# Perricone MD Rebalancing Elixir for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Perricone MD](https://lovi.care/skincare/brands/perricone-md)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Offers excellent hydration for your dry skin, as sodium PCA and glycerin effectively draw moisture in, complemented by the calming and antioxidant properties of cannabidiol and mushroom extracts.
- Annona cherimola fruit extract further supports skin barrier function, enhancing overall comfort and suppleness.
- The formulation is safe for your dry skin, with no risk of irritation due to the absence of harsh ingredients and the inclusion of soothing components like cannabidiol and mushroom extracts.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/sensitive-skin): Superior
- [Acne-prone skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/oily-acne-prone-skin): High

## Key ingredients

Cannabidiol, Mushroom Complex, Cherimoya Fruit Extract, Capryloyl Glycine, Sodium Pca

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of an anti-aging gel containing EPA and CBD reduced inflammatory agents, decreased crow's feet and fine line wrinkle volume, reduced the subepidermal low-echogenic band by 8.8%, and increased skin hydration by 31.2% and elasticity by 25.6% in 33 participants over 56 days compared to baseline. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/))
- Topical nano-cannabidiol cream reduced UV-A-induced epidermal hyperplasia, nuclear DNA base lesions, and mitochondrial DNA deletions compared with vehicle in nineteen participants. ([Journal of the American Academy of Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/39025264/))
- Daily application of a novel retinol and cannabidiol combination topical improved global skin quality across 13 domains, including visible pores, dehydration, surface roughness, and static and dynamic wrinkles, in 10 patients with facial skin imperfections. ([Aesthetic Surgery Journal. Open Forum, 2022](https://pubmed.ncbi.nlm.nih.gov/35274096/))
- Topical application of carboxymethylcellulose/chitosan hydrogel loaded with cannabidiol reduced inflammation and increased collagen production in radiation-combined wound skin injury in mice. ([Phytomedicine, 2025](https://pubmed.ncbi.nlm.nih.gov/40318533/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))
- Topical application of a formulation containing capryloyl glycine 4% significantly decreased hair density, median hair length, and terminal hair density on the forearms compared to placebo in female patients with hypertrichosis after 120 days. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33347705/))
- A novel natural carrier-free assembled gel composed of sodium pyrrolidone carboxylate and baicalin alleviates UVB-induced skin photodamage by scavenging reactive oxygen species, protecting mitochondria, restoring oxidative homeostasis, inhibiting inflammatory responses, and regulating collagen-related proteins. ([Biomaterials Advances, 2026](https://pubmed.ncbi.nlm.nih.gov/41129958/))

## What reviewers say

Most users find it provides lightweight hydration that absorbs quickly without feeling heavy, leading to improved skin balance and texture. A moderate number of users feel the product is too expensive for the results, and a low number dislike the natural scent or do not see dramatic anti-aging effects.

- Liked: Soothes sensitive skin (mostly mentioned)
- Liked: Lightweight hydration (often mentioned)
- Liked: Good for layering (sometimes noted)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Expensive for results (sometimes noted)
- Disliked: Not a miracle worker (rarely noted)
- Disliked: Product availability issues (rarely noted)
- Disliked: Unpleasant natural scent (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Perricone MD Rebalancing Elixir a great fit for dry skin?

Perricone MD Rebalancing Elixir is a great fit because ingredients like sodium PCA and glycerin draw moisture in to provide deep hydration for dry skin, while cannabidiol, mushroom extracts, and cherimoya fruit extract help calm the skin and support its protective barrier. This gentle formula is also unlikely to cause irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/)

### Which ingredients make this toner a good fit for dry skin?

Sodium PCA and glycerin make this toner a great fit by drawing in moisture, while cannabidiol, mushroom extracts, and cherimoya fruit extract help calm and comfort dry skin. These ingredients provide excellent hydration and support the skin barrier without any harsh additives.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/)

### What does Cannabidiol do for dry skin?

Cannabidiol helps keep dry skin hydrated and smooth while calming irritation. Topical products containing it improve moisture levels and support the skin barrier, making them very useful for managing dryness and discomfort.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/), [Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/41178006/)

### What does Mushroom Complex do for dry skin?

Mushroom Complex helps dry skin by boosting moisture levels and smoothing out rough texture. It contains ingredients that support the skin barrier to keep your face feeling soft and hydrated.
Sources: [Frontiers in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38887673/), [Molecules, 2026](https://pubmed.ncbi.nlm.nih.gov/41599327/)

### Where does this toner go in a skincare routine for dry skin?

This product is used as an evening treatment step after cleansing and before moisturizing. A consistent daily routine helps improve hydration and reduces visual dryness in dry skin.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this toner with retinol, and in what order?

This treatment is a great fit for your dry skin, offering deep hydration and calming comfort. You can use it alongside your retinol by applying this product before your retinol, as its soothing ingredients help keep your skin calm and moisturized.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this toner?

This product is a treatment rather than a toner, so it fits best in your evening routine. You may apply it in the PM as part of your regular steps to help hydrate and calm dry skin.
Sources: [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/)

### Can this toner clog pores, cause breakouts or purging for dry skin?

Perricone MD Rebalancing Elixir is unlikely to clog pores or cause breakouts for dry skin, as its hydrating and soothing ingredients are gentle and safe. The formula helps maintain comfortable moisture levels without heavy oils that typically block pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37264742/)

### Is this toner fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — $16.75 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — $53.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — $19.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — $19.99 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — $16.99 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — $22.00 at Amazon

## Where to buy

- Amazon.com: $99.00 (https://www.amazon.com/dp/B0G6HLB48Z?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, 1,2-Hexanediol, Sodium Pca, Triethyl Citrate, Propanediol, Capryloyl Glycine, Glycerin, Annona Cherimola Fruit Extract, Cannabidiol, Ganoderma Lucidum Stem Extract Mushroom Stem Extract, Grifola Frondosa Fruiting Body Extract, Sodium Bicarbonate, Caprylhydroxamic Acid, Sodium Hydroxide, Citric Acid, Cannabis Sativa Glycereth-8 Esters Seed Oil, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Citrate, Lentinus Edodes Mycelium Extract, Sodium Dehydroacetate, Phenylpropanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/rebalancing-elixir/for/dry-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/rebalancing-elixir/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/rebalancing-elixir/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/rebalancing-elixir/for/dry-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/rebalancing-elixir/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/rebalancing-elixir/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/rebalancing-elixir/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/rebalancing-elixir/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/perricone-md/rebalancing-elixir/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/rebalancing-elixir/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/rebalancing-elixir/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/rebalancing-elixir/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/rebalancing-elixir/for/dry-skin