# MEDIPEEL PEPTIDE 9 VITANOL CREAM PRO for oily acne-prone skin

**Lovi Fit: Average fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: MEDIPEEL
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily acne-prone skin; other moisturizers fit it better.

## Why this fit

- Offers moderate hydration and soothing benefits for your oily skin, with ingredients like hyaluronic acids and ectoin providing general skin support. While niacinamide and salicylic acid help regulate oil and exfoliate, the formula is not specifically targeted to address your acne, blemishes, and breakouts.
- The blend of peptides and adenosine contributes to plumping and moisturizing effects, enhancing overall skin health.
- The product is safe for your skin, with no reported irritation risks due to the absence of harsh ingredients and the inclusion of soothing components.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin): Average (this page)

## Key ingredients

Niacinamide, Liposomal Vitamin Complex Vitanol, 9 Peptides

## What the research says

- Treatment with a combination of niacinamide and hyaluronic acid improved skin aging signs and demonstrated a senomorphic effect by decreasing SASP and autocrine signaling genes in women. ([Scientific Reports, 2024](https://pubmed.ncbi.nlm.nih.gov/39009698/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- A moisturizer containing licochalcone A, 1,2-decanediol, L-carnitine, and salicylic acid significantly reduced noninflammatory, inflammatory, and total acne lesion counts compared to a vehicle control in Thai patients during a 12-week maintenance phase. ([BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))

## Why other moisturizers fit oily acne-prone skin better

- Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components. ([Molecules, 2023](https://pubmed.ncbi.nlm.nih.gov/37446936/))
- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- A facial serum containing snail secretion filtrate, Calendula officinalis, and Glycyrrhiza glabra root extract significantly reduced inflammatory acne lesions compared to placebo in 66 participants with mild-to-moderate maskne over 12 weeks. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35763437/))

## What reviewers say

Users find this cream to be a rich, moisturizing solution that provides a healthy glow, particularly beneficial for dry skin and during winter. Many users report positive effects on skin brightness and firmness. However, individuals with oily skin often find the texture too heavy, and some users expected faster whitening results considering the price.

- Liked: Deep nourishment (often mentioned)
- Liked: Pleasant texture/scent (often mentioned)
- Liked: Anti-aging effects (sometimes noted)
- Liked: Brightening & glow (sometimes noted)
- Disliked: Too heavy/greasy (sometimes noted)
- Liked: Quality packaging (rarely noted)
- Disliked: High price (rarely noted)
- Disliked: Potential breakouts (rarely noted)
- Disliked: Slow whitening results (rarely noted)

## How to apply

- Use this AM and PM routine every day to help clear your skin. Always remember to finish with SPF in the morning.
- Apply the moisturizer after your cleanser and toner, right before your SPF during the day.
- Gently press a small amount into your skin and avoid rubbing to keep pores clear.
- Apply on clean, slightly damp skin to help the product absorb better and control oil.
- Avoid the sensitive eye area and do a simple patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does Medi-Peel Vitanol Cream Pro work for oily acne-prone skin?

This cream works moderately well for oily acne-prone skin, providing gentle hydration and calming care without clogging pores, though it is not specifically targeted to clear breakouts. Skincare products that fit this skin type better need powerful ingredients to treat acne and blemishes, combined with lightweight, oil-free hydrators to maintain a balanced complexion.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/)

### Which ingredients make this cream a good fit for oily acne-prone skin?

This cream contains niacinamide and salicylic acid to help regulate oil and exfoliate, along with hyaluronic acids and ectoin to provide moderate hydration and soothing benefits. To be a better fit for oily acne-prone skin, a product of this type needs powerful hydrating and repairing ingredients that directly target acne, blemishes, and breakouts without adding excess oil.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/)

### What does Niacinamide do for oily acne-prone skin?

Niacinamide helps balance oil production, calms redness, and is unlikely to irritate oily, acne-prone skin while improving blemishes. Clinical tests show it reduces excess oil and helps clear up both inflammatory and non-inflammatory acne breakouts.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38299457/)

### What does Liposomal Vitamin Complex do for oily acne-prone skin?

Liposomal Vitamin Complex helps balance oily skin and calm breakouts by delivering key nutrients deep into pores. It is unlikely to clog pores and may reduce redness, leaving your skin clear and smooth.

### Where does this cream go in a skincare routine for oily acne-prone skin?

This moisturizing treatment goes after your cleanser, hydrating toner, and treatment steps in the morning, or after your makeup remover, cleanser, cleansing toner, and treatment steps in the evening. It is unlikely to irritate your oily skin, but to properly care for acne-prone skin, this type of product also needs targeted blemish-fighting ingredients like salicylic acid or benzoyl peroxide.

### Can I use this cream with retinol, and in what order?

You can use this cream with retinol, and applying it before or after helps keep your skin soft and calm while you use your treatment. This type of product works best for oily acne-prone skin when it includes oil-regulating ingredients like salicylic acid and niacinamide, along with soothing elements to keep your barrier comfortable.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22648223/)

### How often should I use this cream?

You can use this moisturizing treatment twice daily as part of your morning and evening routines. Daily application helps maintain skin moisture and barrier function.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this cream clog pores, cause breakouts or purging for oily acne-prone skin?

This cream is unlikely to clog pores or cause breakouts on your oily acne-prone skin, as it has a safe profile with soothing ingredients and negligible complaints about pimples. However, because it is not specifically targeted to address acne and breakouts, this skin type ultimately needs a product with targeted blemish-clearing ingredients like salicylic acid and oil-controlling elements to keep pores clear.
Sources: [BioMed Research International, 2020](https://pubmed.ncbi.nlm.nih.gov/33150170/)

### Can I use this cream around the eyes or on my body?

You can use this moisturizing treatment around the eyes and on the body because it has a safe formula with no reported irritation risks. However, since the skin around the eyes and on certain body areas can be much thinner than facial skin, you should watch for any sensitivity when applying active ingredients like niacinamide and salicylic acid.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this cream fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [COSRX Advanced Snail 96 Mucin Power Essence](https://lovi.care/skincare/p/cosrx/advanced-snail-96-mucin-power-essence/for/oily-acne-prone-skin) — Superior fit — $15.88 at Amazon
- [Some By Mi Yuja Niacin Brightening Moisture Gel Cream](https://lovi.care/skincare/p/some-by-mi/yuja-niacin-brightening-moisture-gel-cream/for/oily-acne-prone-skin) — Superior fit — $15.50 at Amazon
- [Drunk Elephant Protini Polypeptide Cream](https://lovi.care/skincare/p/drunk-elephant/protini-polypeptide-cream/for/oily-acne-prone-skin) — High fit — $49.95 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- SPF: [make p:rem UV Defense Me Blue Ray Sun Cream](https://lovi.care/skincare/p/make-p-rem/uv-defense-me-blue-ray-sun-cream/for/oily-acne-prone-skin) — Superior fit — $25.99 at Amazon

## Where to buy

- Amazon.com: $32.56 (https://www.amazon.com/dp/B0CWRJ1FFR?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Niacinamide, Chinese Bellflower Root Extract, Liposomal Vitamin Complex Vitanol, 9 Peptides, Adenosine, Patented Redsnow Complex, Eosidin, Ectoin, Hyaluronic Acids Of Different Molecular Weights, Vitamin A, Collagen, Hippophae Rhamnoides Fruit Extract, Jojoba Seed Oil, Alpha-Bisabolol, Carbomer, Methylpropanediol, Hyaluronic Acid, Tromethamine, Hydrolyzed Hyaluronic Acid, Phaseolus Radiatus Seed Extract, Glycerin, Pentylene Glycol, Betaine, Pumpkin Seed Extract, Polygonum Fagopyrum Seed Extract, Punica Granatum Fruit Extract, Glucosylrutin, Hydrogenated Ethylhexyl Olivate, Disodium Edta, Palm Oil, Polyglutamic Acid, Belamcanda Chinensis Root Extract, Ethylhexylglycerin, Hydrogenated Lecithin, Hydrogenated Olive Oil, Caprylic Capric Triglyceride, Astaxanthin Extract, Lactobacillus Ferment, Salicylic Acid, Sucrose Palmitate, Citric Acid, Retinyl Palmitate, Tocopherol, Menadione, Polyglyceryl-4 Oleate, Glutathione, Artemisia Annua Extract, Linoleic Acid, Phaeodactylum Tricornutum Extract, Helianthus Annuus Seed Oil Sunflower Seed Oil, Arachis Hypogaea Oil, Camellia Japonica Flower Extract, Rosmarinus Officinalis Leaf Extract Rosemary Leaf Extract, Citrus Unshiu Peel Extract, Linolenic Acid, Coconut Oil, Alteromonas Extract Ferment, Phenethyl Alcohol, Polyglyceryl-10 Laurate, Olea Europaea Oil Fruit Olive Oil Fruit, Ascorbic Acid, Chlorella Minutissima Extract, Caprylyl Glycol, Sodium Phosphate, Lecithin, Retinal, Copper Tripeptide-1, Acetyl Hexapeptide-8, Oligopeptide-29, Palmitoyl Pentapeptide-4, Acetyl Octapeptide-3, Oligopeptide-32, Oligopeptide-6, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Tripeptide-5, Sh-Oligopeptide-1, Sh-Oligopeptide-2, Sh-Polypeptide-1, Sh-Polypeptide-10
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
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- Canada: https://lovi.care/skincare/ca/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medipeel/peptide-9-vitanol-cream-pro/for/oily-acne-prone-skin