# Nu Skin ageLOC Tru Face Essence Ultra for combination skin

**Lovi Fit: Average fit for combination skin.**
Combination Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Nu Skin](https://lovi.care/skincare/brands/nu-skin)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for combination skin; other serums fit it better.

## Why this fit

- Offers moderate skin firming for your combination skin due to Pistacia Lentiscus Gum and Centella Asiatica Extract, which improve elasticity and reduce fine lines, though these do not directly address your oily shine concerns.
- Squalane and Tocopherol provide general hydration and antioxidant support, which are beneficial but not specifically targeted for managing excess oil.
- The product is safe for your combination skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin): Average (this page)
- [Sensitive skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/oily-acne-prone-skin): Average

## Key ingredients

Squalane, Retinyl Palmitate, Tetrahexyldecyl Ascorbate, Centella Asiatica Extract, Dunaliella Salina Extract

## What the research says

- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Application of squalene/phosphotungstate calcium nanowires (Sql/PWC) oleogel on UVB-irradiated skin decreased epidermal thickness, increased dermal thickness, and promoted the expression of elastin, collagen, and skin barrier markers through antioxidant and anti-inflammatory activities. ([Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/))
- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- Retinyl palmitate ethosomal hydrogel reduced non-inflammatory and total acne lesion counts significantly better than marketed tretinoin while improving tolerability with minimal skin irritation in patients with acne vulgaris. ([International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- A Dunaliella salina extract significantly reduced skin glycation scores, histamine sensitivity, wrinkle counts, and spots compared to placebo under intense solar exposure. ([Marine Drugs, 2022](https://pubmed.ncbi.nlm.nih.gov/35200634/))
- Phytoene- and phytofluene-rich tomato and Dunaliella salina extracts show no significant cytotoxic, genotoxic, irritant, or sensitizing potential, supporting their safe human topical use. ([Journal of Toxicology, 2018](https://pubmed.ncbi.nlm.nih.gov/29849613/))

## Why other serums fit combination skin better

- Niacinamide and ferulic acid incorporated in a stable multiple emulsion successfully reduced melanin, sebum, and skin erythema while improving skin elasticity and hydration in human skin compared to a placebo. ([BioMed Research International, 2022](https://pubmed.ncbi.nlm.nih.gov/35342760/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does Nu Skin Tru Face Essence Ultra work for combination skin?

This product works moderately well for combination skin because it helps firm the skin and provides general hydration with ingredients like squalane and centella asiatica extract, though it does not manage excess oil. A treatment of this type needs ingredients like niacinamide, zinc PCA, and propolis to balance oily areas and enhance radiance without causing irritation.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### Which ingredients make this serum a good fit for combination skin?

Squalane and Centella Asiatica Extract help make this serum a fit by offering gentle hydration and firming support for your skin. To truly suit combination skin, a product of this type needs ingredients like niacinamide and zinc PCA that manage oily shine while keeping the face balanced.
Sources: [Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### What does Squalane do for combination skin?

Squalane helps keep combination skin soft and smooth by locking in moisture without feeling heavy or greasy. It supports the skin barrier and provides lightweight hydration that works well for both dry and oily areas.
Sources: [Skin Health and Disease, 2024](https://pubmed.ncbi.nlm.nih.gov/39355739/), [Journal of Nanobiotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40001122/)

### What does Retinyl Palmitate do for combination skin?

Retinyl palmitate helps smooth fine lines, even out skin tone, and improve texture on combination skin. Because it works gently, it is unlikely to cause irritation while helping keep both dry and oily areas looking clear and firm.
Sources: [Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/), [Colloids and Surfaces. B, Biointerfaces, 2011](https://pubmed.ncbi.nlm.nih.gov/21411295/)

### Where does this serum go in a skincare routine for combination skin?

Apply this treatment in the evening routine, after cleansing and toning and before moisturizing, for simplicity and extra safety around sun exposure. Combination skin works best with treatments that also help manage excess oil.

### Can I use this serum with retinol, and in what order?

This treatment already contains Retinyl Palmitate, so adding another retinol product may increase the likelihood of skin irritation. If you choose to use both, apply the gentlest product first and listen to your skin to see how it feels.

### How often should I use this serum?

You can use this treatment in the evening as part of your routine. Combination skin also needs lightweight, oil-controlling ingredients like niacinamide or salicylic acid to help manage shine.

### Can this serum clog pores, cause breakouts or purging for combination skin?

This treatment is unlikely to cause irritation on your combination skin, but it is not specifically targeted for managing excess oil. A product of this type needs ingredients that help balance oil and clear pores while providing hydration.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Cyclopentasiloxane, Squalane, Dimethiconol, Caprylic Capric Triglyceride, Olea Europaea Oil Fruit Olive Oil Fruit, Carthamus Tinctorius Seed Oil, Dunaliella Salina Extract, Jojoba Seed Extract, Camellia Sinensis Leaf Extract, Pistacia Lentiscus Gum, Echinacea Angustifolia Extract, Commiphora Mukul Extract Resin, Hydrogenated Polydecene, Dimethicone, Centella Asiatica Extract, Tetrahexyldecyl Ascorbate, Octyldodecyl Oleate, Rice Bran Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Helianthus Annuus Extract Sunflower Extract, Retinyl Palmitate, Tocopherol, Tocopheryl Acetate, Ubiquinone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- France: https://lovi.care/skincare/fr/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/nu-skin/ageloc-tru-face-essence-ultra/for/combination-skin