# NIOD Modulating Glucosides for dry sensitive skin

**Lovi Fit: High fit for dry sensitive skin.**
Dry Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [NIOD](https://lovi.care/skincare/brands/niod)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry sensitive skin; a few serums fit it even better.

## Why this fit

- Offers excellent soothing and anti-redness effects for your sensitive dry skin, as Bisabolol and Tasmannia Lanceolata Leaf Extract Fruit work to calm irritation and reduce redness.
- The inclusion of Squalane and Glycerin provides essential hydration, addressing your dry or flaky skin concerns by smoothing intercellular lipids and drawing water into the skin.
- This formula is safe for your sensitive skin, containing no harsh ingredients and featuring soothing components that minimize the risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-sensitive-skin): High (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/p/niod/modulating-glucosides/for/oily-acne-prone-skin): High

## Key ingredients

Glucosides, Squalane, Superoxide Dismutase, Epigallocatechin Gallatyl Glucoside, Palmitoyl Tripeptide-8

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical application of glyceryl glucoside significantly increased AQP3 mRNA levels and reduced transepidermal water loss compared with vehicle-controlled areas in volunteer subjects. ([Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/))
- Topical oil-in-water and water-in-oil emulsions containing glyceryl glucoside, natural moisturizing factors, and ceramide significantly improved skin hydration and barrier function while reducing visible dryness and tactile roughness in subjects with very dry skin compared to untreated sites and vehicles. ([The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/))
- Topical application of TAT-SOD significantly suppresses UVB-induced erythema formation, blood flow rise, and apoptotic sunburn cell formation in human volunteers compared to a vehicle control. ([European Journal of Pharmaceutics and Biopharmaceutics, 2016](https://pubmed.ncbi.nlm.nih.gov/27460952/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))
- Topical treatment with the synthetic SOD/catalase mimetic EUK-134 reduced lipid peroxide levels both at baseline on non-irradiated human skin and at the surface of UVA-exposed skin when applied before or after irradiation, compared to controls. ([International Journal of Cosmetic Science, 2004](https://pubmed.ncbi.nlm.nih.gov/18492138/))
- Topical superoxide dismutase formulations maintained physical stability and enzymatic activity for 6 months at 4 and 30 degrees C, and effectively inhibited UVB-induced skin erythema for 48 hours, whereas formulations combined with alpha-tocopherol were unstable. ([European Journal of Pharmaceutics and Biopharmaceutics, 2007](https://pubmed.ncbi.nlm.nih.gov/17196809/))
- Superoxide dismutase 3 suppressed Propionibacterium acnes-induced skin inflammation by inhibiting the TLR2/p38/NF-κB axis and NLRP3 inflammasome activation in vitro and in vivo. ([Scientific Reports, 2018](https://pubmed.ncbi.nlm.nih.gov/29507345/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))

## What reviewers say

This serum is highly praised for its ability to calm sensitive, reactive, and irritated skin, with users frequently reporting significant improvements in redness, stinging, and compromised skin barriers. It is a popular choice for those recovering from aesthetic treatments or harsh active ingredients. Some users with normal skin may find the benefits less noticeable or the texture slightly heavy.

- Liked: Calms sensitive skin (mostly mentioned)
- Liked: Reduces skin redness (often mentioned)
- Liked: Buffers active irritation (sometimes noted)
- Liked: Strengthens skin barrier (sometimes noted)
- Disliked: Inconvenient packaging (sometimes noted)
- Disliked: Subtle for normal skin (sometimes noted)
- Disliked: Can cause breakouts (rarely noted)
- Disliked: Unappealing scent (rarely noted)

## How to apply

- Use this PM routine for your evening skincare. Start using the serum 3 times a week and increase to daily use if your skin feels comfortable.
- Apply the serum after cleansing and toner, but right before your moisturizer. This step locks in deep hydration for dry skin.
- Gently press 2-3 drops of the serum into your skin using your palms. Let it absorb completely for a minute ⏱ before applying your next product.
- Since your skin is sensitive, apply the serum on completely dry skin for better tolerance and less irritation.
- Avoid the sensitive eye area during application. Always do a patch test before your first use to ensure your skin reacts well.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes NIOD Modulating Glucosides a great fit for dry sensitive skin?

NIOD Modulating Glucosides is a great fit because ingredients like bisabolol and Tasmanian pepperberry calm irritation and reduce redness. Meanwhile, squalane and glycerin draw in water and smooth dry skin, and the formula contains no harsh ingredients to keep your sensitive skin safe from irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for dry sensitive skin?

This treatment is a great fit for your dry sensitive skin because it contains bisabolol and tasmannia lanceolata leaf extract fruit to calm irritation and reduce redness, alongside squalane and glycerin to draw in moisture and smooth dry areas.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What do Glucosides do for dry sensitive skin?

Glucosides help keep dry sensitive skin soft and smooth by boosting moisture levels and reducing water loss. They improve how well the skin barrier holds onto hydration, which helps calm visible dryness and rough spots.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22584263/), [The Journal of Clinical and Aesthetic Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22916312/)

### What does Squalane do for dry sensitive skin?

Squalane helps keep dry sensitive skin soft and smooth by locking in moisture and calming irritation without causing flare-ups. It is unlikely to cause redness or discomfort, making it a gentle choice that supports the skin barrier. This type of skin needs ingredients that deeply hydrate and soothe, such as plant oils and antioxidants.
Sources: [International Journal of Molecular Sciences, 2017](https://pubmed.ncbi.nlm.nih.gov/29280987/), [Molecules, 2009](https://pubmed.ncbi.nlm.nih.gov/19169201/)

### Where does this treatment go in a skincare routine for dry sensitive skin?

This treatment goes in your evening routine, applied after your cleanser and soothing toner and before your moisturizer. Putting treatments in the evening helps keep your skin safe around sun exposure while providing effective care.

### Can I use this treatment with retinol, and in what order?

You can use this treatment with retinol by applying it after your retinol to help calm irritation and keep dry skin comfortable. Its soothing ingredients and gentle formula minimize the risk of redness when pairing active products.

### How often should I use this treatment?

Use this treatment in your evening routine. It is a great fit for dry sensitive skin because it helps calm irritation and provides essential hydration.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Can this treatment clog pores, cause breakouts or purging for dry sensitive skin?

This treatment is unlikely to clog pores or cause breakouts for dry sensitive skin. Reviewers rarely report breakouts from this formula, and its soothing ingredients help keep irritation low.

### Is this treatment fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (benzyl alcohol).

## Alternatives for dry sensitive skin

- [SkinCeuticals C E Ferulic](https://lovi.care/skincare/p/skinceuticals/c-e-ferulic/for/dry-sensitive-skin) — Superior fit — $39.99 at Amazon
- [Paula's Choice RESIST Super Antioxidant Concentrate Serum](https://lovi.care/skincare/p/paula-s-choice/resist-super-antioxidant-concentrate-serum/for/dry-sensitive-skin) — Superior fit — $53.00 at Amazon
- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/dry-sensitive-skin) — Superior fit — $16.75 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — $16.97 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Squalane, Isodecyl Neopentanoate, Glycerin, Caprylic Capric Triglyceride, Pentylene Glycol, Propanediol, Hexyldecanol, Bisabolol, Butylene Glycol, Epigallocatechin Gallatyl Glucoside, Rosmarinyl Glucoside, Caffeyl Glucoside, Gallyl Glucoside, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Hydroxymethoxyphenyl Decanone, 4-T-Butylcyclohexanol, Cetylhydroxyproline Palmitamide, Hydroxyphenyl Propamidobenzoic Acid, Palmitoyl Tripeptide-8, Superoxide Dismutase, Sodium Pca, Pca, Arginine, Glycine, Alanine, Serine, Valine, Isoleucine, Proline, Threonine, Histidine, Phenylalanine, Aspartic Acid, Sodium Lactate, Mirabilis Jalapa Callus Extract, Tasmannia Lanceolata Leaf Extract Fruit, Zingiber Officinale Root Extract, Curculigo Orchioides Root Extract, Isochrysis Galbana Extract, Brassica Campestris Sterols, Stearic Acid, Dextran, Isoceteth-20, Polyacrylate Crosspolymer-6, Xanthan Gum, Tocopherol, Propyl Gallate, Tromethamine, Dehydroacetic Acid, 1,2-Hexanediol, Benzyl Alcohol, Phenoxyethanol, Caprylyl Glycol
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

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## This page in other countries

- United States: https://lovi.care/skincare/p/niod/modulating-glucosides/for/dry-sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/niod/modulating-glucosides/for/dry-sensitive-skin
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