Isntree Hyaluronic Acid Watery Sun Gel for oily acne-prone skin

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Questions and answers

What the research says

• Cosmetic formulations containing 5% Centella asiatica extract showed the best efficacy in improving skin moisture and decreasing transepidermal water loss, while also exhibiting antiinflammatory properties in 25 volunteers compared to baseline measurements.

  Indian Journal of Pharmaceutical Sciences, 2016

• The application of a sunscreen formulation containing ethylhexyl methoxycinnamate, ethylhexyl salicylate, methyl anthranilate, and octocrylene does not significantly affect critical acne-related species such as Cutibacterium acnes and Staphylococcus epidermidis, refuting the induction of facial dysbiosis in men.

  Archives of Dermatological Research, 2024

• Co-delivery of paeonol and madecassoside via nanoemulsions improved transdermal delivery, promoted barrier repair proteins, inhibited inflammatory cytokine secretion in cellular and 3D models, and reduced transepidermal water loss and acne in human facial skin compared to free components.

  Molecules, 2023

• Chemical sunscreens containing avobenzone, octocrylene, homosalate, and octisalate showed no to minimal risks of dermal irritation, sensitization, photo-allergy, and photo-irritation in human subjects.

  Journal of Drugs in Dermatology, 2025

• Astaxanthin-loaded polyhydroxybutyrate microbeads achieved 98.1% encapsulation efficiency with sustained release, reduced degradation by 2-fold compared to unencapsulated astaxanthin, and showed no cytotoxicity or skin irritation in human cells and tests.

  International Journal of Biological Macromolecules, 2024

• Topical application of 0.1% hyaluronic acid formulations of different molecular weights led to significant improvements in skin hydration and elasticity, with low-molecular-weight formulations also significantly reducing wrinkle depth in seventy-six female subjects compared to a vehicle control.

  Journal of Drugs in Dermatology, 2011

• Topical application of hyaluronic acid in conjunction with free gingival graft significantly reduced donor site postoperative pain until day 7 compared to normal saline, with no significant differences in graft dimensions or patient satisfaction.

  Clinical Oral Investigations, 2022

• Treatment with a hyaluronic acid-containing mouth rinse or topical gel led to significant lesion reduction, pain relief, and normalization of lesion color in adult patients with minor recurrent aphthous stomatitis, with the gel formulation showing an earlier healing onset at 3 days.

  BMC Oral Health, 2019

• Topical post-laser application of human adipocyte-derived mesenchymal stem cell media combined with niacinamide significantly improved wrinkle index, melanin index, patient satisfaction, and investigator esthetic improvement scores compared to vehicle cream in patients with aging skin.

  Journal of Cosmetic Dermatology, 2021

• Topical nicotinamide prevented solar-simulated UV-induced immunosuppression in healthy volunteers, and men experienced immunosuppression at solar-simulated UV doses three times lower than those required for women.

  The Journal of Investigative Dermatology, 2008

• Topical 5% niacinamide applied twice daily for 12 weeks reduced fine lines and wrinkles, hyperpigmented spots, red blotchiness, and skin sallowness, and improved skin elasticity compared to vehicle control in 50 female white subjects with facial photoaging.

  Dermatologic Surgery, 2005

• Topical application of 0.05% w/w ECa 233 gel reduced erythema index by 0.03 U and improved early crusting and general wound appearance compared to placebo in thirty individuals undergoing facial laser resurfacing.

  Journal of Alternative and Complementary Medicine, 2020

• A single application of a moisturizing fluid containing hyaluronic acid 1%, glycerin 5%, and Centella asiatica stem cells extract significantly increased skin hydration by 29% and reduced transepidermal water loss at 24 hours compared to baseline and an untreated control site in twenty healthy women.

  Clinical, Cosmetic and Investigational Dermatology, 2017

• Moisturizer containing 5% panthenol, madecassoside, and copper-zinc-manganese decreased adverse reactions and downtime after ablative fractional carbon dioxide laser resurfacing with comparable efficacy to 0.02% triamcinolone acetonide cream in 20 subjects.

  Journal of Cosmetic Dermatology, 2019

• Oral astaxanthin supplementation significantly restored moisture content and improved elasticity but did not significantly decrease wrinkle depth compared to placebo in humans.

  Nutrients, 2021

• Combining oral and topical astaxanthin in 30 healthy females improved skin wrinkles, age spots, elasticity, texture, and moisture, while 6 mg daily oral supplementation in 36 healthy males improved crow's feet wrinkles, elasticity, and transepidermal water loss.

  Acta Biochimica Polonica, 2012

• Twice-daily application of a novel topical antioxidant formulation safe, well-tolerated, and effective in improving overall skin quality, fine lines, wrinkles, radiance, and hyperpigmentation in 32 healthy female subjects over 12 weeks.

  Journal of Cosmetic Dermatology, 2023

Ingredients

Water, Butylene Glycol, Ethylhexyl Salicylate, Homosalate, Dibutyl Adipate, Niacinamide, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Cyclopentasiloxane, Methylene Bis-Benzotriazolyl Tetramethylbutylphenol, Polysilicone-15, Diethylamino Hydroxybenzoyl Hexyl Benzoate, 1,2-Hexanediol, Pentylene Glycol, Pinus Pinaster Bark Extract, Ceramide Np, Centella Asiatica Extract, Glycerin, Portulaca Oleracea Extract, Houttuynia Cordata Extract, Olea Europaea Oil Fruit Olive Oil Fruit, Ficus Carica Fruit Extract, Sodium Hyaluronate, Ceteth-10, Hydrogenated Lecithin, Decyl Glucoside, Propanediol, Tocopherol, Astaxanthin, Sodium Hyaluronate Crosspolymer, Ascorbyl Propyl Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydroxypropyltrimonium Hyaluronate, Acrylates C10-30 Alkyl Acrylate Crosspolymer, Sodium Acetylated Hyaluronate, Hydrolyzed Sodium Hyaluronate, Adenosine, Xanthan Gum, Cetyl Peg Ppg-10 1 Dimethicone, Tromethamine, Carbomer, Propylene Glycol, Ethylhexylglycerin

Behind this fit score

Lovi calculates every fit score from the full ingredient list with brand-independent rules our dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update.