# IT'S SKIN Power 10 Formula VC Effector for oily acne-prone skin

**Lovi Fit: High fit for oily acne-prone skin.**
Oily Skin Fit: High · Effectiveness: Average · Safety: Excellent.

Page: https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: IT'S SKIN
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with oily acne-prone skin: shine, breakouts, blemishes, and enlarged pores. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for oily acne-prone skin; a few serums fit it even better.

## Why this fit

- Offers moderate brightening and evening of skin tone for your oily skin, as Ascorbyl Tetraisopalmitate and Camellia Sinensis Leaf Extract provide antioxidant and anti-inflammatory effects that also help with seboregulation.
- While the formula is generally hydrating and soothing, its primary benefits are supportive rather than directly targeting your acne, blemishes, and breakouts.
- The product is safe for your oily skin, with no risks of irritation due to the absence of harsh ingredients and the inclusion of soothing Camellia Sinensis Leaf Extract.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/dry-skin): High
- [Combination skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/combination-skin): High
- [Sensitive skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/dark-spots): High
- [Mature skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/dry-sensitive-skin): High
- [Oily acne-prone skin](https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin): High (this page)

## Key ingredients

Ascorbic Acid Ascorbyl Tetraisopalmitate, Glycerin, Polyglutamic Acid, Camellia Sinensis Leaf Extract, Butylene Glycol

## What the research says

- Topical formulations containing ascorbyl tetraisopalmitate, coenzyme Q10, green tea polyphenols, and resveratrol reduced the release of inflammatory cytokines and attenuated inflammatory signs compared to untreated skin and vehicle in 25 Japanese volunteers exposed to sodium dodecyl sulfate. ([European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/))
- An anti-acne hydrogel containing Aloe barbadensis, Garcinia mangostana, and Camellia sinensis extracts showed superior antiacne and antiblotch activities compared to 1% clindamycin gel in sixty subjects with mild-moderate acne. ([Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/))
- A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women. ([Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/))
- Poly-gamma-glutamic acid derived from a novel Bacillus subtilis strain dose-dependently increased skin barrier markers, hyaluronic acid synthesis, and aquaporin 3 expression in keratinocytes, and elevated filaggrin, involucrin, CD44, and aquaporin 3 expression in a reconstructed skin model compared to the control. ([International Journal of Molecular Sciences, 2025](https://pubmed.ncbi.nlm.nih.gov/39940752/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- The emollient V0034CR significantly reduced TEWL compared to vehicle and vehicle plus glycerol, and significantly increased corneometry scores compared to vehicle and vehicle plus petrolatum in healthy volunteers with dry skin, demonstrating combined barrier function improvement from petrolatum and hydration improvement from glycerol. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31532576/))
- Ten days of treatment with a cream containing 20% glycerin significantly increased skin hydration measured by corneometer values in 17 healthy volunteers compared to a placebo cream, but showed no influence on transepidermal water loss or skin sensitivity to an irritating surfactant. ([International Journal of Cosmetic Science, 2001](https://pubmed.ncbi.nlm.nih.gov/18498456/))
- Niacinamide/glycerin body moisturizers provided better rapid and prolonged improvement of cosmetic xerosis through functional improvement of stratum corneum barrier function compared to no treatment and conventional moisturizers in female subjects. ([Journal of Drugs in Dermatology, 2012](https://pubmed.ncbi.nlm.nih.gov/22206073/))
- Curcumin-loaded polyglutamic acid and gum arabic electrospun nanofibers accelerated wound healing, increased TGF-beta1 and VEGF expression, reduced inflammatory factors, and enhanced re-epithelialization and tissue regeneration in a mouse model with acute full-thickness skin defects. ([International Journal of Biological Macromolecules, 2024](https://pubmed.ncbi.nlm.nih.gov/38554903/))
- Polyglutamic acid and polylysine composite hydrogels promote wound repair and hemostasis through high water absorption, bioadhesion, calcium ion-mediated coagulation factor activation, and inherent antibacterial properties in a deep skin defect model. ([Macromolecular Bioscience, 2021](https://pubmed.ncbi.nlm.nih.gov/33656254/))
- Topical green tea extract significantly improved clinical symptoms, tear breakup times, and meibomian gland health compared to standard treatment in patients with dry eye and Meibomian Gland Dysfunction. ([Journal of Clinical and Diagnostic Research, 2017](https://pubmed.ncbi.nlm.nih.gov/28384900/))
- Topical low-dose green tea extract reduces UVB-induced p53 expression and apoptosis in human skin keratinocytes compared to placebo. ([Experimental Dermatology, 2009](https://pubmed.ncbi.nlm.nih.gov/18631247/))
- Topical application of green tea extract encapsulated chitosan microparticles improved skin elasticity, melanin index, and facial wrinkles compared to a placebo in female volunteers without causing skin irritation. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34965006/))

## What reviewers say

Based on a very large amount of data, this Vitamin C serum is frequently praised for its brightening effects and hydrating properties, making it a popular choice for those with dry or dull skin. It is also noted for being gentle and suitable for sensitive or beginner users. Some users experience a sticky finish or find the results take a considerable amount of time to become apparent, and a few report issues with the packaging or breakouts. The potency is considered mild by some, not ideal for those seeking significant anti-aging benefits.

- Liked: Brightens complexion (often mentioned)
- Liked: Hydrating formula (often mentioned)
- Liked: Gentle on skin (sometimes noted)
- Liked: Pleasant texture (sometimes noted)
- Disliked: Slow results (sometimes noted)
- Liked: Citrus scent (rarely noted)
- Disliked: Caused breakouts (rarely noted)
- Disliked: Low potency (rarely noted)
- Disliked: Packaging design (rarely noted)
- Disliked: Sticky finish (rarely noted)

## How to apply

- Could be used as part of your PM routine. Start 3 times a week and build up to daily use if your skin tolerates it well.
- Apply your serum after cleansing and toning, but before putting on your moisturizer.
- Gently press 2 to 3 drops of the serum into your skin and let it absorb for a minute.
- Apply the serum on clean, dry skin to help manage your blemishes safely.
- Do a patch test before your first use and avoid the delicate eye area.
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes IT'S SKIN VC Effector a great fit for oily acne-prone skin?

IT'S SKIN Power 10 Formula VC Effector is a great fit because it helps brighten your skin tone and keeps extra oil under control while staying gentle on your face. The vitamin C and green tea extract in the formula calm inflammation and are very unlikely to irritate your skin.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/)

### Which ingredients make this serum a good fit for oily acne-prone skin?

Ascorbyl Tetraisopalmitate and Camellia Sinensis Leaf Extract make this serum a great fit for your oily acne-prone skin because they provide antioxidant and anti-inflammatory effects that help control oil and even out skin tone. The formula also includes Glycerin and Polyglutamic Acid to keep your skin hydrated and smooth without causing irritation.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/)

### What does Ascorbic Acid do for oily acne-prone skin?

Ascorbic acid helps brighten dark spots and calms redness for oily, acne-prone skin while providing antioxidant protection. It is unlikely to clog pores, but this skin type also needs soothing and oil-balancing ingredients like niacinamide to keep breakouts under control.
Sources: [Journal of the American Academy of Dermatology, 2025](https://pubmed.ncbi.nlm.nih.gov/40233838/), [Journal of Cosmetic Dermatology, 2004](https://pubmed.ncbi.nlm.nih.gov/17147561/)

### What does Glycerin do for oily acne-prone skin?

Glycerin helps keep oily acne-prone skin hydrated without feeling heavy. It draws moisture into the skin while supporting the skin barrier so it stays soft and balanced.
Sources: [The British Journal of Dermatology, 2008](https://pubmed.ncbi.nlm.nih.gov/18510666/), [Clinical, Cosmetic and Investigational Dermatology, 2017](https://pubmed.ncbi.nlm.nih.gov/28860834/)

### Where does this serum go in a skincare routine for oily acne-prone skin?

This treatment goes in your evening routine, applied after cleansing and before your moisturizer for simplicity and extra safety around sun exposure. It is safe for oily skin and unlikely to cause irritation.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying your retinol product first and following with this treatment to help brighten and calm your skin.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/)

### How often should I use this serum?

This treatment is used in the evening for your oily acne-prone skin, following your cleanser and cleansing toner. It helps brighten your skin tone and soothe irritation with a low risk of side effects.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/)

### Can it clog pores, cause breakouts or purging for oily acne-prone skin?

IT'S SKIN Power 10 Formula VC Effector is unlikely to cause breakouts for your oily acne-prone skin because it is free of harsh ingredients and includes soothing green tea extract, though a small number of reviewers have reported breakouts. It provides a safe, calming option for oily skin, though its benefits are mostly supportive rather than directly targeting breakouts.
Sources: [European Journal of Pharmaceutics and Biopharmaceutics, 2017](https://pubmed.ncbi.nlm.nih.gov/28385617/), [Clinical, Cosmetic and Investigational Dermatology, 2019](https://pubmed.ncbi.nlm.nih.gov/31239743/)

### Is this serum fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for oily acne-prone skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/oily-acne-prone-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Vitamin C Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-vitamin-c-serum/for/oily-acne-prone-skin) — Superior fit — $25.08 at Amazon
- [NEOGEN DERMALOGY REAL VITA C SERUM](https://lovi.care/skincare/p/neogen-dermalogy/real-vita-c-serum/for/oily-acne-prone-skin) — High fit — $25.08 at Amazon

## Pairs well with

- Cleanser: [CeraVe Foaming Facial Cleanser](https://lovi.care/skincare/p/cerave/foaming-facial-cleanser/for/oily-acne-prone-skin) — Superior fit — $15.97 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/oily-acne-prone-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/oily-acne-prone-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $35.99 (https://www.amazon.com/dp/B0FH46BNGJ?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Water, Butylene Glycol, Glycerin, Polyglutamic Acid, Ascorbyl Tetraisopalmitate, Peg-60 Hydrogenated Castor Oil, Carbomer, Methylparaben, Triethanolamine, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Camellia Sinensis Leaf Extract, Chlorphenesin, Disodium Edta, Dipropylene Glycol, Ethyl Hexanediol, Ethylhexylglycerin
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Ireland: https://lovi.care/skincare/ie/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Germany: https://lovi.care/skincare/de/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- France: https://lovi.care/skincare/fr/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Italy: https://lovi.care/skincare/it/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Netherlands: https://lovi.care/skincare/nl/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Spain: https://lovi.care/skincare/es/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Canada: https://lovi.care/skincare/ca/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Australia: https://lovi.care/skincare/au/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Singapore: https://lovi.care/skincare/sg/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/it-s-skin/power-10-formula-vc-effector/for/oily-acne-prone-skin