# Kiehl's Ultra Pure High-Potency Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: Superior · Effectiveness: High · Safety: High.

Page: https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [Kiehl's](https://lovi.care/skincare/brands/kiehl-s)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Excellent suitability for your combination skin is provided by glycerin and hyaluronic acid, which offer optimal hydration without exacerbating oiliness.
- The serum's moderate concentrations of these humectants effectively address your oily shine by providing balanced moisturization.
- The product is safe for your skin, as it contains no prohibited or harsh ingredients and carries no risk of irritation.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/sensitive-skin): Average
- [Acne-prone skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/oily-acne-prone-skin): High

## Key ingredients

Niacinamide, Hyaluronic Acid, Glycerin

## What the research says

- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Topical treatment of nicotinamide, alone or in combination with other active ingredients, reduces the progression of skin aging and hyperpigmentation in clinical trials while being well tolerated. ([Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/))
- Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin. ([Journal of Cosmetic Dermatology, 2021](https://pubmed.ncbi.nlm.nih.gov/33103316/))
- Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women. ([The Journal of Investigative Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/17882270/))
- Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging. ([Dermatologic Surgery, 2005](https://pubmed.ncbi.nlm.nih.gov/16029679/))
- Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control. ([Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/))
- Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction. ([Clinical Oral Investigations, 2022](https://pubmed.ncbi.nlm.nih.gov/34623507/))
- Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days. ([BMC Oral Health, 2019](https://pubmed.ncbi.nlm.nih.gov/31311529/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))

## What reviewers say

Based on a very large amount of data, this collection of minimalist serums is widely praised for its fast-absorbing, non-sticky textures and efficacy in targeting specific skin concerns like dryness, excess oil, and uneven texture. The Hyaluronic Acid version is lauded for immediate plumping, the Niacinamide serum is a favorite for controlling shine without irritation, and the Glycolic Acid variant is effective for smoothing skin, though it requires caution for sensitive types.

- Liked: Fast-absorbing texture (mostly mentioned)
- Liked: Effective oil control (often mentioned)
- Liked: Gentle minimalist formula (often mentioned)
- Liked: Immediate hydration (often mentioned)
- Disliked: High price point (often mentioned)
- Liked: Visible skin smoothing (sometimes noted)
- Disliked: Lack of dramatic results (sometimes noted)
- Disliked: Packaging concerns (rarely noted)
- Disliked: Potential irritation (rarely noted)
- Disliked: Texture preference (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes Kiehl's Ultra Pure High-Potency Serum a great fit for combination skin?

Kiehl's Ultra Pure High-Potency Serum is a great fit for your combination skin because glycerin and hyaluronic acid provide balanced moisture without making your face oily. This targeted hydration helps control shiny spots while keeping your skin feeling soft and comfortable.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Which ingredients make this serum a good fit for combination skin?

Glycerin and hyaluronic acid make this serum a great fit for combination skin because they provide balanced moisture without making your skin feel oily. This helps keep dry areas soft while controlling shiny spots.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### What does Niacinamide do for combination skin?

Niacinamide helps balance oily areas by reducing excess shine and pore size while keeping dry patches hydrated and smooth. It also works to calm redness and even out skin tone, making it very suitable for combination skin.
Sources: [The British Journal of Dermatology, 2002](https://pubmed.ncbi.nlm.nih.gov/12100180/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### What does Hyaluronic Acid do for combination skin?

Hyaluronic acid is a great fit for combination skin because it quenches dry areas with a boost of hydration while keeping oily zones balanced. Regular use helps smooth out fine lines and makes your skin feel soft and plump without causing irritation.
Sources: [Dermatology and Therapy, 2021](https://pubmed.ncbi.nlm.nih.gov/34176098/), [Journal of Drugs in Dermatology, 2011](https://pubmed.ncbi.nlm.nih.gov/22052267/)

### Where does this serum go in a skincare routine for combination skin?

This treatment serum goes in your evening routine after cleansing and toning, and before moisturizing. Putting treatments in the evening keeps the routine simple and adds extra safety around sun exposure.

### Can I use this serum with retinol, and in what order?

You can use this serum with retinol by applying the treatment after cleansing and before your moisturizer, ideally in your PM routine. Glycerin and hyaluronic acid help provide balanced moisturization for your skin without adding extra oil.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### How often should I use this serum?

This serum is a great fit for your combination skin, and you can safely use it in the evening as part of your routine. Glycerin and hyaluronic acid provide balanced moisturization without making your oily shine worse.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/), [Antioxidants, 2021](https://pubmed.ncbi.nlm.nih.gov/34439563/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

This serum is unlikely to clog pores or cause breakouts on combination skin. It features lightweight moisture-boosting ingredients that hydrate dry areas without making oily spots heavier or causing irritation.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

No store in United States has a checked price for this product, so the page shows none.

## Ingredients

Water, Glycerin, Hyaluronic Acid, Phenoxyethanol, Chlorphenesin, Tetrasodium Glutamate Diacetate, Citric Acid
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/kiehl-s/ultra-pure-high-potency-serum/for/combination-skin