# MEDIHEAL Collagen Ampoule Pad for dry skin

**Lovi Fit: High fit for dry skin.**
Dry Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/dry-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [MEDIHEAL](https://lovi.care/skincare/brands/mediheal)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with dry skin: flakiness, tightness, dehydration, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for dry skin; a few moisturizers fit it even better.

## Why this fit

- Offers moderate hydration for your dry skin due to the humectant action of Glycerin and Hydroxyethyl Urea, which help attract and retain moisture. Collagen extract also contributes to improving skin elasticity.
- The inclusion of Olea Europaea Fruit Oil and Ceramide NP provides some emollient and barrier-supporting benefits, though additional occlusive ingredients would enhance overall hydration for dry skin.
- The product is safe for your dry skin, as it contains soothing ingredients like Glycerin and Allantoin and lacks harsh or prohibited substances.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/dry-skin): High (this page)
- [Combination skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/oily-acne-prone-skin): High

## Key ingredients

Collagen Extract, Adenosine, Ceramide Np, Betaine, Lactobacillus Ferment

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- A lipid mixture enriched by ceramide NP with fatty acids of diverse chain lengths significantly improved skin barrier recovery rate, stratum corneum integrity, and hydration compared to a vehicle cream in healthy adult male volunteers with corticosteroid-impaired skin. ([Skin Pharmacology and Physiology, 2022](https://pubmed.ncbi.nlm.nih.gov/34348350/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical adenosine treatment significantly increased the anagen hair growth rate and thick hair rate compared to placebo in Japanese women with female pattern hair loss over 12 months. ([The Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/19239555/))
- Topical application of a disodium adenosine monophosphate-based formulation reduced wrinkles and hyperpigmentation while improving hydration, barrier function, skin lifting, and epidermal turnover in female participants. ([International Journal of Molecular Sciences, 2026](https://pubmed.ncbi.nlm.nih.gov/42278371/))
- Adenosine and cordycepin stimulate the Wnt/beta-catenin signaling pathway through adenosine receptor and PKA activation, promoting cell proliferation, migration, and growth factor secretion in cultured dermal fibroblasts. ([International Journal of Molecular Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/34070360/))
- Topical dry mouth products containing olive oil, betaine, and xylitol significantly increased unstimulated whole salivary flow rates, reduced xerostomia complaints, and improved quality of life in adults with polypharmacy-induced xerostomia compared to their normal routine care, with no clinically significant adverse events. ([Journal of Oral Rehabilitation, 2007](https://pubmed.ncbi.nlm.nih.gov/17824884/))
- Soaps containing betaine caused the least skin irritation compared to other tested soaps in twenty-eight healthy subjects, though irritation did not decrease with increasing concentrations of betaine. ([Skin Research and Technology, 2003](https://pubmed.ncbi.nlm.nih.gov/12535284/))
- A combination of Aloe barbadensis leaf extract and trimethylglycine in a 1:1 mass ratio synergistically increased aquaporin 3 expression by up to 380% in keratinocytes and safely improved skin hydration in healthy volunteers. ([Molecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38611819/))
- Probiotic-derived lotion successfully reduced inflammatory acne lesion counts and erythema index comparably to 2.5% benzoyl peroxide in patients with mild-to-moderate acne vulgaris, while causing fewer side effects. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35384257/))
- Topical application of Lactobacillus plantarum-GMNL6 enhanced collagen synthesis and SPTSSA gene expression while reducing melanin synthesis, Staphylococcus aureus biofilm, and Cutibacterium acnes proliferation, leading to clinical improvements in skin moisture, color, spots, wrinkles, UV spots, and porphyrins in human volunteers. ([International Journal of Medical Sciences, 2021](https://pubmed.ncbi.nlm.nih.gov/33526970/))
- Lactobacillus plantarum extracellular vesicles modulated extracellular matrix related gene expression in vitro and suppressed wrinkle formation and pigmentation in clinical trials. ([Current Issues in Molecular Biology, 2022](https://pubmed.ncbi.nlm.nih.gov/35723322/))

## What reviewers say

Based on a very large amount of data, users consistently praise these pads for their ability to deeply hydrate and plump the skin, often describing a "glass skin" effect that serves as an excellent base for makeup. They are highly effective for soothing redness and improving texture on sensitive skin. Some users note a sticky finish and a fragrance that may not suit everyone.

- Liked: Deep hydration & plumping (mostly mentioned)
- Liked: Generous essence (often mentioned)
- Liked: Versatile & convenient (often mentioned)
- Liked: High-quality pad (sometimes noted)
- Liked: Soothing & cooling (sometimes noted)
- Disliked: Noticeable fragrance (sometimes noted)
- Disliked: Lack of immediate glow (rarely noted)
- Disliked: Price and value (rarely noted)
- Disliked: Sticky residue (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using it 3 times a week and work your way up to daily use.
- Apply your moisturizer after your toner and before your sunscreen in the morning. At night, use it as the final step after your serum.
- Gently press a small amount of the moisturizer into your skin. Avoid rubbing to keep your dry skin happy.
- Apply the moisturizer on slightly damp skin to help lock in extra hydration. This is great for soothing dry and flaky areas .
- Avoid the sensitive eye area and do a patch test before your first use .
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### What makes MEDIHEAL Collagen Ampoule Pad a great fit for dry skin?

MEDIHEAL Collagen Ampoule Pad is a great fit because it offers moderate hydration for dry skin by using ingredients like glycerin and hydroxyethyl urea to attract and retain moisture, while collagen extract helps improve skin elasticity. It also includes olive oil and ceramide NP to support the skin barrier, alongside soothing ingredients like allantoin to keep the skin comfortable and safe.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this treatment a good fit for dry skin?

Glycerin and hydroxyethyl urea help attract and retain moisture for dry skin, while ceramide NP and olive oil support the skin barrier. Additionally, collagen extract helps improve skin elasticity.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Collagen Extract do for dry skin?

Collagen Extract helps keep dry skin hydrated and improves its elasticity. Studies show that using collagen regularly can boost skin moisture and make it feel much softer and smoother.
Sources: [Skin Pharmacology and Physiology, 2012](https://pubmed.ncbi.nlm.nih.gov/22270036/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### What does Adenosine do for dry skin?

Adenosine helps dry skin by boosting hydration and reducing dryness, roughness, and wrinkles. It modulates skin biological mechanisms to improve overall moisture and texture.
Sources: [International Journal of Cosmetic Science, 2018](https://pubmed.ncbi.nlm.nih.gov/29574973/), [Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30160014/)

### Where does this treatment go in a skincare routine for dry skin?

This treatment goes in your evening routine, after cleansing and before your moisturizer. Putting it in the evening keeps your routine simple and protects your skin while you sleep, though it is safe enough that some people also use it in the morning.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/)

### Can I use this treatment with retinol, and in what order?

You can use this treatment alongside retinol by applying the treatment first and following with your retinol after it absorbs. This helps keep your dry skin soft and comfortable while minimizing potential irritation.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/)

### How often should I use this treatment?

This treatment fits well into an evening routine for dry skin. Daily evening use is generally safe and helps keep dry skin feeling soft and smooth.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32141711/), [Health Science Reports, 2021](https://pubmed.ncbi.nlm.nih.gov/34141902/)

### Can this treatment clog pores, cause breakouts or purging for dry skin?

This treatment is unlikely to clog pores or cause breakouts for dry skin. It contains soothing ingredients like glycerin and allantoin and lacks harsh substances, making it safe for your skin type.

### Can I use this treatment around the eyes or on my body?

Yes, you can use this moisturizing treatment around the eyes and on the body because it has a safe profile and soothing ingredients like glycerin and allantoin. The skin around the eyes is very thin, so gentle hydrating treatments like this one are well-suited there, though richer barrier creams may be needed for very dry body areas.
Sources: [Surgical and Radiologic Anatomy, 2002](https://pubmed.ncbi.nlm.nih.gov/12375070/)

### Is this treatment fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for dry skin

- [Allies of Skin Peptides & Antioxidants Firming Daily Treatment](https://lovi.care/skincare/p/allies-of-skin/peptides-and-antioxidants-firming-daily-treatment/for/dry-skin) — High fit — $125.00 at Amazon
- [Medi-Peel Peptide 9 Volume Tox Cream](https://lovi.care/skincare/p/medi-peel/peptide-9-volume-tox-cream/for/dry-skin) — High fit — $21.55 at Amazon
- [StriVectin SD Advanced Plus Intensive Moisturizing Concentrate](https://lovi.care/skincare/p/strivectin/sd-advanced-plus-intensive-moisturizing-concentrate/for/dry-skin) — High fit — $149.00 at Amazon

## Pairs well with

- Cleanser: [La Roche-Posay Hydrating Gentle Cleanser](https://lovi.care/skincare/p/la-roche-posay/toleriane-hydrating-gentle-cleanser/for/dry-skin) — Superior fit — $19.99 at Amazon
- Hydrating Toner: [Pyunkang Yul Calming Deep Moisture Toner](https://lovi.care/skincare/p/pyunkang-yul/calming-deep-moisture-toner/for/dry-skin) — Superior fit — $16.99 at Amazon
- SPF: [d'Alba Piedmont Waterfull Mild Sunscreen](https://lovi.care/skincare/p/d-alba/piedmont-waterfull-mild-sunscreen/for/dry-skin) — Superior fit — $15.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Glycereth-26, 1,2-Hexanediol, Diphenyl Dimethicone, Triethylhexanoin, Betaine, Hydroxyacetophenone, Hydrogenated Lecithin, Polyglyceryl-10 Oleate, Hydroxyethyl Urea, Dipotassium Glycyrrhizate, Sodium Citrate, Allantoin, Octyldodeceth-16, Xanthan Gum, Hydroxyethylcellulose, Collagen Extract, Adenosine, Citric Acid, Disodium Edta, Olea Europaea Oil Fruit Olive Oil Fruit, Butylene Glycol, Pelargonium Graveolens Oil Flower, Lavandula Angustifolia Oil Lavender Oil, Anthemis Nobilis Oil Flower, Citrus Aurantium Dulcis Peel Oil, Juniperus Mexicana Oil, Mangifera Indica Fruit Extract, Lactobacillus Ferment, Ceramide Np, Extract Milk Protein, Caprylyl Glycol, Tripeptide-1, Acetyl Hexapeptide-8, Copper Tripeptide-1, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/collagen-ampoule-pad/for/dry-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/collagen-ampoule-pad/for/dry-skin
- France: https://lovi.care/skincare/fr/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/collagen-ampoule-pad/for/dry-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/collagen-ampoule-pad/for/dry-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/collagen-ampoule-pad/for/dry-skin