# NUE Barrier Clear Treatment for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [NUE](https://lovi.care/skincare/brands/nue)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate treatment for your oily, acne-prone skin as Dendriclear and Live Probiotic help reduce acne lesions and blemishes while providing seboregulation and anti-inflammatory action.
- Mangifera Indica Leaf Extract offers general soothing benefits that are supportive for your oily shine.
- The product is safe for your oily skin with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/oily-acne-prone-skin): Average

## Key ingredients

Live Probiotic, Dendriclear

## What the research says

- Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers. ([International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/))
- Topical application of live Lactobacillus reuteri DSM 17938 and its lysate reduced proinflammatory IL-6 and IL-8 in UVB-R-induced inflammation models, with live bacteria also increasing aquaporin 3 expression and exhibiting antimicrobial activity against skin pathogens. ([Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31021014/))
- Topical probiotics, synbiotics, and postbiotics promote antimicrobial and anti-inflammatory properties, angiogenesis, tissue regeneration, and skin barrier restoration in preclinical wound models compared to untreated or control conditions. ([Pharmaceuticals, 2025](https://pubmed.ncbi.nlm.nih.gov/40430523/))
- Mangifera indica extract reduced lipid production by 40% in sebocytes, improved sebum quality and quantity in Caucasian volunteers, reduced porphyrins expression, and decreased C. acnes lipase activity by 29% compared to placebo while protecting microbiota equilibrium. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/))

## What reviewers say

It is frequently highlighted as a gentle, effective solution for those with sensitive or breakout-prone skin who need barrier support alongside blemish control.

- Liked: Calms breakouts (often mentioned)
- Liked: Gentle on skin (often mentioned)
- Liked: Non-greasy formula (sometimes noted)
- Liked: Strengthens barrier (sometimes noted)
- Disliked: Ineffective for some (rarely noted)
- Disliked: Price point (rarely noted)
- Disliked: Slow results (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does NUE Barrier Clear Treatment work for oily skin?

NUE Barrier Clear Treatment works moderately well for your oily skin, helping calm blemishes and oily shine without any risk of irritation. A treatment for oily skin needs ingredients like niacinamide to control excess oil and pores, along with soothing extracts and light hydrators to keep the skin comfortable every day.
Sources: [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/), [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/)

### Which ingredients make this treatment a good fit for oily skin?

Dendriclear and Live Probiotic help make this a good fit by reducing acne and blemishes while managing oily shine and inflammation. Mangifera Indica Leaf Extract also provides soothing benefits, and this treatment needs ingredients like niacinamide, zinc PCA, and lightweight hydrators to better control excess oil and pores without clogging skin.
Sources: [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/), [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/)

### What does Live Probiotic do for oily skin?

Live Probiotic helps oily skin by reducing the bacteria that cause breakouts and calming redness. It is unlikely to feel heavy, and this type of product for oily skin needs ingredients that balance oil and strengthen the skin barrier without clogging pores.
Sources: [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/), [ACS Applied Bio Materials, 2025](https://pubmed.ncbi.nlm.nih.gov/39814597/)

### What does Dendriclear do for oily skin?

Dendriclear helps oily and acne-prone skin by rebalancing your skin's bacteria, specifically reducing acne-causing strains while keeping helpful bacteria safe. It also helps calm redness and swelling so your skin feels clearer and more comfortable.
Sources: [Pharmaceutics, 2023](https://pubmed.ncbi.nlm.nih.gov/37631297/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and before moisturizing, which keeps things simple and safe around sun exposure. A product of this type for oily skin needs ingredients like Live Probiotic and Dendriclear to help reduce blemishes and control oil, alongside soothing plant extracts.

### Can I use this treatment with retinol, and in what order?

You can use this treatment alongside retinol, but to keep your oily skin calm it is best to apply retinol first and follow with this treatment once it has absorbed. Using ingredients that balance oil and soothe the skin helps manage breakouts while reducing the irritation that strong routines may cause.
Sources: [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/), [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/)

### How often should I use it?

You can use this treatment in the evening as part of your nighttime routine. It is safe for oily skin, but because other products may fit your skin better, this skin also needs ingredients and benefits that balance oil and soothe blemishes.
Sources: [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/), [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/)

### Can this treatment clog pores, cause breakouts or purging for oily skin?

This treatment is unlikely to clog pores or cause breakouts on oily skin, as it is free of harsh ingredients and helps calm acne and reduce blemishes. However, because other products may fit oily skin better, an ideal choice for this skin type should include ingredients that balance oil production and soothe inflammation without feeling heavy.
Sources: [Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35897945/), [International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/)

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — $28.88 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — $39.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Live Probiotic, Dendriclear, Acb Bio-Chelate 5pf, Mangifera Indica Leaf Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/nue/barrier-clear-treatment/for/oily-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/nue/barrier-clear-treatment/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/nue/barrier-clear-treatment/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/nue/barrier-clear-treatment/for/oily-skin
- France: https://lovi.care/skincare/fr/p/nue/barrier-clear-treatment/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/nue/barrier-clear-treatment/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/nue/barrier-clear-treatment/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/nue/barrier-clear-treatment/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/nue/barrier-clear-treatment/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/nue/barrier-clear-treatment/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/nue/barrier-clear-treatment/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/nue/barrier-clear-treatment/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/nue/barrier-clear-treatment/for/oily-skin