# Perricone MD Nutritive Cleanser for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Perricone MD](https://lovi.care/skincare/brands/perricone-md)
Category: [Cleansers](https://lovi.care/skincare/best/cleansers)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other cleansers fit it better.

## Why this fit

- Offers moderate cleansing for normal skin due to Sodium Laureth Sulfate and Lauryl Glucoside effectively removing impurities, though it lacks specific ingredients to target your redness and irritation concerns.
- Citric Acid provides mild exfoliation suitable for normal skin, but the formula could benefit from additional hydrating components for a more balanced feel.
- The product is safe for your sensitive skin as it contains no harsh or prohibited ingredients, minimizing the risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/dry-skin): Low
- [Combination skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/dry-sensitive-skin): Low
- [Oily acne-prone skin](https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/oily-acne-prone-skin): Average

## Key ingredients

Alpha Lipoic Acid, Copper Gluconate, Zinc Gluconate, Dimethyl Mea Dmae, Aha Complex

## What the research says

- Formulating sodium laureth sulphate with sodium laureth carboxylate and lauryl glucoside prevented significant decreases in cutaneous capacitance and reduced erythema and dryness in healthy volunteers compared to unsupplemented sodium laureth sulphate. ([International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/))
- Topical application of 1-1.5% glycolic acid suppresses UVB-induced inflammation by modulating NF-κB signaling pathways in human keratinocytes and mouse dorsal skin. ([Journal of Dermatological Science, 2017](https://pubmed.ncbi.nlm.nih.gov/28330776/))
- Topical 30% P407 gel loaded with ALA cubosomes reduced facial lines, nearly resolved fine lines in the periorbital and upper lip areas, and improved skin color and texture without irritation or peeling in volunteers. ([European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/))
- Application of 5% cubosomal alpha lipoic acid gel twice daily for 6 months significantly improved global aesthetic scores and increased epidermal thickness compared to placebo in 20 aging female faces. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/27873449/))
- Treatment with a cream containing 5% alpha-lipoic acid for 12 weeks reduces skin roughness by an average of 50.8% compared to 40.7% with placebo in women with photoaged facial skin. ([The British Journal of Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/14616378/))
- Zinc gluconate induced alpha2, alpha3, alphaV, and alpha6 integrins, copper gluconate induced alpha2, alpha6, and beta1, and manganese gluconate induced most studied integrins in cultured keratinocytes. ([The British Journal of Dermatology, 1999](https://pubmed.ncbi.nlm.nih.gov/10215764/))
- A dermocosmetic cream containing Punica granatum Pericarp extract, Salicylic acid, Niacinamide, Zinc gluconate, and Aqua Posae Filiformis significantly decreased inflammatory, non-inflammatory, and total lesion counts in subjects with mild to moderate acne compared to untreated hemi-faces after 15 days. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41487026/))
- Daily use of a deep cleansing gel containing salicylic acid 2%, zinc gluconate 0.2% and lipohydroxy acid 0.05% significantly reduced total lesion count by 56.3% after 84 days in 35 subjects with mild to moderate truncal acne. ([Clinical, Cosmetic and Investigational Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/36698447/))
- Different strains of Propionibacterium acnes modulate cutaneous innate immunity with varying pro-inflammatory potentials, with P. acnes type III showing the highest and P. avidum the weakest, and zinc gluconate down-regulates the expression of most induced immune markers. ([Experimental Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23947673/))
- Daily application of 3% DMAE facial gel for 16 weeks safely and efficaciously mitigates forehead lines and periorbital fine wrinkles, improves lip shape and fullness and overall aging skin appearance, and increases skin firmness compared to placebo. ([American Journal of Clinical Dermatology, 2005](https://pubmed.ncbi.nlm.nih.gov/15675889/))
- A gel containing 3% 2-dimethylaminoethanol (DMAE) increased skin firmness, demonstrated by increased shear wave velocity in 30 volunteers compared to a formulation without DMAE. ([Skin Research and Technology, 2002](https://pubmed.ncbi.nlm.nih.gov/12236885/))
- A DMAE-based formulation increased dermal and collagen fiber thickness in hairless mice and enhanced stratum corneum water content in human forearm skin compared to control formulations, without significantly modifying mechanical properties. ([Die Pharmazie, 2009](https://pubmed.ncbi.nlm.nih.gov/20095140/))

## Why other cleansers fit sensitive skin better

- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))

## What reviewers say

Based on a very large amount of data, users frequently praise this gel cleanser for its ability to thoroughly remove makeup and oil without stripping the skin's natural moisture barrier, making it a favorite for those with normal to dry skin. Many report softer, brighter, and more radiant skin after use, though a notable minority of users express dissatisfaction with the product's strong fragrance and the recent packaging change from a glass bottle to a plastic tube.

- Liked: Gentle and non-drying (mostly mentioned)
- Liked: Effective makeup remover (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Liked: Improves skin texture (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Eye irritation (rarely noted)
- Disliked: High price point (rarely noted)

## How to apply

- Use your cleanser in the AM and PM routines every day. Start using it daily since your sensitive skin needs gentle care.
- Apply this first in your morning and evening skincare routine before toner and moisturizer. This clears away dirt without upsetting your skin.
- Gently massage a small amount onto your face using soft circles. Avoid any rough rubbing to keep redness away.
- Apply the cleanser on slightly damp skin to help it wash away impurities softly. Clean skin feels fresh and comfortable afterwards.
- Avoid getting the cleanser in your eyes and do a quick patch test before first use. Rinse thoroughly with lukewarm water.
- Video: https://storage.pora.ai/6a08416bd9315041c09c72f61cf27cc1.mp4

## Questions and answers

### How well does Perricone MD Nutritive Cleanser work for sensitive skin?

This cleanser is an average fit because while it cleans without harsh ingredients, it lacks specific components to target redness and irritation and could use extra hydrating ingredients for a more balanced feel. Cleansers for sensitive skin need soothing ingredients that calm redness and irritation, along with moisturizing agents to keep skin comfortable.
Sources: [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Which ingredients make this cleanser a good fit for sensitive skin?

This cleanser is a safe fit for sensitive skin because it contains no harsh ingredients, minimizing the risk of irritation. To work best for this skin, a cleanser of this type needs soothing ingredients like amino acids and aloe, along with hydrating components for a more balanced feel.

### What does Alpha Lipoic Acid do for sensitive skin?

Alpha lipoic acid may not be the best fit for sensitive skin on its own, as it can sometimes cause irritation or skin disorders. A product for sensitive skin needs soothing, calming ingredients and gentle antioxidants that protect without causing redness or discomfort.
Sources: [Clinical Nutrition, 2021](https://pubmed.ncbi.nlm.nih.gov/32778460/)

### What does Copper Gluconate do for sensitive skin?

Copper gluconate helps calm and soothe sensitive skin while supporting a healthy skin barrier. It is unlikely to cause irritation and works well to keep skin feeling soft and balanced.

### Where does this cleanser go in a skincare routine for sensitive skin?

This cleanser is used both morning and night as a basic cleansing step in your daily routine. It is safe for sensitive skin as it contains no harsh or prohibited ingredients, though a product of this type for sensitive skin ultimately needs extra calming and hydrating ingredients to soothe redness and irritation.

### Can I use this cleanser with retinol, and in what order?

You can use this cleanser in your routine, but sensitive skin needs a cleanser that includes extra hydrating components and soothing ingredients to help calm redness and irritation when using retinol.

### How often should I use this cleanser?

You can use this cleanser daily in the morning and evening as part of your routine. It is safe for your sensitive skin because it contains no harsh or prohibited ingredients, minimizing the risk of irritation.

### Can this cleanser clog pores, cause breakouts or purging for sensitive skin?

This cleanser is unlikely to clog pores or cause breakouts for sensitive skin since it contains no heavy oils or pore-clogging ingredients. A cleanser for this skin needs gentle cleansing agents along with soothing and hydrating components to keep skin calm and balanced.

### Can I use this cleanser around the eyes or on my body?

You can use this cleanser on your body, but the thin skin around the eyes may require extra caution since the formula lacks specific soothing and hydrating ingredients to target redness and irritation. Body and eye care products of this type often need added moisturizing components and gentle, barrier-protecting ingredients to keep sensitive areas balanced and comfortable.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [International Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24617572/)

### Is this cleanser fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (parfum).

## Alternatives for sensitive skin

- [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- [IS Clinical Cleansing Complex](https://lovi.care/skincare/p/is-clinical/cleansing-complex/for/sensitive-skin) — Superior fit — $49.00 at Amazon
- [Missha Super Aqua Ultra Hyalron Cleansing Foam](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-cleansing-foam/for/sensitive-skin) — High fit — $9.20 at Amazon

## Pairs well with

- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon
- Pre-Cleanser: [MISSHA Ultra Hyalon Cleansing Cream](https://lovi.care/skincare/p/missha/ultra-hyalon-cleansing-cream/for/sensitive-skin) — Superior fit — $21.70 at Amazon

## Where to buy

- Amazon.com: $39.00 (https://www.amazon.com/dp/B084RSMQ45?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Sodium Laureth Sulfate, Lauryl Glucoside, Cocamidopropyl Betaine, Ppg-2 Hydroxyethyl Coco Isostearamide, Dimethyl Mea Dmae, Citric Acid, Sodium Chloride, Thioctic Acid Alpha-Lipoic Acid, Disodium Edta, Parfum, Benzophenone-4, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate, Methylchloroisothiazolinone, Methylisothiazolinone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/perricone-md/nutritive-cleanser/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/perricone-md/nutritive-cleanser/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/perricone-md/nutritive-cleanser/for/sensitive-skin