# No7 Protect & Perfect Intense Advanced Serum for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [No7](https://lovi.care/skincare/brands/no7)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other serums fit it better.

## Why this fit

- Offers moderate benefits for dry and sensitive skin, as sodium hyaluronate and dimethicone provide essential hydration and emollient action to combat dryness and flakiness.
- The presence of Palmitoyl Oligopeptide and Palmitoyl Tetrapeptide-7 supports skin elasticity and helps minimize fine lines, offering general anti-aging advantages.
- The product is safe for your dry and sensitive skin, with no harsh ingredients that could cause irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/mature-skin): Average
- [Dry sensitive skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Sodium Ascorbyl Phosphate, Retinyl Palmitate, Acetyl Dipeptide-1 Cetyl Ester, Hydrolyzed Rice Protein, Dimethicone

## What the research says

- Petrolatum-based skin protectants demonstrated protection against irritants and maceration while providing skin hydration, whereas dimethicone and zinc oxide products showed varying or limited performance across parameters among 18 healthy volunteers compared to positive and negative controls. ([Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/))
- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Over-the-counter retinol products provided only weak evidence for a mild ameliorating effect on fine facial skin wrinkle lines in randomized, double-blind, vehicle-controlled trials, and major methodological flaws call the validity of positive results into question. ([The Journal of Clinical and Aesthetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/34980969/))
- A cosmetic niacinamide/peptide/retinyl propionate regimen significantly improved periorbital wrinkle appearance relative to a 0.02% tretinoin regimen at 8 weeks with comparable benefits at 24 weeks, while demonstrating significantly better tolerability in 196 women. ([The British Journal of Dermatology, 2010](https://pubmed.ncbi.nlm.nih.gov/20374604/))
- A novel triple-active cosmetic formulation containing 4-hexylresorcinol, retinyl propionate, and niacinamide improved the visual appearance of photoageing similarly to 0.02% tretinoin and reversed a consensus gene signature associated with ageing in female adults while causing less skin irritation. ([International Journal of Cosmetic Science, 2024](https://pubmed.ncbi.nlm.nih.gov/38685700/))
- Cosmetic products containing 4-t-butylcyclohexanol demonstrated a faster and more pronounced soothing effect on capsaicin-induced burning compared to those containing acetyl dipeptide-1 cetyl ester in volunteers with sensitive skin. ([Journal of the European Academy of Dermatology and Venereology, 2016](https://pubmed.ncbi.nlm.nih.gov/26805418/))
- Rice protein hydrolysate and its characteristic peptides Leu-Leu-Lys, Leu-Pro-Lys, and pyroGlu-Lys reduced melanin content, tyrosinase activity, and ROS production in UVB-induced human epidermal melanocyte PIG1 cells by regulating the JNK/Β-Trcp/NFΗB-p65/MITF signaling pathway and lowering TRP-1 and TRP-2 expression. ([Food & Function, 2020](https://pubmed.ncbi.nlm.nih.gov/32955075/))
- Wearing an N95 mask alone compared to using dimethicone cream or hydrocolloid dressing caused more adverse skin reactions among 73 military health care workers, with no significant differences in fit test failure rates between groups. ([Military Medicine, 2024](https://pubmed.ncbi.nlm.nih.gov/38771104/))
- Treatment with a moisturizer containing dimethicone and glycerine increased epidermal thickness by 0.019 mm, improved barrier function by decreasing transepidermal water loss by 13%, decreased melanin intensity, and induced keratins 6 and 16 in fifteen women with moderately photoaged forearms. ([Clinical and Experimental Dermatology, 2007](https://pubmed.ncbi.nlm.nih.gov/17137484/))
- Externally applied substances such as ceramides, hyaluronic acid, licorice extracts, dimethicone, petrolatum, and paraffin wax treat skin disease resulting from damage to the skin barrier. ([Clinics in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22507050/))

## What reviewers say

Based on a very large amount of data, users with aging, dry, or combination skin frequently praise this serum for its silky texture and ability to instantly smooth and hydrate the skin. While many report visible improvements in fine lines and overall radiance after consistent use, results regarding deep wrinkles are mixed, with some users seeing significant firming and others noticing little change.

- Liked: Instant skin smoothing (mostly mentioned)
- Liked: Silky, lightweight texture (mostly mentioned)
- Liked: Quick absorption (often mentioned)
- Liked: Hydration and radiance (sometimes noted)
- Liked: Reduces fine lines (sometimes noted)
- Disliked: Lack of visible results (sometimes noted)
- Disliked: Silicone-heavy feel (sometimes noted)
- Disliked: Greasiness (rarely noted)
- Disliked: Packaging issues (rarely noted)
- Disliked: Skin irritation (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does No7 Protect & Perfect work for dry sensitive skin?

No7 Protect & Perfect Intense Advanced Serum works moderately well for dry sensitive skin by offering basic hydration and smoothing fine lines with peptides. Because it is an average fit, dry and sensitive skin needs a product with maximum beneficial hydrating and nourishing components, ceramides, and multiple forms of vitamin C to lock in moisture and protect the skin barrier safely.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Which ingredients make this serum a good fit for dry sensitive skin?

Sodium hyaluronate and dimethicone make this serum a good fit for dry and sensitive skin because they provide essential moisture and help smooth dryness and flakiness. To work best for this skin type, a treatment of this type needs rich hydrating and nourishing ingredients, skin barrier support, and a gentle formula that delivers deep moisture without irritation.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/)

### What does Vitamin C do for dry sensitive skin?

Vitamin C helps soothe and protect dry, sensitive skin by fighting oxidative stress and supporting the skin barrier. It is unlikely to cause irritation and may improve skin smoothness while keeping the skin calm.
Sources: [Experimental Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30698879/), [Antioxidants, 2024](https://pubmed.ncbi.nlm.nih.gov/38397772/)

### What does Retinyl Palmitate do for dry sensitive skin?

Retinyl palmitate helps smooth fine lines and improve dryness on dry sensitive skin while being gentle and causing minimal irritation. It works best when paired with soothing and hydrating ingredients to keep the skin calm and comfortable.
Sources: [Journal of Cosmetic Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23438139/), [International Journal of Nanomedicine, 2021](https://pubmed.ncbi.nlm.nih.gov/34211271/)

### Where does this serum go in a skincare routine for dry sensitive skin?

This serum goes in the evening routine after your toner and before your moisturizer. A product for this skin needs soothing ingredients and extra moisture from sodium hyaluronate and dimethicone to combat dryness and flakiness safely.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first, letting it absorb, and then following with your retinol product to help keep your skin comfortable. This product includes soothing and smoothing ingredients, but dry and sensitive skin needs formulas rich in extra hydration and calming agents to prevent irritation.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### How often should I use this serum?

This treatment is intended for evening use, starting once a week and gradually increasing as your skin adjusts safely. To work best for dry and sensitive skin, a product of this type needs rich hydrators and soothing agents that lock in moisture and prevent irritation.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### Can this serum clog pores, cause breakouts or purging for dry sensitive skin?

This serum is unlikely to cause breakouts or clogged pores on dry sensitive skin, as it has a very low risk of irritation and greasiness. To care for this skin type properly, a product of this type needs extra hydrating ingredients and gentle moisture-locking agents to keep the skin soft and smooth without feeling heavy.
Sources: [Ostomy/wound Management, 2005](https://pubmed.ncbi.nlm.nih.gov/16439809/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — $39.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — $53.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — $16.75 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — $16.97 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $37.99 (https://www.amazon.com/dp/B07CKM5L1T?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Acetyl Dipeptide-1 Cetyl Ester, Water, Butylene Glycol, Carbomer, Cetyl Peg Ppg-10 1 Dimethicone, Dimethicone, Dimethicone Crosspolymer, Ethylhexylglycerin, Ethylparaben, Glycerin, Hexyl Laurate, Hydrolyzed Rice Protein, Hydroxyethylcellulose, Magnesium Sulfate, Medicago Sativa Extract, Methylparaben, Morus Alba Leaf Extract, Palmitoyl Oligopeptide, Palmitoyl Tetrapeptide-7, Panax Ginseng Root Extract, Peg Ppg-18 18 Dimethicone, Phenoxyethanol, Polyglyceryl-4 Isostearate, Polysorbate 20, Propylene Glycol, Retinyl Palmitate, Sodium Ascorbyl Phosphate, Sodium Benzoate, Sodium Hyaluronate, Sorbitan Laurate, Tocopherol, Tocopheryl Acetate
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/no7/protect-and-perfect-intense-advanced-serum/for/dry-sensitive-skin