# MISSHA Super Aqua Ultra Hyalron Ampoule for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [MISSHA](https://lovi.care/skincare/brands/missha)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration for your oily skin, with niacinamide helping to regulate oil production and multiple forms of hyaluronic acid providing deep moisturization. While beneficial for general hydration and oil control, the formula lacks specific ingredients to target acne, blemishes, and breakouts.
- The product is safe for your oily skin, as it contains soothing ingredients like Camellia Sinensis Leaf Water and Anthemis Nobilis Oil Flower, and avoids harsh or prohibited substances.
- This formulation provides excellent moisturizing treatment due to the presence of multiple forms of hyaluronic acid, such as sodium hyaluronate and hydrolyzed hyaluronic acid, in concentrations that provide deep hydration.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

10x Hyaluronic Acid, Niacinamide, Avena Sativa Kernel Extract Oat Kernel Extract, Cynara Scolymus Leaf Extract, Beta-Glucan

## What the research says

- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- A moisturizing cream containing 2% l-carnitine and 5% EGCG significantly reduced sebum levels and improved skin hydration in ninety subjects with seborrhea over 4 weeks, showing greater anti-sebum efficacy in the combination group compared to the l-carnitine group alone. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37194909/))
- Profhilo treatment led to significant improvements in superficial skin hydration and transepidermal water loss over time in Chinese females, while demonstrating good product tolerability. ([Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/))
- Profhilo gel combined with Dysport Botox significantly improved skin hydration, skin thickness, and GAIS scores compared to Dysport Botox injection alone in 19 participants seeking neck rejuvenation. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/35775872/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- A repair cream containing Rhealba oat plantlets extract, l-ALA-l-GLU dipeptide, and hyaluronic acid provided immediate relief and was judged by doctors as good or very good in 96.8% of cases for wound healing in 2,363 patients following dermatological acts. ([Clinical, Cosmetic and Investigational Dermatology, 2018](https://pubmed.ncbi.nlm.nih.gov/30519069/))
- Topically applied Avena sativa and Avena Rhealba oatmeal extracts significantly reduced skin irritation parameters including a* parameter increase and blood flow increase compared to vehicle in 12 healthy individuals subjected to the sodium lauryl sulfate irritation model. ([Skin Pharmacology and Applied Skin Physiology, 2002](https://pubmed.ncbi.nlm.nih.gov/11867969/))
- Colloidal oat extracts diminished pro-inflammatory cytokines in vitro and colloidal oat lotion improved skin dryness, scaling, roughness, and itch intensity in healthy female subjects compared to baseline. ([Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25607907/))
- An artichoke extract cosmetic formulation enhanced skin roughness by 19.74% and elasticity by 11.45% in human subjects compared to a placebo cream, alongside exhibiting antioxidant, anti-inflammatory, and anti-aging cellular effects. ([Molecules, 2018](https://pubmed.ncbi.nlm.nih.gov/30360471/))
- Luteolin inhibited the mRNA expression of antimicrobial peptides and increased cornified envelope proteins in TNF-alpha/IL-17A/IFN-gamma-stimulated HaCaT cells by regulating the TRAF6/IkappaB/NF-kappaB signaling pathway. ([Food Science and Biotechnology, 2025](https://pubmed.ncbi.nlm.nih.gov/40655288/))
- Antioxidants and luteolin topically applied decrease UV-B induced apoptosis and downregulate pro-inflammatory cytokines in kindler syndrome keratinocyte cultures. ([Human Molecular Genetics, 2016](https://pubmed.ncbi.nlm.nih.gov/27798104/))
- Skin care regimens containing beta-glucan improved hemoglobin index, skin hydration, and transepidermal water loss compared to vehicle control in 20 patients undergoing fractional laser therapy. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33128496/))
- Treatment with topical formulations containing beta-glucan combined with nanofractional radiofrequency plus magnetic nanofractional radiofrequency showed the best efficacy and was tolerable and effective in Chinese women with abdominal stretch marks compared to control groups. ([Dermatology and Therapy, 2023](https://pubmed.ncbi.nlm.nih.gov/37171578/))
- Topical beta-glucan mildly improved striae gravidarum, 1565-nm non-ablative fractional laser showed better results than topical beta-glucan, and the combined strategy further improved striae gravidarum atrophy compared to single treatment. ([The Journal of Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35570397/))

## Why other moisturizers fit oily acne-prone skin better

- Gluconolactone 14% solution significantly improved mild to moderate acne by reducing inflamed and non-inflamed lesions similarly to 5% benzoyl peroxide, but with fewer side-effects in 150 patients. ([The Australasian Journal of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1303072/))
- A peel-off facial mask containing myoinositol and trehalose-loaded liposomes improved adult female acne by decreasing lesion counts, sebum production, GAGS scores, and local androgen levels while increasing beclin-1 levels. ([Journal of Cosmetic Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28342238/))
- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))

## What reviewers say

Users consistently praise this ampoule for its deep, non-sticky hydration and lightweight texture that absorbs quickly, making it highly suitable for sensitive, dehydrated, and dry skin types. While the majority report a "plumping" effect and a gentle experience, a small minority mention mild tingling or frustration with the dropper packaging when the product runs low.

- Liked: Deep hydration (mostly mentioned)
- Liked: Lightweight texture (mostly mentioned)
- Liked: Gentle formula (often mentioned)
- Liked: Generous size (sometimes noted)
- Disliked: Packaging issues (sometimes noted)
- Disliked: Mild irritation (rarely noted)
- Disliked: Price concerns (rarely noted)
- Disliked: Scent concerns (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does MISSHA Super Aqua Ultra Hyalron Ampoule work for oily acne-prone skin?

This product is an average fit for oily acne-prone skin, providing moderate hydration and oil control with niacinamide and hyaluronic acid, though it lacks ingredients to target breakouts. To work best for this skin type, a product needs effective ingredients that target acne and hydration without clogging pores, plus lightweight humectants and skin-repairing ingredients that maintain balance.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

This serum fits your oily acne-prone skin thanks to niacinamide, which helps balance oil production, and multiple types of hyaluronic acid for deep hydration. It also includes calming botanical waters and flower extracts that are unlikely to irritate. To work best for this skin type, a product like this also needs ingredients that specifically target acne and breakouts without clogging pores.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### What does Hyaluronic Acid do for oily acne-prone skin?

Hyaluronic acid helps calm oily acne-prone skin by decreasing oil production and reducing breakouts while keeping the skin hydrated. It may also improve skin barrier function and help deliver acne-fighting treatments gently without causing irritation.
Sources: [Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35796638/), [The Journal of Investigative Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28163068/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in your evening routine, after cleansing and toning and before moisturizing, though some serums can also be used in the morning or twice a day. It is safe for your oily skin and helps keep it calm, but because it lacks ingredients to target blemishes and breakouts, this skin type also needs targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide.

### Can I use this serum with retinol, and in what order?

You can use this treatment alongside retinol to help keep your skin comfortable and hydrated while using stronger ingredients. Apply the treatment first to clean skin to provide deep moisture, and follow with your retinol once it is fully absorbed.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this serum?

You can use this serum in your evening routine, as treatments fit simply and safely there, though some can also be used in the morning or twice a day. Regular application helps keep oily skin hydrated and balanced, but because it lacks ingredients to target breakouts, this skin type also needs targeted acne-fighting ingredients like salicylic acid or benzoyl peroxide.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this serum clog pores, cause breakouts or purging for oily acne-prone skin?

This serum is unlikely to clog pores or cause purging for oily acne-prone skin, as it contains soothing ingredients and has a safe profile, though it lacks specific ingredients to target breakouts. To properly care for oily acne-prone skin, a product of this type needs acne-fighting and blemish-targeting ingredients to help clear pimples.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/)

### Can I use this serum around the eyes or on my body?

You can use this moisturizing treatment around your eyes and on your body, as its multiple forms of hyaluronic acid and soothing plant waters provide safe and deep hydration for delicate skin. However, oily acne-prone skin needs products that combine lightweight hydration with specific blemish-fighting ingredients to properly target breakouts.
Sources: [Aesthetic Plastic Surgery, 2026](https://pubmed.ncbi.nlm.nih.gov/40921777/)

### Is this serum fragrance-free and alcohol-free?

It has no drying alcohol and contains fragrance (limonene and linalool).

## Alternatives for oily acne-prone skin

- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-acne-prone-skin) — Superior fit — $22.25 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-acne-prone-skin) — High fit — $19.99 at Amazon
- [MEDI-PEEL Peptide 9 Volume White Cica All-in-one Essence](https://lovi.care/skincare/p/medi-peel/peptide-9-volume-white-cica-all-in-one-essence/for/oily-acne-prone-skin) — High fit — $24.40 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — $25.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Methylpropanediol, Glycerin, Cyclohexasiloxane, 1,2-Hexanediol, Niacinamide, Polyglycerin-3, Octyldodeceth-16, Ammonium Acryloyldimethyltaurate Vp Copolymer, Xanthan Gum, Ethylhexylglycerin, Pentylene Glycol, Adenosine, Methyl Diisopropyl Propionamide, Carbomer, Disodium Edta, Tromethamine, Cynara Scolymus Leaf Extract, Avena Sativa Kernel Extract Oat Kernel Extract, Sodium Hyaluronate, Polyquaternium-51, Camellia Sinensis Leaf Water, Hydrogenated Lecithin, Beta-Glucan, Citrus Aurantium Dulcis Peel Oil, Bergamot Oil Fruit, Lavandula Angustifolia Oil Lavender Oil, Anthemis Nobilis Oil Flower, Tocopherol, Hydroxypropyltrimonium Hyaluronate, Hydrolyzed Sodium Hyaluronate, Hydrolyzed Hyaluronic Acid, Sodium Acetylated Hyaluronate, Propanediol, Tetradecyl Aminobutyroylvalylaminobutyric Urea Trifluoroacetate, Sodium Hyaluronate Crosspolymer, Magnesium Chloride, Potassium Hyaluronate, Glycine Soja Seed Extract Soybean Seed Extract, Tetrahydropiperine, Phloretin, Arginine, Limonene, Linalool
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/missha/super-aqua-ultra-hyalron-ampoule/for/oily-acne-prone-skin