# Paula's Choice Super Antioxidant Concentrate Serum for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: Average · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Paula's Choice](https://lovi.care/skincare/brands/paula-s-choice)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Offers high suitability for your normal skin, as retinol and adenosine effectively target wrinkles and fine lines by promoting collagen production and skin renewal.
- The serum provides excellent antioxidant protection and moisturization with tocopherol and tetrahexyldecyl ascorbate, enhancing barrier resilience.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing agents like Bisabolol and Chamomilla Recutita Flower Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/oily-skin): Caution
- [Dry skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/combination-skin): Low
- [Sensitive skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/oily-acne-prone-skin): Low

## Key ingredients

Retinol, Tetrahexyldecyl Ascorbate, Tocopherol, Bisabolol, Astaxanthin

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))
- Application of an alpha-bisabolol-containing cream produced a significant skin-lightening effect in pigmented skin compared to a vehicle control in the majority of female subjects after 8 weeks. ([International Journal of Cosmetic Science, 2010](https://pubmed.ncbi.nlm.nih.gov/20642768/))
- The combination of allantoin, bisabolol, D-panthenol and dipotassium glycyrrhizinate reduces UVB-induced PGE2, inflammatory cytokines, and mitochondrial superoxide in human epidermal keratinocytes. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38433250/))
- Oral astaxanthin supplementation significantly restored moisture content and improved elasticity but did not significantly decrease wrinkle depth compared to placebo in humans. ([Nutrients, 2021](https://pubmed.ncbi.nlm.nih.gov/34578794/))
- Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss. ([Acta Biochimica Polonica, 2012](https://pubmed.ncbi.nlm.nih.gov/22428137/))
- Twice-daily application of a novel topical antioxidant formulation safe, well-tolerated, and effective in improving overall skin quality, fine lines, wrinkles, radiance, and hyperpigmentation in 32 healthy female subjects over 12 weeks. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37608511/))

## What reviewers say

Based on limited data, this viscous, silicone-based serum is highly praised by users with dry or mature skin for its deep hydration and ability to create a smooth, protective barrier. Many report brighter, calmer skin and improved texture. Users with combination or oily skin frequently find the finish too heavy or greasy.

- Liked: Deep hydration protection (often mentioned)
- Disliked: Greasy or shiny finish (often mentioned)
- Liked: Improves texture tone (sometimes noted)
- Liked: Silky application (sometimes noted)
- Liked: Soothing sensitive skin (sometimes noted)
- Disliked: Slow absorption (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Paula's Choice Super Antioxidant Concentrate Serum a great fit for mature skin?

This serum is a great fit for mature skin because retinol and adenosine help smooth out fine lines by encouraging skin renewal. It also delivers rich antioxidant protection and moisture with vitamins C and E to strengthen your skin barrier, while soothing ingredients keep irritation unlikely.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this serum a good fit for mature skin?

This serum is a great fit for mature skin because retinol and adenosine help smooth out wrinkles and fine lines by encouraging skin renewal. Additionally, ingredients like tocopherol and tetrahexyldecyl ascorbate provide strong antioxidant protection while keeping the skin feeling soft and moisturized.

### What does Retinol do for mature skin?

Retinol helps smooth out fine lines and wrinkles while improving overall skin thickness and firmness over time. It may also cause temporary dryness, scaling, or stinging as your skin gets used to it.
Sources: [The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/)

### What does Vitamin C do for mature skin?

Vitamin C helps smooth out wrinkles, fade dark spots, and calm redness on mature skin. It also boosts collagen production to make skin firmer and protects against everyday environmental stress.
Sources: [The Journal of Clinical and Aesthetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/29104718/), [Dermatologic Surgery, 2002](https://pubmed.ncbi.nlm.nih.gov/11896774/)

### Where does this serum go in a skincare routine for mature skin?

This serum goes in your evening routine after cleansing and before your moisturizer. Treatments with active ingredients are placed at night for simplicity and extra safety around sun exposure.

### Can I use this serum with niacinamide, and in what order?

Yes, you can use this serum with niacinamide by applying niacinamide first and then following with this treatment. Both ingredients work well together to smooth fine lines and keep your skin feeling soft and protected.

### How often should I use this serum?

You can use this serum in your evening routine. Using it daily helps smooth fine lines and protects mature skin while keeping irritation very unlikely.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this serum clog pores, cause breakouts or purging for mature skin?

This serum is unlikely to cause breakouts for mature skin, as it features a low risk of clogged pores in reviews and includes soothing ingredients like bisabolol and chamomile. However, because it contains retinol which speeds up skin renewal, you may experience mild initial purging.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around the eyes, but keep it away from the lash line. Its gentle formula helps smooth fine lines while being very safe for delicate areas.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/)

### Is this serum fragrance-free and alcohol-free?

It has no fragrance and contains drying alcohol (sd alcohol 40 alcohol denat).

## Alternatives for mature skin

- [Revision Skincare Hydrating Serum](https://lovi.care/skincare/p/revision-skincare/hydrating-serum/for/mature-skin) — High fit — $109.00 at Amazon
- [innisfree Green Tea Seed Hyaluronic Acid Hydrating Serum](https://lovi.care/skincare/p/innisfree/green-tea-seed-hyaluronic-acid-hydrating-serum/for/mature-skin) — High fit — $30.00 at Amazon
- [su:m37º Secret Essence Double Concentrate](https://lovi.care/skincare/p/su-m37o/secret-essence-double-concentrate/for/mature-skin) — High fit — $29.99 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

- Amazon.com: $53.00 (https://www.amazon.com/dp/B00EEGEI7C?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Cyclopentasiloxane, Dimethicone, C12-15 Alkyl Benzoate, Olea Europaea Oil Fruit Olive Oil Fruit, Tocopherol, Retinol, Tetrahexyldecyl Ascorbate, Bisabolol, Tocotrienols, Adenosine, Tetrahydrodiferuloylmethane, Tetrahydrodemethoxydiferuloylmethane, Tetrahydrobisdemethoxydiferuloylmethane, Camellia Oleifera Leaf Extract Camellia Sinensis Leaf Extract, Vitis Vinifera Seed Oil Grape Seed Oil, Chamomilla Recutita Flower Extract Matricaria Flower Extract, Arctostaphylos Uva-Ursi Leaf Extract, Stearyl Dimethicone, Astaxanthin, Glycine Soja Oil Soybean Oil, Vitis Vinifera Seed Extract Grape Seed Extract, Oenothera Biennis Oil, Cranberry Seed Oil, Rubus Idaeus Seed Oil Raspberry Seed Oil, Vaccinium Myrtillus Seed Oil, Palm Oil, Sd Alcohol 40 Alcohol Denat
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/super-antioxidant-concentrate-serum/for/mature-skin