# Murad Retinol Youth Renewal Night Cream for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Murad](https://lovi.care/skincare/brands/murad)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few moisturizers fit it even better.

## Why this fit

- Highly suitable for your oily skin, this product leverages niacinamide for seboregulation and retinol for desquamation regulation, effectively addressing oiliness and smoothing fine lines. Sodium hyaluronate and retinol work synergistically to provide excellent moisturizing and anti-aging effects, hydrating and smoothing your skin.
- While offering general skincare benefits like hydration and soothing for your oily and acne-prone skin, the formulation's primary focus is on anti-aging rather than directly targeting acne and blemishes.
- The safety profile is excellent, with no risks of irritation for your oily skin due to the absence of harsh ingredients and the inclusion of soothing components like niacinamide and hyaluronic acid.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Retinol, Niacinamide, Sodium Hyaluronate, Hydrolyzed Yeast Extract, Glycerin

## What the research says

- Topical 0.4% retinol significantly increased epidermal thickness, dermal vascularity, and extracellular matrix production by stimulating keratinocyte proliferation, endothelial cell proliferation, and fibroblast activation in naturally aged human skin compared to vehicle. ([International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/))
- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Topical bakuchiol 0.5% applied twice daily compared with retinol 0.5% applied daily significantly decreased wrinkle surface area and hyperpigmentation with no statistical difference between the compounds in 44 patients over 12 weeks, while retinol users reported more facial skin scaling and stinging. ([The British Journal of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/29947134/))
- Silicone particles encapsulating retinol increased its half-life by 9-fold and yielded 12-23% lower skin irritation in human subjects compared to Microsponge particles while maintaining biological activity. ([Journal of Controlled Release, 2018](https://pubmed.ncbi.nlm.nih.gov/29604311/))
- Topical stabilized retinol treatment induced HAS gene expression and increased hyaluronic acid production in human skin in vitro, ex vivo, and in vivo compared to vehicle. ([Archives of Dermatological Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28247017/))
- Topical application of all-trans-retinol induced epidermal thickening and increased retinoid binding protein expression similar to all-trans-retinoic acid in normal human skin, but without causing significant erythema or measurable retinoic acid levels. ([The Journal of Investigative Dermatology, 1995](https://pubmed.ncbi.nlm.nih.gov/7561157/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical moisturizers improved skin barrier function and surface moisture, while a postbiotic moisturizer with yeast extract uniquely supported microbiome balance and modulated biomarkers of skin barrier, structure, and inflammation in participants and ex vivo explants exposed to environmental aggressors. ([Journal of Clinical Medicine, 2023](https://pubmed.ncbi.nlm.nih.gov/37763018/))
- A maintenance therapy with a cosmeceutical formulation containing hydroxyphenoxy propionic acid, ellagic acid, yeast extract, and salicylic acid over 20 weeks significantly improved even skin tone, spot intensity, spot size, and overall hyperpigmentation in 33 healthy subjects with moderate facial dyspigmentation. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25844613/))
- A methanol yeast extract increases proliferation and migration while decreasing entrance into senescence and apoptosis phases in 3T3 fibroblast cells. ([Journal of Cosmetic Science, 2014](https://pubmed.ncbi.nlm.nih.gov/25898765/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))

## What reviewers say

Based on a very large amount of data, users report this night cream effectively smooths fine lines and improves skin texture without the harsh irritation often associated with retinol. Many praise its hydrating, lightweight formula for creating a plump and radiant complexion, though a subset of users with sensitive skin experienced dryness or breakouts.

- Liked: Gentle and hydrating (mostly mentioned)
- Liked: Luxurious texture (often mentioned)
- Liked: Visible anti-aging (often mentioned)
- Liked: Radiance and glow (sometimes noted)
- Disliked: High price point (sometimes noted)
- Disliked: Strong fragrance (sometimes noted)
- Disliked: Adverse reactions (rarely noted)
- Disliked: Packaging issues (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes Murad Retinol Youth Renewal Night Cream a great fit for oily acne-prone skin?

This cream is a great fit for your oily, acne-prone skin because it combines niacinamide to balance oil and retinol to smooth fine lines. It also includes sodium hyaluronate and glycerin to keep your skin hydrated and soft without clogging pores.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

This cream is a great fit for your oily skin because it uses niacinamide to help balance oil and retinol to smooth fine lines. It also includes sodium hyaluronate and glycerin to keep your skin hydrated and soft without feeling heavy.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### What does Retinol do for oily acne-prone skin?

Retinol helps oily acne-prone skin by clearing up breakouts and smoothing the skin, though it may occasionally cause some mild scaling or stinging. This ingredient works by addressing the root causes of acne, making it a reliable choice for keeping pores clear and skin smooth.
Sources: [American Journal of Clinical Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30674002/), [Journal of Drugs in Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30586483/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this cream go in a skincare routine for oily acne-prone skin?

This treatment goes in the evening routine after cleansing and before your moisturizer. It is unlikely to cause irritation for your oily skin and helps smooth fine lines.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can I use this cream with vitamin C, and in what order?

You can use this cream in your evening routine, but it is best to use vitamin C in the morning to avoid mixing strong actives at the same time. Using them separately helps prevent skin irritation while still keeping your skin smooth and bright.

### How often should I use this cream?

Apply this treatment cream in your evening routine. Using it at night is best for simplicity and extra safety around sun exposure.

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is a great fit for your oily skin and is unlikely to cause irritation, but because it contains retinol, it may cause initial purging as it helps smooth fine lines and renew your skin. While it offers good hydration and soothing benefits, its main focus is anti-aging rather than directly treating acne and blemishes.
Sources: [International Journal of Cosmetic Science, 2017](https://pubmed.ncbi.nlm.nih.gov/27261203/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes, where the skin is particularly thin, as it features hydrating ingredients like sodium hyaluronate and retinol that help smooth fine lines. While it has an excellent safety profile, applying it all over the body may be impractical due to its specialized anti-aging focus and size.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/), [Polymers, 2023](https://pubmed.ncbi.nlm.nih.gov/37896378/)

### Is this cream fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (citronellol and parfum). Cetyl alcohol and oleyl alcohol are fatty alcohols, which soften the skin.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — $15.88 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — $15.50 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — $49.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — $25.99 at Amazon

## Where to buy

- Amazon.com: $94.00 (https://www.amazon.com/dp/B081ZQH733?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Isostearyl Hydroxystearate, Niacinamide, Propanediol, Caprylic Capric Triglyceride, C14-22 Alcohols, Polymethylsilsesquioxane, Dimethicone, Cetyl Alcohol, Glyceryl Stearate, Hydrolyzed Yeast Extract, Isopropyl Palmitate, Retinol, Retinyl Propionate, Oleyl Alcohol, Sodium Hyaluronate, Serine, Hexyldecanol, Glycine Soja Extract Soybean Extract, Tocopheryl Acetate, Glycine Soja Soybean Sterols, Urea, Yeast Amino Acids, Trehalose, Inositol, Taurine, Betaine, Glycerin, Polyglucuronic Acid, C12-20 Alkyl Glucoside, Yam Root Extract, Pentylene Glycol, Glyceryl Polyacrylate, Algin, Caprylyl Glycol, Swertia Chirata Extract, Lecithin, Pullulan, Disodium Phosphate, Potassium Phosphate, Peg-75 Stearate, Ceteth-20, Steareth-20, Cetyl Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Picolinamide, Disodium Edta, Sodium Hydroxide, Hexylene Glycol, Sodium Benzotriazolyl Butylphenol Sulfonate, Ammonium Acryloyldimethyltaurate Vp Copolymer, Yellow 5 Ci 19140, Red 4 Ci 14700, Alpha-Isomethyl Ionone, Citronellol, Parfum
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/murad/retinol-youth-renewal-night-cream/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/murad/retinol-youth-renewal-night-cream/for/oily-acne-prone-skin
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