# Olay Regenerist Collagen Peptide 24 Serum for acne-prone skin

**Lovi Fit: Average fit for acne-prone skin.**
Combination Skin Fit: Superior · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Olay Regenerist](https://lovi.care/skincare/brands/olay-regenerist)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with acne-prone skin: breakouts, blackheads, and post-acne marks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for acne-prone skin; other serums fit it better.

## Why this fit

- Offers moderate hydration and soothing for your acne-prone skin, as Glycerin and Panthenol provide essential moisture and calming effects. Niacinamide and Palmitoyl Pentapeptide-4 also contribute to seboregulation and collagen stimulation, making it suitable for combination skin.
- The serum provides excellent plumping and firming benefits due to Palmitoyl Pentapeptide-4 and Tremella Fuciformis Sporocarp Extract, addressing general skincare needs.
- The safety profile is excellent, with no risks of irritation for your acne-prone skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/acne-prone-skin): Average (this page)
- [Skin with dark spots](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/olay-regenerist/collagen-peptide-24-serum/for/oily-acne-prone-skin): High

## Key ingredients

Collagen Peptides, Niacinamide, Glycerin, Panthenol Vitamin B5, Tremella Fuciformis Sporocarp Extract

## What the research says

- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical palmitoyl pentapeptide (pal-KTTKS) provided significant improvement versus placebo control in the reduction of wrinkles and fine lines in Caucasian female subjects. ([International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/))
- Tremella fuciformis polysaccharides effectively alleviate UVA-induced photodamage in human dermal fibroblasts by reducing ROS and MDA, increasing antioxidant enzyme activities, up-regulating Nrf2 while down-regulating Keap1 expression, and increasing collagen I, elastin, and hyaluronic acid content. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33686752/))
- A functionalized dendrimer nanocarrier delivers active ingredients into the dermis and enhances collagen production in human dermal fibroblasts by co-delivering all-trans retinol and palmitoyl pentapeptide-4. ([Acta Biomaterialia, 2025](https://pubmed.ncbi.nlm.nih.gov/39694719/))
- A liquid formulation containing hydrolyzed collagen demonstrated structural stability, peptide mass distribution between 0.5 and 19.5 kDa, and faded forehead wrinkles in five volunteers while proving to be non-irritating and hypoallergenic. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32390321/))
- Exposure to collagen peptides increased the expression of COL1A1, ELN, and VCAN genes and collagen protein levels in cultured human dermal fibroblasts compared to untreated controls. ([Frontiers in Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38751975/))
- Salmo salar and Tilapia nilotica skin collagen peptides accelerate wound healing in a rat murine wound model by reducing proinflammatory cytokines, upregulating BD14, NOD2, IL-10, VEGF, and beta-FGF, and favorably altering wound microflora colonization compared to untreated controls. ([Journal of Agricultural and Food Chemistry, 2020](https://pubmed.ncbi.nlm.nih.gov/31967468/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))
- Snow mushroom alcohol-based hand rub gel significantly improved skin moisture better than the placebo through 180 minutes while maintaining comparable antiseptic efficacy in 20 human volunteers. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/32531816/))
- Tremella fuciformis extract demonstrates potential cutaneous benefits including skin antiaging, photoprotection, wound healing, and barrier protection based on in vitro and animal models. ([Archives of Dermatological Research, 2023](https://pubmed.ncbi.nlm.nih.gov/36757441/))
- Tremella fuciformis inhibits melanogenesis by decreasing melanin content and tyrosinase expression in B16F10 cells while promoting wound healing in human HaCaT keratinocytes and Detroit 551 fibroblasts. ([In Vivo, 2022](https://pubmed.ncbi.nlm.nih.gov/35241526/))

## What reviewers say

Based on a very large amount of data, this serum is widely praised for its lightweight, non-greasy texture and its ability to provide deep, lasting hydration. Users frequently report that it effectively plumps the skin, smooths fine lines, and improves overall radiance, making it a popular choice for those targeting signs of aging, dullness, and dehydration.

- Liked: Deeply hydrating (mostly mentioned)
- Liked: Fast absorbing (mostly mentioned)
- Liked: Lightweight feel (often mentioned)
- Liked: Plumps skin (often mentioned)
- Liked: Smooths texture (often mentioned)
- Disliked: Fiddly dropper (sometimes noted)
- Disliked: Limited tightening (rarely noted)
- Disliked: Price point (rarely noted)

## How to apply

- Use your serum as part of your PM routine and start 3x/week before working up to daily use.
- Apply this treatment after cleansing and toner, and before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and let it absorb for a minute.
- Apply the product on clean, dry skin to help manage your breakouts safely.
- Avoid the eye area and do a patch test before your first use.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Olay Collagen Peptide 24 Serum work for acne-prone skin?

This serum works moderately well for acne-prone skin, offering basic moisture and calming effects without causing irritation. However, acne-prone skin needs a treatment that specifically targets breakouts with ingredients like niacinamide, zinc PCA, or propolis to balance oil and maintain clarity.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Which ingredients make this serum a good fit for acne-prone skin?

Glycerin and Panthenol help make this serum a good fit for your acne-prone skin by offering moderate moisture and calming effects, while Niacinamide assists with oil balance. To fit this skin even better, an acne-prone treatment needs ingredients like niacinamide, propolis, or zinc PCA that target breakouts and control oil without causing excess dryness.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### What do Collagen Peptides do for acne-prone skin?

Collagen peptides are unlikely to directly treat acne, but they help improve overall skin hydration and elasticity. To properly care for acne-prone skin, this product needs ingredients that gently clear pores and calm irritation.
Sources: [Nutrients, 2026](https://pubmed.ncbi.nlm.nih.gov/42451143/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### What does Niacinamide do for acne-prone skin?

Niacinamide helps acne-prone skin by reducing both inflamed and uninflamed breakouts and calming redness. It is also very helpful for keeping oily skin balanced by cutting down on excess oil production, and it is well tolerated by most people.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/), [Cureus, 2024](https://pubmed.ncbi.nlm.nih.gov/38725769/)

### Where does this serum go in a skincare routine for acne-prone skin?

This serum goes in the evening routine after cleansing and before moisturizing, making it simple and safe for your skin. Acne-prone skin needs a product of this type that offers lightweight moisture, soothing components, and ingredients that help balance oil.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying it before your retinol at night to help keep your skin calm and moisturized. Because this product offers an average fit for your acne-prone skin, an ideal product of this type needs targeted blemish-clearing ingredients and lightweight hydrators to properly care for breakouts.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/), [International Journal of Cosmetic Science, 2005](https://pubmed.ncbi.nlm.nih.gov/18492182/)

### How often should I use this serum?

You can use this treatment in the evening as part of your routine for simplicity and extra safety around sun exposure. This serum is unlikely to irritate your acne-prone skin, though this skin type needs products with extra oil control and soothing ingredients.

### Can this serum clog pores, cause breakouts or purging for acne-prone skin?

This serum is unlikely to clog pores or cause breakouts for your acne-prone skin, as it has a very safe formula without harsh ingredients and includes soothing components. To work best for acne-prone skin, a product of this type needs lightweight hydrators and calming ingredients that provide essential moisture without heavy oils.
Sources: [American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/acne-prone-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/acne-prone-skin) — Superior fit — $28.88 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/acne-prone-skin) — Superior fit — $39.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/acne-prone-skin) — Superior fit — $15.60 at Amazon
- Moisturizer: [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/acne-prone-skin) — Superior fit — $15.50 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Dimethicone, Niacinamide, Glycerin, Panthenol, Palmitoyl Pentapeptide-4, Tremella Fuciformis Sporocarp Extract, Hydroxyacetophenone, C13-14 Isoparaffin, Laureth-4, Polysorbate 20, Laureth-7, Disodium Edta, Polyacrylamide, Dimethicone Crosspolymer, Phenoxyethanol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

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