# Obagi Kinetin+ Hydrating Cream for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: Excellent.

Page: https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Obagi](https://lovi.care/skincare/brands/obagi)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your normal skin, this product effectively addresses wrinkles and fine lines with kinetin and zeatin, which promote cellular regeneration and collagen production to smooth texture.
- The inclusion of aloe barbadensis leaf juice and panthenol further enhances barrier resilience and hydration, supporting overall skin health.
- The safety profile is excellent, with no risks of irritation due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/oily-acne-prone-skin): Average

## Key ingredients

Kinetin, Zeatin, Aloe Barbadensis Leaf Juice, Ascorbic Acid, Hydrolyzed Elastin

## What the research says

- Kinetin treatment increased involucrin and keratin 1 mRNA expression in HaCaT cells and improved skin moisture and transepidermal water loss while decreasing skin texture roughness in subjects using kinetin-containing cream compared to baseline. ([Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/))
- A new topical panthenol-containing emollient significantly improved transepidermal water loss reduction, stratum corneum hydration, and intercellular lipid lamellae length compared with control in healthy subjects without negatively impacting bacterial viability. ([The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- A panthenol-enriched mask significantly decreased erythema and hyperpigmentation, increased sebum and stratum corneum moisture, and reduced transepidermal water loss compared to a saline dressing in 60 subjects undergoing facial laser treatment. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40613435/))
- Topical combination of kinetin and niacinamide exerts synergistic anti-aging effects with significant reductions in spot, pore, wrinkle, and evenness counts, alongside increased hydration and decreased erythema in Taiwanese subjects compared to placebo. ([Journal of Cosmetic Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/18047609/))
- Cosmetic formulations containing a liposomal dispersion of magnesium ascorbyl phosphate, alpha-lipoic acid, and kinetin provided photoprotection against UV damage in hairless mouse skin and enhanced stratum corneum and deeper layer skin moisture in human volunteers after four weeks of daily applications. ([Photochemistry and Photobiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22236139/))
- Topical 0.1% kinetin cream applied twice daily for 12 weeks resulted in slight but statistically significant improvements in overall skin condition, texture, color, and wrinkles among 100 Thai subjects with facial photo-damage compared to baseline. ([Indian Journal of Dermatology, Venereology and Leprology, 2015](https://pubmed.ncbi.nlm.nih.gov/25994881/))
- Pretreatment with trans-Zeatin significantly inhibits UVB-induced MMP-1 expression, c-Jun activation, and MAPK phosphorylation in cultured human skin fibroblasts compared to UVB irradiation alone. ([International Journal of Molecular Medicine, 2009](https://pubmed.ncbi.nlm.nih.gov/19288033/))
- Long-term treatment with zeatin in human skin fibroblasts undergoing aging in vitro prevented cell enlargement, reduced intracellular debris, prevented actin polymerization, and enhanced stress tolerance without increasing maximum proliferative capacity. ([Rejuvenation Research, 2005](https://pubmed.ncbi.nlm.nih.gov/15798374/))
- Trans-Zeatin treatment attenuates ultraviolet-induced aquaporin-3 loss, delayed wound healing, and decreased water permeability in cultured human skin keratinocytes through the inhibition of MEK/ERK activation. ([International Journal of Molecular Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20596606/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of a 0.1% copper-zinc malonate-containing cream significantly enhanced elastin biosynthesis and induced elastic fibre regeneration in photoaged facial skin of 21 female patients after 6 weeks of treatment compared to baseline. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/19400831/))
- A betaine-based deep eutectic solvent successfully enhanced the transdermal delivery of elastin peptide, which improved skin barrier repair, reduced melanin secretion and deposition, and stimulated the secretion of procollagen I and elastin. ([Biomaterials Advances, 2024](https://pubmed.ncbi.nlm.nih.gov/39053386/))
- Bioactive recombinant humanized elastin (RHE) gel effectively restores skin elasticity, reverses UV-induced damage and oxidative stress, and promotes extracellular matrix remodeling in zebrafish and aged mice models compared to commercial vitamin E and recombinant humanized collagen gels. ([Materials Today. Bio, 2025](https://pubmed.ncbi.nlm.nih.gov/40978161/))

## What reviewers say

While many report visible improvements in skin texture and fine lines, some users find the price point too high and have experienced significant frustration with the airless pump packaging.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight texture (often mentioned)
- Liked: Soothing & calming (often mentioned)
- Liked: Anti-aging benefits (sometimes noted)
- Disliked: Faulty packaging (sometimes noted)
- Disliked: High price (sometimes noted)
- Disliked: Acne/Breakouts (rarely noted)
- Disliked: Texture dislike (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Obagi Kinetin+ Hydrating Cream a great fit for mature skin?

This cream is a great fit because kinetin and zeatin help smooth fine lines by encouraging skin renewal and collagen production. Aloe vera and panthenol further support overall skin health by boosting hydration and strengthening the skin barrier, with an excellent safety profile that is unlikely to cause irritation.
Sources: [Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because it contains kinetin and zeatin, which help smooth texture by encouraging skin renewal. Ingredients like aloe barbadensis leaf juice and panthenol also boost moisture and strengthen the skin barrier.
Sources: [Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### What does Kinetin do for mature skin?

Kinetin helps improve the look of mature skin by smoothing out rough texture, reducing wrinkles, and keeping the skin hydrated. It is unlikely to cause adverse effects, making it a gentle option for aging skin.
Sources: [Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/), [Rejuvenation Research, 2004](https://pubmed.ncbi.nlm.nih.gov/15256043/)

### What does Zeatin do for mature skin?

Zeatin helps smooth mature skin and keeps it looking fresh by supporting cell health and stress tolerance as it ages. It is unlikely to cause irritation and may help prevent the physical changes that happen to skin over time.
Sources: [Rejuvenation Research, 2005](https://pubmed.ncbi.nlm.nih.gov/15798374/)

### Where does this cream go in a skincare routine for mature skin?

This hydrating cream goes in the morning routine after a hydrating toner and before SPF, and in the evening routine after your treatment step. It is a great fit for mature skin, helping to smooth fine lines and support hydration without irritation.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying your retinol first, letting it absorb, and then following with this moisturizer. Using a barrier-supporting moisturizer helps reduce irritation and makes the adjustment to retinol easier on your skin.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily for your mature skin. Regular application helps smooth fine lines, softens texture, and keeps your skin well-hydrated.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This cream is unlikely to clog pores or cause breakouts for mature skin, as reviewers rarely report acne and the formula lacks heavy, harsh ingredients. It helps keep skin smooth and hydrated while supporting your natural skin barrier.
Sources: [The Journal of Dermatological Treatment, 2017](https://pubmed.ncbi.nlm.nih.gov/27425824/), [Annals of Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28223740/)

### Can I use this cream around the eyes or on my body?

You can use this cream around your eyes and on your body to help smooth fine lines and keep the skin soft. The gentle formula has an excellent safety profile, making it unlikely to cause irritation on thinner areas of skin.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [European Journal of Pharmaceutics and Biopharmaceutics, 2014](https://pubmed.ncbi.nlm.nih.gov/24056055/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetyl alcohol and stearyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for mature skin

- [Medi-Peel Peptide 9 Volume Tox Cream](https://lovi.care/skincare/p/medi-peel/peptide-9-volume-tox-cream/for/mature-skin) — Superior fit — $21.55 at Amazon
- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/mature-skin) — Superior fit — $125.00 at Amazon
- [StriVectin SD Advanced Plus Intensive Moisturizing Concentrate](https://lovi.care/skincare/p/strivectin/sd-advanced-plus-intensive-moisturizing-concentrate/for/mature-skin) — High fit — $149.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

- Amazon.com: $39.99 (https://www.amazon.com/dp/B0F47MTCX8?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 31 Oct 2026.

## Ingredients

Water, Glyceryl Stearate, Propylene Glycol, Octyldodecyl Myristate, Stearic Acid, Cetyl Alcohol, Peg-12 Glyceryl Dimyristate, Stearyl Alcohol, Lactobacillus Ferment, Glycine Soja Soybean Sterols, Phenoxyethanol, Laureth-23, Dimethicone, Carbomer, Tocopheryl Acetate, Ethoxydiglycol, Sodium Hydroxide, Ethylhexylglycerin, Kinetin, Zeatin, Pentaerythrityl Tetra-Di-T-Butyl Hydroxyhydrocinnamate, Disodium Edta, Panthenol, Citric Acid, Ascorbic Acid, Hydrolyzed Elastin, Water-Soluble Collagen, Aloe Barbadensis Leaf Juice, Hydrochloric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/obagi/kinetin-hydrating-cream/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/obagi/kinetin-hydrating-cream/for/mature-skin
- France: https://lovi.care/skincare/fr/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/obagi/kinetin-hydrating-cream/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/obagi/kinetin-hydrating-cream/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/obagi/kinetin-hydrating-cream/for/mature-skin