# Olay Regenerist Retinol 24 Night Moisturizer for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Olay](https://lovi.care/skincare/brands/olay)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Offers excellent moisturizing and anti-aging effects for your oily skin due to the presence of retinol and niacinamide, which hydrate and smooth texture while niacinamide helps regulate sebum.
- Dimethicone and glycerin provide general hydration, and sodium hyaluronate offers humectant action, though more mattifying ingredients could further enhance suitability for oiliness.
- The formula is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/mature-skin): Superior
- [Dry sensitive skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Retinol, Sodium Hyaluronate, Niacinamide, Glycerin, Peptides

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, users consistently praise this moisturizer for its ability to make skin feel noticeably smoother, softer, and brighter overnight without the irritation often associated with retinol. Many appreciate the fragrance-free, non-greasy formula that absorbs quickly, though a subset of users experienced breakouts or found the jar packaging unhygienic.

- Liked: Smoother, softer skin (mostly mentioned)
- Liked: Gentle & fragrance-free (often mentioned)
- Liked: Lightweight & non-greasy (often mentioned)
- Liked: Visible brightening (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Lack of results (rarely noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Olay Regenerist Retinol 24 Night Moisturizer a great fit for oily acne-prone skin?

This moisturizer is a great fit because retinol and niacinamide hydrate your skin and smooth its texture, while niacinamide helps regulate oil. Ingredients like dimethicone, glycerin, and sodium hyaluronate also provide hydration without harsh irritants.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

This cream is a great fit for oily acne-prone skin because retinol and niacinamide hydrate and smooth your skin while helping regulate oil. Ingredients like glycerin, dimethicone, and sodium hyaluronate provide lightweight hydration without clogging pores.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does Retinol do for oily acne-prone skin?

Retinol helps oily acne-prone skin by clearing up breakouts and smoothing the skin, though it may occasionally cause some mild scaling or stinging. This ingredient works by addressing the root causes of acne, making it a reliable choice for keeping pores clear and skin smooth.
Sources: [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/), [Journal of Drugs in Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30586483/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by reducing sebum production and lipid synthesis in sebaceous glands. It also supports skin barrier function and improves hydration while helping deliver treatments without causing irritation.
Sources: [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/), [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes in the evening routine after cleansing and before your final moisturizer, as part of a simple and safe nighttime approach to active skincare. Retinol and niacinamide help hydrate and smooth your skin while regulating oil, and the formula is unlikely to cause irritation.
Sources: [International Journal of Cosmetic Science, 2020](https://pubmed.ncbi.nlm.nih.gov/31461548/)

### Can I use this cream with vitamin C, and in what order?

You can use this cream in the evening and vitamin C in the morning. This routine separates the two active ingredients to keep your skin calm while helping smooth texture and brighten.

### How often should I use this cream?

Use this treatment in the evening as part of your nighttime routine. Applying it daily helps hydrate and smooth your skin while keeping it safe from irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is a great fit for your oily acne-prone skin and is unlikely to cause irritation or breakouts. Reviewers rarely mention breakouts, and the formula contains ingredients like niacinamide that help smooth texture and regulate oil.

### Can I use this cream around the eyes or on my body?

Yes, you can use this cream around your eyes and on your body, as its formula is safe and well-tolerated by the skin. The skin around your eyes and in certain body areas is quite thin, so hydrating and smoothing ingredients like retinol, niacinamide, and sodium hyaluronate help care for these delicate zones without harshness.

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol, stearyl alcohol, and cetearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — $15.88 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — $15.50 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — $22.25 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — $25.99 at Amazon

## Where to buy

- Amazon.com: $35.99 (https://www.amazon.com/dp/B08CD979ZS?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Dimethicone, Glycerin, Niacinamide, Retinol, Aminopropyl Ascorbyl Phosphate, Palmitoyl Pentapeptide-4, Sodium Hyaluronate, Tocopheryl Acetate, Panthenol, Cetyl Alcohol, Stearyl Alcohol, Cetearyl Glucoside, Cetearyl Alcohol, Polyacrylamide, C13-14 Isoparaffin, Laureth-7, Dimethiconol, Caprylyl Glycol, Phenoxyethanol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin
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- Netherlands: https://lovi.care/skincare/nl/p/olay/regenerist-retinol-24-night-moisturizer/for/oily-acne-prone-skin
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