# Medicube PDRN Pink Peptide Serum for oily skin

**Lovi Fit: Average fit for oily skin.**
Oily Skin Fit: Average · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/oily-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Medicube](https://lovi.care/skincare/brands/medicube)
Category: [Moisturizers and moisturizing serums](https://lovi.care/skincare/best/moisturizers)

This fit is calculated for the concerns frequently associated with oily skin: shine, enlarged pores, blackheads, and blemishes. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

Works for oily skin; other moisturizers fit it better.

## Why this fit

- Offers moderate suitability for your oily skin as niacinamide helps regulate sebum production, while hyaluronic acid and salmon egg extract provide essential hydration and plumping benefits. This combination addresses general skincare needs without specifically targeting the primary concern of oily shine.
- While the formula is safe for your oily skin and free from harsh ingredients, it lacks sufficient targeted components for optimal oil control, providing only supportive benefits for your main goal.
- The product is safe for your skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/oily-skin): Average (this page)
- [Dry skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/combination-skin): Average
- [Sensitive skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/acne-prone-skin): Average
- [Skin with dark spots](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/oily-acne-prone-skin): Average

## Key ingredients

Niacinamide, Hydrolyzed Collagen, Sodium Dna

## What the research says

- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of TAC/Collagen postbiotics gel improved skin moisture score and inflammation index, and reduced porphyrins and brown spots in 20 volunteers with acne vulgaris. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/35818134/))
- Topical collagen tripeptide application improved skin wrinkles, elasticity, and density while reducing advanced glycated end products in 22 Asian women over 4 weeks. ([International Journal of Molecular Sciences, 2022](https://pubmed.ncbi.nlm.nih.gov/35163025/))
- Marine collagen extracted from Greenland halibut skin showed a non-cytotoxic effect on fibroblast cells and provided a slight skin hydration effect when incorporated into cosmetic hydrogel formulations at dosages of 0.1, 0.25, and 0.5% in 23 healthy volunteers. ([Marine Drugs, 2023](https://pubmed.ncbi.nlm.nih.gov/36827098/))
- Topical application of Low-Peony PDRN enhanced barrier recovery and improved periorbital skin elasticity in human subjects. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/41516097/))
- Polydeoxyribonucleotide promotes skin regeneration by increasing ERK phosphorylation, collagen accumulation, and cell proliferation and migration in fibroblasts while inhibiting ERK phosphorylation and inflammatory cytokine expression in keratinocytes. ([Molecular Medicine Reports, 2023](https://pubmed.ncbi.nlm.nih.gov/37350391/))
- A topical mixture of polydeoxyribonucleotide, vitamin C, and niacinamide delivered via a microneedling therapy system decreased skin pigmentation and increased skin elasticity by attenuating melanogenesis and the destruction of collagen and elastin fibers in a UV-B-radiated animal model. ([Molecules, 2022](https://pubmed.ncbi.nlm.nih.gov/35209068/))

## Why other moisturizers fit oily skin better

- A panthenol-enriched mask improved skin hydration, regulated sebum, and reduced redness and TEWL across dry sensitive, oily sensitive, and oily acne skin subgroups with excellent tolerance and no adverse reactions. ([Journal of Cosmetic Dermatology, 2024](https://pubmed.ncbi.nlm.nih.gov/38366684/))
- Gluconolactone chemical peels lower skin pH and transepidermal water loss while demonstrating seboregulatory properties in 16 female subjects. ([Journal of Cosmetic Dermatology, 2023](https://pubmed.ncbi.nlm.nih.gov/37335807/))
- Combining 10% gluconolactone chemical peeling with oxybrasion or microneedle mesotherapy increased skin hydration and decreased sebum, pH, and TEWL in twenty-one Caucasian women, with no significant differences between the two methods. ([Skin Research and Technology, 2023](https://pubmed.ncbi.nlm.nih.gov/37357656/))

## What reviewers say

Based on a very large amount of data, this serum is highly praised for delivering intense hydration and a radiant "glass skin" glow, with users frequently reporting immediate improvements in skin plumpness and elasticity. The viscous texture is often noted for its barrier-repairing qualities. A polarizing feature is the distinct scent, described as floral and fishy, which some users find unpleasant.

- Liked: Deep hydration (mostly mentioned)
- Liked: Radiant glow (often mentioned)
- Liked: Smoother texture (often mentioned)
- Liked: Soothing and gentle (sometimes noted)
- Disliked: Unpleasant scent (sometimes noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Small quantity (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Could be used as part of your AM or PM routine every day to keep your face fresh.
- Apply this moisturizer after cleansing and toning, but right before your SPF in the morning.
- Gently press a small amount into your skin and let it absorb fully.
- Apply on clean, slightly dry skin to help control that oily shine.
- Avoid the eye area and do a quick patch test before your first use.
- Video: https://storage.pora.ai/2f72f5d69f07beeafc30237f829efbff.mp4

## Questions and answers

### How well does medicube PDRN Pink Peptide Serum work for oily skin?

This serum works moderately for oily skin as it provides hydration and helps regulate oil, but it does not fully target shiny skin. Oily skin needs a product that offers lightweight hydration, niacinamide to control oil and minimize pores, and soothing ingredients without clogging pores.
Sources: [International Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23738607/)

### Which ingredients make this serum a good fit for oily skin?

Niacinamide helps regulate oil production, while hyaluronic acid and salmon egg extract provide essential hydration without making your skin greasy. Oily skin needs a product that balances oil and provides lightweight moisture without clogging pores.
Sources: [International Journal of Cosmetic Science, 2013](https://pubmed.ncbi.nlm.nih.gov/23738607/)

### What does Niacinamide do for oily skin?

Niacinamide helps balance oily skin by significantly reducing excess oil production and shine. It is well tolerated and may improve skin texture without clogging pores.
Sources: [Journal of Cosmetic and Laser Therapy, 2006](https://pubmed.ncbi.nlm.nih.gov/16766489/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Hydrolyzed Collagen do for oily skin?

Hydrolyzed collagen helps keep oily skin hydrated and balanced without feeling heavy or greasy. Because this type of skin tends to lose moisture while producing excess oil, it needs lightweight ingredients that provide hydration and support overall skin health.
Sources: [Journal of Cosmetic Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26362110/), [Journal of Drugs in Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/30681787/)

### Where does this serum go in a skincare routine for oily skin?

This treatment goes in the evening routine after cleansing and toning, and before moisturizing. It is safe for oily skin, but to better manage shine, an oily skin routine needs ingredients that specifically target excess oil control.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the serum first to give your skin hydration, followed by retinol once it absorbs. This routine is unlikely to cause irritation since the formula is gentle and free from harsh ingredients, though oily skin needs oil-controlling ingredients like niacinamide or salicylic acid for the best shine control.

### How often should I use this serum?

You can use this treatment serum in your evening routine for simplicity and extra safety around sun exposure. To care for oily skin, this type of product needs targeted oil-control ingredients.

### Can this serum clog pores, cause breakouts or purging for oily skin?

This serum is unlikely to cause breakouts or clog pores on oily skin because it has a safe formula free from harsh ingredients, though a few reviewers have rarely experienced breakouts. A product of this type needs stronger oil-controlling ingredients to properly manage oily shine.

### Can I use this serum around the eyes or on my body?

This serum is safe to use around the eyes and on the body because its formula is gentle and free from harsh ingredients. However, a product for oily skin needs targeted oil-control ingredients to properly manage shine in those areas.

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily skin

- [Elizavecca Witch Piggy Hell Pore Control Hyaluronic Acid 97%](https://lovi.care/skincare/p/elizavecca/witch-piggy-hell-pore-control-hyaluronic-acid-97/for/oily-skin) — High fit — $8.40 at Amazon
- [Torriden DIVE-IN Low Molecular Hyaluronic Acid Serum](https://lovi.care/skincare/p/torriden/dive-in-low-molecular-hyaluronic-acid-serum/for/oily-skin) — High fit — $22.25 at Amazon
- [COSRX Hydrium Triple Hyaluronic Moisture Ampoule](https://lovi.care/skincare/p/cosrx/hydrium-triple-hyaluronic-moisture-ampoule/for/oily-skin) — High fit — $19.99 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [SOME BY MI Snail Truecica Miracle Repair Toner](https://lovi.care/skincare/p/some-by-mi/snail-truecica-miracle-repair-toner/for/oily-skin) — Superior fit — $15.60 at Amazon
- SPF: [CeraVe AM Facial Moisturizing Lotion](https://lovi.care/skincare/p/cerave/am-facial-moisturizing-lotion-spf-30/for/oily-skin) — Superior fit — $14.97 at Amazon

## Where to buy

- Amazon.com: $18.90 (https://www.amazon.com/dp/B0DBF65JYY?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 6 Nov 2026.

## Ingredients

Water, Disodium Edta, Niacinamide, Hydrolyzed Collagen, Sodium Dna, Milt Extract, Copper Tripeptide-1, Acetyl Hexapeptide-8, Palmitoyl Pentapeptide-4, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Butylene Glycol, 1,2-Hexanediol, Glycerin, Dipropylene Glycol, Polyglycerin-3, Glyceryl Acrylate Acrylic Acid Copolymer, Pvm Ma Copolymer, Hyaluronic Acid, Ethylhexylglycerin, Glycereth-26, Adenosine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Isopropyl Myristate, Ubiquinone, Caprylyl Glycol, Tromethamine, Sodium Acrylate Sodium Acryloyldimethyl Taurate Copolymer, Polyisobutene, Caprylyl Capryl Glucoside, Sorbitan Oleate, Atelocollagen, Salmon Egg Extract
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/medicube/pdrn-pink-peptide-serum/for/oily-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Ireland: https://lovi.care/skincare/ie/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Germany: https://lovi.care/skincare/de/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- France: https://lovi.care/skincare/fr/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Italy: https://lovi.care/skincare/it/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Netherlands: https://lovi.care/skincare/nl/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Spain: https://lovi.care/skincare/es/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Canada: https://lovi.care/skincare/ca/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Australia: https://lovi.care/skincare/au/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Singapore: https://lovi.care/skincare/sg/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/medicube/pdrn-pink-peptide-serum/for/oily-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/medicube/pdrn-pink-peptide-serum/for/oily-skin