# Paula's Choice 10% Niacinamide Booster for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Paula's Choice](https://lovi.care/skincare/brands/paula-s-choice)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few serums fit it even better.

## Why this fit

- Offers high suitability for your dry skin as niacinamide and sodium hyaluronate provide essential hydration and improve your skin barrier function. Acetyl glucosamine further aids in evening your skin tone and minimizing pores.
- Allantoin and panthenol contribute to barrier repair, enhancing overall skin comfort and health.
- The formula is safe for your dry skin, containing no harsh or irritating ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/dry-sensitive-skin): Superior
- [Oily acne-prone skin](https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Acetyl Glucosamine, Sodium Hyaluronate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Panthenol Vitamin B5

## What the research says

- Topical 2% N-acetyl glucosamine reduced facial hyperpigmentation in an 8-week split-face clinical test, with an even greater effect observed when combined with 4% niacinamide. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/))
- Niacinamide significantly decreased hyperpigmentation and increased skin lightness compared with vehicle alone after 4 weeks of use in women by inhibiting melanosome transfer. ([The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- N-acetyl-glucosamine-loaded nanostructured lipid carriers successfully delivered the hydrophilic agent through the skin and reduced melanin distribution in healthy volunteers. ([Advanced Pharmaceutical Bulletin, 2016](https://pubmed.ncbi.nlm.nih.gov/28101465/))
- Topical cosmetic products containing hyaluronic acid, N-acetyl glucosamine, and gamma-amino butyric acid improved skin hydration by 24.28% to 33.60%, elasticity by 11.98%, and skin lightening by 5.26% over 2 months in 20 female participants. ([Journal of Cosmetic and Laser Therapy, 2019](https://pubmed.ncbi.nlm.nih.gov/30040516/))
- Liposomes containing N-acetyl glucosamine prepared using the fusion method significantly increased skin moisture content compared to empty liposomes in human volunteers over a 5-hour period. ([Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23725302/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Combining 755 nm alexandrite laser with topical licorice gel significantly reduces terminal hair counts compared to alexandrite laser with placebo in women with idiopathic hirsutism. ([Evidence-based Complementary and Alternative Medicine, 2015](https://pubmed.ncbi.nlm.nih.gov/26273313/))
- Licochalcone A activated Nrf2 signaling, elevated cytoprotective enzymes, increased the reduced-to-oxidized glutathione ratio, and decreased reactive oxygen species in human fibroblasts and neutrophils, while a LicA-rich licorice extract lowered UVA-induced oxidative processes in vivo. ([Experimental Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25381913/))
- Bioactive glycyrrhizic acid and oxymatrine ionic liquid self-assembled nanomicelles significantly promoted the transdermal permeation, subcutaneous retention, and anti-photoaging efficacy of palmitoyl pentapeptide-4 in cellular and animal models compared to unformulated peptide. ([Advanced Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39783908/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Users with oily and combination skin frequently praise this booster for its ability to visibly minimize pores and smooth rough texture, often describing the results as transformative for congestion and post-acne marks. A significant minority of reviewers experience adverse reactions, including breakouts and redness, while others find the price point high for the small quantity provided.

- Liked: Minimizes enlarged pores (mostly mentioned)
- Liked: Improves skin texture (often mentioned)
- Liked: Lightweight & layerable (often mentioned)
- Liked: Controls oil production (sometimes noted)
- Liked: Fades marks & redness (sometimes noted)
- Disliked: Causes breakouts/irritation (sometimes noted)
- Disliked: Expensive for size (sometimes noted)
- Disliked: No visible results (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Sticky/tacky finish (rarely noted)

## How to apply

- Apply this serum PM, starting 3×/week and working up to daily use as your skin adjusts.
- Place the serum after cleansing and toner, but right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on slightly damp skin to help lock in extra moisture.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Paula's Choice 10% Niacinamide Booster a great fit for dry skin?

Paula's Choice 10% Niacinamide Booster is a great fit for dry skin because niacinamide and sodium hyaluronate provide essential hydration and improve your skin barrier function. Acetyl glucosamine further aids in evening your skin tone and minimizing pores, while allantoin and panthenol contribute to barrier repair and overall skin comfort. The formula is safe for your dry skin, containing no harsh or irritating ingredients.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Which ingredients make this serum a good fit for dry skin?

This serum is a great fit for your dry skin because niacinamide and sodium hyaluronate provide essential hydration and improve your skin barrier function. Acetyl glucosamine, allantoin, and panthenol further help by evening your skin tone, minimizing pores, and enhancing overall skin comfort.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### What does Niacinamide do for dry skin?

Niacinamide helps dry skin by strengthening the skin barrier, increasing hydration, and reducing water loss. It supports ceramide production and helps keep the surface smooth and calm. This ingredient tends to be very well tolerated and is unlikely to irritate dry skin.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/42108609/)

### What does Acetyl Glucosamine do for dry skin?

Acetyl glucosamine helps dry skin by increasing moisture and making the skin feel soft and smooth. It may also decrease flakiness and help normalize how the skin sheds dry surface flakes.
Sources: [Journal of Cosmetic Science, 2009](https://pubmed.ncbi.nlm.nih.gov/19691938/)

### Where does this serum go in a skincare routine for dry skin?

This treatment goes in your evening routine after cleansing and before your moisturizer. It is safe for your dry skin and helps provide essential hydration, improve your skin barrier, and keep your skin comfortable.

### Can I use it with retinol, and in what order?

Yes, you can use this treatment with retinol by applying the retinol first and following it with this booster. This routine helps deliver essential hydration and supports your skin barrier while keeping your dry skin comfortable.

### How often should I use this serum?

This serum is a great fit for your dry skin, and you can safely use it in the evening as part of your routine. Niacinamide and sodium hyaluronate provide essential hydration while improving your skin barrier function.
Sources: [Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17348991/)

### Can it clog pores, cause breakouts or purging for dry skin?

Paula's Choice 10% Niacinamide Booster is unlikely to clog pores, though some reviewers do report breakouts and irritation. The formula contains gentle, hydrating ingredients that are very safe for dry skin.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-skin) — Superior fit — $16.75 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-skin) — Superior fit — $53.00 at Amazon
- [ma:nyo Bifida Biome Complex Ampoule](https://lovi.care/skincare/p/ma-nyo/bifida-biome-complex-ampoule/for/dry-skin) — Superior fit — $19.90 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — $19.99 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — $16.99 at Amazon
- Moisturizer: [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/dry-skin) — Superior fit — $22.00 at Amazon

## Where to buy

- Amazon.com: $53.00 (https://www.amazon.com/dp/B01GF1EOB8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Niacinamide, Acetyl Glucosamine, Ascorbyl Glucoside Ascorbic Acid, Butylene Glycol, Sodium Hyaluronate, Allantoin, Boerhavia Diffusa Root Extract, Glycerin, Dipotassium Glycyrrhizate, Glycyrrhiza Glabra Root Extract Licorice Root Extract, Ubiquinone, Epigallocatechin Gallate, Beta-Glucan, Panthenol, Carnosine, Genistein, Citric Acid, Sodium Citrate, Sodium Hydroxide, Xanthan Gum, Disodium Edta, Ethylhexylglycerin, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/paula-s-choice/10-niacinamide-booster/for/dry-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- France: https://lovi.care/skincare/fr/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/paula-s-choice/10-niacinamide-booster/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/paula-s-choice/10-niacinamide-booster/for/dry-skin