# Paula's Choice Peptide Booster for sensitive skin

**Lovi Fit: Average fit for sensitive skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Paula's Choice](https://lovi.care/skincare/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with sensitive skin: redness, stinging, and reactions to new products. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for your normal skin, as multiple peptides and glycerin work to stimulate collagen and provide hydration, addressing your concerns of redness and irritation by supporting skin repair.
- Dipotassium glycyrrhizate and adenosine further soothe and calm the skin, contributing to a more comfortable complexion.
- The product is safe for your sensitive skin, containing no harsh ingredients and including soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/sensitive-skin): Average (this page)
- [Acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/oily-acne-prone-skin): High

## Key ingredients

Peptides, Complex Amino Acid, Glycerin, Panax Ginseng Root Extract, Psidium Guajava Fruit Extract

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Dipotassium glycyrrhizinate-loaded hydroxypropyl chitosan and poly(N-isopropylacrylamide) hydrogels applied to wounds in a mouse full-thickness skin defect model resulted in rapid wound closure, efficient tissue remolding, collagen deposition, and decreased inflammation compared to commercial Tegaderm film and 3M dressing controls. ([Acta Biomaterialia, 2022](https://pubmed.ncbi.nlm.nih.gov/35245682/))
- An amino acid complex formulated in a Skin Recovery System reduced skin irritation and redness while accelerating the skin repair process in 37 subjects. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Enzyme-modified ginseng extract cream significantly reduced the global photo-damage score and various roughness measures including total roughness, smoothness depth, and arithmetic roughness average compared to placebo in 23 human subjects. ([Rejuvenation Research, 2015](https://pubmed.ncbi.nlm.nih.gov/25867599/))
- A red ginseng hydrogel formulation with 1,2-hexanediol promoted selective growth of Staphylococcus epidermidis and decreased Cutibacterium acnes in 20 female subjects. ([Journal of Ginseng Research, 2022](https://pubmed.ncbi.nlm.nih.gov/35509819/))
- A 1% fermented black ginseng cream significantly reduced eye wrinkles and brightened skin color in twenty-three human subjects compared to control cream and baseline. ([Journal of Toxicology and Environmental Health. Part A, 2020](https://pubmed.ncbi.nlm.nih.gov/32564709/))
- A toner with 6% guava extract significantly reduced skin oiliness on the forehead and nose compared to the base toner in 21 volunteers over 28 days. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30964238/))
- Pre-incubation with guava crude extract significantly decreased apoptotic and dead cells and markers of oxidative damage while improving antioxidant enzyme activity in human dermal fibroblasts subjected to AAPH-mediated oxidative stress, compared to cells subjected to stress without prior pre-incubation. ([Plant Foods for Human Nutrition, 2018](https://pubmed.ncbi.nlm.nih.gov/29455277/))

## What reviewers say

Based on a very large amount of data, users with dry, dull, and aging skin report that this booster effectively plumps, hydrates, and improves overall skin elasticity. Consistent use leads to visibly firmer skin and a reduction in fine lines and wrinkles. Some users feel the results take time to manifest.

- Liked: Plumps and hydrates (mostly mentioned)
- Liked: Firms and smooths (often mentioned)
- Liked: Layers seamlessly (often mentioned)
- Liked: Lightweight, fast-absorbing (often mentioned)
- Disliked: High price point (sometimes noted)
- Disliked: Poor dropper packaging (sometimes noted)
- Disliked: Slow, subtle results (rarely noted)

## How to apply

- Use your serum in the PM routine, starting 3 times a week before building up to daily use if your skin is happy.
- Apply the serum after cleansing and toning, but before putting on your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏱ for it to soak in.
- Since your skin is sensitive and easily irritated, apply the serum on completely dry skin to help keep it calm.
- Always do a patch test before your first use and avoid getting the serum too close to your eyes .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Paula's Choice Peptide Booster work for sensitive skin?

This product works for sensitive skin, though other treatments fit it better. It offers moderate benefits by using peptides and glycerin to hydrate and help calm redness and irritation. A product of this type needs soothing ingredients like niacinamide and snail secretion filtrate to best fit sensitive skin.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this booster a good fit for sensitive skin?

This booster suits your sensitive skin because glycerin, multiple peptides, and amino acids help calm redness, support skin repair, and keep your complexion comfortable. To fit this skin type best, products also need soothing ingredients like niacinamide or snail secretion filtrate alongside strong antioxidants without any allergens.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Peptides do for sensitive skin?

Peptides help support the skin barrier and improve the feel of sensitive skin by encouraging firmness and a smooth look. When paired with soothing and hydrating ingredients, peptide products are generally well tolerated and unlikely to cause irritation.
Sources: [Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/), [Journal of Biomedical Materials Research, 1998](https://pubmed.ncbi.nlm.nih.gov/9457557/)

### What do Amino Acids do for sensitive skin?

Amino acids help calm sensitive skin by reducing redness and irritation while speeding up the skin repair process. They are unlikely to cause allergy or irritation, making them very gentle for easily upset skin.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/), [International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33561977/)

### Where does this booster go in a skincare routine for sensitive skin?

This treatment goes in the evening routine after your soothing toner and before your moisturizer. A product of this type needs calming ingredients and gentle hydrators to soothe redness and support sensitive skin.

### Can I use this booster with retinol, and in what order?

You can use this booster with retinol by applying the booster first and following with your retinol. Because this product is an average fit for your sensitive skin, a better option for this skin type needs calming plant extracts, amino acids, and gentle hydrators to soothe redness without irritation.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### How often should I use this booster?

You can use this treatment in your evening routine, applying it after your toner and before your moisturizer. This product works well for sensitive skin, but this skin type needs products that focus heavily on gentle, barrier-repairing ingredients and soothing agents like ceramides and centella asiatica.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34694692/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this booster clog pores, cause breakouts or purging for sensitive skin?

This booster is unlikely to clog pores or cause breakouts for sensitive skin because it contains no harsh ingredients and includes soothing components. Sensitive skin needs gentle, calming ingredients like glycerin and soothing plant extracts to keep pores clear while maintaining hydration without heavy oils.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Is this booster fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for sensitive skin

- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/sensitive-skin) — Superior fit — $53.00 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/sensitive-skin) — High fit — $39.99 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/sensitive-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/sensitive-skin) — Superior fit — $28.08 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [innisfree Daily Mild Sunscreen](https://lovi.care/skincare/p/innisfree/daily-mild-sunscreen/for/sensitive-skin) — Superior fit — $18.00 at Amazon

## Where to buy

- Amazon.com: $59.00 (https://www.amazon.com/dp/B0BV3F1X4H?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Glycerin, Peg-8 Dimethicone, Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Hexapeptide-12, Myristoyl Hexapeptide-16, Myristoyl Pentapeptide-17, Hexanoyl Dipeptide-3 Norleucine Acetate, Azelaoyl Bis-Dipeptide-10, Glycoproteins, Adenosine, Dipotassium Glycyrrhizate, Arginine, Valine, Glycine, Alanine, Glutamic Acid, Serine, Threonine, Yeast Extract, Isoleucine, Proline, Histidine, Phenylalanine, Pca, Phytic Acid, Panax Ginseng Root Extract, Sodium Pca, Psidium Guajava Fruit Extract, Euterpe Oleracea Fruit Extract, Ahnfeltiopsis Concinna Extract, Dextran, Hydrolyzed Silk, Lecithin, Glyceryl Polymethacrylate, C12-16 Pareth-9, Trideceth-12, Sodium Lactate, Carbomer, Aspartic Acid, Polysorbate 20, Butylene Glycol, Caprylyl Glycol, C11-15 Pareth-7, Guar Hydroxypropyltrimonium Chloride, Phytosteryl Octyldodecyl Lauroyl Glutamate, Ectoin, Citrate Buffer, Trimethylsiloxyamodimethicone, Phenoxyethanol, Sodium Hydroxide, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/peptide-booster/for/sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/peptide-booster/for/sensitive-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/peptide-booster/for/sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/peptide-booster/for/sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/peptide-booster/for/sensitive-skin