# ISDIN Flavo-C Serum for combination skin

**Lovi Fit: High fit for combination skin.**
Combination Skin Fit: High · Effectiveness: Average · Safety: High.

Page: https://lovi.care/skincare/p/isdin/flavo-c-serum/for/combination-skin

The Lovi Fit is the same in every country; only the stores and prices differ, and the ones here are for the United States.

Brand: [ISDIN](https://lovi.care/skincare/brands/isdin)
Category: [Serums and treatments](https://lovi.care/skincare/best/serums)

This fit is calculated for the concerns frequently associated with combination skin: an oily T-zone, enlarged pores, and dry cheeks. For scores based on a full skin profile (12D face scan, goals, preferences), use the Lovi app.

A great choice for combination skin; a few serums fit it even better.

## Why this fit

- Offers excellent antioxidant protection and mild exfoliation for your combination skin, as ascorbic acid and lactic acid work to brighten and refine your complexion.
- Ginkgo biloba leaf extract further supports skin health by providing antioxidant benefits, which are beneficial for managing oily shine.
- The formula is safe for your combination skin, with no risks of irritation due to the absence of prohibited or harsh ingredients.

## Fit by skin type

- [Oily skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/oily-skin): High
- [Dry skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/dry-skin): Average
- [Combination skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/combination-skin): High (this page)
- [Sensitive skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/sensitive-skin): High
- [Acne-prone skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/acne-prone-skin): High
- [Skin with dark spots](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/dark-spots): Average
- [Mature skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/mature-skin): High
- [Dry sensitive skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/dry-sensitive-skin): Average
- [Oily acne-prone skin](https://lovi.care/skincare/p/isdin/flavo-c-serum/for/oily-acne-prone-skin): High

## Key ingredients

Ascorbic Acid, Ginkgo Biloba, Lactic Acid, Propylene Glycol

## What the research says

- A topical serum containing vitamin C, vitamin E, and raspberry leaf cell culture extract improved skin color, elasticity, radiance, smoothness, scaliness, and wrinkles compared to the untreated contralateral side in fifty female volunteers. ([Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/))
- A dermocosmetic containing bakuchiol, Ginkgo biloba extract, and mannitol improves inflammatory lesions, Investigator Global Assessment, and seborrhea intensity when added to adapalene 0.1% gel in patients with acne vulgaris. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/))
- Topical application of 5% vitamin C cream significantly improved global clinical scores, increased skin microrelief density, and induced elastic tissue repair in photoaged skin compared to excipient control in healthy female volunteers. ([Experimental Dermatology, 2003](https://pubmed.ncbi.nlm.nih.gov/12823436/))
- Ascorbic acid 2-glucoside gel significantly reduced gingival melanin pigmentation after 4 weeks compared to placebo in 73 subjects with symmetric pigmentation. ([Journal of Periodontology, 2009](https://pubmed.ncbi.nlm.nih.gov/19186973/))
- Topical application of VC-IP cream twice daily for 8 weeks reduces periorbital wrinkles in female subjects compared to a placebo cream. ([Journal of Cosmetic Dermatology, 2022](https://pubmed.ncbi.nlm.nih.gov/34910367/))
- Topical application of a 2% cream containing combined fruit extracts for 56 days significantly reduced wrinkle depth by 11.5%, length by 10.07%, and area by 29.55% in 21 female subjects compared to a placebo. ([Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/26203268/))
- Topical application of Ginkgo biloba cream for two weeks reduced wrinkles and improved skin shape, texture, and tautness in human volunteers compared to baseline. ([Drug Development and Industrial Pharmacy, 2023](https://pubmed.ncbi.nlm.nih.gov/37074796/))
- A cosmetic formulation combining green tea and Ginkgo biloba extracts synergistically improved skin elasticity and skin barrier function in 48 volunteers compared to individual extracts. ([Journal of Drugs in Dermatology, 2014](https://pubmed.ncbi.nlm.nih.gov/25226010/))
- Application of a cream containing lactic acid 12% and pramoxine HCl 1% significantly improved skin dryness, hydration, and itch compared with a nontreated control in 24 women with a history of dry itchy skin. ([Cutis, 2004](https://pubmed.ncbi.nlm.nih.gov/15027519/))
- Topical 12% ammonium lactate produced a significant sparing of epidermal and dermal atrophy induced by clobetasol propionate in human volunteers, without influencing the corticosteroid's bioavailability or antiinflammatory properties. ([Journal of the American Academy of Dermatology, 1992](https://pubmed.ncbi.nlm.nih.gov/1597538/))
- A lactic acid/ceramide lotion significantly improved skin moisturization and desquamation compared to no treatment in women with dry, rough skin on the anterior shins. ([The Journal of Clinical and Aesthetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/33178384/))
- Treatment with a combination of propylene glycol, ethanol, water, and shampoo was found effective, easy to use, and cosmetically attractive with no observed side effects in patients with dandruff. ([Cutis, 1988](https://pubmed.ncbi.nlm.nih.gov/2970946/))
- A moisturizer containing glycerol and propylene glycol reduced transepidermal water loss, decreased epidermal thickness, increased stratum corneum thickness, and reduced dermal inflammatory infiltrate compared to untreated disrupted skin in six healthy beagle dogs. ([Veterinary Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/32628309/))

## What reviewers say

This serum is highly regarded for its ability to brighten dull skin, reduce hyperpigmentation, and smooth fine lines, making it particularly effective for mature, dehydrated, or sun-damaged complexions. The formula is frequently praised for being lightweight and fast-absorbing, and for providing significant hydration. A small number of users with sensitive skin have reported experiencing irritation or redness.

- Liked: Brightens skin tone (often mentioned)
- Liked: Hydrates and smooths (often mentioned)
- Liked: Lightweight, fast-absorbing (sometimes noted)
- Disliked: Frustrating packaging (rarely noted)
- Disliked: Irritates sensitive skin (rarely noted)
- Disliked: Unpleasant smell (rarely noted)

## How to apply

- Use your serum as part of your PM routine. Start using it 3 times a week and move to daily use if your skin likes it.
- Apply the serum after cleansing and toner, and right before your moisturizer.
- Gently press 2-3 drops of the serum into your skin and wait a minute ⏳for it to soak in.
- Apply the serum on clean and dry skin since your skin is not sensitive.
- Always do a patch test before using the serum for the first time, and avoid the eye area .
- Video: https://storage.pora.ai/c879dda8655a61c19d3d8c9ebad6b06d.mp4

## Questions and answers

### What makes ISDIN Flavo-C a great fit for combination skin?

ISDIN Flavo-C Serum is a great fit because ascorbic acid and lactic acid brighten your complexion while offering mild exfoliation and antioxidant protection. Ginkgo biloba leaf extract further supports skin health and helps manage oily shine, all with a safe formula that is unlikely to cause irritation.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Which ingredients make this serum a good fit for combination skin?

Ascorbic acid and lactic acid make this serum a great fit by offering antioxidant protection and mild exfoliation to brighten and refine your skin. Ginkgo biloba leaf extract further supports your skin by providing antioxidant benefits that help manage oily shine.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Vitamin C do for combination skin?

Vitamin C helps brighten dull areas and smooth out uneven texture on combination skin while protecting against daily environmental stress. It may also help keep pores clear and skin firm by supporting collagen production, though drier spots may need an added moisturizer to stay comfortable.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### What does Ginkgo Biloba Extract do for combination skin?

Ginkgo Biloba Extract helps calm combination skin and protects it from daily stress. It also improves skin texture and smoothness while keeping the skin looking fresh.
Sources: [Drug Development and Industrial Pharmacy, 2023](https://pubmed.ncbi.nlm.nih.gov/37074796/), [Journal of Dermatological Science, 2014](https://pubmed.ncbi.nlm.nih.gov/24802711/)

### Where does this serum go in a skincare routine for combination skin?

This serum goes in the evening routine after cleansing and before moisturizing, as Lovi routines put treatments in the evening for simplicity and safety around sun exposure. It helps brighten and refine combination skin with ascorbic acid and lactic acid.

### Can I use it with retinol, and in what order?

You can use this treatment with retinol by applying your retinol in the evening and keeping this vitamin C serum for your morning routine, which helps prevent any extra sensitivity. Using antioxidant serums in the morning is a great way to protect your skin throughout the day while keeping your nighttime routine focused on retinol.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### How often should I use it?

Start by using this treatment once a week in the evening routine, and if your skin tolerates it well and shows good results, you can carefully use it more often. This gentle approach helps safely manage your combination skin while refining your complexion and providing antioxidant protection.
Sources: [Journal of Cosmetic Dermatology, 2020](https://pubmed.ncbi.nlm.nih.gov/31975502/)

### Can this serum clog pores, cause breakouts or purging for combination skin?

ISDIN Flavo-C Serum is unlikely to clog pores or cause breakouts on combination skin because its formula avoids heavy, pore-clogging ingredients. The inclusion of lactic acid and ginkgo biloba helps keep your complexion clear and refined by gently managing excess oil and dead skin cells.
Sources: [Clinical, Cosmetic and Investigational Dermatology, 2015](https://pubmed.ncbi.nlm.nih.gov/25914553/)

### Is it fragrance-free and alcohol-free?

Yes, it has no fragrance and no drying alcohol.

## Alternatives for combination skin

- [Beauty of Joseon Propolis + Niacinamide Glow Serum](https://lovi.care/skincare/p/beauty-of-joseon/propolis-niacinamide-glow-serum/for/combination-skin) — Superior fit — $16.75 at Amazon
- [Neogen Dermalogy Real Niacinamide 15% Firming Serum](https://lovi.care/skincare/p/neogen-dermalogy/real-niacinamide-15-firming-serum/for/combination-skin) — Superior fit — $28.88 at Amazon
- [Augustinus Bader The Serum](https://lovi.care/skincare/p/augustinus-bader/the-serum/for/combination-skin) — Superior fit — $200.00 at Amazon

## Pairs well with

- Cleanser: [Fresh Soy Face Cleanser](https://lovi.care/skincare/p/fresh/soy-face-cleanser/for/combination-skin) — Superior fit — $28.08 at Amazon
- Hydrating Toner: [Paula's Choice Pore-Reducing Toner](https://lovi.care/skincare/p/paula-s-choice/skin-balancing-pore-reducing-toner/for/combination-skin) — Superior fit — $25.60 at Amazon
- Moisturizer: [COSRX Oil-Free Ultra-Moisturizing Lotion with Birch Sap](https://lovi.care/skincare/p/cosrx/oil-free-ultra-moisturizing-lotion-with-birch-sap/for/combination-skin) — Superior fit — $18.99 at Amazon

## Where to buy

- Amazon.com: $115.00 (https://www.amazon.com/dp/B01BMLQ086?tag=lovi-care-web-product-20&linkCode=osi&th=1&psc=1)
Prices checked 5 Nov 2026.

## Ingredients

Propylene Glycol, Water, Ginkgo Biloba Leaf Extract, Ascorbic Acid, Polysorbate 20, 2-Hexanediol, Polysorbate 80, Phenoxyethanol, Lactic Acid, Sodium Hydroxide, Ginkgo Biloba
## About the Lovi Fit

Lovi: Unbiased, science-based skincare AI trained on real user outcomes.

Lovi calculates every fit score from the full ingredient list with brand-independent rules its dermatologists and cosmetic chemists build and review, and personalizes every pick with AI trained on the real results of millions of users. Lovi trains its fit score models on a proprietary dataset built from more than 10,000 expert-labeled products and more than 100,000 simulated examples, following an internally consistent methodology presented at Cosmoprof, AMWC, and Skin of Color Update. Levels from best to worst: Superior, High, Average, Low, Caution, Warning.

Behind this fit score: Nadia Kapleva, MS (Co-founder, Medical Director); Alexey Shagraev, PhD (Co-founder, CEO and CTO); Dr. Sofía Perea Pérez, MD, MSc (Medical Board); Aishani Shah, MD (Medical Board); Asya Zubkova, MS (Medical Board); Hanna Kurets, MD (Medical Board, Medical Advisor); Elina Nazarenko, MD (Medical Board); Victoria Derkova, MS (Medical Board).

Page built Nov 8, 2026.

More from Lovi: https://lovi.care/skincare/llms.txt

## This page in other countries

- United States: https://lovi.care/skincare/p/isdin/flavo-c-serum/for/combination-skin (this page)
- United Kingdom: https://lovi.care/skincare/uk/p/isdin/flavo-c-serum/for/combination-skin
- Ireland: https://lovi.care/skincare/ie/p/isdin/flavo-c-serum/for/combination-skin
- Germany: https://lovi.care/skincare/de/p/isdin/flavo-c-serum/for/combination-skin
- France: https://lovi.care/skincare/fr/p/isdin/flavo-c-serum/for/combination-skin
- Italy: https://lovi.care/skincare/it/p/isdin/flavo-c-serum/for/combination-skin
- Netherlands: https://lovi.care/skincare/nl/p/isdin/flavo-c-serum/for/combination-skin
- Spain: https://lovi.care/skincare/es/p/isdin/flavo-c-serum/for/combination-skin
- Canada: https://lovi.care/skincare/ca/p/isdin/flavo-c-serum/for/combination-skin
- Australia: https://lovi.care/skincare/au/p/isdin/flavo-c-serum/for/combination-skin
- Singapore: https://lovi.care/skincare/sg/p/isdin/flavo-c-serum/for/combination-skin
- Saudi Arabia: https://lovi.care/skincare/sa/p/isdin/flavo-c-serum/for/combination-skin
- United Arab Emirates: https://lovi.care/skincare/ae/p/isdin/flavo-c-serum/for/combination-skin