# Natura Bissé Diamond Extreme for mature skin

**Lovi Fit: Superior fit for mature skin.**
Normal Skin Fit: High · Effectiveness: Superior · Safety: Excellent.

Page: https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Natura Bissé](https://lovi.care/skincare/brands/natura-bisse)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

One of the best moisturizers for mature skin.

## Why this fit

- Excellent for your normal skin, this formula leverages Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7 to effectively boost collagen synthesis and improve skin elasticity, addressing your concerns about wrinkles and fine lines. Shea butter and glycerin provide superior hydration and emollient action, reinforcing your skin's natural barrier.
- The inclusion of rosemary leaf extract and amaranthus caudatus seed extract further enhances the product's soothing and antioxidant properties, complementing the primary anti-aging benefits.
- This product is safe for your skin, with no reported irritation risks due to its gentle formulation and absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/mature-skin): Superior (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/oily-acne-prone-skin): Low

## Key ingredients

Amaranthus Caudatus Seed Extract, Butyrospermum Parkii Butter Shea Butter, Sodium Hyaluronate, Palmitoyl Tripeptide-1, Tocopherol

## What the research says

- A multi-modal methodology combining MALDI-MSI, in vivo RCM, echography, and histology revealed age-related decreases in extracellular matrix and epidermal-dermal junction proteins and undulation depth, while a blend of palmitoyl oligopeptide and palmitoyl tetrapeptide-7 improved subepidermal low-echogenic band thickness, density, and extracellular matrix structure compared to placebo. ([Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/))
- Chronomodulated daytime application of baicalin and nighttime application of palmitoyl tripeptide-1 synergistically improved skin luminance by 16.29%, nasolabial fold depth by -36.35%, and firmness by 24.35% in 30 female participants. ([Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A combination cream of stimu-tex AS and saccharide isomerate reduced erythema, increased skin capacitance, and reduced transepidermal water loss compared to placebo in 20 subjects after fractional CO2 laser procedure without causing serious adverse events. ([Lasers in Medical Science, 2025](https://pubmed.ncbi.nlm.nih.gov/41134387/))
- A single use of an alpha-tocopherol-enriched rinse-off product strongly increases alpha-tocopherol levels in skin barrier lipids maintained for at least 24 hours and significantly inhibits squalene photooxidation in human volunteers compared to a control product. ([Skin Pharmacology and Physiology, 2005](https://pubmed.ncbi.nlm.nih.gov/15608499/))
- Topical treatment with a mixed RetinSphere - vitamin E formulation significantly decreased lipid peroxidation levels and oxidized squalene percentage, reduced interleukin-1α concentration in lesional areas, and led to clinical improvement in 18 patients with mild comedonal acne. ([Journal of the European Academy of Dermatology and Venereology, 2014](https://pubmed.ncbi.nlm.nih.gov/24628899/))
- The investigated actives incorporated into alkyl polyglucoside emulsifier-stabilized creams showed no skin irritation and provided increased skin hydration and reduced transepidermal water loss in 76 healthy volunteers. ([Vojnosanitetski Pregled, 2016](https://pubmed.ncbi.nlm.nih.gov/29328637/))
- A skin barrier restoring cream with shea butter, silkflo, and vitamin E increased type I procollagen synthesis, enhanced antioxidant enzyme activity, decreased reactive oxygen species generation, and promoted hyaluronic acid production in H2O2-stimulated human keratinocyte cells compared to untreated cells. ([International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Palmitoyl tetrapeptide-7, acetyl hexapeptide-8, palmitoyl tripeptide-1, and palmitoyl tetrapeptide-10 significantly increased type III collagen levels in human dermal fibroblasts following UV exposure, with their combination demonstrating a greater effect in vitro and enhancing type I, III, and IV collagen levels in ex vivo skin tissues compared to individual components. ([International Journal of Cosmetic Science, 2026](https://pubmed.ncbi.nlm.nih.gov/42683869/))
- Topical application of an antioxidant serum containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented particulate matter-induced degradation of extracellular matrix components, inflammation, and oxidative stress in the skin of 15 female volunteers compared to untreated controls. ([Journal of Cosmetic Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40642809/))
- Dermatological products containing d-alpha tocopheryl acetate showed non-comedogenic potential with less than a 50% increase in microcomedones in 12 healthy male subjects compared to octyl palmitate. ([Contemporary Clinical Trials Communications, 2021](https://pubmed.ncbi.nlm.nih.gov/34471722/))
- Topical application of an antioxidant mix containing 15% ascorbic acid, 0.5% ferulic acid, and 1% tocopherol prevented PM and UV-induced skin barrier perturbation, lipid peroxidation, inflammatory markers, MMP9 activation, and Type I collagen loss in 15 healthy females compared to untreated exposed skin. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38590207/))

## What reviewers say

Based on a very large amount of data, users with mature, dry, and dull skin frequently report intense, long-lasting hydration and an immediate glow. Many users notice visibly softer fine lines and a plumped complexion. Some users mention that lifting and firming effects are subtle and require consistent, long-term use.

- Liked: Intense Hydration (mostly mentioned)
- Liked: Luxurious Texture (mostly mentioned)
- Disliked: High Price (mostly mentioned)
- Liked: Instant Radiance (often mentioned)
- Liked: Signature Scent (sometimes noted)
- Disliked: Strong Fragrance (sometimes noted)
- Disliked: Jar Packaging (rarely noted)
- Disliked: Subtle Firming Results (rarely noted)

## How to apply

- Use your moisturizer twice a day in your AM and PM routines. Apply it daily to help smooth fine lines.
- Apply this product after your toner and serum, but before your SPF in the morning. Follow your cleanser and toner steps to keep your skin balanced.
- Gently press a small amount into your face and neck. Avoid rubbing the skin too harshly to prevent extra tension.
- Apply the moisturizer on slightly damp skin to help lock in extra moisture. Clean skin helps the product absorb much more evenly.
- Avoid the sensitive eye area during application. Do a quick patch test before your very first use to stay safe.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Natura Bissé Diamond Extreme one of the best fits for mature skin?

This moisturizer is one of the best fits for mature skin because it uses peptides like Palmitoyl Tripeptide-1 to boost firmness and smooth fine lines. Shea butter and glycerin provide rich hydration to reinforce your natural barrier, while plant extracts add soothing and antioxidant benefits.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Which ingredients make this cream a good fit for mature skin?

This cream is a great fit for mature skin because it contains palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7, which help boost collagen and smooth out fine lines. It also includes shea butter and glycerin to keep your skin deeply hydrated and soft, while antioxidants like tocopherol help protect it.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### What does Amaranth Seed Extract do for mature skin?

Amaranth seed extract helps protect mature skin from UV damage and daily stress by fighting harmful oxidation and supporting healthy skin cells. This keeps the skin looking strong and smooth as it ages.
Sources: [International Journal of Molecular Sciences, 2023](https://pubmed.ncbi.nlm.nih.gov/37445970/)

### What does Butyrospermum Parkii Butter do for mature skin?

Butyrospermum Parkii Butter helps mature skin stay soft and smooth by supporting the skin barrier and keeping it moisturized. It may also help protect against environmental stress and improve overall skin appearance.
Sources: [Journal of Drugs in Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37556521/), [International Journal of Cosmetic Science, 2025](https://pubmed.ncbi.nlm.nih.gov/39528438/)

### Where does this cream go in a skincare routine for mature skin?

This cream is used as a moisturizer in your morning routine and as a final moisturizing treatment step in your evening routine. It helps keep mature skin soft and hydrated while supporting firmness.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol by applying it after your retinol treatment to help soothe the skin and lock in moisture. Using a barrier-supporting moisturizer alongside retinol helps improve your skin's comfort and reduces the likelihood of dryness or irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/)

### How often should I use this cream?

This moisturizing treatment is well suited for daily use to help keep mature skin soft and smooth. Applying it twice a day may help improve skin firmness, hydration, and the appearance of fine lines and wrinkles over time.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for mature skin?

This moisturizing treatment is unlikely to clog pores or cause breakouts for mature skin, as it features a gentle formulation without harsh ingredients that typically trigger irritation. It helps keep skin soft and smooth while supporting your natural barrier.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25817264/), [Journal of Cosmetic Dermatology, 2026](https://pubmed.ncbi.nlm.nih.gov/41527525/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on your body, as its gentle formulation is well tolerated by delicate areas. Regular application of its peptides and hydrating ingredients helps smooth fine lines and maintain moisture across different skin regions without causing irritation.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It contains fragrance (parfum, linalool, limonene, coumarin, geraniol, and citronellol) and drying alcohol (alcohol denat).

## Alternatives for mature skin

- [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon
- [SKIN1004 Madagascar Centella Probio-Cica Enrich Cream](https://lovi.care/skincare/p/skin1004/madagascar-centella-probio-cica-enrich-cream/for/mature-skin) — Superior fit — $22.00 at Amazon
- [L'Occitane Immortelle Divine Cream](https://lovi.care/skincare/p/l-occitane/immortelle-divine-cream/for/mature-skin) — Superior fit — $120.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- SPF: [ISDIN Eryfotona Actinica SPF 50+](https://lovi.care/skincare/p/isdin/eryfotona-actinica-spf-50/for/mature-skin) — Superior fit — $46.00 at Amazon

## Where to buy

- Amazon.com: $420.00 (https://www.amazon.com/dp/B0BKLRMKZV?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 3 Nov 2026.

## Ingredients

Water, Pentaerythrityl Tetracaprylate Tetracaprate, Caprylic Capric Triglyceride, C12-20 Acid Peg-8 Ester, Propanediol, Cetearyl Ethylhexanoate, Hydrogenated Polydecene, Butyrospermum Parkii Butter Shea Butter, Amaranthus Caudatus Seed Extract, Mangifera Indica Seed Butter, Glyceryl Stearate, Glycerin, Butylene Glycol, Ceratonia Siliqua Fruit Extract, Inulin, Sodium Phytate, Phytosphingosine, C10-30 Cholesterol Lanosterol Esters, Pistacia Lentiscus Gum, Paeonia Albiflora Root Extract, Trehalose, Alpha-Glucan Oligosaccharide, Trichosanthes Kirilowii Root Extract, Leontopodium Alpinum Leaf Extract Flower, Pisum Sativum Extract, Rosamarinus Officinalis Leaf Extract Rosemary Leaf Extract, Artemia Extract, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Tocopherol, Glucose, Dimethicone, Tribehenin, Silica, Carbomer, Cetyl Phosphate, Polyacrylamide, Ceratonia Siliqua Gum, Ethylhexylglycerin, Octadecyl Di-T-Butyl-4-Hydroxyhydrocinnamate, C13-14 Isoparaffin, Sodium Hydroxide, Benzotriazolyl Dodecyl P-Cresol, Laureth-7, Sodium Lactate, Polysorbate 20, Sodium Citrate, Alcohol Denat, Citric Acid, Phenoxyethanol, Potassium Sorbate, Sodium Benzoate, Parfum, Linalool, Limonene, Coumarin, Geraniol, Citronellol, Alpha-Isomethyl Ionone
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/natura-bisse/diamond-extreme/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/natura-bisse/diamond-extreme/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/natura-bisse/diamond-extreme/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/natura-bisse/diamond-extreme/for/mature-skin
- France: https://lovi.care/skincare/fr/p/natura-bisse/diamond-extreme/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/natura-bisse/diamond-extreme/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/natura-bisse/diamond-extreme/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/natura-bisse/diamond-extreme/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/natura-bisse/diamond-extreme/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/natura-bisse/diamond-extreme/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/natura-bisse/diamond-extreme/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/natura-bisse/diamond-extreme/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/natura-bisse/diamond-extreme/for/mature-skin