PCA Skin Smoothing Toner for acne-prone skin

How to apply

Questions and answers

What the research says

• Daily treatment with a facial serum containing multiple acids reduced post-inflammatory hyperchromia lesion grade and number by 29.4% at 56 days, and decreased skin oiliness by 30.7% at 7 days in Brazilian patients with acne vulgaris.

  Journal of Cosmetic Dermatology, 2021

• A novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid showed similar tolerance and efficacy compared with clindamycin 1% and benzoyl peroxide 5% gel in subjects with acne vulgaris.

  Journal of Drugs in Dermatology, 2013

• A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo.

  Clinical Pharmacology, 2018

• Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin.

  Cutis, 2004

• Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties.

  Journal of the American Academy of Dermatology, 1992

• A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins.

  The Journal of Clinical and Aesthetic Dermatology, 2020

• Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief.

  Plastic and Reconstructive Surgery, 2018

• Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo.

  Journal of Alternative and Complementary Medicine, 2010

• Formulations containing 0.10%, 0.25%, and 0.50% freeze-dried Aloe vera extract increased stratum corneum water content compared with the vehicle in 20 female subjects, while transepidermal water loss was not modified.

  Skin Research and Technology, 2006

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol.

  Journal of Cosmetic Dermatology, 2020

• Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant.

  International Journal of Cosmetic Science, 2001

• Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation.

  International Journal of Biological Macromolecules, 2020

• A carboxymethyl cellulose-based hydrogel film loaded with berberine reduced keratinocyte hyperproliferation by 25% and controlled oxidative stress and inflammation markers in vitro.

  Carbohydrate Polymers, 2022

• Berberine dose-dependently inhibited basal and TPA-induced expression and activity of MMP-9, and suppressed TPA-induced IL-6 expression in normal human keratinocytes.

  Phytomedicine, 2008

• Transgenic cucumber expressing poly-γ-glutamic acid synthesis genes increased water content by 6-14%, reduced water loss by 11-12%, decreased facial wrinkles and roughness by 19.58% and 24.97%, decreased skin melanin by 5.27%, and improved facial elasticity in human skin and zebrafish compared to controls.

  International Journal of Biological Macromolecules, 2024

• Copper Oxide nanoparticles synthesized using cucumber extract exhibited antibacterial, antifungal, UV protection, and reactive-oxygen species inhibition properties with low cellular toxicity and skin-rejuvenating effects when incorporated into skin cream.

  Endocrine, Metabolic & Immune Disorders Drug Targets, 2021

• Topical treatment with Holothuria parva extract gel showed significant wound contraction compared to the negative control in full-thickness wounded rats.

  The International Journal of Lower Extremity Wounds, 2024

Ingredients

Water, Lactic Acid, Citric Acid, Glycerin, Aloe Barbadensis Leaf Juice, Hydrastis Canadensis Extract, Cucumis Sativus Fruit Extract, Salvia Officinalis Leaf Extract, Calendula Officinalis Flower Extract, Arctium Lappa Root Extract, Paullinia Cupana Seed Extract, Hedera Helix Stem Extract Leaf, Tetrasodium Edta

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.