# Mediheal A:PE Protain Mask for dry sensitive skin

**Lovi Fit: Average fit for dry sensitive skin.**
Dry Skin Fit: Superior · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Mediheal](https://lovi.care/skincare/brands/mediheal)
Category: [Face masks](https://lovi.care/skincare/best/face-masks)

This fit is calculated for the concerns frequently associated with dry sensitive skin: flakiness, tightness, redness, fine lines, and wrinkles. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for dry sensitive skin; other nourishing masks fit it better.

## Why this fit

- Offers moderate benefits for your dry and sensitive skin, as squalane and glycerin provide emollient and humectant actions to hydrate and support the skin barrier. Milk protein and acetyl hexapeptide-8 further aid in skin repair and rejuvenation.
- Supportive ingredients like Centella Asiatica Extract and Glycerin offer additional hydration and soothing effects, addressing your dry or flaky skin concerns.
- The product is safe for your dry and sensitive skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/oily-skin): Average
- [Dry skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin): Average (this page)
- [Oily acne-prone skin](https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hydrolyzed Collagen, Sodium Hyaluronate, Centella Asiatica Extract, Squalane

## What the research says

- Argireline treatment twice daily for 4 weeks produced a significant anti-wrinkle effect with 48.9% total efficacy and decreased skin roughness in Chinese subjects compared with 0% efficacy and no decrease in roughness in the placebo group. ([American Journal of Clinical Dermatology, 2013](https://pubmed.ncbi.nlm.nih.gov/23417317/))
- Treatment with cross-linked hyaluronic acid-based microneedle patches combined with acetyl hexapeptide-8 or epidermal growth factor significantly improved wrinkles and skin hydration compared to the patch alone in Korean females over 29 days. ([Annals of Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/33911590/))
- Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements. ([Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing. ([Journal of Alternative and Complementary Medicine, 2020](https://pubmed.ncbi.nlm.nih.gov/32310680/))
- Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects. ([Journal of Cosmetic Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30945430/))
- Topical treatment with 5% vitamin C and 0.1% madecassoside significantly improved clinical scores for wrinkles, suppleness, firmness, roughness, and skin hydration, along with functional and structural remodeling of the elastic fiber network in 20 female volunteers with photoaged skin after 6 months compared to baseline. ([Experimental Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18503551/))
- Squalane at 0.005-0.015% counteracts UVA-induced oxidative stress, inflammation, and collagen metabolism inhibition while stimulating fibroblast migration in human dermal fibroblasts. ([Molecules, 2025](https://pubmed.ncbi.nlm.nih.gov/40363772/))
- Plant-derived squalane protected human dermal fibroblasts against UVA-induced damage by counteracting ROS formation, suppressing apoptosis-related proteins p53, caspase-3, caspase-9, and PARP, and restoring the pro-survival p-Akt/mTOR pathway. ([Antioxidants, 2025](https://pubmed.ncbi.nlm.nih.gov/40722956/))

## What reviewers say

Users with dry, sensitive, or compromised skin barriers report excellent outcomes, praising the mask for its rich, creamy essence that deeply moisturizes and calms redness. While highly effective for soothing irritation and flattening pimples, the heavy, milky texture can be too rich or sticky for those with oily or acne-prone skin.

- Liked: Rich hydration (mostly mentioned)
- Liked: Soothing and calming (mostly mentioned)
- Liked: Soft adherent sheet (often mentioned)
- Disliked: Heavy sticky finish (often mentioned)
- Liked: Barrier repair (sometimes noted)
- Disliked: Slow absorption (sometimes noted)
- Disliked: Artificial fragrance (rarely noted)
- Disliked: Fit issues (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine. Start using your sheet mask 3 times a week and increase to daily use if your dry skin tolerates it.
- Apply the sheet mask right after cleansing and toning, but always before your rich moisturizer .
- Unfold the sheet mask gently and smooth it evenly over your face, avoiding any harsh pulling or rubbing.
- Place the sheet mask onto clean, slightly damp skin to help lock in extra moisture for flaky areas.
- Avoid the sensitive eye area and do a quick patch test before your very first use.
- Video: https://storage.pora.ai/cf9cbc1593b43309df7ca9cfe4fbbdae.mp4

## Questions and answers

### How well does Mediheal A:PE Protain Mask work for dry sensitive skin?

The Mediheal A:PE Protain Mask is an average fit for dry sensitive skin, offering moderate hydration and barrier support through ingredients like squalane, glycerin, and Centella asiatica extract. It is unlikely to cause irritation, but a product for this skin needs rich hydrating ingredients like collagen and sodium hyaluronate along with a strong focus on calming components to ensure optimal moisture and soothe sensitivity.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this mask a good fit for dry sensitive skin?

Squalane and glycerin help hydrate and support your skin barrier, while Centella Asiatica extract and milk protein soothe and repair dry and sensitive areas. To work best for this skin type, a nourishing mask needs rich hydrating and calming ingredients like collagen and hyaluronic acid to maintain moisture without causing irritation.
Sources: [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for dry sensitive skin?

Niacinamide helps dry sensitive skin by calming irritation and keeping moisture locked in so your face feels soft and smooth. It works to build up your skin barrier and calm redness while being very gentle and unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/), [International Journal of Pharmaceutics, 2013](https://pubmed.ncbi.nlm.nih.gov/23220080/)

### What does Hydrolyzed Collagen do for dry sensitive skin?

Hydrolyzed collagen helps make dry skin feel much more smooth and hydrated while helping to calm sensitive areas. Regular use over a few weeks significantly improves moisture levels and helps keep the skin barrier strong and comfortable.
Sources: [Cureus, 2023](https://pubmed.ncbi.nlm.nih.gov/38192916/), [International Journal of Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33742704/)

### Where does this mask go in a skincare routine for dry sensitive skin?

This nourishing mask goes in your weekly routine, where Lovi places it after cleansing and before treatments and moisturizing. A product of this type for dry and sensitive skin needs ingredients like squalane, glycerin, Centella asiatica extract, and milk protein to hydrate, soothe, and support the skin barrier.
Sources: [The Journal of Dermatological Treatment, 2022](https://pubmed.ncbi.nlm.nih.gov/32239984/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Can I use it with retinol, and in what order?

You can use this mask with retinol by applying the mask after cleansing and before your retinol treatment on your weekly mask days, or on alternating nights to keep your dry and sensitive skin calm. This product is unlikely to cause irritation, but dry and sensitive skin works best with products that offer deep barrier repair and rich nourishing ingredients.
Sources: [Cutis, 2006](https://pubmed.ncbi.nlm.nih.gov/17121065/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### How often should I use this mask?

You can use this nourishing mask once a week as part of your weekly routine for dry sensitive skin. A product of this type works best for this skin when it includes hydrating and barrier-supporting ingredients like squalane, glycerin, and soothing plant extracts.

### Can it clog pores, cause breakouts or purging for dry sensitive skin?

This mask is unlikely to clog pores or cause breakouts for dry sensitive skin, as it has a safe profile with no harsh ingredients. However, because it has a heavy, sticky finish, a product of this type needs lightweight hydrators and soothing plant extracts like squalane, glycerin, and Centella Asiatica extract to keep dry skin comfortable without feeling weighed down.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Indian Journal of Pharmaceutical Sciences, 2016](https://pubmed.ncbi.nlm.nih.gov/27168678/)

### Is this mask fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol. Cetearyl alcohol is a fatty alcohol, which soften the skin.

## Alternatives for dry sensitive skin

- [Numbuzin No.2 Water Collagen 65% Voluming Sheet Mask](https://lovi.care/skincare/p/numbuzin/no-2-water-collagen-65-voluming-sheet-mask/for/dry-sensitive-skin) — Superior fit — $11.99 at Amazon
- [Mediheal Watermide Essential Mask](https://lovi.care/skincare/p/mediheal/watermide-essential-mask/for/dry-sensitive-skin) — High fit — $22.00 at Amazon
- [Biologique Recherche Masque Visolastine+](https://lovi.care/skincare/p/biologique-recherche/masque-visolastine/for/dry-sensitive-skin) — High fit — $230.00 at Amazon

## Pairs well with

- Cleanser: [CeraVe Hydrating Cleanser](https://lovi.care/skincare/p/cerave/hydrating-facial-cleanser/for/dry-sensitive-skin) — Superior fit — $16.97 at Amazon
- Soothing Toner: [Clarins Toning Lotion with Camomile](https://lovi.care/skincare/p/clarins/soothing-toning-lotion/for/dry-sensitive-skin) — Superior fit — $28.05 at Amazon
- Moisturizer with Sun Protection: [d'Alba UVessence Mild Waterfull Sun Cream SPF 50](https://lovi.care/skincare/p/d-alba/uvessence-mild-waterfull-sun-cream-spf-50/for/dry-sensitive-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Dipropylene Glycol, Niacinamide, Propylene Glycol, Cetearyl Alcohol, Squalane, Glycerin, Hydrogenated Lecithin, C12-16 Alcohols, Palmitic Acid, Dipotassium Glycyrrhizate, Lactobacillus Eriodictyon Californicum Extract Ferment, Lactobacillus Soybean Extract Ferment, Centella Asiatica Extract, Origanum Vulgare Leaf Extract, Cinnamomum Cassia Bark Extract, Vitex Agnus Castus Extract, Chamomilla Recutita Extract Matricaria Extract, Chamaecyparis Obtusa Leaf Extract, Peg-12 Dimethicone, Hydroxyethyl Urea, Willow Bark Extract, Scutellaria Baicalensis Root Extract, Betaine, Bifida Ferment Filtrate, Pentylene Glycol, Xylitylglucoside, Adenosine, Anhydroxylitol, Leontopodium Alpinum Callus Culture Extract, Xylitol, Dimethicone, Extract Milk Protein, Tocopheryl Acetate, Hydrolyzed Collagen, Sodium Hyaluronate, Glucose, Portulaca Oleracea Extract, Butylene Glycol, Glycine, Serine, Glutamic Acid, Aspartic Acid, Leucine, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Valine, Threonine, Proline, Isoleucine, Histidine, Methionine, Cysteine, Acetyl Hexapeptide-8, Phenoxyethanol, Copper Tripeptide-1, Ethylhexylglycerin, Disodium Edta, Carbomer, 1,2-Hexanediol, Zanthoxylum Piperitum Fruit Extract, Usnea Barbata Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Ireland: https://lovi.care/skincare/ie/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Germany: https://lovi.care/skincare/de/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- France: https://lovi.care/skincare/fr/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Italy: https://lovi.care/skincare/it/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Netherlands: https://lovi.care/skincare/nl/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Spain: https://lovi.care/skincare/es/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Canada: https://lovi.care/skincare/ca/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Australia: https://lovi.care/skincare/au/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Singapore: https://lovi.care/skincare/sg/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/mediheal/a-pe-protain-mask/for/dry-sensitive-skin