# Mediheal N.M.F Aquaring Ampoule Mask EX for mature skin

**Lovi Fit: High fit for mature skin.**
Normal Skin Fit: High · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Mediheal](https://lovi.care/skincare/brands/mediheal)
Category: [Face masks](https://lovi.care/skincare/best/face-masks)

This fit is calculated for the concerns frequently associated with mature skin: fine lines, wrinkles, and loss of firmness. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for mature skin; a few nourishing masks fit it even better.

## Why this fit

- Offers excellent hydration for your normal skin due to sodium hyaluronate and polyglutamic acid, which hydrate and plump effectively.
- Hydrolyzed collagen and adenosine provide moderate benefits for wrinkles and fine lines by supporting skin elasticity.
- The formula is safe for your normal skin, with no risks of irritation due to the absence of harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/dry-skin): Superior
- [Combination skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin): High (this page)
- [Dry sensitive skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/oily-acne-prone-skin): Average

## Key ingredients

N.M.F, Sodium Hyaluronate, Aloe Barbadensis Leaf Juice, Hydrolyzed Collagen, Panthenol

## What the research says

- Topical hyaluronic acid filler serum combined with Botulinum toxin type A lengthened the duration of the toxin's effect in reducing wrinkles compared to Botulinum toxin type A alone. ([Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/))
- Adenosine-loaded dissolving microneedle patches showed similar or better efficacy on skin wrinkles, dermal density, elasticity, and hydration compared to adenosine cream in 22 female subjects. ([International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/))
- Horse oil-spread and adenosine-loaded dissolving microneedle patches significantly improved skin elasticity, hydration, dermal density, and wrinkles compared with adenosine-loaded dissolving microneedle patches in 20 women without causing adverse events. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Topical dexpanthenol acts as a moisturizer, improves stratum corneum hydration, accelerates wound healing and epidermal regeneration, reduces erythema, and improves symptoms of skin irritation compared to vehicle or no pretreatment. ([American Journal of Clinical Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12113650/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- A cream combining propolis, tea tree oil, and Aloe vera reduced erythema scars, acne severity index, and total lesion count better than erythromycin cream in sixty patients with mild to moderate acne vulgaris compared to placebo. ([Clinical Pharmacology, 2018](https://pubmed.ncbi.nlm.nih.gov/30588129/))
- Topical aloe vera gel significantly accelerated split-thickness skin graft donor-site healing compared to placebo in 12 patients, but showed no significant difference in pain relief. ([Plastic and Reconstructive Surgery, 2018](https://pubmed.ncbi.nlm.nih.gov/29649056/))
- Topical application of Aloe vera cream reduced postoperative pain at rest and during defecation, accelerated wound healing at two weeks, and decreased analgesic requirements in patients after open hemorrhoidectomy compared to placebo. ([Journal of Alternative and Complementary Medicine, 2010](https://pubmed.ncbi.nlm.nih.gov/20569031/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical dexpanthenol formulated in lipophilic vehicles improved stratum corneum hydration and reduced transepidermal water loss compared to vehicle control in humans. ([Arzneimittel-Forschung, 2000](https://pubmed.ncbi.nlm.nih.gov/10965426/))
- Hyaluronic acid, hyaluronic acid plus dexpanthenol, and isotonic saline nasal sprays all significantly improved dry nose symptoms over four weeks in 240 patients, with hyaluronic acid plus dexpanthenol providing superior nasal moisturisation compared to the other two. ([Auris, Nasus, Larynx, 2020](https://pubmed.ncbi.nlm.nih.gov/32067777/))

## What reviewers say

Based on a very large amount of data, this sheet mask is highly recommended for dry and dehydrated skin, providing an immediate glass skin effect. Users frequently praise the plush sheet and abundant hydrating essence. A moderate number of reviews mention a sticky finish, suggesting it is best for nighttime use.

- Liked: Intense hydration (mostly mentioned)
- Liked: Generous essence (often mentioned)
- Liked: Superior sheet fit (often mentioned)
- Liked: Soothing and calming (sometimes noted)
- Disliked: Sticky residue (sometimes noted)
- Disliked: Noticeable fragrance (rarely noted)
- Disliked: Temporary results (rarely noted)

## How to apply

- You can use this sheet mask in your PM routine about 2-3 times a week. Smooth it gently over your face and relax.
- Apply the sheet mask right after cleansing and toning, but before putting on your moisturizer.
- Place the sheet mask flat on your face and smooth it out gently with your fingers. Leave it on for ten to fifteen minutes before removing.
- Put the sheet mask on clean and dry skin for the best comfort. Gently pat any remaining essence into your skin after taking it off.
- Avoid getting the product into your eyes and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### What makes Mediheal N.M.F Aquaring Ampoule Mask EX a great fit for mature skin?

This mask is a great fit for mature skin because sodium hyaluronate and polyglutamic acid hydrate and plump the skin, while hydrolyzed collagen and adenosine support skin elasticity to help with fine lines. It is also completely safe for your skin, as the formula contains no harsh ingredients that might cause irritation.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### Which ingredients make this mask a good fit for mature skin?

This mask is a great fit for mature skin thanks to sodium hyaluronate and polyglutamic acid, which hydrate and plump dry areas. Additionally, hydrolyzed collagen and adenosine help support skin elasticity and reduce the look of fine lines and wrinkles.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### What do Natural Moisturizing Factors do for mature skin?

Natural moisturizing factors help keep mature skin feeling soft and smooth by holding onto water and supporting the outer skin barrier. Because aging skin can lose moisture easily, these components help maintain comfortable hydration and a healthy balance.
Sources: [Scientific Reports, 2025](https://pubmed.ncbi.nlm.nih.gov/41422283/), [Dermatologic Therapy, 2004](https://pubmed.ncbi.nlm.nih.gov/14728698/)

### What does Hyaluronic Acid do for mature skin?

Hyaluronic acid helps mature skin by deeply boosting moisture, improving elasticity, and smoothing the appearance of fine lines and wrinkles. Regular use keeps the skin looking plump and soft while supporting overall firmness and hydration.
Sources: [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/), [Skin Research and Technology, 2024](https://pubmed.ncbi.nlm.nih.gov/38591218/)

### Where does this mask go in a skincare routine for mature skin?

This nourishing mask goes into your weekly routine after cleansing and before your treatment and moisturizer. It is a great fit for mature skin, providing deep hydration and helping to smooth out fine lines safely.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Dermatologic Therapy, 2022](https://pubmed.ncbi.nlm.nih.gov/36200921/)

### Can I use this mask with retinol, and in what order?

You can use this mask alongside retinol by applying it during your weekly routine on a night when you skip retinol, as a nourishing mask helps keep mature skin soft and plump while avoiding irritation. Alternatively, you may apply it after a retinol treatment on the same night if your skin feels dry, helping to lock in moisture and support skin elasticity.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### How often should I use this mask?

You can use this nourishing mask once a week as part of your routine. It is a great fit for mature skin because it helps hydrate well and supports skin elasticity.
Sources: [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/), [Journal of Drugs in Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26151786/)

### Can this mask clog pores, cause breakouts or purging for mature skin?

This mask is a great fit for mature skin and is unlikely to clog pores or cause breakouts because the formula is safe and free of harsh, heavy ingredients. It helps keep skin feeling soft and smooth while providing deep hydration and gentle care for fine lines.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for mature skin

- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/p/mediheal/watermide-essential-mask/for/mature-skin) — Superior fit — $22.00 at Amazon
- [Numbuzin No.2 Water Collagen 65% Voluming Sheet Mask](https://lovi.care/skincare/p/numbuzin/no-2-water-collagen-65-voluming-sheet-mask/for/mature-skin) — High fit — $11.99 at Amazon
- [Dr. Jart+ Ceramidin Facial Barrier Mask](https://lovi.care/skincare/p/dr-jart/ceramidin-facial-barrier-mask/for/mature-skin) — High fit — $39.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/mature-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [COSRX Propolis Synergy Toner](https://lovi.care/skincare/p/cosrx/full-fit-propolis-synergy-toner/for/mature-skin) — Superior fit — $17.00 at Amazon
- Moisturizer: [Obagi Hydrate Luxe Moisture-Rich Cream](https://lovi.care/skincare/p/obagi/hydrate-luxe/for/mature-skin) — Superior fit — $85.00 at Amazon

## Where to buy

- Amazon.com: $21.90 (https://www.amazon.com/dp/B0DYDQS6RC?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 4 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycereth-26, Glycerin, Sodium Hyaluronate, 1,2-Hexanediol, Hydroxyethyl Urea, Rosa Centifolia Flower Water, Fomes Officinalis Extract Mushroom Extract, Witch Hazel Water, Prunus Amygdalus Dulcis Seed Extract, Glutamine, Glutamic Acid, Arginine, Alanine, Phenylalanine, Proline, Portulaca Oleracea Extract, Hydrolyzed Collagen, Aloe Barbadensis Leaf Juice, Beta-Glucan, Xanthan Gum, Betaine, Carbomer, Allantoin, Polysorbate 80, Adenosine, Disodium Edta, Tocopheryl Acetate, Polyglutamic Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- France: https://lovi.care/skincare/fr/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/n-m-f-aquaring-ampoule-mask-ex/for/mature-skin