NEOGEN Dermalogy Day-Light Protection Airy Sunscreen for combination skin

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Questions and answers

What the research says

• Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate.

  Contemporary Clinical Trials Communications, 2021

• Vitamin E in O/W and W/O emulsions significantly increased stratum corneum hydration and enhanced water-binding capacity, with an optimum concentration of 5%.

  Arzneimittel-Forschung, 1998

• Co-encapsulation of alpha-tocopherol and alpha-tocopheryl acetate in nanostructured lipid carrier gel formulations significantly enhanced moisture retention up to 68% and improved skin elasticity in human volunteers compared to a solution gel.

  Scientific Reports, 2025

• Encapsulating avobenzone in low-porosity TiO2-embedded mesoporous silica (TiO2/SBA-S) reduced cutaneous avobenzone absorption from 0.76 to 0.50 nmol/mg while providing effective pollutant adsorbability, UVA protection, and a two- to three-fold reduction in photoaged skin cytokines/chemokines compared to the non-treatment control.

  European Journal of Pharmaceutical Sciences, 2023

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• Encapsulation of ethylhexyl methoxycinnamate and butyl methoxydibenzoylmethane in lipid microparticles significantly reduced their in vivo human skin penetration compared to nonencapsulated filters.

  Skin Pharmacology and Physiology, 2011

• Microencapsulation of the BMDBM/HP-beta-CD complex in lipid microparticles significantly decreased the percutaneous penetration of the UV filter into the stratum corneum of human volunteers compared to the non-encapsulated sunscreen agent.

  Journal of Pharmaceutical and Biomedical Analysis, 2011

• Following human skin application of an O/W emulsion containing 2% BMDBM loaded in lipospheres, 15% of the sunscreen accumulated in the uppermost layers of the stratum corneum without remarkably modifying skin permeation compared to unencapsulated sunscreen.

  Skin Pharmacology and Physiology, 2008

• Incorporating rosmarinic acid into sunscreens enhanced the in vivo SPF of octocrylene by over 157% and reduced lipid peroxidation in the human stratum corneum.

  Antioxidants, 2025

• The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.

  Archives of Dermatological Research, 2024

• Early application of sunscreen after ablative fractional skin resurfacing significantly increased the sensitization rate of the UV-filter, octocrylene, and the sunscreen compared to intact skin.

  The Journal of Dermatological Treatment, 2015

• Dermal application of a sunscreen containing 10% homosalate in four volunteers resulted in delayed elimination with terminal half-times around 24 h and a bioavailability of cis-homosalate a factor of 2 lower than trans-homosalate, while metabolite ratios supported using oral-route urinary excretion fractions for dermal exposure assessments.

  Archives of Toxicology, 2024

• Homosalate exhibited the highest permeation among tested filters with a relative permeability rate of 4.2% and a depth of 60 um, and specific thickeners and emulsifiers successfully reduced its permeation without inhibiting the skin permeation of niacinamide.

  Photodermatology, Photoimmunology & Photomedicine, 2026

• An online-SPE-LC-MS/MS method successfully quantified specific urinary homosalate metabolites for up to 96 hours after dermal sunscreen application in a volunteer and detected metabolites exclusively in three German pilot participants who had used sunscreen within five days.

  Analytica Chimica Acta, 2021

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical steroid withdrawal is driven by excess mitochondrial NAD+ metabolism that can be successfully targeted using complex I-inhibiting interventions such as metformin and berberine.

  The Journal of Investigative Dermatology, 2025

• Topical steroid withdrawal presents as a distinct dermatopathology characterized by burning, flushing, thermodysregulation, and elevated mitochondrial NAD+ oxidation, which can be improved by targeting complex I with metformin or berberine.

  MedRxiv, 2024

• Hydroxypropyl methylcellulose hydrogel formulations of berberine chloride-loaded escinosomes increased skin residence time and transdermal permeability while maintaining high safety and biocompatibility without skin irritation.

  International Journal of Biological Macromolecules, 2020

Ingredients

Water, Octocrylene, Homosalate, Isododecane, Dipropylene Glycol, Silica, Avobenzone, 1,2-Hexanediol, Octyldodeceth-16, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Tromethamine, Ethylhexylglycerin, Tocopheryl Acetate, Coptis Japonica Extract, Butylene Glycol, Xanthan Gum, Citrus Aurantium Dulcis Peel Oil, Litsea Cubeba Oil Fruit, Bergamot Oil Fruit, Pelargonium Graveolens Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Melaleuca Alternifolia Tree Oil Leaf, Citrus Aurantifolia Oil, Clove Oil Leaf, Camphor Oil Bark, Maltodextrin, Persea Gratissima Fruit Extract Avocado Fruit Extract, Oenothera Biennis Flower Extract, Pinus Palustris Leaf Extract, Ulmus Davidiana Root Extract, Pueraria Lobata Root Extract, Lemon Fruit Extract, Glycerin, Rosa Damascena Extract, Lippia Citriodora Leaf Extract, Adansonia Digitata Leaf Extract, Rubus Idaeus Fruit Extract Raspberry Fruit Extract, Portulaca Oleracea Extract, Blueberry Fruit Extract, Achillea Millefolium Extract, Arnica Montana Flower Extract, Aloe Barbadensis Leaf Extract, Artemisia Capillaris Extract, Euterpe Oleracea Fruit Extract, Phellinus Linteus Extract, Sodium Hyaluronate, Hibiscus Sabdariffa Flower Extract, Beta-Glucan, Citral, Citronellol, Limonene, Geraniol, Linalool

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.