# NIOD Modulating Glucosides for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [NIOD](https://lovi.care/skincare/brands/niod)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other serums fit it better.

## Why this fit

- Offers moderate soothing and calming effects for your oily skin, with Bisabolol and Epigallocatechin Gallatyl Glucoside helping to reduce redness and irritation. Squalane and Glycerin provide general hydration, which is supportive but not directly targeted at your oily shine.
- The formula is highly suitable for oily skin due to the antioxidant and anti-inflammatory actions of Epigallocatechin Gallatyl Glucoside and Rosmarinyl Glucoside.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the presence of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-acne-prone-skin): High

## Key ingredients

Glucosides, Squalane, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Palmitoyl Tripeptide-8

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles. ([The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))

## What reviewers say

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

- Liked: Calms sensitive skin (mostly mentioned)
- Liked: Reduces skin redness (often mentioned)
- Liked: Buffers active irritation (sometimes noted)
- Liked: Strengthens skin barrier (sometimes noted)
- Disliked: Inconvenient packaging (sometimes noted)
- Disliked: Subtle for normal skin (sometimes noted)
- Disliked: Can cause breakouts (rarely noted)
- Disliked: Unappealing scent (rarely noted)

## How to apply

- Use this serum in your PM routine. Start by applying it 3 times a week and build up to daily use if your skin tolerates it well.
- Apply the serum after cleansing and toning, but right before your moisturizer for the best results.
- Gently press 2-3 drops of the serum into your skin. Let it absorb ⏱ for a minute before applying the next product.
- Apply the serum on clean and dry skin since your skin is not sensitive and you want to target oily shine. This helps control excess oil throughout the night.
- Avoid the delicate eye area and do a patch test before using the serum for the very first time.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### How well does NIOD Modulating Glucosides work for oily skin?

NIOD Modulating Glucosides works moderately well for oily skin by offering soothing and calming effects with ingredients like bisabolol and epigallocatechin gallatyl glucoside, while squalane and glycerin provide general hydration that is supportive rather than directly targeted at oily shine. This treatment needs ingredients like niacinamide, ferulic acid, and zinc PCA to control sebum production and manage oily shine while addressing enlarged pores.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for oily skin?

This serum fits your oily skin with bisabolol and epigallocatechin gallatyl glucoside, which help calm redness and irritation, alongside squalane and glycerin for general hydration. To better fit oily skin, a product of this type needs ingredients like niacinamide, zinc PCA, and ferulic acid that control sebum production and manage oily shine.

### What do Glucosides do for oily skin?

Glyceryl glucoside helps balance moisture levels and keeps oily skin feeling soft and smooth without adding heavy oils. For oily skin, a product of this type needs lightweight hydrators and ingredients that support the skin barrier while controlling excess shine.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### What does Squalane do for oily skin?

Squalane helps keep oily skin soft and smooth without feeling heavy, though oxidized forms may sometimes trigger irritation. To work well for oily skin, this type of product needs lightweight, non-clogging ingredients that balance moisture without adding excess grease.
Sources: [The Journal of Investigative Dermatology, 2006](https://pubmed.ncbi.nlm.nih.gov/16778793/)

### Where does it go in a skincare routine for oily skin?

This treatment goes in the evening routine, applied after cleansing and before your moisturizer. It is unlikely to cause irritation for your oily skin due to its soothing ingredients, though oily skin ultimately works best with products that also target excess shine.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside a retinol, applying this soothing serum after your retinol or choosing a product that specifically targets excess oil and shine for better results.
Sources: [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38102855/)

### How often should I use it?

You can use this treatment in your evening routine. Oily skin also needs lightweight hydration and oil-controlling ingredients like niacinamide or salicylic acid.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This treatment is unlikely to clog pores or cause breakouts for oily skin, as it has an excellent safety profile without harsh ingredients. Reviewers occasionally mention breakouts, and oily skin of this type needs lightweight, balancing ingredients that control excess shine without heavy moisture.

### Is it fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for oily skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/oily-skin) — Superior fit — $28.88 at Amazon
- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/oily-skin) — High fit — $39.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/niod/modulating-glucosides/for/oily-skin
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