shine. Because this treatment is only an average fit, combination skin needs products that also control excess oiliness, maintain balance, and include ingredients like ceramides and hyaluronic acid to support the skin barrier.

Clinical, Cosmetic and Investigational Dermatology, 2017

What does Glycerin do for combination skin?

Glycerin helps keep combination skin soft and smooth by pulling moisture in and keeping it there. It improves hydration and supports your skin barrier, which is unlikely to cause irritation.

The British Journal of Dermatology, 2008Clinical, Cosmetic and Investigational Dermatology, 2017

What does Tetrapeptide-1 do for combination skin?

Tetrapeptide-1 helps keep combination skin smooth and calm while supporting overall skin health. It is unlikely to cause irritation and works well to maintain a balanced, soft feel across both dry and oily areas.

Where does this moisturizing treatment go in a skincare routine for combination skin?

This moisturizing treatment goes in the evening routine after cleansing and before moisturizing, though it is only an average fit for combination skin and needs specialized oil-control ingredients to work best for this skin type.

Can I use this moisturizing treatment with retinol, and in what order?

You can use this moisturizing treatment with retinol by applying the treatment after your retinol once it has absorbed, or before it to help keep your skin calm. Combination skin also needs lightweight hydrators and oil-balancing ingredients like niacinamide to keep the T-zone managed without feeling heavy.

Cutis, 2006

How often should I use this moisturizing treatment?

You can use this moisturizing treatment in your evening routine, as treatments fit best at night for extra safety and simplicity around sun exposure. Combination skin works best with products that balance hydration with oil-controlling ingredients to manage shiny areas effectively.

Can this moisturizing treatment clog pores, cause breakouts or purging for combination skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for your combination skin since it is free from harsh ingredients that typically trigger irritation. To fully care for combination skin, a product of this type needs lightweight hydrators and balancing ingredients like niacinamide to keep oily shine under control.

Can I use this moisturizing treatment around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body because it has a safe makeup that is unlikely to cause irritation. However, combination skin needs products with oil-controlling ingredients for oily zones and deep hydrators for dry areas.

Is this moisturizing treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

What the research says

  • A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

    Clinical, Cosmetic and Investigational Dermatology, 2017

  • The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

    Journal of Cosmetic Dermatology, 2020

  • Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

    International Journal of Cosmetic Science, 2001

  • Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects.

    Journal of Drugs in Dermatology, 2012

  • Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

    Journal of Drugs in Dermatology, 2011

  • Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

    Clinical Oral Investigations, 2022

  • Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

    BMC Oral Health, 2019

Why other moisturizers fit combination skin better

  • A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions.

    Journal of Cosmetic Dermatology, 2024

Ingredients

Water, Glycerin, Chondrus Crispus Powder, Butylene Glycol, Tetrapeptide-1, Hyaluronic Acid, Allantoin, Trehalose, Caffeine, Squalane, Niacinamide, Adenosine, Tocopheryl Acetate, Calcium Lactate, Opuntia Ficus-Indica Flower Extract, Chondrus Crispus Extract, Chlorphenesin, Ricinus Communis Seed Oil Castor Seed Oil, Potassium Chloride, Dextrin, Sodium Phytate, Caprylyl Glycol, Citric Acid, Ceratonia Siliqua Gum, Xanthan Gum, Peg-60 Hydrogenated Castor Oil, Ultramarines, Chromium Hydroxide Green Ci 77289, Phenoxyethanol

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.

  • Nadia Kapleva, MS

    Nadia Kapleva, MS

    Co-founder, Medical Director

    Cosmetic chemist, cosmetologist, aesthetic products developer

  • Alexey Shagraev, PhD

    Alexey Shagraev, PhD

    Co-founder, CEO and CTO

    PhD in computer science, 3x US patent holder, ex-Google, ex-Yandex

  • Dr. Sofía Perea Pérez, MD, MSc

    Dr. Sofía Perea Pérez, MD, MSc

    Medical Board

    Aesthetic medicine practitioner, MSc in Longevity and Anti-Aging Medicine

  • Aishani Shah, MD

    Aishani Shah, MD

    Medical Board

    Specialist dermatologist, MBBS, MD, IFAAD

  • Asya Zubkova, MS

    Asya Zubkova, MS

    Medical Board

    Cosmetic chemist, SCS, IFSCC member

  • Hanna Kurets, MD

    Hanna Kurets, MD

    Medical Board, Medical Advisor

    Dermatology MD

  • Elina Nazarenko, MD

    Elina Nazarenko, MD

    Medical Board

    Dermatology and diagnostic consultant

  • Victoria Derkova, MS

    Victoria Derkova, MS

    Medical Board

    Cosmetic chemist, cosmetic development technologist

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